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Mayo Clinic begins to unravel rare heart condition that strikes young, healthy women

2012-07-17
ROCHESTER, Minn. -- Spontaneous coronary artery dissection (SCAD), a tear of the layers of the artery wall that can block normal blood flow into and around the heart, is a relatively rare and poorly understood condition. It often strikes young, otherwise healthy people -- mostly women -- and can lead to significant heart damage, even sudden death. Now, in the first study of its kind of such patients, Mayo Clinic researchers have started to uncover important clues about SCAD, including its potential risk factors, optimal treatment approaches and short- and long-term cardiovascular ...

US Army: Pre-injury cartilage biomarkers associated with subsequent ACL injuries

2012-07-17
Baltimore, Md., July 16, 2012 – U.S. Army researchers made a surprising discovery while examining the impact of an anterior cruciate ligament (ACL) tear (a common knee injury), on four serum biomarkers associated with cartilage health. The researchers found that pre-injury concentrations for all but one of the four serum biomarkers studied were associated with the subsequent likelihood of ACL injury. The findings were presented Saturday at the annual meeting of the American Orthopaedic Society for Sports Medicine (AOSSM). "We expected to see post-injury differences in ...

Increase in RDA for vitamin C could help reduce heart disease, stroke, cancer

2012-07-17
CORVALLIS, Ore. – The recommended dietary allowance, or RDA, of vitamin C is less than half what it should be, scientists argue in a recent report, because medical experts insist on evaluating this natural, but critical nutrient in the same way they do pharmaceutical drugs and reach faulty conclusions as a result. The researchers, in Critical Reviews in Food Science and Nutrition, say there's compelling evidence that the RDA of vitamin C should be raised to 200 milligrams per day for adults, up from its current levels in the United States of 75 milligrams for women and ...

RIH study: Emergency patients prefer technology-based interventions for behavioral issues

2012-07-17
PROVIDENCE, R.I. – A Rhode Island Hospital researcher has found that emergency department patients prefer technology-based interventions for high-risk behaviors such as alcohol use, unsafe sex and violence. ER patients said they would choose technology (ie text messaging, email, or Internet) over traditional intervention methods such as in-person or brochure-based behavioral interventions. The paper by Megan L. Ranney, M.D., is available now online in advance of print in the Annals of Emergency Medicine. The study was a cross-sectional survey of urban emergency department ...

Uncommon BRAF mutation in melanoma sensitive to MEK inhibitor drug therapy

2012-07-17
An uncommon mutation of the BRAF gene in melanoma patients has been found to respond to MEK inhibitor drugs, providing a rationale for routine screening and therapy in melanoma patients who harbor the BRAF L597 mutation. The new study by co-first-authors Kimberly Brown Dahlman, Ph.D., Junfeng Xia, Ph.D., and Katherine Hutchinson, B.S., Vanderbilt-Ingram Cancer Center (VICC), Nashville, Tenn., was published online July 14 in Cancer Discovery. The research was led by co-senior authors William Pao, M.D., Ph.D., Jeffrey Sosman, M.D., and Zhongming Zhao, Ph.D., VICC, and ...

Low-cal diet's effects seen in fly brain, mouthpart

2012-07-17
SAN ANTONIO (July 16, 2012) — A novel technique for measuring tiny, rapid-fire secretions in the brains and mouthparts of fruit flies (drosophila) is providing insights into the beneficial effects of eating less — information that ultimately could help people suffering from neuromuscular disorders. Using the method, researchers uncovered never-before-seen brain chemistry that helps explain why fruit flies genetically manipulated to mimic conditions such as Parkinson's disease and myasthenia gravis are more vigorous and live longer when fed a restricted diet. Published ...

Gene therapy treatment extends lives of mice with fatal disease, MU study finds

2012-07-17
COLUMBIA, Mo. — A team of University of Missouri researchers has found that introducing a missing gene into the central nervous system could help extend the lives of patients with Spinal Muscular Atrophy (SMA) – the leading genetic cause of infantile death in the world. SMA is a rare genetic disease that is inherited by one in 6,000 children who often die young because there is no cure. Children who inherit SMA are missing a gene that produces a protein which directs nerves in the spine to give commands to muscles. The MU team, led by Christian Lorson, professor in ...

U of S researchers discover cannabis 'pharma factory'

2012-07-17
U of S researchers have discovered the chemical pathway that Cannabis sativa uses to create bioactive compounds called cannabinoids, paving the way for the development of marijuana varieties to produce pharmaceuticals or cannabinoid-free industrial hemp. The research appears online in the July 16 early edition of the Proceedings of the National Academy of Sciences (PNAS). U of S adjunct professor of biology Jon Page explains that the pathway is an unusual one, involving a specialized version of one enzyme, called hexanoyl-CoA synthetase, and another enzyme, called olivetolic ...

