SOMERVILLE, Mass., November 13, 2025 – Cellarity, a clinical-stage biotechnology company developing Cell State-Correcting therapies through integrated multi-omics and AI modeling, today announced the publication of a seminal manuscript in Nature Communications, which describes a novel framework for the prediction and characterization of drug-induced liver injury (DILI), along with open-source posting of the model and validation data. DILI is one of the most significant safety challenges in developing therapeutics today, as hepatic safety events undetected in preclinical testing ...

In the summer of 2022, 20 islands in the Maldives were flooded when a distant swell event in the Indian Ocean coincided with an extremely high tide level. A new and detailed analysis of that incident, compiled using fieldwork and computer modelling, has shown it to be a relatively rare occurrence with the worst flooding seen in the region since the Boxing Day tsunami of 2004. However, scientists have warned that future predicted rises in sea levels, potentially coupled with an increase in extreme weather events and wave conditions, could result in such flooding becoming far more common, perhaps happening every two to three years by around 2050. It has led them to ...

The Synapsy Centre for Neuroscience Research in Mental at the University of Geneva (UNIGE) Faculty of Medicine has awarded its first prize to Professor Eric Nestler, a leading figure in the neurobiology of depression and addiction. The prize recognises a career dedicated to linking fundamental discoveries about the brain to concrete clinical advances in mental health. Psychiatry has been evolving over the past twenty years. Driven by a new scientific ambition, it seeks to understand the biological mechanisms underlying mental disorders to improve their diagnosis and treatment. This translational approach aims to foster dialogue ...

Emotional support is an increasingly common reason people turn to generative artificial intelligence chatbots and wellness applications, but these tools currently lack the scientific evidence and the necessary regulations to ensure users’ safety, according to a new health advisory by the American Psychological Association. The APA Health Advisory on the Use of Generative AI Chatbots and Wellness Applications for Mental Health examined consumer-focused technologies that people are relying on for mental health advice and treatment, ...

The unforeseen consequences of modern lifestyles are coming to the forefront as healthcare costs spike in developed countries worldwide. One method to mitigate this is to encourage walking to promote good health. Therefore, initiatives to increase daily steps have been taking shape and becoming subjects for in-depth study. Dr. Haruka Kato, a junior associate professor at Osaka Metropolitan University, with policy planners from the Sakai City Government investigated the ...

LOS ANGELES — Keck Hospital of USC and USC Verdugo Hills Hospital (USC-VHH) each earned a Fall 2025 “A” Hospital Safety Grade from The Leapfrog Group, an independent national nonprofit focused on patient safety. The hospitals are part of Keck Medicine of USC, the University of Southern California’s health system.   “This is the first time the health system has received two ‘A’s simultaneously, which is a huge accomplishment,” said Rod Hanners, CEO of Keck Medicine. “The Leapfrog Group grades hospitals ...

Affective computing, proposed by Picard in 1997, aims to endow computational systems with the ability to recognize, interpret, and respond to human emotions. Early studies relied primarily on behavioral cues such as facial expressions and voice tone for modelling affective states. Affective computing has entered a new phase—wearable devices are capable of continuously acquiring multimodal physiological signals from multiple sensor channels that differ in terms of sampling frequency, physiological origin, and signal characteristics. In ...

A newly discovered, carnivorous lizard ostensibly represents what most casual onlookers would perhaps perceive to be a dinosaur; however, it is in fact a precursor of the modern crocodile. Named Tainrakuasuchus bellator, partially derived from Latin meaning for “warrior” or “fighter”, this armour-plated reptile lived 240 million years ago just before the dinosaurs. And, as a Pseudosuchia (the precursors of modern crocodiles and alligators), it was among a group of the top, most dominant predators of its time in the Triassic Period. This particular new species – detailed, today, in the peer-reviewed Journal of Systematic Palaeontology – was approximately ...

