A new CU Boulder-led study has revealed that recent changes in North Pacific Ocean temperatures—long believed to be the result of natural variability—are in fact being driven by human-generated greenhouse gas and industrial aerosol emissions. These oceanic shifts are directly linked to the prolonged megadrought gripping the American Southwest, and this research published August 13th in Nature suggests it may not ease for another 30 years. “Our results show that the drought and ocean patterns we’re seeing today are not just natural fluctuations—they’re largely driven by human activity,” ...

Zheng-Yi Chen, DPhil, associate scientist at the Eaton-Peabody Laboratories, and Ines and Fredrick Yeatts Chair in Otolaryngology, at Mass Eye and Ear, is the senior and co-corresponding author of a paper published in the Journal of Clinical Investigation, “Single Dose Genome Editing Therapy Rescues Auditory and Vestibular Functions in Adult Mice with DFNA41 Deafness.” Q: How would you summarize your study for a lay audience? This study provides an example of a successful use of gene editing technology to treat a mouse model of human genetic hearing loss. We developed a one-time, gene editing ...

Monell Center Researchers Present Latest Findings at International Meeting On Consumer Sensory Science Coinciding with the 2025 Philadelphia-based conference, Monell - the first independent nonprofit dedicated to smell and taste research - hosts academic, industry partners for visits, collaborations  PHILADELPHIA (Aug 14, 2025) – Scientists from the Monell Chemical Senses Center will present their research at the 16th Pangborn Sensory Science Symposium, “Connecting Senses and Minds,” August 17-21, 2025 ...

NEW YORK — The American Federation for Aging Research (AFAR) has received a five-year renewal award totaling $5,722,435 from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), to continue and expand the Nathan Shock Centers Coordinating Center (NSC3). The NSC3 coordinates the activities of the 8 Nathan Shock Centers (NSC) of Excellence in the Basic Biology of Aging, which provide expert resources to expand basic research into the biology of aging. The NSCs began in 1995 in honor of ...

Scientists have pinpointed brain activity related to inner speech—the silent monologue in people’s heads—and successfully decoded it on command with up to 74% accuracy. Publishing August 14 in the Cell Press journal Cell, their findings could help people who are unable to audibly speak communicate more easily using brain-computer interface (BCI) technologies that begin translating inner thoughts when a participant says a password inside their head.  “This is the first time ...

Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise—and induced great disappointment. While effective at activating the immune system to kill cancer cells in animal models, the drugs had limited impact on patients in clinical trials and caused dangerously systemic inflammatory responses, low platelet counts, and liver toxicity, among other adverse reactions—even at a low dose. But in 2018, the lab of Rockefeller University’s Jeffrey V. Ravetch demonstrated it could engineer an enhanced CD40 ...

Nautiloids—a lineage of ancient, externally-shelled cephalopods that diverged from their octopus and squid relatives over 400 million years ago—once dominated our oceans. Today, this living fossil is restricted to a handful of species in the Southern Indo-Pacific, making it one of the few marine invertebrates listed under CITES appendix II of species in need of protection from over-exploitation.. Although no one had previously investigated sex determination systems in cephalopods, recent research suggested a ZZ/Z0 ...

CAMBRIDGE, MA -- With help from artificial intelligence, MIT researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA). Using generative AI algorithms, the research team designed more than 36 million possible compounds and computationally screened them for antimicrobial properties. The top candidates they discovered are structurally distinct from any existing antibiotics, and they appear to work by novel ...

Alzheimer's disease (AD) is the most common neurodegenerative disease in older people, affecting up to 1 in 20 individuals aged 65 and above. In addition to environmental and lifestyle factors, genetic mutations can predispose an individual to AD and some rare forms of inherited “familial” AD (fAD) are caused by known genetic mutations, with these affected individuals developing AD with high probability and at relatively young age. In most cases, AD is diagnosed at advanced stages, but pathological alterations in brain cells may ...

The human papillomavirus (HPV) can cause six types of cancer.  It’s responsible for almost all cervical cancer cases. HPV now causes the majority of oropharyngeal (throat) cancers. It can also cause anal, vaginal, vulvar and penile cancers.   Yet new analysis from researchers at MUSC Hollings Cancer Center shows that most people are unaware of the connection between HPV and all of these cancers.   That awareness is critical, said lead researcher Kalyani Sonawane, Ph.D., because it informs people’s decisions ...

About The Study: In this cross-sectional study, public awareness about human papillomavirus (HPV), HPV vaccination, and the link between HPV and cancers was overwhelmingly low, particularly in Midwestern and Southern U.S. states. These findings are troubling because these regions have recently seen a marked rise in HPV-associated cancers. Notably, the lack of HPV and HPV vaccine awareness in the Midwest and South is alarming, as a majority of states in these regions have suboptimal HPV vaccination rates. Corresponding Author: To contact the corresponding author, Kalyani Sonawane, PhD, email sonawane@musc.edu. To access the embargoed study: Visit ...

ROCHESTER, Minn. — The immune system is meant to protect the body from infection and disease. But with age, it can become less capable of doing so. However, Mayo Clinic researchers have found that some older people maintain "immune youth" – a new term coined by Mayo researchers to explain a young immune system in someone over age 60. "We are studying why some individuals have a 'fountain of youth' in their immune systems. We want to learn from them," says Cornelia Weyand, M.D., Ph.D., a Mayo Clinic rheumatologist ...

About The Study: The findings of this study suggest that semaglutide was not associated with an increased risk of eye disorders or diabetic retinopathy. Despite the fact that an association between semaglutide treatment and nonarteritic anterior ischemic optic neuropathy (NAION) was found, current evidence remains insufficient to establish definitive conclusions regarding its association with NAION. Further studies with larger sample sizes and adequate evaluation of NAION are warranted ...

