Natural chemicals found in green tea and red wine may disrupt a key step of the Alzheimer's disease pathway, according to new research from the University of Leeds. In early-stage laboratory experiments, the researchers identified the process which allows harmful clumps of protein to latch on to brain cells, causing them to die. They were able to interrupt this pathway using the purified extracts of EGCG from green tea and resveratrol from red wine. The findings, published in the Journal of Biological Chemistry, offer potential new targets for developing drugs to treat ...

DURHAM, N.C. -- A father's obesity is one factor that may influence his children's health and potentially raise their risk for diseases like cancer, according to new research from Duke Medicine. The study, which appears Feb. 6 in the journal BMC Medicine, is the first in humans to show that paternal obesity may alter a genetic mechanism in the next generation, suggesting that a father's lifestyle factors may be transmitted to his children. "Understanding the risks of the current Western lifestyle on future generations is important," said molecular biologist Adelheid ...

CAMBRIDGE, MA -- Increased natural gas production is seen as a crucial step away from the greenhouse gas emissions of coal plants and toward U.S. energy independence. But natural gas wells have problems: Large volumes of deep water, often heavily laden with salts and minerals, flow out along with the gas. That so-called "produced water" must be disposed of, or cleaned. Now, a process developed by engineers at MIT could solve the problem and produce clean water at relatively low cost. After further development, the process could also lead to inexpensive, efficient desalination ...

(SACRAMENTO, Calif.) — Deaf and hard of hearing (DHoH) people must overcome significant professional barriers, particularly in health care professions. A number of accommodations are available for hearing-impaired physicians, such as electronic stethoscopes and closed-captioning technologies, but are these approaches making a difference? A team of researchers from the University of California, Davis, the University of Texas Health Science Center at San Antonio and the University of Michigan surveyed DHoH physicians and medical students to determine whether these and ...

ARLINGTON, Va. —The Navy's fifth Littoral Combat Ship (LCS), Milwaukee, will be the first to benefit from new high-power density waterjets aimed at staving off rudder and propeller damage experienced on high-speed ships. The product of an Office of Naval Research (ONR) Future Naval Capabilities (FNC) program, the waterjets arrived last month at the Marinette Marine shipyard in Wisconsin, where Milwaukee (LCS 5) is under construction. "We believe these waterjets are the future," said Dr. Ki-Han Kim, program manager in ONR's Ship Systems and Engineering Research Division. ...

ANN ARBOR, Mich. — When it comes to gene sequencing and personalized medicine for cancer, spotting an aberrant kinase is a home run. The proteins are relatively easy to target with drugs and plenty of kinase inhibitors already exist. Now in a new study, University of Michigan Comprehensive Cancer Center researchers assess the complete landscape of a cancer's "kinome" expression and determine which kinases are acting up in a particular tumor. They go on to show that those particular kinases can be targeted with drugs – potentially combining multiple drugs to target multiple ...

WEST LAFAYETTE, Ind. – Researchers are improving the performance of technologies ranging from medical CT scanners to digital cameras using a system of models to extract specific information from huge collections of data and then reconstructing images like a jigsaw puzzle. The new approach is called model-based iterative reconstruction, or MBIR. "It's more-or-less how humans solve problems by trial and error, assessing probability and discarding extraneous information," said Charles Bouman, Purdue University's Michael and Katherine Birck Professor of Electrical and Computer ...

EurekAlert!'s most-viewed news release from 2012 focused on a breakthrough in the treatment of obesity and related diseases using a combination of hormones, tested in mice, that resulted in weight loss and lowered blood sugar without negative side effects. The theme of obesity was prominent in three other most-viewed news releases on EurekAlert! during 2012.. Other topics were mental health, neuroscience, marine conservation, human behavioral science, and progress toward a male contraceptive pill. EurekAlert! is the global science news service operated by the American ...

A pair of commentaries to appear in an upcoming issue of the journal Antimicrobial Agents and Chemotherapy highlight a debate within the public health community surrounding Centers for Disease Control and Prevention (CDC) recommendations for treatment of exposed individuals during last year's fungal meningitis outbreak. Manuscripts of the commentaries were published ahead of print today on the journal's webpage. "I will try to offer sufficient documentation to show there are alternative approaches worthy of consideration," writes David A Stevens of Stanford University ...

Ever since Austrian scientist Erwin Schrodinger put his unfortunate cat in a box, his fellow physicists have been using something called quantum theory to explain and understand the nature of waves and particles. But a new paper by physics professor Andreas Albrecht and graduate student Dan Phillips at the University of California, Davis, makes the case that these quantum fluctuations actually are responsible for the probability of all actions, with far-reaching implications for theories of the universe. Quantum theory is a branch of theoretical physics that strives ...

LA JOLLA, CA----You might think you have nothing in common with mustard except hotdogs. Yet based on research in a plant from the mustard family, Salk scientists have discovered a possible explanation for how organisms, including humans, directly regulate chemical reactions that quickly adjust the growth of organs. These findings overturn conventional views of how different body parts coordinate their growth, shedding light on the development of more productive plants and new therapies for metabolic diseases. Metabolism refers to all the chemical reactions in the body ...

The vast edges of our solar system – the boundary at the edge of our heliosphere where material streaming out from the sun interacts with the galactic material – is essentially invisible. It emits no light and no conventional telescope can see it. However, particles from inside the solar system bounce off this boundary and neutral atoms from that collision stream inward. Those particles can be observed by instruments on NASA's Interstellar Boundary Explorer (IBEX). Since those atoms act as fingerprints for the boundary from which they came, IBEX can map that boundary in ...

