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Newly discovered PNS microglia found to regulate neuron size

2025-04-07
In a study published in Cell on April 7, a research team led by Prof. LI Hanjie from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has revealed the presence of microglia in the peripheral nervous system (PNS) and identified their crucial role in regulating neuronal soma size throughout evolution. Microglia, also known as macrophages of the central nervous system (CNS), are specialized immune cells vital for brain health and injury response. ...

Brain’s own repair mechanism: New neurons may reverse damage in Huntington’s disease

Brain’s own repair mechanism: New neurons may reverse damage in Huntington’s disease
2025-04-07
New research shows that the adult brain can generate new neurons that integrate into key motor circuits. The findings demonstrate that stimulating natural brain processes may help repair damaged neural networks in Huntington’s and other diseases.   “Our research shows that we can encourage the brain’s own cells to grow new neurons that join in naturally with the circuits controlling movement,” said Abdellatif Benraiss, PhD, a senior author of the study, which appears in the journal Cell Reports. “This discovery offers a potential new way to restore brain function and slow the progression ...

Neighborhood disadvantage, individual experiences of racism, and breast cancer survival

2025-04-07
About The Study: In this cohort of Black women, living in disadvantaged neighborhoods was associated with a higher mortality from breast cancer, even after accounting for stage at diagnosis, treatments, and individual-level lifestyle factors. Community-level interventions to reduce environmental stressors and improve conditions in disadvantaged neighborhoods, including access to high-quality cancer care, may be critical to reducing racial disparities in breast cancer survival. Corresponding Author: To contact the corresponding author, Etienne X. Holder, PhD, MPH, email exholder@bu.edu. To access the embargoed study: ...

Cardioprotective glucose-lowering agents and dementia risk

2025-04-07
About The Study: While cardioprotective glucose-lowering therapies were not associated with an overall reduction in all-cause dementia, this meta-analysis of randomized clinical trials found that glucose lowering with glucagon-like peptide-1 receptor agonists (GLP-1RAs) was associated with a statistically significant reduction in all-cause dementia. Corresponding Author: To contact the corresponding author, Catriona Reddin, MD, email reddin.catriona@gmail.com. To access the embargoed study: ...

Two-thirds of U.S. adolescent minors are impacted by state abortion restrictions

2025-04-07
More than 7 million American adolescent girls ages 13 to 17 live in states with abortion bans, restrictive gestational limits or parental involvement requirements, according to Rutgers Health researchers.   Their study, published in JAMA Pediatrics, is the first to examine in detail the experiences of adolescent girls after states enacted restrictions on abortion access following the 2022 Dobbs v. Jackson Women’s Health Organization Supreme Court decision.   “As a result of Dobbs, two-thirds of girls ages 13 to 17 now live in states that ban or severely restrict their abortion ...

GLP-1RA and SGLT2i medications for type 2 diabetes and Alzheimer disease and related dementias

2025-04-07
About The Study: In people with type 2 diabetes, both glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2is) were statistically significantly associated with decreased risk of Alzheimer disease and related dementias compared with other glucose-lowering drugs, and no difference was observed between both drugs. Corresponding Author: To contact the corresponding author, Jingchuan Guo, MD, PhD, email guoj1@ufl.edu. To access the embargoed study: Visit our For The Media website at this ...

In the search for life on exoplanets, finding nothing is something too

In the search for life on exoplanets, finding nothing is something too
2025-04-07
What if humanity's search for life on other planets returns no hits? A team of researchers led by Dr. Daniel Angerhausen, a Physicist in Professor Sascha Quanz's Exoplanets and Habitability Group at ETH Zurich and a SETI Institute affiliate, tackled this question by considering what could be learned about life in the universe if future surveys detect no signs of life on other planets. The study, which has just been published in The Astronomical Journal and was carried out within the framework of the Swiss National Centre of Competence in Research, PlanetS, relies on a Bayesian statistical analysis to establish the minimum number of exoplanets that should ...

Molecules that fight infection also act on the brain, inducing anxiety or sociability

2025-04-07
CAMBRIDGE, MA -- Immune molecules called cytokines play important roles in the body’s defense against infection, helping to control inflammation and coordinating the responses of other immune cells. A growing body of evidence suggests that some of these molecules also influence the brain, leading to behavioral changes during illness. Two new studies from MIT and Harvard Medical School, focused on a cytokine called IL-17, now add to that evidence. The researchers found that IL-17 acts on two distinct brain regions — the amygdala and the somatosensory cortex — to exert two divergent effects. In the amygdala, IL-17 can elicit feelings of anxiety, while in the cortex it promotes ...