Victory stance may be a universal gesture of triumph -- not pride -- study suggests

2012-07-17
When Olympic athletes throw up their arms, clench their fists and grimace after a win, they are displaying triumph through a gesture that is the same across cultures, a new study suggests. New findings due to be published in the journal Evolution and Human Behavior suggest this victory pose signals feelings of triumph, challenging previous research that labeled the expression pride. "We found that displays of triumph include different behaviors to those of pride and occur more immediately after a victory or win," said David Matsumoto, professor of psychology at San Francisco ...

Weight loss today keeps the doctor away

2012-07-17
Montreal, July 16, 2012 – Statistics show that today, almost one in four Canadians is obese. A deadly trend that has been on the rise for the last thirty years, obesity is associated with diabetes, heart disease and cancer. But is the obesity epidemic putting more pressure on an already strained Canadian health care system? James McIntosh, a professor in the Department of Economics at Concordia University, is the first to look at the impact of obesity on the number of doctor visits nation-wide. According to his research, obese individuals visit the doctor more frequently ...

Neurons derived from cord blood cells may represent new therapeutic option

2012-07-17
LA JOLLA, CA----For more than 20 years, doctors have been using cells from blood that remains in the placenta and umbilical cord after childbirth to treat a variety of illnesses, from cancer and immune disorders to blood and metabolic diseases. Now, scientists at the Salk Institute for Biological Studies have found a new way-using a single protein, known as a transcription factor-to convert cord blood (CB) cells into neuron-like cells that may prove valuable for the treatment of a wide range of neurological conditions, including stroke, traumatic brain injury and spinal ...

AGU Journal highlights -- July 16

2012-07-17
The following highlights summarize research papers that have been recently published in Journal of Geophysical Research-Biogeosciences (JGR-G), Journal of Geophysical Research-Atmospheres (JGR-D), Journal of Geophysical Research-Planets (JGR-E), Geochemistry, Geophysics, Geosystems (G3), and Geophysical Research Letters (GRL). 1. Droughts threaten Bornean rainforests At 130 million years old, the rainforests of Southeast Asia are the oldest in the world and home to thousands of plant and animal species, some endemic to these forests. The rainforests ...

AAAS joins more than 3000 organizations in urging Congress to avoid 'devastating' budget cuts

2012-07-17
The American Association for the Advancement of Science (AAAS) has joined more than 3000 national, state, and local organizations in warning the U.S. Congress and President Barack Obama that automatic budget cuts set for January could have "devastating" effects on research, education, social services, security, and international relations. The planned cuts threaten federal programs that "support economic growth and strengthen the safety and security of every American in every state and community across the nation," the groups wrote in a 12 July letter to Congress. "We ...

Toughened silicon sponges may make tenacious batteries

2012-07-17
HOUSTON – (July 16, 2012) – Researchers at Rice University and Lockheed Martin reported this month that they've found a way to make multiple high-performance anodes from a single silicon wafer. The process uses simple silicon to replace graphite as an element in rechargeable lithium-ion batteries, laying the groundwork for longer-lasting, more powerful batteries for such applications as commercial electronics and electric vehicles. The work led by Sibani Lisa Biswal, an assistant professor of chemical and biomolecular engineering at Rice, and lead author Madhuri Thakur, ...

Poor people value marriage as much as the middle class and rich, study shows

2012-07-17
Poor people hold more traditional values toward marriage and divorce than people with moderate and higher incomes, UCLA psychologists report in the current issue of the Journal of Marriage and Family. The findings are based on a large survey about marriage, relationships and values, analyzed across income groups. They raise questions about how effectively some $1billion in government spending to promote the value of marriage among the poor is being spent. "A lot of government policy is based on the assumption that low-income people hold less traditional views about ...

New York Stem Cell Foundation scientists featured for new model of Alzheimer's disease

2012-07-17
NEW YORK, NY (July 16, 2012) – A team of scientists at The New York Stem Cell Foundation (NYSCF) Laboratory led by Scott Noggle, PhD, NYSCF–Charles Evans Senior Research Fellow for Alzheimer's Disease, has developed the first cell-based model of Alzheimer's disease (AD) by reprogramming skin cells of Alzheimer's patients to become brain cells that are affected in Alzheimer's. This will allow researchers to work directly on living brain cells suffering from Alzheimer's, which until now had not been possible. Andrew Sproul, PhD, a postdoctoral associate in Dr. Noggle's laboratory, ...

Physicians don't adequately monitor patients' medication adherence

2012-07-17
Patients' non-adherence to prescribed medication costs the U.S. health care system an estimated $290 billion annually and can lead to poor clinical outcomes, increased hospitalizations and higher mortality. In an effort to understand the extent to which health care providers feel responsible for their patients' medication adherence, UCLA researchers and colleagues conducted focus-group discussions with providers and recorded out-patient office visits with 100 patients taking a total of 410 medications. They also examined how adherence discussions were initiated between ...

