Boston, Mass.—By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces metastatic spread in mouse models of prostate, breast and lung cancer. The findings suggest that a prosaposin-based drug could potentially block metastasis in a variety of cancers. The study team, led by Randolph Watnick, PhD, at Boston Children's Hospital, Vivek Mittal, PhD, at Weill Cornell Medical College and Lars Akslen, MD, PhD, ...

AURORA, Colo. (May 21, 2013) – Research into genetic features of pulmonary fibrosis by physicians and scientists at the University of Colorado School of Medicine may lead to improved treatment of this deadly lung disease, according to a paper published online by JAMA. The study found that a particular genetic variation helps predict survival in some cases of pulmonary fibrosis, a chronic progressive disease with a median survival of three years. As a result of the study, researchers may want to consider including genetic testing in future clinical trials. The researchers ...

CINCINNATI—Using the Department of Defense Serum Repository (DoDSR), University of Cincinnati (UC) researchers have identified a number of biomarkers for inflammatory bowel disease (IBD), which could help with earlier diagnosis and intervention in those who have not yet shown symptoms. This finding, the first of its kind and led by UC's Bruce Yacyshyn, MD, is being presented via podium presentation by staff from Walter Reed National Military Medical Center at Digestive Disease Week 2013, being held May 18-21 in Orlando, Fla. The DoDSR is a biological repository operated ...

Boston – Adenotonsillectomy, or the removal of the adenoids and tonsils, is performed 500,000 times a year in the United States, often as a treatment for children with obstructive sleep apnea. However, the procedure's ability to improve a child's attention and executive functioning, behavior, sleep apnea symptoms, and quality of life has not been rigorously evaluated until now. A study led by Susan Redline, MD, MPH, director of the Program in Sleep and Cardiovascular Medicine and Associate Clinic Director of the Division of Sleep Medicine at Brigham and Women's Hospital ...

21 May 2013, Paris, France: One-year results from SOURCE XT – one of the largest, post-approval transcatheter aortic valve implantation (TAVI) registries to-date – reported today at EuroPCR 2013 show good clinical outcomes in routine clinical practice, with high rates of device success for all access approaches, valve sizes and delivery systems. The SOURCE XT Post-Approval Study followed up 2688 consecutively enrolled patients (mean age 81.5 years) undergoing TAVI with the Sapien XT heart valve at 93 centres in 17 countries between July 2010 and October 2011. Access was ...

21 May 2013, Paris, France: The Orsiro stent, which is a novel stent platform eluting sirolimus from a biodegradable polymer, demonstrated non-inferiority to the Xience Prime everolimus-eluting stent for the primary angiographic endpoint of in-stent late lumen loss at nine months in the results of an imaging substudy reported at EuroPCR 2013 today. The BIOFLOW-II substudy used intravascular ultrasound (IVUS) and optical coherence tomography (OCT) to quantitatively assess neointimal hyperplasia and stent apposition at nine months after treating patients with symptomatic ...

Using a "patient monitoring" device attached to a whale entangled in fishing gear, scientists showed for the first time how fishing lines changed a whale's diving and swimming behavior. The monitoring revealed how fishing gear hinders whales' ability to eat and migrate, depletes their energy as they drag gear for months or years, and can result in a slow death. The scientists in this entanglement response suction-cupped a cellphone-size device called a Dtag to a two-year-old female North Atlantic right whale called Eg 3911. The Dtag, developed at Woods Hole Oceanographic ...

CHESTNUT HILL, Mass. -- Is it permissible to harm one to save many? Those who tend to say "yes" when faced with this classic dilemma are likely to be deficient in a specific kind of empathy, according to a report published in the scientific journal PLOS ONE. Philosophers and psychologists have long argued about whether there is one "right" answer to such moral questions, be it utilitarian ethics, which advocates saving as many as possible, even if it requires personally harming an individual, or non-utilitarian principles, which mandate strict adherence to rules like ...