HOUSTON – (February 5, 2013) – American Indians are at much greater risk of suicide after acute alcohol intoxication, according to a study led by researchers at The University of Texas Health Science Center at Houston (UTHealth). The study examined the prevalence and social demographic correlates of suicide involving acute alcohol intoxication among United States ethnic minorities. Results will be published in the May 2013 issue of Alcoholism: Clinical & Experimental Research and are currently available at Early View. "Some reviews suggest that people with alcohol ...

An allergic reaction to cockroaches is a major contributor to asthma in urban children, but new research suggests that the insects are just one part of a more complex story. Very early exposure to certain components of air pollution can increase the risk of developing a cockroach allergy by age 7 and children with a common mutation in a gene called GSTM may be especially vulnerable. Researchers at the Columbia Center for Children's Environmental Health at the Mailman School of Public Health published the findings, the first on this interplay of risk factors, in the February ...

Mothers who are exposed to particulate air pollution of the type emitted by vehicles, urban heating and coal power plants are significantly more likely to bear children of low birth weight, according to an international study led by co-principal investigator Tracey J. Woodruff, PhD, MPH, professor of obstetrics and gynecology and reproductive sciences at UC San Francisco along with Jennifer Parker, PhD, of the National Center for Health Statistics, Centers for Disease Control and Prevention. The study, the largest of its kind ever performed, analyzed data collected from ...

After a year of studying up close the symbiotic relationship between a mosquito-sized bug and a fungus, a Simon Fraser University biologist has advanced the scientific understanding of biological diversity. Jeffrey Joy has discovered that symbiosis — a relationship between two or more organisms that can be parasitic or mutualistic — is as much the mother of biological diversity as predation and competition. The Proceedings of the Royal Society of London Series B journal has just published the post-doctoral researcher's findings online. They advance Joy's previous ...

Jobs Difficult to Find for Those Over 55 Many employees continue to experience difficulties finding jobs in this tough economy. Unfortunately, research shows that those over the age of 55 seem to have an even greater struggle than most jobless Americans. According to the AARP, unemployment rates for Americans 55 and older surged from 490,000 in 2000, to 2,114,000 in 2009. Reuters also reports that the number of workers over 55 struggling with long-term unemployment has more than doubled since 2007. In some cases, employee rights may come into play. Both federal ...

State and Federal Authorities Cracking Down on Synthetic Drugs State and federal authorities once lagged behind on the growing synthetic drug trend. The constantly changing chemical compounds in synthetic drugs, which mimic either the effects of methamphetamine or marijuana, made it a legal high for many users, who could purchase them at smoke shops and gas stations. This is no longer the case. Growing alarm at the frequent use and corresponding dangers of synthetic drug use has prompted state and federal authorities to issue harsh punishments to those found selling ...

What to tell (and not tell) a child about a divorce A divorce is a high-stress event that makes parenting more difficult than ever. A child may have many several reactions and emotions to a divorce, and putting that child's needs first is more important than ever. Parents know this, of course, but it can be difficult to know how to say and do the right things to ensure a child is emotionally stable and able to move on after the divorce. Speaking to children when divorcing It is important to speak to children about divorce as soon as plans are made concrete. If ...

Financial issues to consider when getting a divorce If you are going through a divorce, you know that your whole financial life is about to change. But if you prepare for it, the transition does not have to be difficult. The following tips can help you deal with your money matters as you are dissolving your marriage. Make an assessment about what you have To assess your financial condition, it is best to make a list of what you have, as well is what you owe. Make a list of your shared properties, investments and retirement funds , so you can give a detailed statement ...

Part of New York City's stop and frisk policy ruled unconstitutional Recently, a federal judge ruled a portion of New York City's controversial stop and frisk policy unconstitutional. Undeterred, New York City plans to appeal the ruling. The federal judge's ruling was one of three federal challenges to the policy. The federal judge found that the policy violated the civil liberties of residents who were stopped for trespass because police lacked reasonable suspicion for the stop. The Fourth Amendment and reasonable stops The Fourth Amendment protects individuals ...

Federal court: Employers can refuse to hire based on past bankruptcies Filing for bankruptcy is a major decision. In many cases, a Chapter 7 or Chapter 13 bankruptcy can be the best way for individuals to get out from under overwhelming debt. However, there are some downsides to filing for bankruptcy -- most notably, bankruptcy will negatively a person's credit score and it can make it difficult to qualify for a mortgage or a major loan. Recently, a new complication for bankruptcy filers has emerged. More and more, employers are looking into job applicants' credit ...

Valuable tips for managing finances during a divorce Although Missouri residents know the divorce process is challenging, divorcing couples may not be aware of the complex financial issues involved. Competing interests can also further complicate the situation. Finances are one of the biggest sources of stress when going through a divorce,and that stress may be especially intense for individuals who are not familiar with handling finances. The following tips are a good starting place for dealing with these issues. Financial tips during a divorce It is wise ...

New Treatment Shows Promise for Those with Spinal Cord Injuries According to the Centers for Disease Control and Prevention (CDC), approximately 200,000 people in the United States are currently living with a severe spinal cord injury (SCI). Experts estimate that an additional 12,000 to 20,000 people in the United States suffer an SCI each year. The cost of treating these injuries is significant: the average annual medical cost for someone with a spinal cord injury is anywhere from $15,000 to $30,000, depending on the severity of the injury. Spinal cord injuries are ...

Women Struggling With Medical Debt in Oregon and Across the US According to a report issued by the Commonwealth Fund, a non-profit group advocating for health care reform, women in the U.S. have more problems paying their medical bills than in other industrialized nations around the world. Women struggle with medical debt more often than men for a number of reasons, and some women may not be aware that filing bankruptcy may be one way to deal with overwhelming medical bills. Women in the U.S. Have More Medical Debt The Commonwealth Fund compared the number of women ...