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Child's home address helps predict risk of readmission to hospital

2012-10-19
Simply knowing a child's home address and some socioeconomic data can serve as a vital sign – helping hospitals predict which children admitted for asthma treatment are at greater risk for re-hospitalization or additional emergency room visits, according to new research in the American Journal of Public Health. The use of a so-called "geographic social risk index," based on census measures of poverty, home values and number of adults with high school degrees, also can help hospitals identify families likely to report financial or psychological hardship – both of which ...

Tropical collapse caused by lethal heat

2012-10-19
Scientists have discovered why the 'broken world' following the worst extinction of all time lasted so long – it was simply too hot to survive. The end-Permian mass extinction, which occurred around 250 million years ago in the pre-dinosaur era, wiped out nearly all the world's species. Typically, a mass extinction is followed by a 'dead zone' during which new species are not seen for tens of thousands of years. In this case, the dead zone, during the Early Triassic period which followed, lasted for a perplexingly long period: five million years. A study jointly led ...

Low calcium diet linked to higher risk of hormone condition in women

2012-10-19
Primary hyperparathyroidism or PHPT is caused by overactive parathyroid glands secreting too much parathyroid hormone, which can result in weak bones, fractures and kidney stones. In recent years, several studies have also suggested a link between untreated PHPT and an increased risk of high blood pressure, heart attack and stroke. PHPT affects one in 800 people during their lifetime. It is most common in post-menopausal women between 50-60 years of age. Calcium intake is known to influence parathyroid hormone production and therefore may be important in the development ...

Blood hormone levels can predict long-term breast cancer risk

2012-10-19
BOSTON, MA—Blood hormone tests can predict a woman's risk for developing postmenopausal breast cancer for up to 20 years, according to a study led by Xuehong Zhang, MD, Channing Division of Network Medicine, Brigham and Women's Hospital (BWH) Department of Medicine. The findings will be presented at the 11th Annual American Association for Cancer Research (AACR) International Conference on Frontiers in Cancer Prevention Research. Using data from the Nurses' Health Study, Zhang , Susan Hankinson, ScD, Channing Division of Network Medicine, BWH Department of Medicine ...

Living in ethnically homogenous area boosts health of minority seniors

2012-10-19
An African-American or Mexican-American senior living in a community where many neighbors share their background is less likely to have cancer or heart disease than their counterpart in a more mixed neighborhood. Results of the new study by Kimberly Alvarez, a PhD student at Columbia University's Mailman School of Public Health, and Becca Levy, PhD, associate professor of Epidemiology and Psychology at the Yale School of Public Health, appear in the December issue of the American Journal of Public Health and online. Counter to prevailing notions, researchers found ...

Stroke patients benefit from carmaker's efficiency

Stroke patients benefit from carmakers efficiency
2012-10-19
A process developed to increase efficiency and productivity in Japanese car factories has helped improve stroke treatment at Barnes-Jewish Hospital, report researchers at Washington University School of Medicine in St. Louis. By applying the principles of Toyota's lean manufacturing process, doctors sharply reduced the average time between patient arrival and treatment, known as door-to-needle time, from 58 to 37 minutes. The findings are reported Oct. 18 in the journal Stroke. In an average year, the medical school's physicians treat 1,300 stroke patients at Barnes-Jewish. Beginning ...

No antibodies, no problem

2012-10-19
Researchers at the Johns Hopkins Bloomberg School of Public Health have determined a new mechanism by which the mosquitoes' immune system can respond with specificity to infections with various pathogens, including the parasite that causes malaria in humans, using one single gene. Unlike humans and other animals, insects do not make antibodies to target specific infections. According to the Johns Hopkins researchers, mosquitoes use a mechanism known as alternative splicing to arrange different combinations of binding domains, encoded by the same AgDscam gene, into protein ...

Study shows breastfeeding reduced risk for ER/PR-negative breast cancer

2012-10-19
October 18, 2012 -- Breast-feeding reduces the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to a study conducted at Columbia University's Mailman School of Public Health. Researchers examined the association between reproductive risk factors — such as the number of children a woman delivers, breast-feeding and oral contraceptive use – and found an increased risk for estrogen receptor- and progesterone receptor- (ER/PR) negative breast cancer in women who do not breast-feed. The results also indicated that having three ...

Study shows elevated risk of blood clots in women taking birth control containing drospirenone

2012-10-19
OAKLAND, Calif., Oct. 18— A U.S. Food and Drug Administration-funded study led by the Kaiser Permanente Northern California Division of Research found an increased risk of arterial thrombotic events (ATE) and venous thromboembolic events (VTE) — commonly referred to as blockage of arteries and blood clots, respectively — associated with drospirenone-containing birth control pills compared to four low-dose estrogen combined hormonal contraceptives. The study appears in the current online issue of Contraception. "We found that starting use of drospirenone-containing combined ...

