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Pediatric Academic Societies awards 33 Trainee Travel Grants for the PAS 2025 Meeting

2025-04-21
Honolulu, Hawaii — The Pediatric Academic Societies (PAS) are proud to announce the recipients of the prestigious PAS Trainee Travel Grants, recognizing 33 exceptional trainees for their contributions to pediatric research. Each award includes complimentary registration to the PAS 2025 Meeting in Honolulu, Hawaii, and a $500 travel grant to support their participation. These awards aim to encourage emerging talent and recognize excellence in pediatric research. Awardees were selected based on the quality of their submitted abstracts, with ...

Advancing understanding of lucid dreaming in humans

2025-04-21
Lucid dreaming is a surreal phenomenon in which people are consciously aware that they are in a dream. Çağatay Demirel, from Donders Center for Cognitive Neuroimaging, Radboud University Medical Center, and colleagues shed light on the neural correlates of lucid dreaming in their JNeurosci paper.   The researchers used a rigorous processing pipeline as they collected and assembled data from multiple labs to create what is, according to the authors, the largest sample size to date for this field of research. Comparisons of brain activity during lucid dreaming, rapid eye movement sleep, and wakefulness revealed distinct activity patterns for ...

Two brain proteins are key to preventing seizures, research in flies suggests

2025-04-21
One in ten people will have at least one seizure in their life, but effective treatments for seizures remain very limited, in part due to incomplete understanding of the brain mechanisms involved. Now, research in fruit flies has uncovered a role for two specific brain proteins that are necessary during brain development to prevent seizures. The two proteins, Imp and Sdc, are found in the developing brains of both flies and mammals, and are involved in the growth and development of neurons and brain circuits. A reduction of either protein during development makes flies prone to seizures without otherwise affecting their ability to move, the researchers found. ...

From research to real-world, Princeton startup tackles soaring demand for lithium and other critical minerals

2025-04-21
Tracing its roots to fundamental research conducted at Princeton, a new startup is upending decades-old approaches for the way the world extracts lithium and other materials, including nitrate and potash, that power today’s clean energy technologies and support modern agriculture. The company, Princeton Critical Minerals (formerly PureLi), which emerged from the University’s ecosystem for innovation and entrepreneurship, has developed a technology for boosting minerals production from evaporation ponds. These ponds currently generate around 40% of the world’s lithium and most of its naturally occurring nitrate. The technology is a black disc with a special, ...

Can inpatient psychiatric care help teens amid a depressive crisis?

2025-04-21
There has been a troubling rise in adolescent mental health struggles and suicide rates over the past decade, with a dramatic increase following the start of the COVID-19 pandemic. This crisis has been accompanied by an increased demand for pediatric inpatient psychiatry units (IPUs) across the United States. However, despite the growing need, which has reached the point of bed shortages, the effectiveness of IPUs on teen mental health outcomes remains understudied. This study, led by Dr. Patricia Ibeziako from Boston Children’s Hospital, reviewed the electronic medical records ...

In kids, EEG monitoring of consciousness safely reduces anesthetic use

2025-04-21
Newly published results of a randomized, controlled clinical trial in Japan among more than 170 children aged 1 to 6 who underwent surgery, show that by using EEG readings of brain waves to monitor unconsciousness, an anesthesiologist can significantly reduce the amount of the anesthesia administered to safely induce and sustain each patient’s anesthetized state. On average the little patients experienced significant improvements in several post-operative outcomes, including quicker recovery and reduced incidence of delirium. “I think the main takeaway is that in kids, using the EEG, we can reduce the amount of anesthesia we give them and maintain the same level of unconsciousness,” ...

Wild chimps filmed sharing ‘boozy’ fruit

2025-04-21
For the first time, wild chimpanzees have been pictured eating and sharing fruit containing alcohol. A research team led by the University of Exeter set up cameras in Guinea-Bissau’s Cantanhez National Park. Footage of chimps sharing fermented African breadfruit – confirmed to contain ethanol (alcohol) – raises fascinating questions about if and why chimps deliberately seek out alcohol. Humans are believed to have consumed alcohol far back into our evolutionary history, with benefits for social bonding. And the new study suggests our closest relatives might be doing something ...

Anxiety and depression in youth increasing prior, during and after pandemic

2025-04-21
The percentage of children under 18 years old with anxiety and depression increased steadily from 2016 to 2022, according to publicly available data from the National Survey of Children’s Health that were analyzed by researchers from Ann & Robert H. Lurie Children’s Hospital of Chicago. In contrast, there was no increase during that timeframe related to physical health problems, such as asthma, severe headache or migraine, and heart conditions. Results were published in JAMA Pediatrics. “Our findings underscore the critical need to prioritize youth mental health, which continued to worsen even as ...