Parents must plan for summer parenting time in Oregon Article provided by Evashevski, Elliott, Cihak & Hediger, PC Visit us at http://www.eechlaw.com The academic school year is almost finished and many divorced or separated parents will need to adjust their routines. In Oregon, the summer months are a great time to go camping or enjoy the scenic coastline with children, but disputes over when vacations occur can be common. An Oregon child parenting time order that allows for every other weekend visits may allow a larger amount of time, such as one-half of the ...

DePuy Multi District Litigation in Ohio Article provided by Elk & Elk Co., Ltd. Visit us at http://www.elkandelkcanton.com/ Lawsuits from all over the country regarding the defective hip replacement manufactured by DePuy Orthopedics Inc. are being heard in U.S. District Court for the Northern District of Ohio in Toledo. The complaints have been consolidated in a multidistrict litigation (MDL) designed to speed up the legal process for plaintiffs and defendants and handle the many thousands of suits in a cost-effective manner. DePuy, which makes a variety of ...

Getting divorced in Arizona? You need to factor in taxes Article provided by Viles Law Office, LLC Visit us at http://www.vileslawoffices.com/ To paraphrase an old adage, the only certainties in life are death and taxes. At the end of your marriage, taxes are probably the last thing on your mind. But, when it comes time to split up the marital property, taking tax considerations into account can save you thousands in the long run. The face value of assets does not always accurately reflect their true worth Arizona is a community property state, which means ...

Attempts to limit construction defect lawsuits in Colorado shot down Article provided by Abrams & Associates, LLC Visit us at http://www.abramslaw.net Colorado laws have created a real problem for construction companies and homebuilders in the state. There is a high demand for real estate in the Denver metro area, especially for condominiums and townhomes located near popular light-rail stations. Transit-oriented developments (TODs) are not a new concept in this country and, a few years ago, the city and county of Denver began developing these living spaces ...

The words every parent dreads hearing while strolling the Champs-Elysees with their offspring: "Is there a McDonald's around here? I'm borrrrred!" You've scrimped and saved for months (maybe years) to bestow on your children something your parents weren't able to provide for you: a priceless education and exposure to the Art, Architecture and Cuisine of the great cities of Europe. But your kids just want to text their friends and hang out at a shopping mall. What can parents do to enthuse their young ones regarding this once-in-a-lifetime experience? "Educate ...

Shantytown, the Van Zant legacy continues... Following the successful release on "Redneck" in April, Shanytown releases "Peace of Mind". Any true fan of Rock & Roll can tell you about the Van Zant family of Jacksonville, Florida (known as the "First Family of Southern Rock"). They have produced three-major bands: "Lynyrd Skynyrd", "38 Special" and the "Johnny Van Zant Band". Now there is a proud new addition from Southern Rock's first family, a great new band called "Shantytown". And the Van ...

The Greenleaf-Elving Group of Keller Williams Realty Southwest in Las Vegas, NV are pleased to announce an open house showing on a beautiful dual-residence estate property in Southwest Las Vegas. This gorgeous custom-home sits on a half-acre lot over-looking undeveloped desert landscape. The primary living quarters are beautifully crafted into 3,558 square feet in just one story of comfort and design. The property features a custom pool and spa, and ample climate control garage parking for seven vehicles. The detached residence of this estate features over 2,000 square ...

As technology and the Internet continue to grow in popularity as the medium of choice for information gathering and shopping, many companies have chosen to ignore one basic fact: often, shoppers still prefer a product they can see and experience firsthand. Minneapolis deck builder UglyDeck.com has not forgotten this important element, and invites customers interested in maintenance free decks and other outdoor options such as deck railings and outdoor spiral staircases to visit their Burnsville showroom. The considerable showroom will enable homeowners to browse the ...

The Alliance of the Guardian Angels, in association with FirstRun.tv Network (www.FirstRun.tv) has begun production of "Angels In Action", a new reality television series that captures the true-life drama and action of the Guardian Angels as they patrol inner-cities and communities to help citizens and police fight crime. Unarmed, and putting their own safety at risk, the organized teams of brave volunteers encounter drug dealing, prostitution, thieves, and more, as they traverse the streets. The debut episode, which follows Guardian Angels chapter teams in Philadelphia, ...