As artificial vision systems evolve, bridging the gap between sensing and processing remains a key challenge. Now, researchers from the University of Science and Technology of China, led by Prof. Yong Yan and Prof. Haiding Sun, have developed a reconfigurable bioinspired vision sensor using GaN/AlN quantum-disk-in-nanowires (QD-NWs) that emulates the human retina’s dual-cell system—delivering in-sensor computing for high-accuracy human action recognition (HAR). Why This Bioinspired Sensor Matters Dual-Mode ...

Nuclear fusion, which operates on the same principle that powers the Sun, is expected to become a sustainable energy source for the future. To achieve fusion power generation, it is essential to confine plasma at temperatures exceeding one hundred million degrees using a magnetic field and to maintain this high-energy state stably.  A key factor in accomplishing this is the electric potential inside the plasma. This potential governs the transport of particles and energy within the plasma and plays a crucial role in establishing a state in which energy is effectively confined and prevented ...

CHAMPAIGN, Ill. — A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report. The protein, FGD3, contributes to the rupture of cancer cells disrupted by these drugs, boosting their effectiveness and enhancing anticancer immunotherapies. The discovery is described in the Journal of Experimental & Clinical Cancer Research. The new findings were the happy result of experiments involving ErSO, an experimental drug that killed 95-100% of estrogen-receptor-positive ...

A widely-used, inexpensive gout drug could reduce heart attacks and strokes in people with cardiovascular disease, according to a new Cochrane review. The review examined the effects of low doses of colchicine, a drug used to treat gout, and found no increase in serious side effects. Cardiovascular disease is often driven by chronic low-grade inflammation, which contributes to recurrent cardiovascular events such as heart attacks and strokes. Colchicine has anti-inflammatory properties that make it a promising option for people with heart disease.  A promising effect on cardiovascular risk The review included 12 randomized controlled trials involving nearly 23,000 ...

EMBARGOED: Hold for release until Wednesday, Nov. 12 at 18:30 ET / 23:30 UK time     Headache disorders affect 3 billion people worldwide—nearly one in every three people, ranking sixth for health loss in 2023  Women experienced more than twice the headache-related health loss of men and spent a greater share of their lives with headache symptoms. Migraine caused nearly 90% of all disability linked to headache disorders, even though tension-type headache was more common.  More than one-fifth of the global headache burden ...

ROCHESTER, Minn. — Mayo Clinic researchers have developed a new tool that can estimate a person's risk of developing memory and thinking problems associated with Alzheimer's disease years before symptoms appear. The research, published in The Lancet Neurology, builds on decades of data from the Mayo Clinic Study of Aging — one of the world's most comprehensive population-based studies of brain health. The study found that women have a higher lifetime risk than men of developing dementia and mild cognitive impairment (MCI), a transitional stage between healthy aging and dementia ...

Extending anti-clotting drugs beyond the initial treatment period of at least 90 days after a first blood clot is linked to lower rates of new clots developing compared with stopping treatment, finds a US study published by The BMJ today. Extended treatment was also linked to higher rates of major bleeding (a common side effect of anti-clotting drugs) but the authors say continued use results in an overall “net clinical benefit.” Guidelines recommend anti-clotting treatment for at least 3-6 months for patients with venous thromboembolism ...

Exposing children to e-cigarettes compromises their human rights. These products should be regulated in a way that puts children’s best interests first and protects them from the harms associated with nicotine consumption in all its forms, argue experts in The BMJ today. Children are now using e-cigarettes at higher rates than adults, write Tom Gatehouse and colleagues. Globally, the World Health Organization (WHO) estimates that 7.2% of children aged 13-15 currently use e-cigarettes. Data indicate use in this group is nine times that of adults, in countries which monitor both groups.  As ...

The rate of high blood pressure (hypertension) in children and adolescents under 19 has nearly doubled, increasing from about 3% in 2000 to over 6% in 2020. More than 9% of children and adolescents have masked hypertension — high blood pressure that only shows up with out-of-office tests, meaning hypertension could be undetected during regular checkups. Nearly 19% of children and adolescents with obesity have hypertension, eight times higher than the prevalence of hypertension in those considered a healthy weight. Approximately 8% of children and adolescents now have prehypertension, a warning sign of potential progression to hypertension, which ...

