Researchers have uncovered and then overcome an obstacle that has led to the failure of pioneering efforts in xenotransplantation, in which an animal kidney is transplanted into a human.  More than 800,000 Americans have late-stage kidney disease yet only 3% receive a transplant each year, according to the U.S. Centers for Disease Control and Prevention. To boost the supply of available organs, experts are exploring the use of genetically modified pig kidneys. The genetic changes are meant to keep the human ...

Platelets are small, disc-shaped cell fragments in the blood that are essential to stop bleeding and to initiate blood clotting after injury. Platelet transfusions in patients with severe trauma or medical conditions, including bone marrow disease, leukemia, or sepsis, can be lifesaving. Despite being a standard clinical practice, platelet transfusions face issues related to the availability of blood donations from which platelets are isolated, the relatively short shelf life of purified platelets, and the risk of an immune response in patients receiving platelets from unmatched donors. A potential solution to this has been proposed ...

About The Study: The current analysis illustrates that drug promotion content is frequently posted by individual creators, lacks essential risk information, and bears the hallmarks of undisclosed marketing. These findings suggest that posts circumvented established advertising principles and potentially eroded the fair balance crucial for informed patient decision-making, consistent with prior literature on traditional direct-to-consumer advertising’s impact on prescribing. Corresponding Author: To contact the corresponding author, Alex Kresovich, PhD, email kresovich-alex@norc.org. To access the embargoed ...

About The Study: In this study, higher ultraprocessed food intake was associated with increased risk of early-onset colorectal conventional adenomas. These data highlight the important role of ultraprocessed foods in early-onset colorectal tumorigenesis and support improving dietary quality as a strategy to mitigate the increasing burden of early-onset colorectal cancer.  Corresponding Author: To contact the corresponding author, Andrew T. Chan, MD, MPH, email achan@mgh.harvard.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaoncol.2025.4777) Editor’s Note: Please see the ...

Thoughtful electronic health record system design can nudge physicians toward evidence-based, less invasive treatments Doctors offered two or more treatment alternatives were significantly more likely to choose a better option (62%) than those offered only one (44%) ‘We’re trying to make it easier for physicians to do the right thing’ CHICAGO --- Having more options is always better — until it’s not.  Doctors face this paradox daily when choosing treatment plans for patients, especially under the pressure of packed clinical schedules. Too few choices can limit care, but too many can lead to decision ...

Colorectal cancer used to be associated with old age, but diagnoses have become increasingly common in adults aged 50 or younger particularly in high-income countries like the United States. The reason for this trend is unclear, but a new study led by Mass General Brigham researchers, as part of the Cancer Grand Challenges PROSPECT team, suggests an important link to ultra-processed foods that merits closer investigation. By analyzing the diets and endoscopy results from almost 30,000 women, the team ...

Pinned between the stomach and spine, the pancreas supervises both digestion and blood sugar in the body. It’s also the site of an aggressive cancer called pancreatic ductal adenocarcinoma, or PDAC.  PDAC is the most common type of pancreatic cancer, the third-leading cause of cancer deaths in the U.S. It’s difficult to detect and recurs about 70% of the time after treatment. Only 13% of those diagnosed survive more than five years.  A team of surgeons, anesthesiologists and engineers at the University of ...

Taking a page from market research tactics, UC San Francisco experts are studying whether artificial intelligence (AI) can improve diagnosis of a complex liver condition by using the clinical notes of multiple providers.    Their recent study, published in Gastro Hep Advances, focused on hepatorenal syndrome (HRS), a complex condition associated with liver disease that is often difficult to diagnose during hospitalization. The researchers sought to learn if large language models could analyze the clinical notes of multiple physicians and other providers to improve ...

