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Tumor blood vessels prevent the spread of cancer cells

2013-02-11
A lack of the protein endoglin in the blood vessels of tumour-bearing mice enables the spread of daughter tumours, according to researchers at Karolinska Institutet and Lund University in Sweden in a study published in the scientific periodical The Journal of Experimental Medicine. Given that the tumour vasculature constitutes an important barrier to the spread of cancer cells, the team suggests that drugs should be developed to strengthen the blood vessels' protective function. Studies of the process of metastasis (the spread of daughter tumours) have mainly focused ...

Earth-directed CME released by long duration solar flare

Earth-directed CME released by long duration solar flare
2013-02-11
On Feb. 9, 2013 at 2:30 a.m. EST, the sun erupted with an Earth-directed coronal mass ejection or CME, associated with a long duration C2.4-class flare. Experimental NASA research models, based on observations from the Solar Terrestrial Relations Observatory (STEREO) and ESA/NASA's Solar and Heliospheric Observatory, show that the CME left the sun at speeds of around 500 miles per second, which is a fairly typical speed for CMEs. Historically, CMEs at this speed are usually benign. Not to be confused with a solar flare, a CME is a solar phenomenon that can send solar ...

CWRU study suggests interacting with avatars may reduce depressive symptoms in young adults

2013-02-11
Young adults, in a period of transition, are often reluctant to seek treatment for mental health problems because of the stigma, inadequate insurance coverage and difficulty finding a mental health care provider. But a new preliminary study by researchers at Case Western Reserve University suggests that depression symptoms may be significantly reduced when 18- to 25-year-olds interact with computerized avatars—virtual 3D images of a healthcare provider like a nurse practitioner or physician —as a way to rehearse office visits ahead of time and learn self-management skills. ...

Researchers find Asian needle ants displacing other aggressive invaders

Researchers find Asian needle ants displacing other aggressive invaders
2013-02-11
Researchers from North Carolina State University have found that one of the most aggressive invasive ant species in the United States – the Argentine ant – appears to have met its match in the Asian needle ant. Specifically, the researchers have found that the Asian needle ant is successfully displacing Argentine ants in an urban environment, indicating that the Asian needle ant – with its venomous sting – may be the next invasive species to see a population boom. In the world of invasive species, the Argentine ant (Linepithema humile) is a success story. Its aggressive, ...

Online or off, bullying proves harmful

Online or off, bullying proves harmful
2013-02-11
EAST LANSING, Mich. — Children who are bullied online or by mobile phone are just as likely to skip school or consider suicide as kids who are physically bullied, according to a study led by a Michigan State University criminologist. The findings, published in the International Criminal Justice Review, suggest parents, school officials and policymakers should consider bullying experiences both on and offline when creating anti-bullying policies and procedures. "We should not ignore one form of bullying for the sake of the other," said Thomas Holt, associate professor ...

Study shows progesterone shots do not reduce preterm delivery in twin pregnancies

2013-02-11
In a study to be presented on February 14 between 8 a.m. and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's 33rd annual meeting, The Pregnancy Meeting ™, researchers will report findings that suggest that 17P, a form of progesterone, is not effective in preventing preterm birth among women with twin pregnancies — and may possibly be harmful. While 17P (17 alpha-hydroxyprogesterone caproate) has been shown to prevent premature delivery among about one-third of women with a singleton pregnancy who have experienced a prior preterm delivery, this latest research ...

Rice University lab shows how blood vessels regroup after stroke

2013-02-11
By thinking of cells as programmable robots, researchers at Rice University hope to someday direct how they grow into the tiny blood vessels that feed the brain and help people regain functions lost to stroke and disease. Rice bioengineer Amina Qutub and her colleagues simulate patterns of microvasculature cell growth and compare the results with real networks grown in their lab. Eventually, they want to develop the ability to control the way these networks develop. The results of a long study are the focus of a new paper in the Journal of Theoretical Biology. "We ...