Home care cooperatives may be key to addressing the critical shortage of caregivers for the elderly

2025-04-07
Home care cooperatives may be the key to alleviating the shortage of paid caregivers for older Americans, a new study suggests. The research, to be published in the peer-reviewed journal JAMA Network Open, found that participants in cooperatives experienced more respect, control, job support, and compensation than their counterparts in traditional care services. These factors may explain how cooperatives have achieved half the turnover rates of traditional agencies, which are plagued with high turnover and employee dissatisfaction. Millions of older adults will lack the support they need to safely age at home unless new strategies are developed and policies are ...

Researchers have a proven prescription for reducing suicide rates

2025-04-07
DETROIT (April 7, 025)— Nearly every person who dies by suicide visits a doctor’s office within a year of their death. A new body of research suggests that by adopting a specific protocol, health systems can reduce suicide rates among those patients by 25%. Researchers say the findings support comprehensive widespread adoption of a method audaciously named The Zero Suicide (ZS) Model, as suicide remains among the leading causes of death in the U.S. In 2022, 49,000 people died by suicide in the U.S. Suicide was the second ...

What if we find nothing in our search for life beyond Earth?

What if we find nothing in our search for life beyond Earth?
2025-04-07
April 7, 2025, Mountain View, CA --  What if we spend decades building advanced telescopes to search for life on other planets and come up emptyhanded? A recent study led by ETH Zurich researchers including corresponding author and SETI Institute affiliate, Dr. Daniel Angerhausen, tackled this question, exploring what we can learn about life in the universe—even if we don’t detect signs of life or habitability. Using advanced statistical modeling, the research team sought to explore how many exoplanets scientists should observe and understand ...

New findings on T cell exhaustion: The body prepares early for mild to severe disease

New findings on T cell exhaustion: The body prepares early for mild to severe disease
2025-04-07
Even in the case of uncomplicated infections, the body prepares itself early on for the possibility of a more severe course. A research team from the Technical University of Munich (TUM) and Helmholtz Munich has now uncovered this mechanism. The scientists showed that, right at the onset of mild illness, the body also produces special T cells previously known only from chronic, severe infections and tumors. There are different types of T cells in the body, all of which play a crucial role in the immune system. They fight pathogens and control the immune response. However, some subtypes become less effective ...

Howard University football team joins the Nation of Lifesavers

2025-04-07
DALLAS, April 7, 2025 — On Saturday, April 5, the Howard University football team participated in an American Heart Association Hands-Only CPR (cardiopulmonary resuscitation) training to learn the correct rate and depth of CPR compressions to be confident and capable when faced with a cardiac emergency. According to American Heart Association data, 9 out of every 10 of people who experience cardiac arrest outside of a hospital die, in part because they do not receive immediate CPR more than half of ...

Korea University and Yonsei University's Colleges of Medicine promote a joint research project to train new Korean physician-scientists

Korea University and Yonsei Universitys Colleges of Medicine promote a joint research project to train new Korean physician-scientists
2025-04-07
Korea University College of Medicine (Dean Pyun Sung-Bom) and Yonsei University College of Medicine (Dean Choi Jae-Young) are kicking off a step-by-step global R& D network project in earnest to train future domestic physician-scientists.   Both colleges jointly operate the "Physician-scientist Network Expansion and Career Attraction Program" supported by the Ministry of Health and Welfare. At the same time, the colleges plan to promote the training of domestic physician-scientists and ...

Researchers discover way to predict treatment success for parasitic skin disease

Researchers discover way to predict treatment success for parasitic skin disease
2025-04-07
Nearly one million people worldwide are plagued annually by cutaneous  leishmaniasis, a devastating skin infection caused by the Leishmania parasite. Predominantly affecting vulnerable populations in tropical and subtropical regions like North Africa and South America, this disease thrives in areas marked by malnutrition, poor housing and population displacement. Left untreated, it can lead to lifelong scars, debilitating disability and deep social stigma. Despite its global impact, there is no vaccine—and existing treatments are ineffective, toxic and difficult to administer.  A new study published in the journal Nature Communications on April 4, 2025, ...

Journal of Health Communication publishes inaugural Society for Health Communication special issue

Journal of Health Communication publishes inaugural Society for Health Communication special issue
2025-04-07
New York, NY | April 7, 2025  – The Society for Health Communication and the Journal of Health Communication at the CUNY Graduate School of Public Health and Health Policy (CUNY SPH) have published its inaugural special issue: Successes and Failures: Everything We Learned from Health Communication Campaigns and Programs. It includes nine peer-reviewed research papers from health communication programs in the U.S. and around the world, featuring insights ...

‘Ugh, not that song!’ Background music impacts employees

2025-04-07
COLUMBUS, Ohio – Have you ever gone to a store or a restaurant where the music was so annoying that you walked right out? Now imagine what it must be like for the employees.   In a new study, researchers found that when background music at a workplace is out of sync with what workers need to do their jobs, it can affect their energy, mood – and even performance.   “Music that doesn’t fit what an employee needs to feel energized, manage emotions, and focus on task can have a real negative impact,” said Kathleen Keeler, co-lead author of the study and assistant ...