Seattle, United States & Seoul, Republic of Korea—PATH and EuBiologics Co., LTD are pleased to announce Phase 3 results from a clinical trial of a typhoid conjugate vaccine (TCV), EuTYPH-C Inj.® Multi-dose. EuTYPH-C Inj.® Multi-dose is manufactured by EuBiologics Co., LTD, Republic of Korea. The results, published in The Lancet Global Health, demonstrate that EuTYPH-C Inj.® Multi-dose is safe and immunogenic in typhoid-endemic populations in sub-Saharan Africa. The study was conducted at sites in Kenya and Senegal in healthy ...

Global carbon emissions from fossil fuels are projected to rise by 1.1% in 2025 – reaching a record high, according to new research by the Global Carbon Project. The 2025 Global Carbon Budget projects 38.1 billion tonnes of fossil carbon dioxide (CO2) emissions this year. Decarbonisation of energy systems is progressing in many countries – but this is not enough to offset the growth in global energy demand. With projected emissions from land-use change (such as deforestation) down to 4.1 billion ...

A fundamental rethink of how the NHS trains its future workforce is urgently needed, according to a new paper from the Higher Education Policy Institute (www.hepi.ac.uk), Rethinking Placement: Increasing Clinical Placement Efficacy for a Sustainable NHS Future (HEPI Report 194). The paper, written by senior leaders from the University of East London (UEL), argues that the National Health Service (NHS) cannot achieve its ambitious workforce goals without bold system-wide reform of how students gain real-world experience – the essential bridge between classroom learning and frontline care. The HEPI Report, which has been published with the support of the Council for Deans ...

Most commonly reported error in the physical exam is that the exam was never performed Report in the New England Journal of Medicine is part of a six-issue series on medical education ‘If we don’t intentionally cultivate these bedside skills, they’re at risk of being lost’ CHICAGO --- Today’s doctor visits look and feel a lot different than they did even just a couple decades ago.  Rushed physicians and medical trainees are spending less time with patients, leading to diagnostic errors, ...

New York, NY (November 12, 2025) – A new study from the Icahn School of Medicine at Mount Sinai helps explain why some people with multiple myeloma, a type of blood cancer, stay in remission for many years after receiving CAR T cell therapy, while others see their cancer return sooner. Published in Blood Advances, the research is the first longitudinal, single-cell, multi-omic study of cilta-cel in multiple myeloma. Cilta-cel (ciltacabtagene autoleucel) is a type of CAR T cell therapy used to treat relapsed or refractory multiple myeloma. It works ...

As climate change increases the frequency of droughts, UCLA and UC Davis researchers found one overlooked side effect: People report more conflicts with wildlife during drought, when resources are scarce. For every inch that annual rainfall decreases, scientists found a 2% to 3% increase in reported clashes with a variety of carnivores during drought years, according to a paper published today, Nov. 12, in the journal Science Advances.  The researchers pored through seven years of data from the Wildlife Incident Reporting database, run by the California Department of Fish and Wildlife. The results are likely broadly applicable outside of California, said lead author Kendall Calhoun, ...

Mutations drive evolution, but they can also be risky. New research led by plant biologists at the University of California, Davis, published Nov. 10 in Proceedings of the National Academy of Sciences, reveals how plants control mutation rates in different stem cells to balance adaptability with safety and stability. The findings have implications for breeding some of the world’s most important fruit and vegetable crops, such as potatoes and bananas.  The researchers showed that DNA mutations accumulated up to 4.5 times more frequently in the stem cells that produce a plant’s ...

The Cyvia and Melvyn Wolff Center for Entrepreneurship in the University of Houston’s C.T. Bauer College of Business has once again been named the No. 1 undergraduate entrepreneurship program. The Wolff Center is the first undergraduate program to secure seven consecutive No. 1 rankings on The Princeton Review’s list, besting its own record of six consecutive wins in the 2025 ranking last November. Each year, The Princeton Review ranks undergraduate and graduate entrepreneurship programs based on a survey of nearly 300 schools across the U.S., Canada, Mexico and Europe. ...