ANCHORAGE, Alaska — USGS streamgages show flood conditions are now underway, with live cameras providing real-time views on the USGS HIVIS website. Glacier-caused flooding has become an annual threat since 2011, with record-breaking floods over the past two years that impacted more than 300 homes and threatened public safety. The USGS is working with the City and Borough of Juneau, Alaska Department of Transportation and Public Facilities, and the U.S. Army Corps of Engineers to monitor conditions and provide real-time data on the glacier lake releases. A glacier-dammed lake forms when a glacier blocks the natural drainage of a valley, trapping water that eventually ...

“[…]in a population of adults with a smoking history, frailty and prefrailty are associated with increased respiratory exacerbations and increased risk of death.” BUFFALO, NY — August 14, 2025 — A new research paper was published in Volume 17, Issue 7, of Aging (Aging-US) on July 3, 2025, titled “Frailty associates with respiratory exacerbations and mortality in the COPDGene cohort.” In this study, led by first author Eleanor ...

WASHINGTON — Researchers have developed a high-speed 3D imaging microscope that can capture detailed cell dynamics of an entire small whole organism at once. The ability to image 3D changes in real time over a large field of view could lead to new insights in developmental biology and neuroscience. “Traditional microscopes are constrained by how quickly they can refocus or scan through different depths, which makes it difficult to capture fast, 3D biological processes without distortion ...

NRG Oncology (NRG), a National Cancer Institute (NCI) National Clinical Trials Network (NCTN) group focused on improving outcomes for adult cancers, recently opened a new clinical trial “ARCHER” (NRG-GU015) to study a shorter duration of radiation therapy for patients with muscle invasive bladder cancer. “A quarter of all bladder cancers in the United States are muscle-invasive bladder cancers. Currently, the standard of care treatment for this disease consists of either (1) bladder preservation with transurethral ...

In Associate Professor Jonathan Boreyko’s Nature-Inspired Fluids and Interfaces Lab, Ph.D. student Jack Tapocik watched a disc-shaped chunk of ice resting on an engineered metal surface. As the ice melted, the water formed a puddle beneath. Even after many seconds of melting, the ice disk remained adhered to the engineered surface. At first, Tapocik was tempted to conclude that nothing would happen, but he waited. His patience paid off. After a minute, the ice slingshot across the metal plate he designed, gliding along as if it was ...

SAN FRANCISCO, CA — Today, PLOS Biology announced a new agreement with the Research on Research Institute (RoRI) and the Association for Interdisciplinary Meta-Research and Open Science (AIMOS) to become a partner journal with MetaROR (MetaResearch Open Review), a recently launched platform designed to improve the dissemination and evaluation of meta-research. As part of the agreement, PLOS Biology will formally consider meta-research articles that are peer-reviewed on the MetaROR platform, collaborating with RoRI and AIMOS to improve the transparency of peer review in the field of meta-research. This agreement with MetaROR aligns with PLOS’ mission ...

The management of Helicobacter pylori (H. pylori), a globally prevalent gastric pathogen, has long been centered on its eradication to prevent peptic ulcers, gastric malignancies, and related gastrointestinal complications. However, a newly published meta-analysis in eGastroenterology raises a crucial clinical dilemma: Could the treatment itself, intended to heal, paradoxically increase the risk of reflux oesophagitis (RE)? Led by Prof. Mingxin Zhang and colleagues from Xi'an Medical University and The First Affiliated Hospital of Xi'an Medical University, this comprehensive systematic review and meta-analysis ...

The University of California San Diego's Altman Clinical and Translational Research Institute (ACTRI) has received a seven-year, $80 million Clinical and Translational Science Award (CTSA) from the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health. This prestigious award is the fourth consecutive CTSA awarded to the institute since it was established in 2008 and represents one of the largest federal research grants at the university. "This award underscores the national significance of ACTRI’s work ...

Dr. Ji-Hyung Han’s research team from the Convergence Research Center of Sector Coupling & Integration at the Korea Institute of Energy Research (President Yi, Chang-Keun, hereinafter “KIER”) has developed a high-performance carbon cloth-based electrode that maintains stable performance even under high current conditions. The newly developed electrode is the first seawater electrolysis electrode using a carbon cloth support that has demonstrated successful continuous operation for over 800 hours under high current conditions, highlighting its potential for commercialization. Water electrolysis is an ...

Traditional fossil fuels have low combustion efficiency and serious pollution, and the development of new energy conversion technologies such as wind energy and solar energy is limited by environmental conditions. As an efficient energy conversion device that directly converts chemical energy in fuel into electricity, solid oxide fuel cells (SOFCs) have attracted much attention due to their high efficiency, low emissions and strong fuel adaptability.     Although hydrogen is an ideal fuel for SOFC, its high storage and transportation  limit its large-scale application. Due ...

A recent study from researchers at University of California San Diego is the first detailed assessment of companies offering school-based online surveillance services such as social media monitoring, student communications monitoring and online activity monitoring to middle and high schools. Schools pay for the services directly or may request federal grant funding to cover the costs.  Originally intended to support students’ mental health and prevent adverse school events, such as school shootings, ...

Determining whether a cancerous tumor originated in a given location or spread there from another tissue or organ in the body is important when assessing the likely course of a patient’s disease. When the origin of the primary tumor cannot be identified, it can be challenging to properly diagnose the malignancy and determine the best treatment strategy. Now, researchers at University of California San Diego have identified a microbial DNA signature in blood plasma that reliably differentiates primary liver cancer from colorectal cancer that has spread to the liver (metastatic colorectal cancer). “The use of microbial DNA signatures could open up a new diagnostic pathway, ...