Caltech modeling feat sheds light on protein channel's function

Caltech modeling feat sheds light on protein channels function
2012-10-19
PASADENA, Calif.—Chemists at the California Institute of Technology (Caltech) have managed, for the first time, to simulate the biological function of a channel called the Sec translocon, which allows specific proteins to pass through membranes. The feat required bridging timescales from the realm of nanoseconds all the way up to full minutes, exceeding the scope of earlier simulation efforts by more than six orders of magnitude. The result is a detailed molecular understanding of how the translocon works. Modeling behavior across very different timescales is a major ...

Depression, shortened telomeres increase mortality in bladder cancer patients

2012-10-19
HOUSTON - Low depressive symptoms and a longer telomere length are compelling factors that contribute to a prolonged life for bladder cancer patients according to researchers at The University of Texas MD Anderson Cancer Center. In an observational study, a team of MD Anderson researchers analyzed clinical and behavioral data collected from 464 bladder cancer patients, according to research presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research. "This is the first study of its kind that analyzes bladder cancer outcomes," ...

Bicycle infrastructure can reduce risk of cycling injuries by half: UBC study

2012-10-19
Certain types of routes carry much lower risk of injury for cyclists, according to a new University of British Columbia study on the eve of Vancouver's Bike to Work Week. The study, published today in the American Journal of Public Health, analyzed the cause of 690 cycling injuries in Vancouver and Toronto from 2008 to 2009 and various route types and infrastructure. The greatest risk to cyclists occurs when they share major streets with parked cars, with no bike lanes present – like on Broadway in Vancouver or Dundas Street in Toronto. Without a designated space on ...

AMP reports on possibilities, challenges, and applications of next-generation sequencing

2012-10-19
Bethesda, MD, October 18, 2012 The Association for Molecular Pathology (AMP) published the report of the Whole Genome Analysis (WGA) Working Group of the AMP Clinical Practice Committee in the November 2012 issue of The Journal of Molecular Diagnostics (JMD). Titled "Opportunities and Challenges Associated with Clinical Diagnostic Genome Sequencing," the timely report provides a detailed and compelling overview of the landscape of next generation sequencing (NGS) technology and its clinical relevance and impact on improving patient care. The issues addressed in the ...

First-of-its-kind self-assembled nanoparticle for targeted and triggered thermo-chemotherapy

2012-10-19
Boston, MA— Excitement around the potential for targeted nanoparticles (NPs) that can be controlled by stimulus outside of the body for cancer therapy has been growing over the past few years. More specifically, there has been considerable attention around near-infrared (NIR) light as an ideal method to stimulate nanoparticles from outside the body. NIR is minimally absorbed by skin and tissue, has the ability to penetrate deep tissue in a noninvasive way and the energy from NIR light can be converted to heat by gold nanomaterials for effective thermal ablation of diseased ...

Conservation scientists look beyond greenbelts to connect wildlife sanctuaries

Conservation scientists look beyond greenbelts to connect wildlife sanctuaries
2012-10-19
We live in a human-dominated world. For many of our fellow creatures, this means a fragmented world, as human conduits to friends, family, and resources sever corridors that link the natural world. Our expanding web of highways, cities, and intensive agriculture traps many animals and plants in islands and cul-de-sacs of habitat, held back by barriers of geography or architecture from reaching mates, food, and wider resources. A team of researchers, managers, and ecological risk assessors review the current state-of-the-art in landscape connectivity planning, offering ...

Solar power is contagious

2012-10-19
People are more likely to install a solar panel on their home if their neighbors have one, according to a Yale and New York University study in the journal Marketing Science. The researchers studied clusters of solar installations throughout California from January 2001 to December 2011 and found that residents of a particular zip code are more likely to install solar panels if they already exist in that zip code and on their street. "We looked at the influence that the number of cumulative adoptions—the number of people who already installed solar panels in a zip ...

Helmet-to-helmet collisions: Scientists model how vibrations from football hits wobble the brain

2012-10-19
It's fall football season, when fight songs and shouted play calls fill stadiums across the country. Another less rousing sound sometimes accompanies football games: the sharp crack of helmet-to-helmet collisions. Hard collisions can lead to player concussions, but the physics of how the impact of a helmet hit transfers to the brain are not well understood. A research team from the U.S. Naval Academy in Annapolis, Md., has created a simplified experimental model of the brain and skull inside a helmet during a helmet-to-helmet collision. The model illustrates how the fast ...