NASA satellite sees strengthening in Tropical Cyclone Khanun

2012-07-17
When NASA's Aqua satellite passed over Tropical Depression Khanun on July 15, infrared data revealed some high, strong thunderstorms that hinted the cyclone would intensify. On July 16 Khanun had indeed become a tropical storm. NASA's Aqua satellite flew over Khanun on July 15, 2012 at 1635 UTC (12:35 p.m. EDT) when it was a tropical depression. At that time the Atmospheric Infrared Sounder (AIRS) instrument onboard measured Khanun's cloud top temperatures. The storm's coldest cloud top temperatures were as cold as or colder than -63 Fahrenheit (-52 Celsius), indicating ...

Satellite sees Hurricane Fabio still chasing Emilia's remnants in Pacific Ocean

2012-07-17
Hurricane Fabio continues to be the big tropical news maker in the Eastern Pacific, while the Central Pacific Hurricane Center is tracking the remnants of Hurricane Emilia. Both storms were captured on one satellite image from NOAA's GOES-15 satellite on July 16. Emilia's remnants appear as a light swirl of clouds on satellite imagery from NOAA's GOES-15 satellite. GOES-15 sits in a fixed orbit over the western U.S. and provides weather imagery. In an image from July 16 at 1500 UTC (11 a.m. EDT) while Hawaii was still in the pre-dawn hours, infrared imagery on GOES-15 ...

UC research reveals largest ancient dam built by Maya in Central America

2012-07-17
Recent excavations, sediment coring and mapping by a multi-university team led by the University of Cincinnati at the pre-Columbian city of Tikal, a paramount urban center of the ancient Maya, have identified new landscaping and engineering feats, including the largest ancient dam built by the Maya of Central America. That dam – constructed from cut stone, rubble and earth – stretched more than 260 feet in length, stood about 33 feet high and held about 20 million gallons of water in a man-made reservoir. These findings on ancient Maya water and land-use systems at ...

Are consumers aware that they are drawn to the center when choosing products?

2012-07-17
Consumers are more likely to select products located in the horizontal center of a display and may not make the best choices as a result, according to a new study in the Journal of Consumer Research. "A close investigation of visual attention reveals that consumers do not accurately recall their choice process. Our findings emphasize the relationship between horizontal location, attention, and choice," write authors A. Selin Atalay (HEC Paris), H. Onur Bodur (Concordia University), and Dina Rasolofoarison (Aston Business School). Many products are arranged horizontally. ...

Study examines autism law, financial burdens

2012-07-17
While the causes of autism continue to be debated and bandied about, real families who have children with autism spectrum disorders are left to struggle with expensive health care needs. These costs can be devastating - but they can also be markedly different if the family lives in Massachusetts or Maine. Advocates in many states have lobbied for legislation to force private insurers to offer autism services at the same levels as other covered services. A new study by Susan Parish, the Nancy Lurie Marks Professor of Disability Policy at the Heller School for Social Policy ...

Sharing isn't always caring: Why don't consumers take care of their Zipcars?

2012-07-17
Consumers who access products in the short-term instead of owning them show greater indifference toward these products and identify less with the brand and other consumers, according to a new study in the Journal of Consumer Research. "Our study represents the first look at how consumers think, feel, and act when they are accessing rather than purchasing products, and we discovered that the nature of access-based consumption is inherently different from ownership," write authors Fleura Bardhi (Northeastern University) and Giana M. Eckhardt (Suffolk University). The ...

Sodium buildup in brain linked to disability in multiple sclerosis

2012-07-17
OAK BROOK, Ill. – A buildup of sodium in the brain detected by magnetic resonance imaging (MRI) may be a biomarker for the degeneration of nerve cells that occurs in patients with multiple sclerosis (MS), according to a new study published online in the journal Radiology. The study found that patients with early-stage MS showed sodium accumulation in specific brain regions, while patients with more advanced disease showed sodium accumulation throughout the whole brain. Sodium buildup in motor areas of the brain correlated directly to the degree of disability seen in ...

Calculations reveal fine line for hydrogen release from storage materials

2012-07-17
Hydrogen, the simplest and most abundant element on Earth, is a promising energy carrier for emerging clean energy technology. Hydrogen is the energy carrier that powers fuel cells in electric cars, and can be used to store energy generated by renewable sources at times of low demand. A major challenge with hydrogen energy is meeting the dual goals of high storage density and efficient kinetics for hydrogen release when it is needed. Scientists at the University of California, Santa Barbara, have shed new light on the kinetics of hydrogen release, or dehydrogenation, ...
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