Gene linked to respiratory distress in babies
2012-11-27
Some infants are more susceptible to potentially life-threatening breathing problems after birth, and rare, inherited DNA differences may explain why, according to research at Washington University School of Medicine in St. Louis.
The study is the first to identify a single gene — ABCA3 — that is associated with a significant number of cases of respiratory distress syndrome (RDS) in babies born at or near full term. RDS is the most common respiratory problem in newborns and the most common lung-related cause of death and disease among U.S. infants less than a year old.
Their ...
The installed price of solar photovoltaic systems in the US continues to decline at a rapid pace
2012-11-27
Berkeley, CA — The installed price of solar photovoltaic (PV) power systems in the United States fell substantially in 2011 and through the first half of 2012, according to the latest edition of Tracking the Sun, an annual PV cost-tracking report produced by the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab).
The median installed price of residential and commercial PV systems completed in 2011 fell by roughly 11 to 14 percent from the year before, depending on system size, and, in California, prices fell by an additional 3 to 7 percent within ...
Topical simvastatin shown to accelerate wound healing in diabetes
2012-11-27
Philadelphia, PA, November 27, 2012 – Delayed wound healing is a major complication of diabetes because the physiological changes in tissues and cells impair the wound healing process. This can result in additional disease outcomes such as diabetic foot ulcer, a significant cause of morbidity in the growing population of diabetic patients. A new study has found that topically applied simvastatin accelerates wound healing in diabetic mice, suggesting important implications for humans with diabetes. This study is published in the December issue of The American Journal of ...
Amyloid imaging helps in evaluating possible Alzheimer disease
2012-11-27
Philadelphia, Pa. (November 27, 2012) – A test to detect brain amyloid deposits associated with Alzheimer disease (AD) provides doctors with useful information on treatment and further testing for patients with cognitive impairment, according to a study published online by the journal Alzheimer Disease & Associated Disorders. The journal is published by Lippincott Williams & Wilkins, a part ofWolters Kluwer Health.
Positron emission tomography (PET) scans using a biomarker called florbetapir F18 can show amyloid plaques in the brain—a characteristic feature of AD. ...
What keeps a cell's energy source going
2012-11-27
PHILADELPHIA — Most healthy cells rely on a complicated process to produce the fuel ATP. Knowing how ATP is produced by the cell's energy storehouse – the mitochondria -- is important for understanding a cell's normal state, as well as what happens when things go wrong, for example in cancer, cardiovascular disease, neurodegeneration, and many rare disorders of the mitochondria.
Two years ago, Kevin Foskett, PhD, professor of Physiology at the Perelman School of Medicine, University of Pennsylvania, and colleagues discovered that fundamental control of ATP production ...
New review associates vitamin D with lower rates of tooth decay
2012-11-27
A new review of existing studies points toward a potential role for vitamin D in helping to prevent dental caries, or tooth decay.
The review, published in the December issue of Nutrition Reviews, encompassed 24 controlled clinical trials, spanning the 1920s to the 1980s, on approximately 3,000 children in several countries. These trials showed that vitamin D was associated with an approximately 50 percent reduction in the incidence of tooth decay.
"My main goal was to summarize the clinical trial database so that we could take a fresh look at this vitamin D question," ...
West coast log exports up slightly in third quarter of 2012
2012-11-27
Log exports from Washington, Oregon, northern California, and Alaska increased about nine percent in the third quarter of 2012, totaling 412 million board feet, according to the U.S. Forest Service's Pacific Northwest Research Station. At the same time, lumber exports decreased about eight percent to 186 million board feet, compared to the second quarter of this year.
"Sixty-two percent of West coast log exports went to China during the third quarter," said Xiaoping Zhou, a research economist with the station who compiled the data. "China increased its importation of ...
Annals of Internal Medicine tip sheet for 27 Nov. 2012
2012-11-27
1. Task Force Reviews Evidence to Update Hepatitis C Screening Recommendations for Asymptomatic Adults
In 2004, the United States Preventive Services Task Force recommended against routine screening for hepatitis C virus (HCV) infection in asymptomatic adults who are not at increased risk for infection. At the time, the Task Force also found insufficient evidence to recommend for or against routine HCV screening for adults at high risk for infection. Since then, other groups have recommended screening higher-risk patients, including a recommendation by the Centers for ...
USC/CHLA research shows autism risk for developing children exposed to air pollution
2012-11-27
LOS ANGELES — Research conducted by University of Southern California (USC) and Children's Hospital Los Angeles scientists demonstrates that polluted air – whether regional pollution or coming from local traffic sources – is associated with autism.
