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A 'nudge' can be the ethical choice

2013-02-05
HOUSTON -- (Feb. 6, 2013) – As patients and physicians share decision-making in choices among treatment options, decision aids such as videos, websites, pamphlets or books are coming to play an important role. However, in some cases, it may be ethical for the decision aids to provide a "nudge" toward a particular option, said researchers from Baylor College of Medicine, the Michael E. DeBakey Veterans Affairs Medical Center and the University of Texas MD Anderson Cancer Center in a report that appears in the journal Health Affairs. In general, decision aids are meant ...

Study highlights important role that patients play in determining outcomes

2013-02-05
EUGENE, Ore. — When it comes to health care, patients with the motivation, knowledge, skills and confidence to manage their own health have better health outcomes and incur fewer health care costs. Those are the findings of a study led by Judith Hibbard, a professor emerita in the Department of Planning, Public Policy and Management at the University of Oregon. Hibbard and co-authors found that patients with the lowest level of "activation"— that is, those most lacking in the skills and confidence to be actively engaged in their health care — had average costs that were ...

Damaged blood vessels loaded with amyloid worsen cognitive impairment in Alzheimer's disease

2013-02-05
NEW YORK (February 4, 2013) -- A team of researchers at Weill Cornell Medical College has discovered that amyloid peptides are harmful to the blood vessels that supply the brain with blood in Alzheimer's disease -- thus accelerating cognitive decline by limiting oxygen-rich blood and nutrients. In their animal studies, the investigators reveal how amyloid-β accumulates in blood vessels and how such accumulation and damage might be ultimately prevented. Their study, published in the Feb. 4 online edition of the Proceedings of the National Academy of Sciences (PNAS), ...

Researchers develop Rx for deafness, impaired balance in mouse model of Usher syndrome

2013-02-05
New Orleans, LA – Jennifer Lentz, PhD, Assistant Professor of Otorhinolaryngology & Biocommunications and a member of the Neuroscience Center of Excellence at LSU Health Sciences Center New Orleans, is the lead author of a paper reporting that hearing and balance can be rescued by a new therapy in a mouse model of Usher syndrome (Usher) that contains the mutation responsible for type 1C Usher. The results provide the first evidence that congenital deafness can be effectively overcome by treatment early in development to correct gene expression. The paper, Rescue of hearing ...

Monogamous birds read partner's food desires

Monogamous birds read partners food desires
2013-02-05
New research shows that male Eurasian Jays in committed relationships are able to share food with their female partner according to her current desire. The behaviour suggests the potential for 'state-attribution' in these birds – the ability to recognise and understand the internal life and psychological states of others. The research was carried out in Professor Nicola Clayton's Comparative Cognition lab at Cambridge University's Department of Psychology, and is published today in the journal PNAS. Researchers tested mated jays and separated males from females. ...

Birds may need a hand to weather climate change

Birds may need a hand to weather climate change
2013-02-05
A new study led by Durham University and BirdLife International, shows that many bird species are likely to suffer under future climate change, and will require enhanced protection of important sites, better management of the wider countryside, and in some of the most extreme cases may need to be physically moved to climatically suitable areas to help them survive. The priority, the researchers say, is for stronger protection and effective management of networks of important sites for conservation which currently support priority species and could offer new habitat for ...

Research suggests meerkat predator-scanning behaviour is altruistic

2013-02-05
VIDEO: In order to spot potential predators, adult meerkats often climb to a higher vantage point or stand on their hind legs. If a predator is detected, they use several different... Click here for more information. In order to spot potential predators, adult meerkats often climb to a higher vantage point or stand on their hind legs. If a predator is detected, they use several different alarm calls to warn the rest of the group. New Cambridge research shows that they are ...

Vitamin C supplements linked to kidney stones

2013-02-05
New research from Karolinska Institutet in Sweden shows that men who take vitamin C supplements regularly run a higher risk of developing kidney stones. The study, which is published in the scientific periodical JAMA Internal Medicine, did not however observe an increased risk between kidney stones and multivitamins – which contain lower concentrations of vitamin C. The research is based on data from a large population-based study of men from Västmanland and Örebro counties, who were monitored for 11 years. A total of 23,355 men were identified who had no history of ...

Injection-free vaccination technique could address global vaccine challenge for HIV, malaria

2013-02-05
Scientists at King's College London have demonstrated the ability to deliver a dried live vaccine to the skin without a traditional needle, and shown for the first time that this technique is powerful enough to enable specialised immune cells in the skin to kick-start the immunising properties of the vaccine. Funded by the Bill & Melinda Gates Foundation and published today in Proceedings of the National Academy of Sciences, researchers say although it is an early study this important technical advance offers a potential solution to the challenges of delivering live ...