New study finds that 90 percent of U.S. Christian leaders believe climate change is real

New study finds that 90 percent of U.S. Christian leaders believe climate change is real
2025-04-07
Chestnut Hill, Mass (4/7/2025) – From Catholics to Evangelicals, a surprising 90 percent of Christian leaders in the U.S. believe in man-made climate change, yet most do not share that understanding with their congregants, according to a new report by Boston College researchers. The findings hold implications for how Christians might help address climate change, knowing their beliefs about the climate crisis align with their church’s values, according to Boston College Assistant Professor of Psychology Gregg Sparkman, senior author of the ...

Study finds global downturn in bias against stigmatized groups

Study finds global downturn in bias against stigmatized groups
2025-04-07
CHAMPAIGN, Ill. — In a study that tracked explicit and implicit bias against stigmatized groups in 33 countries between 2009 and 2019, researchers found substantial reductions in explicit, self-reported bias against all categories of stigma they examined: age, race, body weight, skin tone and sexual orientation. The picture for implicit bias, which is sometimes described as “hidden” or “automatically revealed” bias, was more varied, however. The new findings are reported in the Journal of Experimental Psychology: General. “We used data from Project Implicit, a website established in the early 2000s that serves both as a venue to educate people ...

Cross-ideological acceptance of illiberal narratives and pro-China propaganda in Japan

Cross-ideological acceptance of illiberal narratives and pro-China propaganda in Japan
2025-04-07
Illiberal pro-China narratives have gained traction in democratic countries like Japan, raising questions about how such narratives spread across political ideologies. Social media has become a key tool in this process, blurring the lines between traditional propagandists and their audiences. Ordinary citizens and astroturfing agents[1] within the target countries are now actively engaged in interpreting and disseminating propaganda, making participatory propaganda increasingly relevant in today’s information landscape. Although ...

AI tool can track effectiveness of multiple sclerosis treatments

2025-04-07
A new artificial intelligence (AI) tool that can help interpret and assess how well treatments are working for patients with multiple sclerosis (MS) has been developed by UCL researchers. AI uses mathematical models to train computers using massive amounts of data to learn and solve problems in ways that can seem human, including to perform complex tasks like image recognition. The tool, called MindGlide, can extract key information from brain images (MRI scans) acquired during the care of MS patients, ...

The new season of The Last of Us has a spore-ting chance at realism

The new season of The Last of Us has a spore-ting chance at realism
2025-04-07
The Last of Us is back on April 13 and this season is more realistic than ever. The trailer for the hit HBO series appears to show the “zombie fungus” cordyceps infecting humans by releasing air-borne spores, instead of through tentacles—closer to scientific reality. Spread the love (and spores) “Fungi love to make spores,” says Dr. Jim Kronstad, a professor and microbiologist at UBC’s Michael Smith Laboratories. Real-life cordyceps colonizes ant brains, causing the insect to climb to a high branch. The fungus then ...

Alternative approach to Lyme disease vaccine development shows promise in pre-clinical models

2025-04-07
Meeting the unmet need for a vaccine is the top priority for researchers studying Lyme disease, which infects about 476,000 people in the U.S. each year and can come with severe complications such as ongoing fatigue and joint issues. Vaccine developers have come close to success, but no human vaccine has yet been commercially viable.   After decades of trial and error, a promising new target is emerging—the Lyme bacterial protein CspZ, which the bacteria use to evade detection from the body’s immune system. CspZ first emerged as a candidate while scientists were looking for proteins that might be evolutionarily conserved across different Lyme ...

Equitable access to digital technologies may help improve cardiovascular health

2025-04-07
Statement Highlights: Mobile health technologies, such as wearable devices, mobile health apps and telehealth or remote coaching, have shown potential to help people start and maintain heart-healthy behaviors, such as eating a healthy diet, increasing physical activity, quitting smoking, monitoring sleep and more. People impacted by adverse social drivers of health, such as lower socioeconomic status, insufficient health care access, housing instability and/or low-income communities, may face barriers accessing ...

Is AI in medicine playing fair?

Is AI in medicine playing fair?
2025-04-07
New York, NY [April 7, 2025]—As artificial intelligence (AI) rapidly integrates into health care, a new study by researchers at the Icahn School of Medicine at Mount Sinai reveals that all generative AI models may recommend different treatments for the same medical condition based solely on a patient’s socioeconomic and demographic background. Their findings, which are detailed in the April 7, 2025 online issue of Nature Medicine [DOI: 10.1038/s41591-025-03626-6], highlight the importance of early detection and intervention to ensure that AI-driven care is safe, effective, and appropriate for all. As ...
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