About The Study: This randomized clinical trial found that this unsupervised multimodal online tai chi intervention improved knee pain and function compared with the control at 12 weeks. This free-to-access web-based intervention offers an effective, safe, accessible, and scalable option for guideline-recommended osteoarthritis exercise.  Corresponding Author: To contact the corresponding author, Kim L. Bennell, PhD, email k.bennell@unimelb.edu.au. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamainternmed.2025.5723) Editor’s ...

New research from the Champalimaud Foundation (CF) reveals how missing just one essential amino acid can change gene expression and the brain’s sensory systems, prompting animals to seek out protein-rich yeast and gut bacteria that help them restore nutritional balance and survive in times of need. Fermented clues Cheese and chocolate might not tempt a fruit fly’s palate, but to a hungry fly short on nutrients, their smell carries a hidden signal. When deprived of certain amino acids – the building blocks of protein – these tiny insects develop a surprisingly refined ...

“These findings uncover a previously unknown role of TRF1 in regulating metabolism.” BUFFALO, NY — October 27, 2025 — A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled “Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles.” In this study led by first author Jessica Louzame Ruano and corresponding author Maria A. Blasco from the Spanish National Cancer Centre (CNIO), researchers ...

(Toronto, October 27, 2025) JMIR Publications invites submissions to a new theme issue in its premier open access journal JMIR Medical Education titled "Bias, Diversity, Inclusion, and Cultural Competence in Medical Education." The open access journal is indexed in MEDLINE, PubMed, PubMed Central, Scopus, DOAJ, and the Emerging Sources Citation Index (Clarivate) and received a Journal Impact Factor of 12.5 according to the latest release of the Journal Citation Reports from Clarivate, 2025. Biases, both conscious and unconscious, significantly impact judgment, decision-making, and ultimately patient care. This call for papers seeks ...

SAN ANTONIO — October 27, 2025 — Southwest Research Institute (SwRI) has received a seven-year, $9.9 million contract from the U.S. Air Force to predict the life of landing gear components for the F-16 Fighting Falcon fleet. SwRI will leverage its aging aircraft expertise to predict when parts need replacement, determine the root causes of failure and recommend improvements to maintenance practices. The contract falls under the Comprehensive Landing Gear Integrity Program, a 20-year, $300 million Indefinite Delivery ...

Contracts written by employers and landlords often result in second parties—employees and tenants—facing unfair terms because these documents contain unreasonable or ambiguous clauses, leaving the second parties vulnerable to unjust expenses or constraints. For example, “Tenant must provide written notice of intent to vacate at a reasonable time”—commonly used phrasing in leases—is ambiguous because “reasonable” is undefined. Also, “Employee agrees not to work for any business in the United States for two years following termination,” often included in employee contracts, is unenforceable because many ...

Self-affirmations – brief exercises in which people reflect on their core values, identity and positive traits – can increase people’s general well-being and make them happier in small but significant ways, according to research published by the American Psychological Association. “Even brief, low-cost self-affirmation exercises can yield significant psychological benefits in terms of enhancing personal and social well-being,” said study author Minhong (Maggie) Wang, PhD, of The University of Hong Kong. “More importantly, these benefits are both immediate and long-lasting.” The ...

DALLAS, October 27, 2025 — The rapidly expanding availability of remote telehealth cardiac health care poses a growing challenge for health care providers to learn how to use new digital tools and resources safely and effectively to treat people living with chronic health conditions. The American Heart Association (Association), a global force changing the future of health for all, just launched its latest professional certification program to help bridge the gap between traditional practice and remote patient monitoring and care, while promoting privacy and compatibility with ...

Earthquakes in the American state of Utah, the Soultz-sous-Forêts region of France or in the Dutch province of Groningen should not be able to occur even if the subsurface has been exploited for decades. This is because the shallow subsurface behaves in such a way that faults there become stronger as soon as they start moving. At least that is what geology textbooks teach us. And so, in theory, it should not be possible for earthquakes to occur. So why do they still occur in such nominally stable subsurfaces? ...

ATLANTA, Oct. 28, 2025 — A groundbreaking study published in the peer-reviewed journal Music and Medicine demonstrates that intraoperative music therapy significantly reduces the amount of propofol and fentanyl required during laparoscopic cholecystectomy performed under general anesthesia. Patients exposed to therapeutic music also experienced smoother awakenings and lower physiological stress, as measured by decreased perioperative cortisol levels. “These findings show that this is more than just simple background music, rather an integration of a novel intervention into anesthetic ...

In a new study, researchers found high levels of ultrashort-chain per- and polyfluoroalkyl substances (PFAS) in blood samples taken from Wilmington, N.C. residents between 2010-2016. Two ultrashort-chain PFAS – perfluoromethoxyacetic acid (PFMOAA) and trifluoracetic acid (TFA) – were detected at high levels in almost every sample. In contrast, GenX – the chemical that jumpstarted public concern about PFAS in the Cape Fear River Basin – was detected in 20% of the samples. The work adds to the body of evidence that short-chain PFAS can accumulate in the ...

COLUMBUS, Ohio – A new study provides the best evidence to date that the connection patterns between various parts of the human brain can tell scientists the specialized functions of each region.   Previous research has shown the relationship between connectivity and brain function for just one or a few functions, such as perception or social interactions.   But this study goes further by providing a “bird’s eye view” of the whole brain and its many functions, said Kelly Hiersche, lead author of the study ...

Air pollution is widely recognized as a public health hazard, but its role in workplace safety is often underestimated. A new study reveals that polluted air can make industrial accidents both more likely and more severe, adding a hidden layer to their human and economic costs. The research—led by Dr. Ning Zhang of Yonsei University in South Korea, in collaboration with Dr. Zaikun Hou of Shandong University and Dr. Huan Chen of the University of Cambridge—was published in Energy Economics on September 18, 2025. Using two decades ...

