Bunny Bop transforms the childhood classic whack-a-mole game into a fast and furious frolic through the springtime fields. Game play is deceptively simple - bops those bunnies on the head as fast as you can, but keep an eye on the carrot supply. If you let one of those pesky bunnies slip away, it will steal a carrot, and you don't want that to happen! Bunny Bop is fun for all ages, with adorable graphics and addictive music. Start bopping! Download for iPhone/iPad: https://itunes.apple.com/us/app/smash-vote/id611038484?ls=1&mt=8 Download for Android: https://play.google.com/store/apps/details?id=air.com.mightybits.bunnybopMighty ...

They say truth is stranger than fiction, and Indie filmmaker Alan "Al Profit" Bradley proves that old saying true with his new movie "The Ghost of Saint Aubin". Shot entirely on location in Detroit, the film recently scored national distribution through Green Apple Entertainment. Saint Aubin is one of Detroit Michigan's oldest streets-and the site of some of the city's bloodiest crimes. "The Ghost of Saint Aubin" weaves incredible true events on Saint Aubin street from the 1800s, 1920s, and 1990s into a fictional tale of love, murder, and ...

Pittasoft, a dashboard camera company in Korea, has recently launched a brand-new product - BlackVue Wi-Fi DR500GW-HD dash cam. International sales started January 2013. BlackVue Wi-Fi DR500GW-HD records smooth Full HD (1920x1080p) video at 30fps. Full HD resolution is necessary to clearly capture license plates of accident participants. Its megapixel lens and 2MP CMOS sensor ensure crisp video quality in both daytime and nighttime. High compression technology allows the recording of more footage on the same capacity SD card. One more feature of BlackVue Wi-Fi DR500GW-HD ...

Guest Conductors include James Judd, Matthias Bamert and Conductor Laureate Ignat Solzhenitsyn. Soloists include HJ Lim, Pablo Sainz Villegas, Miho Saegusa, Catherine Michel, Jeffrey Khaner and Esther Yoo. A World Premiere Harp Concerto by Grammy-nominated and Academy Award and Golden Globe-winning composer Michel Legrand. Single tickets as low as $24 in the Perelman Theater. Season includes a special performance in the Kimmel Center's Verizon Hall with works featuring the Fred J. Cooper Memorial Organ. A founding resident company of The Kimmel Center for ...

Brake, the road safety charity, is partnering with Autoglass to launch a new national campaign promoting road safety. The free Bosch wipers initiative urges drivers to consider the road safety implications of poor visibility and raises awareness of the essential role windscreen wipers play in allowing drivers to maintain good visibility. The joint activity follows the news that the Department for Transport's road safety publicity budget has been slashed from GBP19m in 2008/09*** to GBP3.9m in 2011/12. As a result, the Government announced it would no longer invest ...

The Park Inn by Radisson Muscat has announced the expansion of its meeting room capacity and facilities. The blue room has been renovated over the summer and can now accommodate approximately 97 to 130 people as opposed to its previous capacity of 35 to 45. In addition, the banqueting menus have been given a facelift, with guests now having a fresh choice of food options suited for meetings and events and new chairs and tables. The hotel in Muscat offers ideal conference facilities, located only 15 kilometres from Muscat airport and just minutes from the city's ...

As success rates in treating childhood cancers have improved, greater emphasis is being placed on quality of life issues following successful treatment. Many cancer treatments can lead to infertility, but there are few methods to preserve the fertility of children who have not entered puberty. Spermatogonial stem cells (SSCs), which produce sperm cells, are present prior to the start of puberty. In theory, SSCs could be removed via biopsy prior to the start of treatment and then retransplanted following remission; however, there is a potential risk of reintroducing malignant ...

Mycobacterium ulcerans infects the skin and subcutaneous tissues and secretes a lipid toxin, mycolactone, which causes open skin lesions, known as Buruli ulcers. In this issue of the Journal of Clinical Investigation, researchers led by Caroline Demangel at the Pasteur Institue in Paris investigated the molecular actions of mycolactone and found that it dysregulates the cellular skeleton (cytoskeleton) through activation of a protein known as N-WASP. They found that excessive N-WASP activity caused defects in cell adhesion and migration that impaired the integrity of the ...

