CORVALLIS, Ore. – Research at Oregon State University has found that one particular omega-3 fatty acid has a powerful effect in preventing liver inflammation and fibrosis – common problems that are steadily rising along with the number of Americans who are overweight. The American Liver Foundation has estimated that about 25 percent of the nation's population, and 75 percent of those who are obese, have nonalcoholic fatty liver disease. This early-stage health condition can sometimes progress to more serious, even fatal diseases, including nonalcoholic steatohepatitis, ...

It's no secret that fear is a mechanism often used in political campaigns to steer public opinion on hot-button issues like immigration and war. But not everyone is equally predisposed to be influenced by such a strategy, according to new research by Rose McDermott, professor of political science, and colleagues published in the American Journal of Political Science. By examining the different ways that fear manifests itself in individuals and its correlation to political attitudes, the researchers found that people who have a greater genetic liability to experience higher ...

A team of academic researchers has pinpointed how vitamin D3 and omega-3 fatty acids may enhance the immune system's ability to clear the brain of amyloid plaques, one of the hallmarks of Alzheimer's disease. In a small pilot study published in the Feb. 5 issue of the Journal of Alzheimer's Disease, the scientists identified key genes and signaling networks regulated by vitamin D3 and the omega-3 fatty acid DHA (docosahexaenoic acid) that may help control inflammation and improve plaque clearance. Previous laboratory work by the team helped clarify key mechanisms ...

West Orange, NJ. February 4, 2013. The final phase of the SCIRehab Project (Phase 3) was published in the November 2012 issue of the Journal of Spinal Cord Medicine (JSCM). Nine papers comprised the Special Issue: Relationship of Inpatient Rehabilitation Interventions to Outcomes Following Spinal Cord Injury. Guest editors: J. Scott Richards, Gale Whiteneck, Daniel Lammertse, Marcel Dijkers, and Julie Gassaway. Key article available for free download via ingentaconnect.com: Whiteneck G, Gassaway J. The SCIRehab Project: What rehabilitation interventions are most strongly ...

DURHAM, N.H. -- After three years of puzzling over a striking "ribbon" of energy and particles discovered by NASA's Interstellar Boundary Explorer (IBEX) at the edge of our solar system, scientists may be on the verge of cracking the mystery. In a paper published Feb. 4, 2013, in the Astrophysical Journal, researchers, including lead author Nathan Schwadron of the University of New Hampshire, propose a "retention theory" that for the first time explains all the key observations of this astrophysical enigma. "If the theory is correct," Schwadron notes, "the ribbon can ...

COLLEGE PARK, Md. – Humans survive by constantly recycling iron, a metal that is an essential component of red blood cells, but which is toxic outside of those cells. More than 90 percent of the iron in an adult human's 25 trillion life-sustaining red blood cells is recycled from worn-out cells. Almost 50 years ago scientists first began hypothesizing that our bodies must have a special protein 'container' to safely transport heme -- the form of iron found in living things – during the breakdown and recycling of old red blood cells and other types of heme metabolism. ...

1. Being Physically Fit Earlier in Life May Lower Risk for Dementia Later in Life Having a higher fitness level at midlife seems to be associated with lower hazards of developing Alzheimer disease and other types of dementia later in life. Between 1970 and 2009, researchers at a community health clinic utilized an exercise treadmill test to assess the baseline fitness levels of 19,458 non-elderly, community-dwelling adults who were in generally good health. The researchers reviewed Medicare data for the patients who became eligible to receive benefits between January ...

New York, NY—January 30, 2013—Researchers at Columbia Engineering and Georgia Institute of Technology have published a study in the online Early Edition of Proceedings of the National Academy of Sciences (PNAS) showing—for the first time—that certain volatile organic gases can promote cloud formation in a way never considered before by atmospheric scientists. The study will be published the week of February 4, 2013. "This is the first time gases have been shown to affect cloud formation in this way," says V. Faye McNeill, Associate Professor in Chemical Engineering at ...

