Virginia Commonwealth University researchers studying a key molecular player called Hsp70 that is responsible for protein homeostasis have uncovered how it binds together with another molecule responsible for intracellular energy transfer to enhance its overall activity and efficiency – details that have previously not been well understood. Heat shock proteins, particularly the 70-kilodalton heat shock proteins, Hsp70, are important for cellular processes such as protein folding and protecting cells from stress. It is also involved with protein assembly, degradation and ...

Structural biologists from Rice University and Baylor College of Medicine (BCM) have captured the first three-dimensional crystalline snapshot of a critical but fleeting process that takes place thousands of times per second in each human cell. The research appears online today in the journal Cell Reports and could prove useful in the study of cancer and other diseases. The biological "freeze-frame" shows the initial step in the formation of actin, a sturdy strand-like filament that is vital for humans. Actin filaments help cells maintain their shape. The filaments, which ...

Salmon and other native freshwater fish in California will likely become extinct within the next century due to climate change if current trends continue, ceding their habitats to non-native fish, predicts a study by scientists from the Center for Watershed Sciences at the University of California, Davis. The study, published online in May in the journal PLOS ONE, assessed how vulnerable each freshwater species in California is to climate change and estimated the likelihood that those species would become extinct in 100 years. The researchers found that, of 121 native ...

Two Johns Hopkins gynecologic surgeons are among the first in the nation to perform a robotic hysterectomy using a single, small incision. Amanda Nickles Fader, M.D., associate professor of gynecologic oncology and director of the Kelly Gynecologic Oncology Service and the Minimally Invasive Surgery Center in the Department of Gynecology and Obstetrics; and Stacey Scheib, M.D., assistant professor of gynecology and obstetrics and director of the Multidisciplinary Fibroid Center in the Division of Gynecologic Specialties at Johns Hopkins, recently performed other several ...

NJIT Distinguished Professor and electrical engineer Atam Dhawan hits the lecture trail again this summer as a distinguished speaker for an IEEE life sciences lecture series. His focus will be how "Point of Care Healthcare" can reduce illness, improve the quality of life, and stop spiraling healthcare costs. Dhawan, who will stop at conferences in Japan, Colombia and Croatia, tells audiences about the following. If you aren't already using a "wearable" sensor—whether it's a watch that reads your blood pressure or a temperature strip for your child's forehead—you soon ...

Research has shown that healthy behaviors are associated with a lower risk of Alzheimer's disease and dementia, but less is known about the potential link between positive lifestyle choices and milder memory complaints, especially those that occur earlier in life and could be the first indicators of later problems. To examine the impact of these lifestyle choices on memory throughout adult life, UCLA researchers and the Gallup organization collaborated on a nationwide poll of more than 18,500 individuals between the ages of 18 and 99. Respondents were surveyed about ...

While there has been a steep decline in kids' consumption of sugar-sweetened beverages in California, African-American and Latino children may be replacing soda with 100 percent fruit juice while their white peers are not, according to a new study from UC San Francisco. The study was the first to compare trends of sugar-sweetened beverages and 100 percent juice consumption in California. "The decrease in the consumption of sugar-sweetened beverages among kids is a promising public health trend," said Amy Beck, MD, MPH, lead author and pediatrician at UCSF Benioff ...

GLYX-13, a molecular cousin to ketamine, induces similar antidepressant results without the street drug side effects, reported a study funded by the National Institute of Mental Health (NIMH) that was published last month in Neuropsychopharmacology. Major depression affects about 10 percent of the adult population and is the second leading cause of disability in U.S. adults, according to the World Health Organization. Despite the availability of several different classes of antidepressant drugs such as selective serotonin reuptake inhibitors (SSRIs), 30 to 40 percent ...