The study titled "Traffic Related Air Pollution, Particulate Matter, and Autism," shows that exposure to traffic-related air pollution during pregnancy and the first year of life is associated with a more than two-fold risk of autism. In addition, exposure to regional pollution consisting of nitrogen dioxide (NO2) and small ...
Evolutionary mode routinely varies amongst morphological traits within fossil species lineages
2012-11-27
What happens when the modern evolutionary theory of punctuated equilibrium collides with the older theory of mosaic evolution? Part of the answer comes from a new, wide-ranging study by paleobiologists Melanie J Hopkins at the Museum fuer Naturkunde Berlin and Scott Lidgard at the Field Museum in Chicago. Their results are published this week in the Proceedings of the National Academy of Sciences (PNAS).
While processes of evolution are largely studied by observation and experiment in the living world, evolutionary tempo and mode – rates and patterns of change, respectively ...
Preventive screening for sudden cardiac death in young athletes debated
2012-11-27
While ensuring the safety of high school and college athletes is hardly controversial, the method and associated costs of doing so are hotly debated. Conducting electrocardiographic (ECG) screenings of all young competitive athletes in the United States would cost up to $69 billion over 20 years and save about 4,813 lives, making the cost per life saved over $10 million, according to a study published online today in the Journal of the American College of Cardiology.
A corresponding editorial suggests that this number is inflated and "misleading" and blames the high ...
Exposure to traffic pollution in pregnancy, first year of life appears associated with autism
2012-11-27
CHICAGO – Exposure to traffic-related air pollution, particulate matter and nitrogen dioxide during pregnancy and during the first year of a child's life appears to be associated with an increased risk of autism, according to a report published Online First by Archives of General Psychiatry, a JAMA Network publication.
Autism is a diverse disorder with genetic and environmental factors likely contributing to its origins. Autism spectrum disorders are commonly characterized by problems in communication, social interaction and repetitive behaviors. Emerging evidence suggests ...
Study suggests eliminating Medicare consultation payments associated with a net increase in spending
2012-11-27
CHICAGO – A study of Medicare claims data suggests that eliminating payments for consultations commonly billed by specialists was associated with a net increase in spending on visits to both primary care physicians and specialists, according to a report published Online First by Archives of Internal Medicine, a JAMA Network publication.
Before 2010, Medicare payments for consultations were substantially higher than for office visits of similar complexity that were commonly billed by primary care physicians (PCPs). In January 2010, Medicare eliminated consultation payments ...
Automated phone and mail notices increase medication adherence
2012-11-27
PASADENA, Calif., Nov. 26, 2012 — Patients newly prescribed a cholesterol-lowering medication were more likely to pick it up from the pharmacy if they received automated phone and mail reminders, according to a study published in the Archives of Internal Medicine today. This is one of a few published studies to examine strategies for reducing primary nonadherence, which occurs when patients do not pick up new prescriptions.
The study of 5,216 Kaiser Permanente Southern California patients found that those who received an automated reminder were 1.6 times more likely ...
Shrubs lend an insight into a glacier's past
2012-11-27
The stems of shrubs have given researchers a window into a glacier's past, potentially allowing them to more accurately assess how they're set to change in the future.
Their findings have been published today, 27 November, in IOP Publishing's journal Environmental Research Letters, and show how a glacier's history of melting can be extended way past the instrumental record.
Much like the rings on a tree stump indicate how old it is, measuring the width of rings on the stem of a shrub can give a good indication of how well it has grown year on year. Under extreme environmental ...
Scientists image brain structures that deteriorate in Parkinson's
2012-11-27
CAMBRIDGE, MA -- A new imaging technique developed at MIT offers the first glimpse of the degeneration of two brain structures affected by Parkinson's disease.
The technique, which combines several types of magnetic resonance imaging (MRI), could allow doctors to better monitor patients' progression and track the effectiveness of potential new treatments, says Suzanne Corkin, MIT professor emerita of neuroscience and leader of the research team. The first author of the paper is David Ziegler, who received his PhD in brain and cognitive sciences from MIT in 2011.
The ...
Using biomarkers from prehistoric human feces to track settlement and agriculture
2012-11-27
For researchers who study Earth's past environment, disentangling the effects of climate change from those related to human activities is a major challenge, but now University of Massachusetts Amherst geoscientists have used a biomarker from human feces in a completely new way to establish the first human presence, the arrival of grazing animals and human population dynamics in a landscape.