ALS, also known as Lou Gehrig’s disease, is among the most challenging neurological disorders: relentlessly progressive, universally fatal, and without a cure even after more than a century and a half of research. Despite many advances, a key unanswered question remains—why do motor neurons, the cells that control body movement, degenerate while others are spared? In their new study, Kazuhide Asakawa and colleagues used single-cell–resolution imaging in transparent zebrafish to show that large spinal motor neurons — which generate strong body movements and are most vulnerable in ALS — operate under a constant, intrinsic burden of protein and organelle degradation. ...

Is your ultra-high-definition television really worth it? Do you need a 4K or an 8K screen to get the best viewing experience at home? According to researchers at the University of Cambridge and Meta Reality Labs, the human eye has a resolution limit: in other words, there are only so many pixels the eye can see. Above this limit, a screen is giving our eyes more information than they can detect. To calculate the resolution limit, the researchers conducted a study that measured participants’ ability to detect specific ...

Kyoto, Japan -- Down here on Earth we don't usually notice, but the Sun is frequently ejecting huge masses of plasma into space. These are called coronal mass ejections (CMEs). They often occur together with sudden brightenings called flares, and sometimes extend far enough to disturb Earth's magnetosphere, generating space weather phenomena including auroras or geomagnetic storms, and even damaging power grids on occasion. Scientists believe that when the Sun and the Earth were young, the Sun was so active that these CMEs may have even affected the emergence and evolution of ...

Toyoake, Japan —October 27, 2025— In a groundbreaking study, researchers at Fujita Health University and the Tokyo Metropolitan Institute of Medical Science have uncovered a previously overlooked form of brain abnormality linked to anxiety: excessive maturation and aging in the hippocampus, a state they term "hyper-maturity." Published in Neuropsychopharmacology, the study systematically screened publicly available omics datasets and identified gene expression signatures of hippocampal ...

In the Egyptian Western Desert, where red sandstones and green shales rise above the arid plains of Kharga Oasis, paleontologists have uncovered a fossil that fundamentally reshapes our understanding of crocodile evolution. The new discovery, published in The Zoological Journal of the Linnean Society, was led by a team of Egyptian paleontologists. The newly described species, Wadisuchus kassabi, lived about 80 million years ago and is now recognized as the earliest known member of Dyrosauridae—a group of ancient crocodiles ...

Lawsonia inermis is best known for making henna, a versatile dye that is used to change the color of skin and clothes. Now, researchers from Osaka Metropolitan University have found another use for the pigments extracted from the dye: treating liver disease. Specifically, they could treat liver fibrosis, a disease that causes excess fibrous scar tissue to build up in the liver as a result of chronic liver injury caused by lifestyle choices such as excessive drinking. Patients with liver fibrosis have increased risks of cirrhosis, liver failure, and cancer. Despite 3–4% of the population having the advanced form of the disease, treatment options remain limited. One ...

Precise metrology forms a fundamental basis for advanced science and technology, including bioimaging, semiconductor defects diagnostics, and space telescope observations. However, the sensor technologies used in metrology have so far faced a physical barrier known as "standard quantum limit". A promising alternative to surpass this limit is the distributed quantum sensor-A technology that links multiple spatially separated sensors into a single, large-scale quantum system, thereby enabling highly precise measurements. To date, efforts ...

October 27, 2025 – Organ donation following medical assistance in dying (MAiD), also known as euthanasia, is a relatively new practice both in North America and worldwide. A first comparison of liver transplantation using organs donated after MAiD in Canada has shown good patient survival with outcomes similar to standard donation after circulatory death. The findings from the new study in the Journal of Hepatology, published by Elsevier, highlight that this practice can help to meet the increasing demand for organs by expanding the donor pool, thereby saving more lives. As of 2025, organ donation following ...

Youth opioid use is increasing in Canada, as are related emergency department visits and deaths, yet governments are not providing adequate support to address this public health crisis, argue the authors of a CMAJ (Canadian Medical Association Journal) editorial https://www.cmaj.ca/lookup/doi/10.1503/cmaj.251682. “If this crisis is not properly addressed now, Canada’s health systems will play a part in perpetuating the opioid crisis for decades to come,” write Dr. Shannon Charlebois, medical editor, CMAJ, and Dr. Shawn ...

Efforts to promote safer opioid prescribing in Canada appear to be having an effect, as new research in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.250670  shows a decrease in opioid dispensing between 2018 and 2022. In the early 2000s, use of prescription opioids to treat acute and chronic noncancer pain increased substantially in Canada, and with it came a rise in opioid-related harms. The availability of more opioid products, coupled with aggressive marketing of these drugs, ...

Is expanding hospital inpatient, or bed-based, care a way to help address the overdose crisis? An analysis article in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.240955  describes the RE-AIM framework (Reach, Effectiveness, Adoption, Implementation, and Maintenance), which can help provinces determine whether bed-cased care is effective. British Columbia and Alberta, the two provinces with the highest rate of overdose deaths, are focusing more on bed-based care. British Columbia is considering expanding capacity, and Alberta is planning to ...

Just in time for Halloween, six new bat species have been discovered by researchers from the Royal Ontario Museum (ROM), Field Museum in Chicago, and Lawrence University in Wisconsin. This nocturnal – and slightly spooky – group of mammals is incredibly diverse, and the discovery adds to the thousands of known bat species. Formally described as new species through the examination of physical and genetic characteristics, these six new species from the Philippines are commonly known as tube-nosed bats. “This latest ...