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Co-mentors announced in unique opportunity for PCCM fellows

2024-08-12
Glenview, Illinois – For the second year of the APCCMPD and CHEST Medical Educator Scholar Diversity Fellowship, Tristan Huie, MD, FCCP, and Anna Neumeier, MD, will be co-mentors for 2025. Designed to pair a fellow-in-training with an established medical educator, the unique scholarship was launched in August 2023 by the American College of Chest Physicians (CHEST) and the Association of Pulmonary and Critical Care Medicine Program Directors (APCCMPD) to improve diversity in respiratory care. The program focuses on creating opportunities for fellows at institutions ...

AI poses no existential threat to humanity – new study finds

2024-08-12
ChatGPT and other large language models (LLMs) cannot learn independently or acquire new skills, meaning they pose no existential threat to humanity, according to new research from the University of Bath and the Technical University of Darmstadt in Germany. The study, published today as part of the proceedings of the 62nd Annual Meeting of the Association for Computational Linguistics (ACL 2024) – the premier international conference in natural language processing – reveals that LLMs have a superficial ability to follow instructions and excel at proficiency in language, ...

Routine lab tests are not a reliable way to diagnose long COVID

2024-08-12
A National Institutes of Health (NIH)-supported study has found that routine lab tests may not be useful in making a long COVID diagnosis for people who have symptoms of the condition. The study, part of NIH’s Researching COVID to Enhance Recovery (NIH RECOVER) Initiative and published in the Annals of Internal Medicine, highlights how challenging it can be to identify and diagnose a novel illness such as long COVID.   “Our challenge is to discover biomarkers that can help us quickly and accurately diagnose long ...

Tracking the color of light

Tracking the color of light
2024-08-12
Since the first demonstration of the laser in the 1960s, laser spectroscopy has become an essential tool for studying the detailed structures and dynamics of atoms and molecules. Advances in laser technology have further enhanced its capabilities. There are two main types of laser spectroscopy: frequency comb-based laser spectroscopy and tunable continuous-wave (CW) laser spectroscopy. Comb-based laser spectroscopy enables extremely precise frequency measurements, with an accuracy of up to 18 digits. This remarkable precision led to ...

Common mechanisms underpinning neurodevelopmental disorders and psychiatric diseases

2024-08-12
Recent large-scale epidemiologic studies have increasingly suggested that aberrant brain development and psychiatric disorders may share common mechanisms. The interplay between genetic variants and environmental stress has been shown to significantly impact genome integrity, reshaping brain development. This can result in changes to neural networks, which are linked to neurodevelopmental and psychiatric disorders—areas where many questions remain unresolved. For more information, visit: bit.ly/4ddJSV0 For contributing article to this research topic, visit: bit.ly/4crNG41 Please use the Hot-Topic Code: BMS-CMP-2024-HT-33 ...

Department of Energy announces 2024 Office of Science Distinguished Scientist Fellows and lecture series

Department of Energy announces 2024 Office of Science Distinguished Scientist Fellows and lecture series
2024-08-12
WASHINGTON, D.C. – Four of the nation’s top scientists have each been awarded $1 million in direct funding via the Department of Energy (DOE) Office of Science Distinguished Scientist Fellows program.   The program was established to develop, sustain, and promote scientific and academic excellence in Office of Science (SC) research through collaborations between universities and national laboratories.  The awards, authorized by the America COMPETES act, are bestowed on senior national laboratory scientists. The United States has ...

Mary Bishai named Distinguished Scientist Fellow

Mary Bishai named Distinguished Scientist Fellow
2024-08-12
UPTON, N.Y. — Physicist Mary Bishai of the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory has been named a 2024 DOE Office of Science Distinguished Scientist Fellow. The honor recognizes her “enduring contributions at the intensity frontier of high energy physics in unraveling fundamental properties of neutrinos, extraordinary leadership and service to the particle physics community, and deep commitment to broadening participation through mentoring next generation scientists.” As described in a DOE Office of Science press release issued today, the ...

Can meditation and stretching relieve cramping caused by cirrhosis?

2024-08-12
People suffering from cirrhosis may find some symptom relief from two accessible activities: stretching and meditation.   A study from the University of Michigan compared the two therapies as a means to relieve nocturnal muscle cramps and found both effective.  The resulting paper, “The RELAX randomized controlled trial: Stretching versus meditation for nocturnal muscle cramps,” appeared in Liver International.  The study Two out of every three people with cirrhosis experience muscle cramps at night that wake them from sleep.  Since ...

Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease

Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
2024-08-12
Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists at St. Jude Children’s Research Hospital, the Peter Doherty Institute for Infection and Immunity and other collaborators have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease. Oleoyl-ACP-hydrolase (OLAH) is an enzyme involved in fatty acid metabolism. A study, published today in Cell, shows that OLAH drives severe disease outcomes.   The important role of OLAH in immune response has gone unrecognized for several reasons, including a lack of noticeable expression in healthy ...

Advances in drug delivery carrier microwave-assisted reactions for enhanced therapeutics and diagnostic purposes

2024-08-12
Microwave irradiation technology is emerging as a powerful tool in the fields of organic synthesis, pharmaceuticals, and nanocarrier development. Recently, microwave-assisted reactions have gained significant attention for their effectiveness in synthesizing drug delivery carriers. This technology offers notable advantages, including high yield, shorter reaction times, and improved compound purity, making it a promising approach for developing nanoparticles with enhanced physicochemical properties and bioavailability. For more information, please visit: bit.ly/3SFk4cf For contributing article in this research topic, visit: bit.ly/3WXyoza Use ...

Presence of liquid water most probable explanation for data collected by mars lander

Presence of liquid water most probable explanation for data collected by mars lander
2024-08-12
Data about Mars’ planetary crust gathered from the Mars InSight lander are best explained by the conclusion that the crust has stores of liquid water. Analysis led by Vashan Wright, a geophysicist at UC San Diego’s Scripps Institution of Oceanography, provides the best evidence to date that the planet still has liquid water in addition to that frozen at its poles. If that conclusion is true, it sets the stage for new research considering the planet’s habitability and continuing a search for life that exists on a place other than Earth. The potential presence of liquid water on Mars has tantalized scientists for decades. Water is essential for a habitable planet. “Understanding ...

Scientists find oceans of water on Mars. It's just too deep to tap.

Scientists find oceans of water on Mars. Its just too deep to tap.
2024-08-12
Using seismic activity to probe the interior of Mars, geophysicists have found evidence for a large underground reservoir of liquid water — enough to fill oceans on the planet's surface. The data from NASA's Insight lander allowed the scientists to estimate that the amount of groundwater could cover the entire planet to a depth of between 1 and 2 kilometers, or about a mile. While that’s good news for those tracking the fate of water on the planet after its oceans disappeared more than 3 billion years ago, the reservoir won't be of much use to anyone trying to tap into it to supply a future Mars colony. It's ...

UMass Amherst researchers ID body’s ‘quality control’ regulator for protein folding

UMass Amherst researchers ID body’s ‘quality control’ regulator for protein folding
2024-08-12
AMHERST, Mass. – Anyone who’s tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer’s disease. Fortunately, our bodies have a quality-control system ...

Forest restoration can boost people, nature and climate simultaneously

2024-08-12
Forest restoration can benefit humans, boost biodiversity and help tackle climate change simultaneously, new research suggests. Restoring forests is often seen in terms of “trade-offs” – meaning it often focuses on a specific goal such as capturing carbon, nurturing nature or supporting human livelihoods. The new study, by the universities of Exeter and Oxford, found that restoration plans aimed at a single goal tend not to deliver the others. However, “integrated” plans would deliver over 80% of the benefits in all three areas at once. It also found that ...

Pre-surgical antibody treatment might prevent heart transplant rejection

2024-08-12
A new study from scientists at Cincinnati Children’s suggests there may be a way to further protect transplanted hearts from rejection by preparing the donor organ and the recipient with an anti-inflammatory antibody treatment before surgery occurs. The findings, published online in PNAS, focus on blocking an innate immune response that normally occurs in response to microbial infections. The same response has been shown to drive dangerous inflammation in transplanted hearts. In the new study – in mice -- transplanted hearts functioned for longer periods when the organ recipients ...

Scientists identify genes linked to relapse in the most common form of childhood leukemia

Scientists identify genes linked to relapse in the most common form of childhood leukemia
2024-08-12
Scientists from St. Jude Children’s Research Hospital, Seattle Children’s and the Children’s Oncology Group (COG) have identified novel genetic variations that influence relapse risk in children with standard risk B-cell acute lymphoblastic leukemia (SR B-ALL), the most common childhood cancer. The identification of genomic predictors of relapse in SR B-ALL provides a basis for improved diagnosis, precise tailoring of treatment intensity and potentially the development of novel treatment approaches. The study was published today in the Journal of ...

Local solvation is decisive for fluorescence of biosensors

2024-08-12
At Ruhr University, the groups of Professor Martina Havenith and Professor Sebastian Kruss collaborated for the study, which took place as part of the Cluster of Excellence “Ruhr Explores Solvation”, RESOLV for short. The PhD students Sanjana Nalige and Phillip Galonska made significant contributions. Carbon nanotubes as biosensors Single-walled carbon nanotubes are powerful building blocks for biosensors, as previous studies revealed. Their surface can be chemically tailored with biopolymers or DNA fragments to interact specifically with a certain target molecule. When such molecules bind, the nanotubes change their emission ...