Chemical reaction keeps stroke-damaged brain from repairing itself

Chemical reaction keeps stroke-damaged brain from repairing itself
2013-02-05
LA JOLLA, Calif., February 4, 2013 – Nitric oxide, a gaseous molecule produced in the brain, can damage neurons. When the brain produces too much nitric oxide, it contributes to the severity and progression of stroke and neurodegenerative diseases such as Alzheimer's. Researchers at Sanford-Burnham Medical Research Institute recently discovered that nitric oxide not only damages neurons, it also shuts down the brain's repair mechanisms. Their study was published by the Proceedings of the National Academy of Sciences the week of February 4. "In this study, we've uncovered ...

Biodiversity exploration in the 3-D era

Biodiversity exploration in the 3-D era
2013-02-05
Taxonomy – the discipline that defines and names groups of organisms – is a field of science that still employs many of the methods used during the beginnings of the discipline in the 18th century. Despite the increasing use of molecular information to delineate new species, the study of the morphology of specimens remains one of the major tasks of taxonomists. These studies often require first-hand examination of the reference specimens (so-called type material) deposited at museum collections around the globe - a time-consuming and laborious task. To facilitate this ...

New study finds water tubing-related injuries up 250 percent

2013-02-05
Water tubing, a recreational activity in which participants ride an inner tube which is pulled behind a boat by a tow rope, has grown in popularity in recent years. Unfortunately, the number of injuries related to this activity has also increased. According to a new study by researchers at the Center for Injury Research and Policy of The Research Institute at Nationwide Children's Hospital, the annual number of water tubing-related injuries increased 250 percent over the 19-year study period, rising from 2,068 injuries in 1991 to 7,216 injuries in 2009. Given that more ...

Finding the way to memory

2013-02-05
Our ability to learn and form new memories is fully dependent on the brain's ability to be plastic – that is to change and adapt according to new experiences and environments. A new study from the Montreal Neurological Institute – The Neuro, McGill University, reveals that DCC, the receptor for a crucial protein in the nervous system known as netrin, plays a key role in regulating the plasticity of nerve cell connections in the brain. The absence of DCC leads to the type of memory loss experienced by Dr. Brenda Milner's famous subject HM. Although HM's memory loss resulted ...

February 2013 story tips from Oak Ridge National Laboratory

2013-02-05
HEALTH – Neutron imaging breast cancer . . . More precise optical imaging is vital for better diagnosis of breast cancer, which strikes one in eight women annually in the United States alone. Researchers at Oak Ridge National Laboratory and the University of Tennessee are using the neutron imaging beam line at ORNL's High Flux Isotope Reactor to evaluate neutron imaging as a powerful new tool for early detection. The study, led by Dr. Maria Cekanova of UT, working with imaging instrument scientist Hassina Bilheux, is using tissue from dogs treated at the UT College of ...

MU scientists build harness for powerful radiation cancer therapy

MU scientists build harness for powerful radiation cancer therapy
2013-02-05
VIDEO: A new discovery might lead to alpha particle therapy for different types of cancer in the near future. Click here for more information. COLUMBIA, Mo. ¬— We've all heard that "it's not wise to use a cannon to kill a mosquito." But what if you could focus the cannon's power to concentrate power into a tiny space? In a new study, University of Missouri researchers have demonstrated the ability to harness powerful radioactive particles and direct them toward small cancer ...

Gene variants found to affect human lifespan

2013-02-05
By broadly comparing the DNA of children to that of elderly people, gene researchers have identified gene variants that influence lifespan, either by raising disease risk or by providing protection from disease. "This research is the first genome-wide, population-based study of copy number variations in children associated with human longevity," said study leader Hakon Hakonarson, M.D., Ph.D., director of the Center for Applied Genomics at The Children's Hospital of Philadelphia. The study appeared Jan. 30 in the open-access journal PLOS ONE. Copy number variations ...

1990s drop in NYC crime not due to CompStat, misdemeanor arrests, study finds

2013-02-05
New York City experienced a historic decline in crime rates during the 1990s, but it was not due to the implementation of CompStat or enhanced enforcement of misdemeanor offenses, according to an analysis by New York University sociologist David Greenberg. The study, which appears in the journal Justice Quarterly, did not find a link between arrests on misdemeanor charges and drops in felonies, such as homicides, robberies, and assaults. In addition, the analysis revealed no significant drop in violent or property crime attributable to the NYPD's introduction of CompStat ...