University of Virginia School of Medicine researchers have identified the first death caused by what is commonly called the “meat allergy” being spread by ticks. A healthy 47-year-old man from New Jersey died abruptly four hours after consuming beef. The cause of his death had been a mystery until UVA Health’s Thomas Platts-Mills, MD, PhD, investigated. A world-renowned allergist, Platts-Mills discovered the allergy and remains the foremost expert on it. The allergy is caused by the bite of the Lone Star tick. Bites can sensitize people to alpha-gal, a sugar found in mammalian meat. People who become sensitized to the sugar can have allergic symptoms such as rash, nausea ...

Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disorder globally, with a rising incidence linked to metabolic syndrome. Its pathogenesis involves a complex interplay of lipid metabolic dysregulation, insulin resistance, oxidative stress, chronic inflammation, and gut-liver axis disruption. Despite recent advances such as Resmethron for advanced metabolic-associated steatohepatitis (MASH), early-stage interventions remain limited. This ...

“This review synthesizes current evidence to inform clinical decision-making and outlines future directions for durable, personalized lymphoma care.” BUFFALO, NY — November 13, 2025 — A new review was published in Volume 12 of Oncoscience on October 13, 2025, titled “Targeted therapies and resistance mechanisms in lymphoma: Current landscape and emerging solutions.” In this article by Bishal Tiwari, Roshan Afshan and Shruthi Sridhar, from Nassau University Medical Center and Detroit Medical Center Wayne State University, researchers reviewed the latest scientific ...

Stories describing what can happen when science is manipulated or misapplied are among the winners of the 2025 AAAS Kavli Science Journalism Awards. Winning journalists also did stories on science at its best, revealing new understanding about the natural world. Independent panels of science journalists select the winners of the awards, which are administered by the American Association for the Advancement of Science (AAAS) and endowed by The Kavli Foundation. There is a Gold Award ($5,000) and Silver Award ($3,500) for each of the eight categories. The global awards program drew entries from 67 countries this year, and 55 percent of the ...

Well-being and school results are inter-connected, but some children simply do not enjoy school. So what can we do to make school a happier experience for more children? Professor Hermundur Sigmundsson works at the Norwegian University of Science and Technology (NTNU’s) Department of Psychology and has spent many years conducting research on learning and schooling. He and his colleagues are currently carrying out a project in Vestmannaeyjar in Iceland. Among other things, they have investigated ...

A blocked coronary artery causing an acute heart attack must be opened immediately with a stent procedure. However, if other coronary arteries also appear to be narrowed, it is safe to wait and treat those later. This approach cuts the number of stent procedures in half, according to cardiologists from Radboud university medical center, writing in The New England Journal of Medicine. Each year, 33,600 people are admitted to the hospital with a heart attack. In those cases, doctors must quickly open the blocked artery with angioplasty to prevent part of the heart muscle from dying. Yet during the procedure, it often becomes ...

Peer-reviewed. Literature Review. Ecology.  University of Leeds news    Efforts to join up isolated plant and animal habitats across the world should also protect against unintentionally harming them, new research shows.   The paper, led by the Universities of Leeds and Oxford and published today in Nature Reviews Biodiversity journal, states that work to connect fragmented wildlife habitats is essential - but it may also pose ecological risks including the unintentional spread of wildlife diseases and invasive species.  Wildlife or ecological corridors ...

For decades, Lyme disease has frustrated both physicians and patients alike. Caused by the corkscrew-shaped bacterium Borrelia burgdorferi, the infection, if left untreated, can linger for months, leading to fever, fatigue and painful inflammation. In a new study, Northwestern University and Uniformed Services University (USU) scientists have uncovered a surprising — and ironic — vulnerability in the hardy bacterium. By exploiting this vulnerability, researchers could help disarm B. burgdorferi, potentially leading to new therapeutic strategies for Lyme disease. The Northwestern and USU team discovered ...

Florida’s beaches – particularly those in Palm Beach County – are among the world’s most vital nesting grounds for loggerhead sea turtles (Caretta caretta), accounting for 90% of all loggerhead nests in the Southeastern United States. Where a sea turtle chooses to nest is a delicate balance between the energy spent searching for the right spot and the benefits that location provides for successful egg incubation. Because nest placement directly influences hatchling survival, emergence success, and even sex ratios, ...

