New research from Intermountain Health in Salt Lake City finds that patients diagnosed with peripheral arterial disease (PAD) who also have atrial fibrillation (AFib) face a significantly higher risk of major adverse cardiovascular events (MACE). The Intermountain study analyzed long-term data of Intermountain Health patients with PAD and found that AFib was present in approximately one in four PAD patients, making this combination far more common than previously recognized. More importantly, Intermountain researchers found the presence of AFib nearly doubles the risk of major adverse cardiovascular events in patients compared to PAD alone. Irregular heart rhythms are called arrhythmias. ...

While some risk factors for cancer can be mitigated through lifestyle choices such as diet or exercise, aging is not one of them. In the case of pancreatic cancer, it also can limit treatment options if a patient is too frail to be safely treated with surgery or other alternatives. Scientists at the NCI-Designated Cancer Center at Sanford Burnham Prebys Medical Discovery Institute would like to expand options for these patients with personalized treatments. Many stand to benefit from a therapeutic strategy that factors in age. The average age of a patient diagnosed with pancreatic cancer is 70, and nearly two-thirds of cases are in people over the age of ...

A psychedelic found in mushrooms is emerging as a potential treatment for alcohol use disorders. This possibility is due to a compound the body converts the psychedelic into called psilocin, but psilocin’s mechanisms remain unclear. Researchers, led by Sarah Magee and Melissa Herman at University of North Carolina at Chapel Hill, explored whether psilocin targets neurons in the central amygdala involved in emotional processing and stress to alter alcohol use in their JNeurosci paper. Herman emphasizes that ...

In a new JNeurosci paper, Sarah Jessen and colleagues, from the University of Lübeck, explored how infants track their mothers’ voices compared to unfamiliar voices. The researchers also explored whether this vocal processing affects how babies process new faces.  Brain recordings of babies around 7 months old showed that they were far more attuned to the voices of their mothers than strangers. Additionally, neural tracking of unfamiliar faces was stronger when babies heard a stranger’s voice compared to their mother’s voice at the same time. Whether a face ...

In a new JNeurosci paper, Kahori Kita and colleagues at Johns Hopkins University explored how people switch between intuitive motor skills they know and newly learned movement patterns.  Study volunteers frequently made errors switching between more innate movements and new ones. These errors were largely because people persistently stuck to the movement patterns they used before the switch. Notes Kita, “People made similar errors when switching from the intuitive to the new skill, as when switching from the new skill to the intuitive one.” A second group of people learned two new movement-based skills. It was initially even more difficult for these ...

A new native bee species with tiny devil-like “horns” named Megachile (Hackeriapis) lucifer has been discovered in Western Australia’s Goldfields, highlighting how much remains unknown about Australia’s native pollinators. The striking new bee was found during surveys of a critically endangered wildflower Marianthus aquilonarius that grows only in the Bremer Range region, which is between the towns of Norseman and Hyden. Lead author Curtin Adjunct Research Fellow Dr Kit Prendergast, from the Curtin School of Molecular and Life Sciences, said the female bee’s unusual ...

About The Article: This Viewpoint describes the U.S. Food and Drug Administration’s intended label updates and removal of black box warnings for menopausal hormone therapy based on current evidence. Corresponding Author: To contact the corresponding author, Martin A. Makary, MD, MPH, email commissionersoffice@fda.hhs.gov. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2025.22259) Editor’s Note: Please see the article for additional ...

ST. LOUIS, MO, November 10, 2025 - A new collaborative research team of plant scientists led by Ru Zhang, PhD, associate member, Danforth Plant Science Center has been awarded new funding from the National Science Foundation to investigate how photosynthetic cells retain “heat stress memory” (HSM), a key adaptive mechanism that could help future crops withstand intense and frequent heat waves.  Photosynthesis, the process by which plants convert sunlight into energy, is the key driver of plant growth ...

Researchers at the University of California San Diego School of Medicine have developed a new approach for identifying individuals with skin cancer that combines genetic ancestry, lifestyle and social determinants of health using a machine learning model. Their model, more accurate than existing approaches, also helped the researchers better characterize disparities in skin cancer risk and outcomes. Skin cancer is among the most common cancers in the United States, with more than 9,500 new cases diagnosed every day and approximately ...

November 10, 2025— Adults who experience poverty-level family income—whether sustained or intermittent—over two decades spanning young to mid-adulthood face a significantly higher risk of dying prematurely than those who are never in poverty, according to new research led by Columbia University Mailman School of Public Health. A companion study by the same research team finds that rising unsecured debt—such as credit card debt not tied to an asset—may be one mechanism linking early-life financial hardship to ...

NEW YORK, NY, November 10, 2025 – An interdisciplinary team of scientists at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) has unveiled a groundbreaking conceptual model and integrative monitoring framework designed to reveal how climate change is stressing life across the planet. Their study, published this week in Cell Reports Sustainability, introduces the concept of the Climate BioStress model and proposes the adoption of an integrative Climate BioStress Sentinel System (CBS3), which could transform how researchers, policymakers, ...

Few primary care practices are designed for the timely detection of Alzheimer’s disease and related dementias. The limited time that primary care clinicians are able to spend with patients, the need to focus on the health problems which brought the patient to the clinic, as well as the stigma of Alzheimer’s disease and dementia are major reasons for lack of recognition of the condition. Researchers have demonstrated that a fully digital artificial intelligence zero-cost method for detecting dementia can be scaled across primary care clinics without ...