Cytoskeletal dysregulation underlies Buruli ulcer formation Mycobacterium ulcerans infects the skin and subcutaneous tissues and secretes a lipid toxin, mycolactone, which causes open skin lesions, known as Buruli ulcers. In this issue of the Journal of Clinical Investigation, researchers led by Caroline Demangel at the Pasteur Institue in Paris investigated the molecular actions of mycolactone and found that it dysregulates the cellular skeleton (cytoskeleton) through activation of a protein known as N-WASP. They found that excessive N-WASP activity caused defects in ...

Arnhem, 11 March 2013 - A new study by British scientists reveals that motile Escherichia coli isolates demonstrated significant activation of NF-κB signaling suggesting that flagellin plays a key role in up-regulating the host innate defences against urinary tract infections (UTIs). UTIs are commonly caused by Escherichia coli. The host innate defences function to protect the uro-epithelium from microbial assault via a variety of mechanisms. These include NF-κB signalling pathways activated via cell-surface Toll-like-receptors responding to bacterial pathogen ...

Arnhem, 11 March 2013- Multi-peptide vaccination therapy combined with the low-dose steroid drug dexamethasone shows promise in treating chemotherapy-naive castration resistant prostate cancer (CRPC) patients. The study, which won the third prize for best abstract in oncology at the 28th European Association of Urology Congress held in Milan, Italy from 15 to 19 March, showed the promising benefit of this combination therapy in patients who are chemotherapy-naive or those not yet exposed to specific antigens. "Results of our randomized prospective study suggest that ...

BUFFALO, N.Y. – The first controlled clinical trial to test the safety and efficacy of interventional endovascular therapy on the symptoms and progression of multiple sclerosis has found that the intervention, sometimes called the "liberation treatment," which has attracted intense interest in the global MS community, does not improve patient outcomes. In a few cases, the treatment made symptoms worse. University at Buffalo researchers will present their results in an "Emerging Science" poster session March 20 at the annual American Academy of Neurology meeting in San ...

Scientists at Johannes Gutenberg University Mainz (JGU) and the Max Planck Institute for Polymer Research (MPI-P) in Germany have created a new synthetic hybrid material with a mineral content of almost 90 percent, yet extremely flexible. They imitated the structural elements found in most sea sponges and recreated the sponge spicules using the natural mineral calcium carbonate and a protein of the sponge. Natural minerals are usually very hard and prickly, as fragile as porcelain. Amazingly, the synthetic spicules are superior to their natural counterparts in terms of ...

SAN DIEGO - A series of studies demonstrate improved detection of the second most common form of dementia, providing diagnostic specificity that clears the way for refined clinical trials testing targeted treatments. The new research is being presented by experts from the Perelman School of Medicine at the University of Pennsylvania at the American Academy of Neurology's 65th Annual Meeting in San Diego March 16-23, 2013. Frontotemporal degeneration, the most common dementia in people under 60, can be hereditary or sporadic in nature and caused by one of two different ...

SAN DIEGO - Telestroke programs substantially improve access to life-saving stroke care, extending coverage to less populated areas in an effort to reduce disparities in stroke care access. A new study by researchers from the Perelman School of Medicine at the University of Pennsylvania, being presented at the American Academy of Neurology's 65th Annual Meeting in San Diego March 16-23, 2013, found that telemedicine programs in Oregon pushed stroke coverage into previously uncovered, less populated areas and expanded coverage by approximately 40 percent. "Telestroke ...

EAST LANSING, Mich. --- Scientists have discovered a molecular process in the brain triggered by cocaine use that could provide a target for treatments to prevent or reverse addiction to the drug. Reporting in the Journal of Neuroscience, Michigan State University neuroscientist A.J. Robison and colleagues say cocaine alters the nucleus accumbens, the brain's pleasure center that responds to stimuli such as food, sex and drugs. "Understanding what happens molecularly to this brain region during long-term exposure to drugs might give us insight into how addiction occurs," ...