Trends in mental and physical health among youths

2025-04-21
About The Study: In this large, nationally representative sample of U.S. youths, the proportions of youths with anxiety or depression increased from 2016 to 2022. In contrast, youth physical health conditions like asthma and severe headache or migraine decreased, while behavioral or conduct problems and heart conditions were consistent. These findings suggest that deterioration in youth health was specific to depression and anxiety but not select physical health conditions. This study aimed to characterize trends in youth health ...

Burnout trends among US health care workers

2025-04-21
About The Study: In this survey study of Veterans Health Administration (VHA) health care workers, burnout and professional stress decreased on average following the pandemic, but burnout levels remain elevated compared with prepandemic levels. The VHA has made several efforts to reduce burnout and stress, and results showed some promise, but exploration of ways to reduce burnout to prepandemic levels is needed. Corresponding Author: To contact the corresponding author, David C. Mohr, PhD, email david.mohr2@va.gov. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.5954) Editor’s ...

Transcranial pulsed current stimulation and social functioning in children with autism

2025-04-21
About The Study: In this randomized clinical trial of prefrontal-cerebellar transcranial pulsed current stimulation in children ages 3 to 14 with autism spectrum disorder, 20 sessions over 4 weeks improved social functioning and sleep. These findings suggest that transcranial pulsed current stimulation may serve as a viable nonpharmacologic alternative for autism spectrum disorder. Corresponding Author: To contact the corresponding author, Zhenhuan Liu, MD, PhD, email lzh1958424@163.com. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.5776) Editor’s ...

Hospitalized patients who receive alcohol use disorder treatment can substantially reduce heavy drinking

2025-04-21
EMBARGOED UNTIL 11 a.m. on Monday, April 21, 2025 Contact: Jillian McKoy, jpmckoy@bu.edu  Michael Saunders, msaunder@bu.edu  ##  Nearly 30 million adults in the United States experience alcohol use disorder (AUD), but the vast majority of people with this condition do not receive treatment. A new study led by Boston University School of Public Health (BUSPH), BU Chobanian & Avedisian School of Medicine, and Boston Medical Center (BMC) researchers indicates that hospitals may be an ideal setting to close this gap in care.  Published in JAMA Internal Medicine, the study found that hospitalized patients with alcohol use ...

MSU to create first-of-its-kind database for analyzing human remains

2025-04-21
MSU has a satellite uplink/LTN TV studio and Comrex line for radio interviews upon request. Images and b-roll EAST LANSING, Mich. – When a medical examiner needs help identifying a deceased person and determining how that person died, they turn to forensic anthropologists. To aid in the identification of unknown human remains, forensic anthropologists are often called upon to create a biological profile, or an estimation of the unknown individual’s age, biological sex, social race (or ancestry) and stature. If you’ve watched the TV show, “Bones,” in which the FBI teams ...

Natural supplement may decrease biological aging and improve muscle strength

2025-04-21
“Our findings suggest that the Cel System supplement range may effectively reduce biological age and improve health metrics, warranting further investigation into its mechanistic pathways and long-term efficacy.” BUFFALO, NY — April 21, 2025 — A new research paper was published in Aging (Aging-US) Volume 17, Issue 3, on March 14, 2025, titled “Effects of a natural ingredients-based intervention targeting the hallmarks of aging on epigenetic clocks, physical function, and body composition: a single-arm ...

Ursolic acid modulates estrogen conversion to relieve inflammation in metabolic dysfunction-associated steatotic liver disease via HSD17B14

2025-04-21
Background and Aims The incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) has been escalating annually, positioning it as the leading cause of chronic liver disease worldwide. Ursolic acid has demonstrated promising therapeutic efficacy in managing MASLD, thereby justifying the need for an in-depth exploration of its pharmacological mechanisms. This study aimed to investigate elucidate the therapeutic mechanisms by which ursolic acid modulates estrogen conversion in the treatment of MASLD. Methods Building upon prior studies that ...

New research highlights how parental awe and pride enhance well-being

2025-04-21
New research from the University of Rochester suggests that experiencing feelings of pride and awe toward one's children can significantly enhance parental well-being. The study, which will be published in the journal Social Psychological and Personality Science, found that these positive emotions contribute to greater life satisfaction and stronger parent-child bonds.  The research team, led by Princeton Chee, conducted a series of studies involving nearly 900 parents to examine how parental pride and awe affect various aspects of well-being.  "Parental pride and awe are common and beneficial feelings parents can have with their ...

