Worcester, Mass. – Damage to building structural elements, elevators, stairs, and fire protection systems caused by the shaking from a major earthquake can play a critical role in the spread of fire, hamper the ability of occupants to evacuate, and impede fire departments in their emergency response operations. These are among the conclusions of a groundbreaking study of post-earthquake building fire performance conducted in 2012 by researchers in the Department of Fire Protection Engineering at Worcester Polytechnic Institute (WPI). "When the ground stops shaking after ...

A team of USC scientists has identified a protein that can change DNA topology, making DNA twist up into a so-called "supercoil." The finding provides new insight about the role of the protein—known as mini-chromosome maintenance (MCM)—in cancer cells, which have high levels of MCM. Think about twisting one end of a rubber band while holding the other end still. After a few turns, it forms a neatly twisted rope. But if you keep on turning, the twisted band will twist back upon itself into an increasingly coiled-up knot. Similarly, a DNA molecule can be twisted and ...

Philadelphia, Pa. (March 11, 2013) – For HIV-infected patients whose disease is well-controlled by modern treatment, the risk of death is not significantly higher than in the general population, according to a study published in AIDS, official journal of the International AIDS Society. AIDS is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. The study suggests that patients with undetectable viral loads and near-normal levels of immune cells on state-of-the art antiretroviral therapy (ART) can expect to have about the same risk of death as ...

People with multiple sclerosis (MS) who were treated with combination therapy did not see significant clinical benefit over those treated with single drug therapy, but combination therapy did reduce the development of new lesions, according to an international research team led by The Mount Sinai Medical Center. The findings, part of the largest-ever MS trial sponsored by the National Institutes of Health, are published in the March 11 issue of Annals of Neurology. In the Phase III CombiRx trial, researchers led by Fred Lublin, MD, of The Mount Sinai Medical Center, sought ...

CHAMPAIGN, Ill. — Fitness DVDs are a multimillion-dollar business, and those targeting adults over the age of 55 are a major part of the market. With names like "Boomers on the Move," "Stronger Seniors" and "Ageless Yoga," the programs promise much, but few have ever been rigorously tested. "There are tons of DVDs out there, 20 percent of them are purchased by older adults, and with few exceptions there is no evidence that they work," said University of Illinois kinesiology and community health professor Edward McAuley, who led a new study testing the efficacy of a home-based ...

COLUMBUS, Ohio – New research shows that a tiny piece of RNA has an essential role in ensuring that embryonic tissue segments form properly. The study, conducted in chicken embryos, determined that this piece of RNA regulates cyclical gene activity that defines the timing of the formation of tissue segments that later become muscle and vertebrae. Genes involved in this activity are turned on and off in an oscillating pattern that matches the formation of each tissue segment. If the timing of these genes' activity doesn't remain tightly regulated, the tissue either won't ...

Scientists and policymakers from around the world will gather March 20-22 at the University of California, Davis, to grapple with the threats of climate change for global agriculture and recommend science-based actions to slow its effects while meeting the world's need for food, livelihood and sustainability. The Climate-Smart Agriculture Global Science Conference, planned in coordination with the World Bank, builds on a 2011 international meeting on this theme in the Netherlands. "Climate change, which brings severe weather events and more subtle but equally menacing ...

A new study conducted by researchers at the University of North Carolina at Chapel Hill and the University of Adelaide, Australia, has produced the strongest evidence yet that fluoride in drinking water provides dental health benefits to adults, even those who had not received fluoridated drinking water as children. In the first population-level study of its kind, the study shows that fluoridated drinking water prevents tooth decay for all adults regardless of age, and whether or not they consumed fluoridated water during childhood. Led by UNC School of Dentistry faculty ...

A new report from the Johns Hopkins Institute for Policy Studies reveals that nonprofit organizations are major employers and major sources of employment growth in countries throughout the world. The report draws on new data generated by statistical offices in 16 countries that have implemented a new United Nations Handbook on Nonprofit Institutions. This Handbook calls on national statistical offices to report on the economic scale and composition of nonprofit organizations in their countries for the first time. Key findings to date from implementation of this Handbook, ...

This press release is available in French. A single dose of an investigational anti-inflammatory drug called inclacumab considerably reduces damage to heart muscle during angioplasty (the opening of a blocked artery), according to a recent international clinical trial spearheaded by Dr. Jean-Claude Tardif, Director of the Research Centre at the Montreal Heart Institute, affiliated with the University of Montreal. Presented today in San Francisco at the prestigious American cardiology conference, these findings show great promise. "Inclacumab could indeed become an ...

An international team of authors from 17 institutions in seven countries, including the Woods Hole Research Center, published a study in the journal Nature Climate Change on the 10 March 2013 (10.1038/NCLIMATE1836: http://www.nature.com/nclimate). The study shows that, as the cover of snow and ice in the northern latitudes has diminished in recent years, the temperature over the northern land mass has increased at different rates during the four seasons, causing a reduction in temperature and vegetation seasonality in this area. The temperature and vegetation at northern ...

SAN DIEGO – A new study suggests that treatment with adrenocorticotropic hormone (ACTH) may be helpful for people whose multiple sclerosis (MS) is not well-controlled through their regular treatment. The study was released today and will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013. The study involved 23 people with MS who were taking beta-interferon treatment and had at least one relapse or brain scan showing new disease activity within the previous year. They were considered to have "breakthrough" MS, which ...

SAN DIEGO – The drug natalizumab is effective for treating multiple sclerosis (MS), but it increases the risk of a rare but potentially fatal brain infection called progressive multifocal leukoencephalopathy (PML). A study released today that will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013, suggests that early detection of PML may help improve survival and disability levels. The study examined 319 people with MS who were treated with natalizumab and diagnosed with PML. Because of the risk of PML, people ...

