Why a hereditary anemia is caused by genetic mutation in mechanically sensitive ion channel
BUFFALO, N.Y. – A genetic mutation that alters the kinetics of an ion channel in red blood cells has been identified as the cause behind a hereditary anemia, according to a paper (http://bit.ly/13LgCzc) published this month in the Proceedings of the National Academy of Sciences by University at Buffalo scientists and colleagues.
The research team was led by Frederick Sachs, PhD, SUNY Distinguished Professor in the UB Department of Physiology and Biophysics, who discovered in the 1980s that some ion channels are mechanosensitive, that is, they convert mechanical stress ...