PROVIDENCE, R.I. [Brown University] — A federally funded clinical trial to evaluate an intervention to prevent suicides among people recently released from jail reduced suicide attempts by 55%. That’s according to a new study in JAMA Network Open led by researchers from Brown University and Michigan State University. In the United States, one in five adults who attempts suicide has spent at least one night in jail in the year prior. With more than 10 million admissions per year and many stays of just a few days, jails touch a significant number of people at high risk for suicide who are not well connected with other support services. This ...

About The Study: U.S. individuals ages 1 to 19 are now more likely to die by firearm injury than any other cause. While this national shift occurred in 2019, Alaska had already flipped as early as 2004. Over the past 2 decades, more states flipped to firearm mortality as the predominant cause of death in this age group, including nearly half of the states in the most recent era reviewed. Corresponding Author: To contact the corresponding author, Michael L. Nance, MD, email nance@chop.edu. To ...

About The Study: In this cross-sectional study of homicides among women, state-level firearm ownership was significantly associated with all-cause and firearm-specific homicide among pregnant women, independent of state-level factors. These results suggest that homicide prevention interventions should focus on women, especially during the increased risk period of pregnancy.  Corresponding Author: To contact the corresponding author, Ayesha Dholakia, MD, email ayesha.dholakia@childrens.harvard.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.42447) Editor’s ...

Investigators at Mass General Brigham have found that cases of child abuse and neglect in the United States have declined overall over the last decade, but disparities have persisted and in some cases widened. Poverty, which likely underlies much of the observed gaps, was highlighted as a critically important target for intervention. The research is published in JAMA Pediatrics.   “Poverty is a relentless source of stress that permeates families, creating an environment where the struggles for survival may overshadow the nurturing ...

Osaka, Japan - A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered a new molecular mechanism underlying chromosome alignment during cell division. The study demonstrates that two motor proteins, KIF18A and CENP-E, act cooperatively to ensure proper chromosome congression. Remarkably, simultaneous inhibition of these proteins selectively kills cancer cells, suggesting a promising therapeutic avenue. Accurate chromosome segregation is essential for healthy cell division; its failure leads to chromosomal instability—a hallmark of cancer. While the kinetochore, a protein complex on chromosomes, coordinates this ...

The American College of Medical Genetics and Genomics (ACMG) has published a new clinical practice resource, “Management of Individuals with Heterozygous Germline Pathogenic Variants in RAD51C, RAD51D, and BRIP1: A clinical practice resource of the American College of Medical Genetics and Genomics (ACMG),” in its official journal, Genetics in Medicine. The publication provides evidence-based guidance for clinicians managing individuals with heterozygous germline pathogenic variants (GPVs) in RAD51C, ...

One of the most devastating moments for family members of a patient with Alzheimer’s is when their loved one forgets who they are. New University of Virginia School of Medicine research may explain why that happens and could lead to a way to prevent it. UVA’s Harald Sontheimer, PhD, and graduate student Lata Chaunsali and their colleagues found that the failure to recognize family, friends and caregivers is caused by the breakdown of protective “nets” that surround neurons in the brain. ...

“This environmentally friendly technique represents a novel approach to nanoparticle fabrication, emphasizing sustainability in nanotechnology.” BUFFALO, NY – November 10, 2025 – A new research paper was published in Oncotarget (Volume 16) on November 6, 2025, titled “Anti-DNA virus agent cidofovir – loaded green synthesized cerium oxide nanoparticles (Nanoceria): Nucleic acids (DNA and RNA) binding affinity and cytotoxicity effects.” In ...

What factors help English learners (ELs) succeed in schools? In a study of top performing New York City high schools serving immigrant ELs, researchers linked three conditions—teacher autonomy, collaboration, and collective responsibility—to higher credit attainment. “Most research on ELs focuses on classroom instruction or broader language policies, but our study describes the professional conditions that positively impact outcomes for immigrant ELs,” says Adriana Villavicencio, lead author and assistant professor of educational leadership and policy studies at NYU Steinhardt. “We took this approach to address a dearth ...

In 2023, astronomers detected a huge collision. Two unprecedentedly massive black holes had crashed an estimated 7 billion light-years away. The enormous masses and extreme spins of the black holes puzzled astronomers. Black holes like these were not supposed to exist. Now, astronomers with the Flatiron Institute’s Center for Computational Astrophysics (CCA) and their colleagues have figured out just how these black holes may have formed and collided. The astronomers’ comprehensive simulations — which follow the system from the lives of the parent stars through to their ultimate death — uncovered ...

Blue Zones and the American College of Lifestyle Medicine (ACLM) today launched the “Blue Zones Certification Course for Physicians and Health Professionals.” The new certification recognizes clinicians with the knowledge and tools to promote longevity, well-being, and health equity—both in the exam room and in their communities. The certification integrates Blue Zones' evidence-based roadmap to living better and longer, rooted in their identification of and research from the world's longest-lived and happiest cultures—the blue zones regions—with ACLM's ...

SAN ANTONIO — November 10, 2025 — Southwest Research Institute (SwRI) has demonstrated a new application for its cell-expansion bioreactor to advance tissue engineering and cell-based therapies for treatment of injuries and diseases. SwRI scientists used the bioreactor to replicate induced Pluripotent Stem Cells (iPSCs) derived from adult skin, blood, and other somatic cells. Their pluripotent state allows iPSCs to differentiate into any other cell type in the body, much like embryonic stem cells but without the same ethical ambiguity. Large quantities ...

Trial Showing Ivermectin Safety in Small Children Could Spur Progress Against Several Neglected Tropical Diseases TORONTO (November 10, 2025)—Millions of very young children currently excluded from treatment with the drug ivermectin could be safely included in ongoing campaigns against challenging and often neglected tropical diseases such as intestinal worms, scabies and river blindness, according to results from a clinical trial presented today at the Annual Meeting of the American Society ...