Please cite the Bulletin of the Seismological Society of America (BSSA) as the source of this information. In the absence of long-term instrumental data, fragile rock formations, called hoodoos, may be key to understanding seismic hazard risk. In this study, researchers consider two hoodoos in Red Rock Canyon region to put limits on expected intensity of ground motion from earthquakes along the Garlock fault. Hoodoos can be found in desert regions and are highly susceptible to erosion that makes their age uncertain. Despite that uncertainty, existing unfractured hoodoos, ...

Please cite the Bulletin of the Seismological Society of America (BSSA) as the source of this information. The Osaka Basin, Japan is home to many high-rise buildings that sit atop its thick soft sediments, vulnerable to long-period strong ground motions that last minutes. A new map created by Japanese researchers is intended to guide engineers and city planners in new construction and identifies existing buildings with the potential of resonance vibration. The Osaka Basin in western Japan is surrounded by short mountain ranges, affected by large (M 8+) interplate earthquakes ...

Like a self-absorbed teenager, insects spend a lot of time grooming. In a study that delves into the mechanisms behind this common function, North Carolina State University researchers show that insect grooming – specifically, antennal cleaning – removes both environmental pollutants and chemicals produced by the insects themselves. The findings, published online this week in Proceedings of the National Academy of Sciences, show that grooming helps insects maintain acute olfactory senses that are responsible for a host of functions, including finding food, ...

STANFORD, Calif. - An antibody that binds to a molecule on the surface of a rare but deadly tumor of the gastrointestinal tract inhibits the growth of the cancer cells in mice, according to researchers at the Stanford University School of Medicine. The effect remains even when the cancer cells have become resistant to other treatments, and the findings may one day provide a glimmer of hope for people with the cancer, known as gastrointestinal stromal tumor, or GIST. The scientists hope to move into human clinical trials of the antibody within two years. The antibody's ...

LOS ANGELES — Medical scientists at the University of Southern California (USC) have bred a first-of-its-kind mouse model that possesses an immune response system more like a human's. The discovery makes way for quicker and more cost-effective development of next-generation drugs to treat human diseases like cancer, diabetes and tuberculosis. Medical researchers have long used mice and rats to help formulate new drugs and vaccines, in part because their genetic and biological characteristics closely parallel human physiology. But mice are not humans, and many experimental ...

STANFORD, Calif. — Stanford University School of Medicine investigators have identified a clutch of cells that — if seen in a male patient's blood after receiving a brand-new immune system in the form of a bone-marrow transplant from a female donor — herald the onset of chronic graft-versus-host disease, or cGVHD. In this devastating syndrome, the patient's tissues come under a vicious and enduring assault by the transplanted cells. "The overwhelming majority of patients who have these cells in their blood either have or will develop cGVHD within one to three months," ...

A team of researchers from Scotland has used a novel 3D printing technique to arrange human embryonic stem cells (hESCs) for the very first time. It is hoped that this breakthrough, which has been published today, 5 February, in the journal Biofabrication, will allow three-dimensional tissues and structures to be created using hESCs, which could, amongst other things, speed up and improve the process of drug testing. In the field of biofabrication, great advances have been made in recent years towards fabricating three-dimensional tissues and organs by combining artificial ...

PHILADELPHIA – Advance care directives allow patients to provide instructions about their preferences for the care they would like to receive if they develop an illness or a life-threatening injury and lose the capacity to make decisions for themselves. While many people may assume that patients have strong preferences for the type and aggressiveness of care they wish to receive near life's end, a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania suggests that for many patients, preferences for end-of-life care are constructed ...

CINCINNATI – Researchers have overcome a major challenge to treating brain diseases by engineering an experimental molecular therapy that crosses the blood-brain barrier to reverse neurological lysosomal storage disease in mice. Posted online in PNAS Early Edition on Feb. 4, the study was led by scientists at Cincinnati Children's Hospital Medical Center. "This study provides a non-invasive procedure that targets the blood-brain barrier and delivers large-molecule therapeutic agents to treat neurological lysosomal storage disorders," said Dao Pan, PhD, principal investigator ...