How plants sense gravity -- a new look at the roles of genetics and the cytoskeleton

How plants sense gravity -- a new look at the roles of genetics and the cytoskeleton
2013-02-05
Gravity affects the ecology and evolution of every living organism. In plants, the general response to gravity is well known: their roots respond positively, growing down, into the soil, and their stems respond negatively, growing upward, to reach the sunlight. But how do plants sense gravity and how do they direct or signal their cells to grow in response to it? Although botanists understand a great deal about how this works, a recent article in the recent issue of the American Journal of Botany reviews what we know so far, from mechanical to genetic approaches; it reveals ...

Some cancer mutations slow tumor growth

2013-02-05
CAMBRIDGE, MA -- A typical cancer cell has thousands of mutations scattered throughout its genome and hundreds of mutated genes. However, only a handful of those genes, known as drivers, are responsible for cancerous traits such as uncontrolled growth. Cancer biologists have largely ignored the other mutations, believing they had little or no impact on cancer progression. But a new study from MIT, Harvard University, the Broad Institute and Brigham and Women's Hospital reveals, for the first time, that these so-called passenger mutations are not just along for the ride. ...

Early breast cancer diagnosis, survival rates low in rural India

2013-02-05
ANN ARBOR—Women in developed countries survive roughly 10 years longer after a breast cancer diagnosis compared to women in poor-to-middle-income countries, a new University of Michigan study suggests. The report demonstrates the lack of access to good health care faced by women in poor countries, said the study's principal investigator Rajesh Balkrishnan, an associate professor at the U-M schools of Pharmacy and Public Health. Early diagnosis and sustained treatment were the biggest hurdles and also the main indicators of patient survival, he said. Balkrishnan and ...

Imaging biomarker predicts response to rapid antidepressant

Imaging biomarker predicts response to rapid antidepressant
2013-02-05
VIDEO: NIMH's Dr. Maura Furey talks about how a functional brain imaging measure may help predict a patient's response to a rapid-acting experimental antidepressant. Click here for more information. A telltale boost of activity at the back of the brain while processing emotional information predicted whether depressed patients would respond to an experimental rapid-acting antidepressant, a National Institutes of Health study has found. "We have discovered a potential ...

Children with autism at significant risk for feeding problems and nutritional deficits

2013-02-05
Healthy eating not only promotes growth and development, but also provides important opportunities for children to socialize during meals. A new, comprehensive analysis of feeding behavior in children with autism spectrum disorders (ASD) indicates that these children are five times more likely to have a feeding problem, including extreme tantrums during meals, severe food selectivity and ritualistic mealtime behaviors. Researchers at Marcus Autism Center and the Department of Pediatrics at Emory University School of Medicine conducted a comprehensive meta-analysis of ...

NOAA: Tortugas marine reserve yields more, larger fish

2013-02-05
A new NOAA research report finds that both fish populations and commercial and recreational anglers have benefited from "no-take" protections in the Tortugas Ecological Reserve in the Florida Keys National Marine Sanctuary. The report, "An Integrated Biogeographic Assessment of Reef Fish Populations and Fisheries in Dry Tortugas: Effects of No-take Reserves," is the first to evaluate how the 151-square nautical mile Tortugas Ecological Reserve affects the living marine resources of the region and the people whose livelihoods are connected to them. The report's analysis ...

Low vitamin D levels may increase risk of Type 1 diabetes

2013-02-05
Boston, MA – Having adequate levels of vitamin D during young adulthood may reduce the risk of adult-onset type 1 diabetes by as much as 50%, according to researchers at Harvard School of Public Health (HSPH). The findings, if confirmed in future studies, could lead to a role for vitamin D supplementation in preventing this serious autoimmune disease in adults. The study was published online February 3, 2013 and will appear in the March 1 print edition of the American Journal of Epidemiology. "It is surprising that a serious disease such as type 1 diabetes could perhaps ...

Climate change impacts to US coasts threaten public health, safety and economy

2013-02-05
According to a new technical report, the effects of climate change will continue to threaten the health and vitality of U.S. coastal communities' social, economic and natural systems. The report, Coastal Impacts, Adaptation, and Vulnerabilities: a technical input to the 2013 National Climate Assessment, authored by leading scientists and experts, emphasizes the need for increased coordination and planning to ensure U.S. coastal communities are resilient against the effects of climate change. The recently-released report examines and describes climate change impacts on ...
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