Presence of intra-amniotic debris a risk for early preterm birth in first pregnancy

2013-02-11
In a study to be presented on February 14 between 8 a.m. and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers will report findings suggesting an increased risk of early (less than 35 weeks) preterm birth when intra-amniotic debris is present in nulliparous women with a short cervix. The babies born to women with debris had worse outcomes than those born to women without debris, likely due to the earlier delivery. The multicenter study, presented by Dr. George Saade for the Eunice ...

Can simple measures of labile soil organic matter predict corn performance?

2013-02-11
Organic matter is important for soil health and crop productivity. While an indicator of soil quality, a lot of organic matter is in extremely stable forms, and the nutrients in such forms are difficult for plants to use. The active, labile fraction, however, is a modest but important part of the organic matter. "The labile fraction is small – usually less than 20 or even 10 percent, depending on how you define it," explains Steve Culman, lead author of a study published online Feb. 8 in Agronomy Journal. "But it is where a lot of the action happens. It's where soil nutrients ...

Study finds planned C-sections provide no advantage over planned vaginal birth of twins

2013-02-11
In a study to be presented on February 14 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest that planned birthing of twins at 32-38 weeks by cesarean section does not decrease perinatal or neonatal death compared to planned vaginal birth. This randomized study The Twin Birth Study: a multicenter RCT of planned cesarean section and planned vaginal birth for twin pregnancies 320 to 386/7 weeks, should help women understand that a planned vaginal ...

Study suggests genetic predisposition to brain injury after preterm birth is sex-specific

2013-02-11
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report that variation in a gene involved in inflammation is associated with developmental problems after preterm birth in females, but not males. This randomized study, Sex-specific genetic susceptibility to adverse neurodevelopmental outcome after early preterm birth, may improve understanding of how developmental problems occur after preterm birth and may help identify ...

Study suggests tightening up of criteria for definition of intrauterine growth restriction

2013-02-11
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report that the practice of using an arbitrary Estimated Fetal Weight (EFW) less than the 10th centile may not be an efficient practice for defining true Intrauterine Growth Restriction (IUGR). The study was conducted by the Perinatal Ireland Research Consortium, a nationwide collaborative research network comprising of the seven largest academic obstetric centers in Ireland. ...

Policy changes in elective delivery proven successful

2013-02-11
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers will present data showing changes in elective delivery policy have been successful in reducing elective deliveries prior to 39 weeks. Due to the troubling trend of elective delivery and induction, significant attention has been paid to the neonatal benefits of reducing elective deliveries before 39 weeks, both on the national and institutional level. Elective delivery ...

Better outcome for frozen embryo replacement vs IVF

2013-02-11
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers will present findings showing perinatal outcomes of frozen/thawed embryo replacement (FER) have better outcomes compared to fresh in vitro fertilization (IVF), but worse outcomes compared to the non-IVF general population. The study collected data from all IVF treatments in Denmark, Norway and Sweden from 1984 – 2007, then cross-linked with the Nordic Medical Birth ...

Preemptive treatment of severe morning sickness decreases suffering for moms-to-be

2013-02-11
`In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers will present data showing the effectiveness of preemptive treatment for hyperemesis gravidarum and severe morning sickness. Hyperemesis gravidarum is a severe form of morning sickness which effects one in 50 pregnant women. HG is marked by persistent nausea and vomiting, and can begin early in the first trimester, continuing well into the second, third or even up ...

Differences in obstetric outcomes and care related to race and ethnicity

2013-02-11
In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers will present data showing racial and ethnic disparities exist for adverse obstetric outcomes. In his study Dr. William Grobman of Northwestern University, presenting for the Eunice Kennedy Shriver National Institute of Child Health and Human Development, studied 115,502 women over a three year period to see if adverse obstetric outcomes and provisions in obstetric ...