Dinosaur-era acoustics: Global warming may give oceans the 'sound' of the Cretaceous

2012-10-19
Global temperatures directly affect the acidity of the ocean, which in turn changes the acoustical properties of sea water. New research suggests that global warming may give Earth's oceans the same hi-fi sound qualities they had more than 100 million years ago, during the Age of the Dinosaurs. The reason for this surprising communication upgrade is that whales vocalize in the low-frequency sound range, typically less than 200 hertz, and the new research predicts that by the year 2100, global warming will acidify saltwater sufficiently to make low-frequency sound near ...

Short booms still annoying: Scientists study how mid-level noise bursts lasting less than a second affect the concentration of arithmetic-solving test subjects

2012-10-19
Noise can be distracting, especially to a person trying to concentrate on a difficult task. Studying annoying noises helps architects design better building environments and policy makers choose effective noise regulations. To better understand how short noise bursts affect humans' mental state, researchers from the University of Nebraska – Lincoln played quarter-second-long white noise clips to test subjects as they worked on arithmetic problems. The researchers noticed a slight general trend toward lower performance when louder noises were played, and also identified ...

Taking the bite out of baseball bats

2012-10-19
Miss hitting the "sweet spot" on a baseball bat and the resulting vibrations can zing your hands. Bat companies have tried for decades to reduce these painful shocks with limited success. But Daniel Russell, a professor in the graduate program in acoustics at Pennsylvania State University in University Park, has figured out that bat vibrations between 600 and 700 hertz (Hz) cause the most pain and that specifically tuned vibration absorbers are the best at combatting the sting. He will present the results of his damping technique comparisons at the 164th meeting of the ...

World's largest subwoofer: Earthquakes 'pump' ground to produce infrasound

2012-10-19
Earthquakes sway buildings, buckle terrain, and rumble – both audibly and in infrasound, frequencies below the threshold of human hearing. New computer modeling by a team of researchers indicates that most of the low-frequency infrasound comes from an unexpected source: the actual "pumping" of the Earth's surface. The researchers confirmed their models by studying data from an actual earthquake. "It's basically like a loudspeaker," said Stephen Arrowsmith, a researcher with the Geophysics Group at Los Alamos National Laboratory in Santa Fe, N.M., who presents his team's ...

NASA pursues atom optics to detect the imperceptible

NASA pursues atom optics to detect the imperceptible
2012-10-19
VIDEO: Einstein predicted gravity waves in his general theory of relativity, but to date these ripples in the fabric of space-time have never been observed. Now a scientific research technique called... Click here for more information. A pioneering technology capable of atomic-level precision is now being developed to detect what so far has remained imperceptible: gravitational waves or ripples in space-time caused by cataclysmic events including even the Big Bang itself. A ...

NASA sees strong wind shear adversely affect Tropical Storm Maria

NASA sees strong wind shear adversely affect Tropical Storm Maria
2012-10-19
Tropical Storm Maria is moving away from Japan and strong wind shear is pushing its rainfall east of the storm's center, according to NASA satellite imagery. On Oct. 18 at 0845 UTC (4:45 a.m. EDT), NASA's Tropical Rainfall Measuring Mission (TRMM) satellite saw that rain associated with Tropical Storm Maria was limited to the east of the storm's center. Rainfall was also light to moderate, falling at a rate between .78 to 1.57 inches/20 to 40 mm per hour. There were no areas of heavy rain remaining in the tropical cyclone. The low-level center of the storm is now exposed ...

Poetry in motion: Gemini Observatory releases image of rare polar ring galaxy

Poetry in motion: Gemini Observatory releases image of rare polar ring galaxy
2012-10-19
When the lamp is shattered, The light in the dust lies dead. When the cloud is scattered, The rainbow's glory is shed. These words, which open Shelley's poem "When the Lamp is Shattered," employ visions of nature to symbolize life in decay and rebirth. It's as if he had somehow foreseen the creation of this new Gemini Legacy image, and penned a caption for it. What Gemini has captured is nothing short of poetry in motion: the colorful and dramatic tale of a life-and-death struggle between two galaxies interacting. All the action appears in a single frame, with the ...

NASA's TRMM satellite sees very heavy rains in fading Tropical Storm Prapiroon

NASAs TRMM satellite sees very heavy rains in fading Tropical Storm Prapiroon
2012-10-19
Heavy rainfall returned to Typhoon Prapiroon for a brief time on Oct. 18 when NASA's TRMM satellite passed overhead. Prapiroon is battling strong wind shear and is expected to transition into an extra-tropical storm in the next day. NASA's Tropical Rainfall Measuring Mission (TRMM) satellite captured rainfall data on Prapiroon twice on Oct. 18 when it passed overhead. The first orbit was at 0845UTC and the second at 1019 UTC. TRMM's Microwave Imager (TMI) and Precipitation Radar (PR) data show that rain associated with Prapiroon was falling at a rate of over 75mm/hour ...
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