Stacey Powell realized that small businesses need a simpler set of financial tools to provide financial clarity on the day she couldn't make payroll at the $3 million agency she was overseeing. She now empowers business owners daily by helping them understand and effectively use their financial information. Small Biz Thoughts has secured Powell as a feature speaker at their June IT Business Reboot 2013 Online Conference. Powell is the founder of Creating Answers, an organization dedicated to guiding businesses and individuals toward financial success. Karl W. Palachuk, ...

Prize winning author Nadine Love sponsored by Hay House and Balboa Press host a free online event titled "Make the Dragon Your Pet". Tuesday, June 11, 9 - 10 am, Queensland, Australia: Monday, June 10, 7 to 8 pm US Eastern. Nadine Love will address how to recognize the five foundation shaking fears that may be holding you back and tame your fear-dragon so that you can have the life that is your true destiny. Love invites participants to free themselves from self-sabotage, procrastination and self-doubt in this comprehensive workshop. "If you knew how ...

Carothers DiSante & Freudenberger LLP (CDF), a leading California labor and employment law firm, welcomes Amy Williams as senior counsel to bolster the firm's class action litigation defense group at its expanding Orange County office. Williams brings nearly a decade of proven experience in wage and hour class action litigation, delivering favorable outcomes for clients across a multitude of industries. "I am excited to join such a highly respected law firm that focuses exclusively on labor and employment law," said Williams. "I look forward to applying ...

Since the internet is becoming the main source of information gathering for potential employers and customers, an online image is now the first impression. More than 1,500 students, professionals and small business owners are expected to attend UNiCOMM 2013 (www.unicommsummit.com), scheduled for Saturday, October 5, 2013 at the Baltimore Convention Center. The theme, Discovering and Branding the Authentic Me, features a day of dynamic speakers covering personal branding in entrepreneurship, career development and social media. Attendees will learn innovative, forward-thinking ...

When you're flipping through the glossy pages of magazines like Veranda and Elle Decor, you might be wondering how designers source all those unique, grand pieces? Their method is to scour secret sources, such as Village Antiques, which has been steadily gaining traction in the Houston home decor consumer market. Village Antiques is an inspiring store where consumers can find completely unique antique furniture, one-of-a-kind pieces, and home accessories. Their pieces debunk the common misconception of traditional, stodgy antiques, and embrace, beautiful, stylish but ...

On May 24, 2013, Word Branch Publishing will release young adult author jerjonji's second novel, Four Winds. Coming on the heels of her highly acclaimed Panda Girl in 2012, Four Winds promises to be another success with adults, teens and tweens. In her second novel, jerjonji courageously addresses a difficult topic with great insight and sensitivity. She leads the reader into the lives of four characters haunted by nightmarish childhoods. We follow these characters as young adults, discovering the strange and often dangerous alliances they make, not only for survival, ...

The first 5 videos will feature ... Actors - Ian Smith and Kerry Armstrong TV personalities - Suzie Wilks, Pete Smith, Glenn Ridge, Red Symons, Vesna Tovenska Radio personalities - Adam Richard, Jo Stanley, Billy Pinnell, Tracy Bartram Comedians - Darren Casey, Sarah Kendall, Dave Hughes, Glenn Robbins,Kenny Kramer AFL champion and State MP Justin Madden ... and a very special appearance from Australian television legend Bert Newton. Despite having no budget, this pioneering program became Channel 31's highest rating show, and was the very first live, daily program ...

Metro Health Hospital has named Dr. Kevin Furlong its 2013 Nursing-Chosen Physician of the Year. The award is given annually by Metro Health's Professional Nursing Council, or PNC, to recognize a physician who exemplifies best practices and who also supports the role of nurses as part of the healthcare team. The hospital's clinical nursing staff proposes candidates, and nominations are reviewed by the 13-member PNC, with the recipient selected by secret ballot. Furlong serves as Metro's chief of staff. He is board-certified in internal medicine and practices at Metro ...