To predict whether a problem drinker will hit the bottle again, ignore what they say and watch their body language for displays of shame, a University of British Columbia study finds. The study, which explored drinking and health outcomes in newly sober recovering alcoholics, is the first to show that physical manifestations of shame – from slumped shoulders to narrow chests – can directly predict a relapse in people who struggle with substances. "Our study finds that how much shame people display can strongly predict not only whether they will go on to relapse, but ...

Healthy young men who watch TV for more than 20 hours a week have almost half the sperm count of men who watch very little TV, indicates a study published online in the British Journal of Sports Medicine. Conversely, men who do 15 or more hours of moderate to vigorous exercise every week have sperm counts that are 73% higher than those who exercise little, the findings show. Semen quality seems to have deteriorated over the past few decades, although it's not clear why, say the authors. To find out if an increasingly sedentary lifestyle might be a contributory ...

The theory that the last Neanderthals –Homo neanderthalensis– persisted in southern Iberia at the same time that modern humans –Homo sapiens– advanced in the northern part of the peninsula, has been widely accepted by the scientific community during the last twenty years. An international study, in which researchers of the Spanish National Distance Education University (UNED) participate, questions this hypothesis. "It is improbable that the last Neanderthals of central and southern Iberia would have persisted until such a late date, approximately 30,000 years ago, as ...

Mutations which affect the gene ASXL3 cause a novel syndrome similar to Bohring-Opitz syndrome, finds a study published in BioMed Central's open access journal Genome Medicine. This molecular definition distinguishes these children from those with Bohring-Opitz, and other similar syndromes, and highlights a technique able to help define rare diseases. When Dr Ropers from the Max-Planck Institute for Molecular Genetics in Berlin found a child with non-specific symptoms, including small size at birth, difficulties with movement and feeding, severe intellectual disability, ...

Researchers at Imperial College London have discovered a new way in which a very common childhood disease could be treated. In the first year of life, 65 per cent of babies get infected by Respiratory Syncytial Virus (RSV). This causes bronchiolitis, and is thought to kill nearly 200,000 children every year worldwide. In 1966 and 1967, vaccines were tested for RSV. These had disastrous effects on the immune response, leading to a worsening of the disease and, in many cases, death. Scientists have so far not been able to fully explain this effect, which continues to ...

A chance discovery that sea urchins use Nickel ions to harness carbon dioxide from the sea to grow their exoskeleton could be the key to capturing tonnes of CO2 from the atmosphere. Experts at Newcastle University, UK, have discovered that in the presence of a Nickel catalyst, CO2 can be converted rapidly and cheaply into the harmless, solid mineral, calcium or magnesium carbonate. This discovery, which is published today in the academic journal Catalysis Science & Technology, has the potential to revolutionise the way we capture and store carbon enabling us to significantly ...

A group of recipients of cadaver-derived human growth hormone (c-hGH) does not appear to be at increased risk for Alzheimer and Parkinson disease despite their likely exposure to neurodegenerative disease (ND)-associated proteins and elevated risk of infectious prion protein-related disease, according to a report published Online First by JAMA Neurology, a JAMA Network publication. David J. Irwin, M.D., of the University of Pennsylvania Perelman School of Medicine, Philadelphia, and colleagues looked for evidence for human-to-human transmission of Alzheimer disease (AD), ...

Preliminary evidence from a clinical trial suggests that treatment with glucagon-like peptide-1 (GLP-1) receptor agonists was associated with reduced body mass index and body weight in adolescents with severe obesity, according to a report published Online First by JAMA Pediatrics, a JAMA Network publication. GLP-1 receptor agonist therapy, approved for adults with type 2 diabetes mellitus, reduces body weight by enhancing satiety and suppressing appetite, even in patients without diabetes, according to the study background. Aaron S. Kelly, Ph.D., of the University ...