Parents who use humor have better relationships with their children, study finds

2024-08-12
UNIVERSITY PARK, Pa. — They say that laughter is the best medicine, but it could be a good parenting tool too, according to a new study led by researchers from Penn State. In a pilot study, the research team found that most people viewed humor as an effective parenting tool and that a parent or caregiver’s use of humor affected the quality of their relationship with their children. Among those whose parents used humor, the majority viewed their relationship with their parents and the way they were ...

HHMI invests $500 million in AI-driven life sciences research

HHMI invests $500 million in AI-driven life sciences research
2024-08-12
The Howard Hughes Medical Institute today announced AI@HHMI, a $500 million investment over the next 10 years to support artificial intelligence-driven projects in the life sciences. As the largest private biomedical research organization in the United States, HHMI aims to explore the full promise of AI to accelerate scientific discovery at its Janelia Research Campus in Ashburn, Virginia, and at the more than 300 HHMI-affiliated labs. “By bringing human curiosity and artificial intelligence closer together at every phase of experimentation ...

Locked out of banking: Incarceration is associated with decreased bank account ownership

2024-08-12
People who have served time in jail or prison are less likely to have bank accounts after they are released than they were before serving time, which may hinder their long-term financial security, according to new research. “Locked out of banking: The limits of financial inclusion for formerly incarcerated individuals” was authored by Brielle Bryan, an assistant professor of sociology at Rice University and J. Michael Collins, a professor of public affairs and human ecology and the Fetzer Family Chair in Consumer and Personal Finance at the University of Wisconsin-Madison. It ...

Research spotlight: Generative AI “drift” and “nondeterminism” inconsistences are important considerations in healthcare applications

Research spotlight: Generative AI “drift” and “nondeterminism” inconsistences are important considerations in healthcare applications
2024-08-12
Samuel (Sandy) Aronson, ALM, MA, executive director of IT and AI Solutions for Mass General Brigham Personalized Medicine and senior director of IT and AI Solutions for the Accelerator for Clinical Transformation, is the corresponding author of a paper published in NEJM AI that looked at whether generative AI could hold promise for improving scientific literature review of variants in clinical genetic testing. Their findings could have a wide impact beyond this use case.    How would you summarize your study for a lay audience? We tested whether ...

Comprehensive atlas of normal breast cells offers new tool for understanding breast cancer origin

Comprehensive atlas of normal breast cells offers new tool for understanding breast cancer origin
2024-08-12
INDIANAPOLIS — Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have completed the most extensive mapping of healthy breast cells to date. These findings offer an important tool for researchers at IU and beyond to understand how breast cancer develops and the differences in breast tissue among genetic ancestries. Published this month in Nature Medicine, researchers developed a comprehensive atlas of breast tissue cells – including details ...

Huang studying electric distribution system protection – Modeling and testing with real-time digital simulator

2024-08-12
Liling Huang, Associate Professor, Department of Electrical and Computer Engineering Dominion Energy Faculty Fellow, received funding for: “Electric Distribution System Protection - Modeling and Testing with Real-Time Digital Simulator.” Huang will address the complexities of the electric distribution system introduced by Distributed Energy Resources (DERs) through Real-Time Digital Simulator (RTDS) modeling and Hardware-in-the Loop (HIL) simulation to enhance protection system ...

Singh receives funding for AI innovation for economic competitiveness

2024-08-12
JP Singh, Distinguished University Professor, Schar School of Policy and Government, received funding for: “George Mason University Center for AI Innovation for Economic Competitiveness.” He is collaborating on the project with Co-Principal Investigator Amarda Shehu, Associate Vice President of Research, Institute for Digital Innovation, Professor, Computer Science, College of Engineering and Computing (CEC); Jesse Kirkpatrick, Research Associate Professor, Philosophy, College of Humanities and Social Sciences; Acting Director, Institute for Philosophy and Public Policy, Philosophy and Religious Studies; Terry Clower, Northern Virginia Chair in Local ...

Bacteria in lakes fight climate change

Bacteria in lakes fight climate change
2024-08-12
Methane is a potent greenhouse gas frequently produced in the sea and in fresh water. Lakes in particular release large quantities of this climate-killer. Fortunately, however, there are microorganisms that counteract this: They are able to utilize methane to grow and generate energy, thus preventing it from being released into the atmosphere. These microorganisms, known as methanotrophs, are therefore regarded as an important "biological methane filter". Methanotrophs comprise various groups of microorganisms, and many questions about their way of life have yet to be answered. A study by researchers from the Max Planck Institute for ...
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