PHILADELPHIA — A newly developed, single-step Raman spectroscopy algorithm has the potential to simultaneously detect microcalcifications and enable diagnosis of the associated breast lesions with high precision, according to data published in Cancer Research, a journal of the American Association for Cancer Research. "Nearly 1.6 million breast biopsies are performed and roughly 250,000 new breast cancers are diagnosed in the Unites States each year," said Ishan Barman, Ph.D., postdoctoral fellow at the Massachusetts Institute of Technology in Cambridge and the study's ...

INDIANAPOLIS -- An Indiana University study that compared the performance of elite track and field athletes younger than 20 and those 20 and older found that only a minority of the star junior athletes saw similar success as senior athletes. The researchers think physical maturation is behind the disparity, with athletes who mature early reaping the benefits early, seeing their best times, jumps and throws at a younger age than Olympians, many of whom mature later. "You see it in a lot of sports," said Robert Chapman, assistant professor in the IU School of Public ...

Keep your business in the black when negotiating a commercial lease Article provided by Ethan A. Glaubiger Visit us at http://www.glaubigerlaw.com To paraphrase an old adage, there are three things that are most important in real estate: location, location, location. In this slowly recovering economy, the large number of vacancies in commercial buildings means that you may even have several desirable locations to choose from when selecting a site for your business. But not so fast; simply having a location in mind does not mean you have to sacrifice favorable ...

Deaths due to distracted driving may be underreported Article provided by Kamensky Cohen & Riechelson Visit us at http://www.kcrlawfirm.com In recent years, safety experts, lawmakers and even U.S. Department of Transportation head Ray LaHood have spoken out against the dangers of distracted driving. No matter the behavior - be it texting while driving or talking on a cell phone while behind the wheel - everyone agrees that driving while distracted is extremely dangerous. A new study indicates, however, that the practice may, in fact, be far deadlier than previously ...

Ohio woman sentenced to 8 years in prison for fatal DUI hit-and-run Article provided by Horwitz & Horwitz, LLC Visit us at http://www.horwitzlawsite.com Most people know that Ohio law prohibits people from operating a vehicle while they are under the influence of alcohol. However, not everyone internalizes just how dangerous drunk driving can be, nor do they realize how serious the legal consequences can be if they cause a car accident that injures or kills another person. A recent case in Logan County should serve as a cautionary tale to anyone who drinks ...

Bringing a foreign spouse or fiancee to the United States Article provided by Vickerstaff Law Office, PSC Visit us at http://www.vickerstafflaw.com We are increasingly living in a global society. As part of this, it has become very common for American citizens to spend extended periods abroad for work, school or military service. Some of these people end up falling in love while they are away, and they want to bring their new spouse or fiancee back to the United States when they return home. This can be done by obtaining the appropriate visa. However, because ...

U.S. to impose extra scrutiny on student visa holders Article provided by Vickerstaff Law Office, PSC Visit us at http://www.vickerstafflaw.com In the wake of the Boston bombings, the U.S. Department of Homeland Security has ordered Customs and Border Protection Officers to impose extra scrutiny on individuals entering the United States on student visas.In the wake of the Boston bombings, the U.S. Department of Homeland Security has ordered Customs and Border Protection Officers to impose extra scrutiny on individuals entering the United States on student visas. ...

Alabama hospital shows that medication errors can be reduced Article provided by Salter Ferguson, LLC Visit us at http://www.seriousinjuries.org/ Pharmaceuticals can do amazing things for patients when administered properly. Yet, there are many moving parts in getting the right medication to the right patient. Preventable mistakes like administering an incorrect dose, providing medication at the wrong time or mixing up patient charts can have serious, even life threatening consequences. Since 2000, almost 100,000 medication errors have been reported to the U.S. ...

New York courts throw out prenup signed under allure of false promise Article provided by Kelton & Teichner Visit us at http://www.queensnassaufamilylaw.com/ The media has had a field day with the story of divorcing spouses Elizabeth Cioffi-Petrakis and her multimillionaire husband real estate mogul Peter Petrakis. A New York appeals court agreed with a Long Island judge who had found that the couple's prenuptial agreement, which was very financially disadvantageous for the wife, should be invalidated because the husband induced the wife to sign it by verbal ...