LOS ANGELES — City of Hope® Research Spotlight offers a glimpse into groundbreaking scientific and clinical discoveries advancing lifesaving cures for patients with cancer, diabetes and other chronic, life-threatening diseases. Each spotlight features research-related news, such as recognitions, collaborations and the latest research defining the future of medical treatment.  To learn more about research at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation’s top cancer centers by U.S. News & World Report, visit our newsroom.    Long-Term ...

The lithium-ion battery is a new energy storage device widely employed in various fields such as mobile power, electric vehicles, unmanned aerial vehicles, and spacecrafts due to its high energy, high efficiency, lightweight, and environmental friendliness. Understanding the internal mechanism of the battery is of utmost importance. The electrochemical model provides detailed insights into the internal mechanism of lithium batteries and encompasses the single-particle model and the P2D model, as well as ...

SEATTLE, WASH. —NOVEMBER 13, 2025— Imagine if every neuroscientist in the world could suddenly speak the same language and share their discoveries instantly.  Allen Institute researchers and engineers have now unlocked that potential and the vast discoveries it could lead to through the new Brain Knowledge Platform (BKP).    This first-of-its-kind database and research tool has just launched with data from over 34 million brain cells. It compiles and standardizes the world’s neuroscience data into a common format and language allowing deep, seamless collaboration between international ...

BETHESDA, MD – November 13, 2025 | The American College of Medical Genetics and Genomics (ACMG) announced today that Melanie Wells, MPH, CAE, Chief Executive Officer of ACMG and the ACMG Foundation for Genetic and Genomic Medicine (ACMGF), will step down from her role, concluding her tenure on November 21, 2025. Wells will continue to support the organizations through the transition period, and ACMG and ACMGF will appoint an interim CEO shortly to ensure continuity of leadership and operations. Wells joined the organizations in 2016 and has served in multiple leadership capacities, ...

In the hushed light of a museum gallery, Hallie Meredith discovered something intriguing about ancient Roman glasswork hiding in plain sight. It was February 2023, and the Washington State University art history professor and glassblower was examining a private collection of Roman glass cage cups at the Metropolitan Museum of Art in New York City. These delicate works of luxury were carved from a single block of glass between 300 and 500 CE and have been studied for centuries for their beauty. Meredith’s revelation was not the result of advanced imaging or new technology but rather a simple act of curiosity: turning one of the vessels around. On the reverse side ...

Supported catalysts are systems in which the active catalytic materials, such as metals, are dispersed on a solid support material, such as alumina, silica, etc. These catalysts are widely used in various chemical processes. Several methods are available for preparing supported catalysts. Among these, the simple impregnation method is particularly suited for industrial settings. In this method, metal precursors and oxide supports are mixed, dried, and crystallized via heat treatment under certain gases. Various high-performance supported catalysts have been prepared using impregnation. However, this method has mostly been used to synthesize conventional monometallic ...

“Shaken, not stirred” — it is widely known how James Bond prefers his martinis. In physics, stirring stretches a fluid into thin streaks, creating turbulence and mixing its properties. In the ocean, a similar process occurs as winds and other forces move seawater. When this happens horizontally over tens to hundreds of kilometres, it is called mesoscale horizontal stirring (MHS). MHS plays a crucial role in redistributing heat, nutrients, and dissolved substances in the upper ocean, shaping plankton distribution and influencing ...

In an era driven by complex data, scientists are increasingly encountering information that doesn’t lie neatly on flat, Euclidean surfaces. From 3D medical scans to robot orientations and AI transformations, much of today’s data lives on curved geometric spaces, called Riemannian manifolds. Analyzing such data accurately has remained a challenge, especially when noise or outliers distort results. To address this, Professor Jongmin Lee from the Department of Statistics, Pusan National University in collaboration with Professor Sungkyu Jung of Seoul National University developed a new statistical method called the ...