BOSTON—An international team of 21 authors from 17 institutions in seven countries has just published a study in the journal Natural Climate Change showing that, as the cover of snow and ice in the northern latitudes has diminished in recent years, the temperature over the northern land mass has increased at different rates during the four seasons, causing a reduction in temperature and vegetation seasonality in this area. In other words, the temperature and vegetation at northern latitudes increasingly resembles those found several degrees of latitude farther south as ...

Even though young athletes are required to receive health screens to be cleared to play sports, those tests failed to detect important cardiovascular abnormalities in cleared players, and many were allowed to play despite suspicions of dangerous cardiovascular conditions, according to a large registry study of patients who died from sudden death, being presented March 10 by Kevin Harris, MD, research cardiologist at the Minneapolis Heart Institute Foundation (MHIF). The data is being presented at the annual American College of Cardiology Scientific Sessions in San Francisco. ...

This press release is available in German. Protein activity is strictly regulated. Incorrect or poor protein regulation can lead to uncontrolled growth and thus cancer or chronic inflammation. Members of the Institute of Veterinary Biochemistry and Molecular Biology from the University of Zurich have identified enzymes that can regulate the activity of medically important proteins. Their discovery enables these proteins to be manipulated very selectively, opening up new treatment methods for inflammations and cancer. For a healthy organism, it is crucial for proteins ...

Tropical forests are less likely to lose biomass – plants and plant material - in response to greenhouse gas emissions over the twenty-first century than may previously have been thought, suggests a study published online this week in Nature Geoscience. In the most comprehensive assessment yet of the risk of tropical forest dieback due to climate change, the results have important implications for the future evolution of tropical rainforests including the role they play in the global climate system and carbon cycle. To remain effective, programmes such as the United ...

The risk of cardiovascular sudden death was very small and only about 30% of the incidence were due to diseases that could be reliably detected by pre-participation screening, even with 12-lead ECGs, according to research in a U.S. high school athlete population presented March 10 at the American College of Cardiology (ACC) Scientific Sessions. Sudden death in young competitive athletes due to cardiovascular disease is an important community issue, which could impact the design of population-based screening initiatives. The frequency with which these tragic events ...

Like nearly 4.6 million Americans, ancient hunter-gatherers also suffered from clogged arteries, revealing that the plaque build-up causing blood clots, heart attacks and strokes is not just a result of fatty diets or couch potato habits, according to new research in the journal The Lancet. The researchers performed CT scans of 137 mummies from across four continents and found artery plaque in every single population studied, from preagricultual hunter-gatherers in the Aleutian Islands to the ancient Puebloans of southwestern United States. Their findings provide an ...

EMBARGOED UNTIL 7:45 PM ET, Sunday, March 10, 2013, Cleveland: Researchers from Cleveland Clinic and Sweden-based Sahlgrenska University Hospital have found that a commonly used drug to treat anemia in heart failure patients –darbepoetin alfa – does not improve patients' health, nor does it reduce their risk of death from heart failure. Results of the international study were presented at the American College of Cardiology's annual meeting in San Francisco on March 10 and published simultaneously online by the New England Journal of Medicine. Initiated in 2006, the ...

PHILADELPHIA — A new immunoassay that tests for the presence of three biomarkers appears to be a valid screening method for the early detection of malignant kidney cancer, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. "Renal cell carcinoma, a malignant tumor arising from the kidney, is one of the most difficult forms of cancer to detect and treat properly because it remains silent until disseminating to other organs," said Nam Hoon Cho, M.D., of the Department of Pathology at Yonsei ...

Philadelphia, PA, March 11, 2013 – Once the initial episode of influenza has passed, the chronic effects tend to be overlooked. The results of a new study indicate that the cytokine interleukin-22 (IL-22) plays a critical role in normal lung repair following influenza infection. This study is published in the April 2013 issue of the American Journal of Pathology. "With the increasing prevalence of more infective and/or virulent strains of influenza, understanding the impact of virus on the host epithelium and the processes involved in lung repair are of great importance," ...

A new study has found that women who take aspirin have a reduced risk of developing melanoma—and that the longer they take it, the lower the risk. The findings suggest that aspirin's anti-inflammatory effects may help protect against this type of skin cancer. The study is published early online in CANCER, a peer-reviewed journal of the American Cancer Society. In the Women's Health Initiative, researchers observed US women aged 50 to 79 years for an average of 12 years and noted which individuals developed cancer. At the beginning of the study, the women were asked which ...

Check writer ezCheckPrinting software from halfpricesoft.com speeds up check printing and bill paying for thousands of small businesses. To simplify year-end tax reporting for users, the new version was released with the improved report feature. Users can now generate the report easily by date range, payee and category. ezCheckPrinting developers hope this new report will save users¡¯ time on year-end reporting. Writing a check is really easy with ezCheckPrinting! All user have to do is to enter the date, payee¡¯s name and amount payable to the payee. This check writer ...

Diane Calderaro has joined RE/MAX Alliance Group as a Broker-Associate in the Sarasota office. She has been a local real estate professional for 17 years, including a previous association with RE/MAX Alliance Group. Her market knowledge, strong negotiation skills and real estate expertise have consistently earned her recognition for customer satisfaction and sales performance, including the Multi-Million Dollar Producer Award from the Women's Council of Realtors in 2006, the WCI Communities Platinum level award in 2004 and 2005, and the Five Star Real Estate Agent Award ...