Head-on collision injures three Article provided by Law Offices of Glenn W. Cunningham Visit us at http://www.cunninghamfirm.com Head-on collisions can be a particularly tragic event for those involved, particularly if the vehicles are traveling at a high speed. Fox News recently reported that a head-on collision in Southwest Bexar County caused one person to be flown by AirLife to University Hospital and two others taken to University Hospital by ambulance. Negligent and reckless driving is dangerous, and if an injury occurs from another driver's negligent and ...

Implications of the Missouri sex offender registry Article provided by Harper, Evans, Wade & Netemeyer Visit us at http://www.lawmissouricriminaldefense.com The Missouri sex offender registry is designed to let residents find out where a convicted sex offender lives, where an offender works, the car the offender drives, as well as the alleged crime that led to the conviction. Although it was created to keep people informed, the Missouri sex offender registry prohibits those convicted of a sex offense from moving on with their lives after they have paid their ...

OSHA penalizes lax attention to safety Article provided by Jeffrey S. Gross Visit us at http://www.philaworkerscomp.com/ The Occupational Safety and Health Administration, an agency of the U.S. Department of Labor, recently announced that a Pennsylvania employer had been cited for a safety violation that led to a worker's death in August 2012. The fatal incident took place at a gas well in Ringgold, Pennsylvania. The employer, J.R. Resources, did not provide a worker with flame-resistant garments. When a flash fire occurred, he was severely burned and did not ...

Slip and fall accidents result in numerous injuries Article provided by The Law Firm of Ted B. Lyon & Associates Visit us at http://www.tedlyon.com "Slip and fall" is a term that refers to a personal injury claim where a person slips or trips and falls, resulting in injury, often on someone else's property. Dangers such as torn carpeting, uneven flooring, poor lighting, narrow stairs or wet floors can all cause someone to slip and fall. According to the National Floor Safety Institute, slip and fall accidents result in approximately one million ...

New report: Millions of American workers killed, injured every year Article provided by Norfleet and Lafferty LLC Visit us at http://www.norlaflaw.com/ When a sudden tragedy strikes, the news media are quick to fill the airwaves with instant coverage. From acts of terrorism to natural disasters, any event that costs even a few innocent lives grabs headlines for days. Yet, every single day, dozens of American workers are killed either on the job or from occupational disease, and the plight of them and their families goes largely unsung. For those impacted by a ...

Multi-car crash results in damages and injuries Article provided by Bruce A. Wallace, III Visit us at http://www.bawallacelaw.com/ Car crashes on the highway can result in more than just congested traffic. When a driver makes a careless decision behind the wheel on the highway, that negligent driver may be held liable for any resulting damages and injuries. On the highway it's important for drivers to pay attention and to be mindful of the road conditions. This is true whether it's weather-related or a high-traffic time of day. Four-car crash causes fire and ...

New Jersey workers' compensation process Article provided by Edward Rogan & Associates LLC Visit us at http://www.rogan-lawfirm.com All forms of employment carry some degree of risk. Of course, individuals working in certain industries, such as construction and other labor-intensive fields, may face a higher risk of injury. No matter the industry, however, all New Jersey workers should be aware of their right to workers' compensation benefits in case they experience a job-related injury. New Jersey's law prohibiting such individuals from litigating their ...

Macomb County drunken driving stats are revealing Article provided by The Hirsch Law Firm, PLLC Visit us at http://www.jonhirschlaw.com County-by-county statistics collected by the state demonstrate the seriousness of the drunk driving problem in Macomb County, as statistic compiled for 2011 demonstrate. Drunk drivers are responsible for many injuries and fatalities. The Macomb County results In 2011 over 6,800 people sustained personal injuries in motor vehicle accidents in Macomb County. During the same period, 48 people were killed. Alcohol was a factor ...