Protecting audio privacy at the source

2025-04-21
Sound is a powerful source of information. By training algorithms to identify distinct sound signatures, sound can reveal what a person is doing, whether it's cooking, vacuuming or washing the dishes. And while it's valuable in some contexts, using sound to identify activities comes with privacy concerns, since microphones can reveal sensitive information. To allow audio sensing without compromising privacy, researchers at Carnegie Mellon University developed an on-device filter, called Kirigami, that can detect and delete human speech segments ...

Omnivorous? Vegan? Makes no difference to muscle building after weight training, study finds

2025-04-21
CHAMPAIGN, Ill. — A new study asked three questions about muscle protein synthesis in response to a nine-day diet and weight training regimen: First, does the source of protein — plant or animal-based — make any difference to muscle gain? Second, does it matter if total daily protein intake is evenly distributed throughout the day? And third, does a moderate but sufficient daily protein intake influence any of these variables? The answer to all three questions is “no,” the researchers found. Their findings are reported in the journal Medicine and Science in Sports and Exercise. “The longstanding belief or ...

More ticks carry Lyme disease bacteria in pheasant-release areas

2025-04-21
Ticks are more likely to carry the bacteria that can cause Lyme disease in areas where pheasants are released, new research shows. Pheasants are not native to the UK, but about 47 million are released here each year for recreational shooting. Researchers studied ticks in 25 woodland areas in South West England where pheasants are released – and 25 nearby control sites where no pheasants are released. They found that Borrelia spp. – the bacteria that can cause Lyme disease – was almost ...

Older adults respond well to immunotherapy despite age-related immune system differences

2025-04-21
Older adults with cancer respond just as well as younger patients to immune checkpoint inhibitors despite age-related immune system differences, according to a study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy, and the Johns Hopkins Convergence Institute. The study was supported in part by the National Institutes of Health, including the National Cancer Institute’s Specialized Programs of Research Excellence. Most new solid tumor cancer diagnoses happen in people ages 65 or older, and overall, these patients have worse cancer treatment outcomes than ...

Study reveals new genetic mechanism behind autism development

2025-04-21
Scientists from The Hospital for Sick Children (SickKids) and University of Las Vegas Nevada (UNLV) have uncovered a genetic link between autism spectrum disorder (ASD) and a rare genetic condition called myotonic dystrophy type 1 (DM1). The study, published today in Nature Neuroscience, suggests that while ASD has previously been characterized by a loss of gene function, another mechanism may be leading to the social behaviours often observed in individuals with ASD.  DM1 is an inherited condition which causes progressive muscle ...

The puberty talk: Parents split on right age to talk about body changes with kids

2025-04-21
ANN ARBOR, Mich. –  Most parents agree that talking to their kids about puberty is important—but when and how to start the conversation is often less clear, a new national poll suggests. Among the most common challenges for parents: choosing the right age to start talking about body changes and whether to explain sex, according to the University of Michigan Health C.S. Mott Children’s Hospital National Poll on Children’s Health. Parents are evenly split in thinking it’s best to start talking about puberty before 10 years, at age 10 or when children are older. “It’s easy to assume a child is too ...

Tusi (a mixture of ketamine and other drugs) is on the rise among NYC nightclub attendees

2025-04-21
“Tusi”, also known as “tucibí” or “pink cocaine”, is a drug concoction that emerged in Latin America and Europe within the past decade and is becoming increasingly popular in the USA.  A new study published in the scientific journal Addiction estimates that in 2024, 2.7% of electronic dance music-nightclub attending adults in New York City (NYC) used Tusi in the past year, with higher use among Hispanic people and people who use other drugs.   Consumers often don’t understand what Tusi is when they take it.  Tusi ...

Father’s mental health can impact children for years

2025-04-19
In popular culture, dads are stoic, sensitive and strong. So powerful is the mystique of the happy dad that celebrities, joke books – even hard seltzers – carry the label.   Real life is different. Fathers get down, sometimes debilitatingly. And as new research from Rutgers Health reveals, when paternal depression goes undiagnosed or unaddressed, the negative social and behavioral effects on children can persist for years.   In a study published in the American Journal of Preventive Medicine, Kristine Schmitz, an assistant professor of pediatrics ...

Scientists can tell healthy and cancerous cells apart by how they move

2025-04-19
Tokyo, Japan – Researchers from Tokyo Metropolitan University have found that the motion of unlabeled cells can be used to tell whether they are cancerous or healthy. They observed malignant fibrosarcoma cells and healthy fibroblasts on a dish and found that tracking and analysis of their paths can be used to differentiate them with up to 94% accuracy. Beyond diagnosis, their technique may also shed light on cell motility related functions, like tissue healing.   While scientists and medical experts have been looking at cells under the microscope for many centuries, most studies and diagnoses focus on their shape, what they contain, and where different parts are located inside. ...
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