Abnormal brain development in fetuses of obese women

2013-02-11
In a study to be presented on February 15 between 8 a.m. and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, California, researchers from Tufts Medical Center will present findings showing the effects of maternal obesity on a fetus, specifically in the development of the brain. The study, conducted at the Mother Infant Research Institute (MIRI) at Tufts Medical Center in Boston, Mass., looked at the fetal development of 16 pregnant women, eight obese and eight lean, to see what effects maternal obesity ...

Obstructive sleep apnea and cardiac symptoms have 31 percent incidence of cardiac dysfunction

2013-02-11
In a study to be presented on February 15 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that women with obstructive sleep apnea (OSA) and cardiac symptoms have a 31 percent incidence of cardiac dysfunction. The use of echocardiograms should be considered in the clinical management of these women. OSA is characterized by abnormal pauses in breathing or instances of abnormally low breathing, during sleep. These pauses can last from at least ten seconds ...

Community health workers help type 2 diabetes care

Community health workers help type 2 diabetes care
2013-02-11
PROVIDENCE, R.I. [Brown University] — Newly published results from a randomized controlled clinical trial in the Pacific U.S. territory of American Samoa add clear evidence for the emerging idea that community health workers can meaningfully improve type 2 diabetes care in medically underserved communities. In the U.S. territory, 21.5 percent of adults have type 2 diabetes. Meanwhile, 58 percent of families are below the U.S. poverty level. The research team, led by public health researchers from Brown and The Miriam Hospital, wanted to test whether four trained local ...

Caloric restriction, exercise help prevent weight gain, other complications in obese women

2013-02-11
In a study to be presented on February 15 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest that consistent physical activity and healthier lifestyle changes beginning in a woman's first trimester can prevent excessive weight gain in obese pregnant women (with a Body Mass Index greater than 30), helping to avoid preterm delivery, hypertension and gestational diabetes. This randomized study, entitled Occurrence of pregnancy complications ...

'Laborist' obstetrical care improves pregnancy outcomes

2013-02-11
In a study to be presented on February 16 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest shifting from a traditional model of obstetrical care to a laborist model improves pregnancy outcomes. The "laborist" concept has been around for nearly a decade. In this model, obstetricians provide 24-hour a day on-site staffing of labor units. While it has been assumed that laborists improve obstetric care, there had been no studies done to test ...

Around-the-clock labor coverage associated with decrease in C-section

2013-02-11
In a study to be presented on February 16 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest around-the-clock labor and delivery coverage decreased the odds of cesarean delivery. The objective of the study was to determine if the implementation of "laborists" to provide around-the-clock coverage of labor and delivery would produce better outcomes. The study compared outcomes in hospitals with around-the-clock coverage versus hospitals whose ...

Comprehensive maternal hemorrhage protocols improve patient safety

2013-02-11
In a study to be presented on February 16 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest comprehensive maternal hemorrhage protocols reduce utilization of blood products and improve patient safety. A study performed at Dignity Health, the fifth largest health care system in the United States with 31 obstetrical units, showed that the implementation of a standardized comprehensive maternal hemorrhage (CHP) protocol directed towards prevention ...

Study confirms recurrence of small-for-gestational-age pregnancies

2013-02-11
In a study to be presented on February 16 between 8 a.m., and 10 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest women whose babies are small-for-gestational-age (SGA) in their first pregnancy have a strongly increased risk for SGA in a second pregnancy. The aim of this study was to assess and describe in detail the incidence of SGA infants and the SGA recurrence rate in general. Additionally, it sought to assess the incidence and recurrence rate of SGA in women ...

Study prompts rethink of how ovaries develop

Study prompts rethink of how ovaries develop
2013-02-11
New research from the University of Adelaide will rewrite the textbooks on how an ovary is formed, as well as providing new insights into women's health and fertility. The study, now published in the journal PLOS ONE, also names a new type of cell that plays a key role in the development of ovaries and ovarian follicles, which are responsible for the production of eggs in women. The discovery is expected to prompt further studies around the world to better understand how ovaries and ovarian follicles develop in female fetuses. This could be critical to treating or ...
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