TALLAHASSEE, Fla. — Oil from the 2010 Deepwater Horizon spill acted as a catalyst for plankton and other surface materials to clump together and fall to the sea floor in a massive sedimentation event that researchers are calling a "dirty blizzard." Jeff Chanton, the John Widmer Winchester Professor of Oceanography in the Department of Earth, Ocean and Atmospheric Science at Florida State University, is one of the members of the Deep-C Consortium who presented the dirty blizzard hypothesis at a recent conference in New Orleans that focused on the effects of the oil spill ...

SAN DIEGO – Injecting synthetic tau fibrils into animal models induces Alzheimer's-like tau tangles and imitates the spread of tau pathology, according to research from the Perelman School of Medicine at the University of Pennsylvania being presented at the American Academy of Neurology's 65th Annual Meeting in San Diego March 16-23, 2013. This Alzheimer's research, along with additional Parkinson's research from Penn and beyond, further demonstrates the cell-to-cell transmission of neurodegenerative proteins. John Q. Trojanowski, MD, PhD, co-director of the Center for ...

West Orange, NJ. March 15, 2013. Kessler Foundation scientists and their colleagues will discuss their progress in rehabilitation research at the upcoming 65th Annual American Academy of Neurology Conference at the San Diego Convention Center in San Diego, CA, March 16 – 23. A.M. Barrett, MD, director of Stroke Rehabilitation at Kessler Foundation will present on Pharmacologic Enhancement of Stroke Rehabilitation on Friday March 22, 2013 as part of a Specialty in Focus session on Neurorehabilitation Enhancement Techniques. This session addresses the contribution of brain ...

Humans aren't the only species with a sweet tooth. Research from North Carolina State University shows that the invasive spotted-wing vinegar fly (Drosophila suzukii) also prefers sweet, soft fruit – giving us new insight into a species that has spread across the United States over the past four years and threatens to cause hundreds of millions of dollars in damage to U.S. fruit crops. "Because we know that D. suzukii prefers softer, sweeter fruit, we can focus our research efforts into which wild fruits may serve as reservoirs for this species and help identify new crops ...

COLUMBUS, Ohio—A new National Academy of Sciences report identifies tools that would help miners devise their own means of escape when trapped underground. In part, the report suggests that The National Institute of Occupational Safety and Health (NIOSH) and the Mine Safety and Health Administration (MSHA) work closely with technology companies to develop new communications and tracking devices—ones that keep working underground after a mining accident. It also suggests that NIOSH and MSHA work with mining companies to enable frequent escape drills and extensive training ...

Mindfulness is a form of meditation therapy focused on exercising 'attentiveness'. Depression is often rooted in a downward spiral of negative feelings and worries. Once a person learns to more quickly recognise these feelings and thoughts, he or she can intervene before depression sinks in. While mindfulness has already been widely tested and applied in patients with depression, this is the first time the method has been studied in a large group of adolescents in a school-based setting, using a randomised controlled design. The study was carried out at five middle schools ...

VIDEO: Animation of spin waves excited by a transient magnetic field pulse in a nanomagnet, as simulated with NIST micromagnetics software (Object Oriented MicroMagnetic Framework, or OOMMF). Click here for more information. Researchers at the National Institute of Standards and Technology (NIST) have developed a new microscope able to view and measure an important but elusive property of the nanoscale magnets used in an advanced, experimental form of digital memory. The new instrument ...

Today archaeologists unearthed a 'Black Death' grave in London, containing more than a dozen skeletons of people suspected to have died from the plague. The victims are thought to have died during the 14th century and archaeologists anticipate finding many more as they excavate the site. The Plague is by definition a re-emerging infectious disease which affects the lungs and is highly contagious, leading to mass outbreaks across populations. History shows us that population levels suffered globally due to the plague, with around 75 million people globally perishing during ...

The genome of an extinct Australian frog has been revived and reactivated by a team of scientists using sophisticated cloning technology to implant a "dead" cell nucleus into a fresh egg from another frog species. The bizarre gastric-brooding frog, Rheobatrachus silus – which uniquely swallowed its eggs, brooded its young in its stomach and gave birth through its mouth - became extinct in 1983. But the Lazarus Project team has been able to recover cell nuclei from tissues collected in the 1970s and kept for 40 years in a conventional deep freezer. The "de-extinction" ...