Doctoral student Robert D'Anjou and his advisor Raymond Bradley, director of the Climate System Research Center at UMass Amherst, with UMass colleagues Nick Balascio and David Finkelstein, ...
This week's forecast: Sunny with a 40 percent chance of flu
2012-11-27
NEW YORK (November 26, 2012)—Scientists have developed a system to predict the timing and severity of seasonal influenza outbreaks that could one day help health officials and the general public better prepare for them. The system adapts techniques used in modern weather prediction to turn real-time, Web-based estimates of influenza infection into local forecasts of seasonal flu.
Results appear online in the Proceedings of the National Academy of Sciences.
Year to year, and region to region, there is huge variability in the peak of flu season, which, in temperate areas ...
New hope for setback-dogged cancer treatment
2012-11-27
Several drugs companies have ineffectively tried to produce antibodies that bind to the IGF-1 receptor on the cell surface, which has a critical part to play in the development of cancer. Scientists at Karolinska Institutet in Sweden have now ascertained how these antibodies work, and can explain why only some cancer patients are helped by IGF-1 blockers during clinical tests. The researchers also present a means by which drugs of this kind could help more cancer patients.
Every cell contains thousands of tiny receptors that help it communicate with other cells. These ...
Ancient microbes found living beneath the icy surface of Antarctic lake
2012-11-27
RENO – This week a pioneering study published in the Proceedings of the National Academy of Sciences (PNAS) and co-authored by Dr. Alison Murray and Dr. Christian Fritsen of Nevada's Desert Research Institute (DRI) reveals, for the first time, a viable community of bacteria that survives and ekes out a living in a dark, salty and subfreezing environment beneath nearly 20 meters of ice in one of Antarctica's most isolated lakes.
Lake Vida, the largest of several unique lakes found in the McMurdo Dry Valleys, contains no oxygen, is mostly frozen and possesses the highest ...
Possible new treatment for Ewing sarcoma
2012-11-27
SALT LAKE CITY— Discovery of a new drug with high potential to treat Ewing sarcoma, an often deadly cancer of children and young adults, and the previously unknown mechanism behind it, come hand-in-hand in a new study by researchers from Huntsman Cancer Institute (HCI) at the University of Utah. The report appears in today's online issue of the journal Oncogene.
"Ewing sarcoma is almost always caused by a cancer-causing protein called EWS/FLI," said Stephen Lessnick, M.D., Ph.D., director of HCI's Center for Children's Cancer Research, professor in the Department of ...
Bioengineered marine algae expands environments where biofuels can be produced
2012-11-27
Biologists at UC San Diego have demonstrated for the first time that marine algae can be just as capable as fresh water algae in producing biofuels.
The scientists genetically engineered marine algae to produce five different kinds of industrially important enzymes and say the same process they used could be employed to enhance the yield of petroleum-like compounds from these salt water algae. Their achievement is detailed in a paper published online in the current issue of the scientific journal Algal Research.
The ability to genetically transform marine algae into ...
Students at cooperative schools are more engaged
2012-11-27
This press release is available in Spanish.
Student engagement is not independent of the type of school attended.Nor is it independent of the organisational development of the school.The school's organisational style affects the work of its teaching staff, which, in turn, has repercussions on the performance and engagement of their students.As IkerRos, the UPV/EHU researcher, has been able to verify in his PhD thesis, these factors vary when comparing public schools, subsidised schools and co-operative schools, the latter being the ones that fare best.
"The study of ...
Dramatic rise in autism prevalence parallels research explosion
2012-11-27
(NEW YORK, N.Y., November 26, 2012) – Autism Speaks Chief Science Officer Geraldine Dawson, Ph.D. describes how the dramatic progress in autism research has paralleled increased recognition of autism's prevalence and financial impact in the December issue of the Archives of General Psychiatry published on line today. "This issue of the journal features three articles on autism," she writes in her editorial. "A decade ago, the journal published about the same number of autism articles per year."
Dr. Dawson also notes that, while the funding for autism research has dramatically ...
University of Maryland School of Medicine, NIH study pinpoints brain area's role in learning
2012-11-27
An area of the brain called the orbitofrontal cortex is responsible for decisions made on the spur of the moment, but not those made based on prior experience or habit, according to a new basic science study from substance abuse researchers at the University of Maryland School of Medicine and the National Institute on Drug Abuse (NIDA). Scientists had previously believed that the area of the brain was responsible for both types of behavior and decision-making. The distinction is critical to understanding the neurobiology of decision-making, particularly with regard to substance ...
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