When the "fire brigade" arrives too late Impaired protein degradation causes muscle diseases RUB researchers and international colleagues report in Brain New insights into certain muscle diseases, the filaminopathies, are reported by an international research team led by Dr. Rudolf Andre Kley of the RUB's University Hospital Bergmannsheil in the journal Brain. The scientists from the Neuromuscular Centre Ruhrgebiet (headed by Prof. Matthias Vorgerd) at the Neurological University Clinic (Director: Prof. Martin Tegenthoff) cooperated with colleagues from eleven institutes ...

Improved home care resources for people with conditions such as dementia, who would prefer to die at home, are key to providing better end of life care and reducing the strain of the UK's ageing population on the NHS, according to researchers at King's College London. A new study, carried out by researchers from the Cicely Saunders Institute at King's and funded by the National Institute for Health Research Health Services &Delivery Research (NIHR HS&DR) Programme, found that 42 per cent of patients with advanced non-malignant conditions reported a preference for home ...

LOS ANGELES (Sept. 25, 2012) – Chronic, debilitating pain and potential organ failure are what approximately 100,000 sickle cell patients in the United States live with each day. Yutaka Niihara, M.D., M.P.H. - lead investigator at The Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) and co-founder of Emmaus Medical, Inc., an LA BioMed spin-off company - is developing a low-cost, noninvasive treatment that helps provide relief for patients suffering from the debilitating effects of sickle cell disease. Dr. Niihara and his team of investigators ...

Researchers from North Carolina State University have developed a new technique to identify the proteins secreted by a cell. The new approach should help researchers collect precise data on cell biology, which is critical in fields ranging from zoology to cancer research. The work is important because cells communicate by secreting proteins. Some of the proteins act on the cell itself, telling it to grow or multiply, for example. But the proteins can also interact with other cells, influencing them to perform any biological function. Traditionally, scientists who wanted ...

CAMBRIDGE, Mass. -- If you throw a ball underwater, you'll find that the smaller it is, the faster it moves: A larger cross-section greatly increases the water's resistance. Now, a team of MIT researchers has figured out a way to use this basic principle, on a microscopic scale, to carry out biomedical tests that could eventually lead to fast, compact and versatile medical-testing devices. The results, based on work by graduate student Elizabeth Rapoport and assistant professor Geoffrey Beach, of MIT's Department of Materials Science and Engineering (DMSE), are described ...

WASHINGTON, Sept. 25, 2012 — A new episode in the American Chemical Society's (ACS') popular Prized Science video series features insights into the effects of wind-blown dust on human health and climate from Vicki Grassian, Ph.D. She has jokingly been called "the Dust Queen" and is a noted authority on the tiny particles of sand and dirt, termed mineral dust, that are transported from areas as remote as the Sahara Desert. The video, produced by the ACS, the world's largest scientific society, is available at www.acs.org/PrizedScience and by request on DVD. Prized Science ...

MANHATTAN, KAN. -- A Kansas State University professor's research improving post-surgery pain treatment and osteoarthritis therapy in dogs may help develop better ways to treat humans for various medical conditions. From the use of hot and cold packs to new forms of narcotics, James Roush, professor of clinical sciences, is studying ways to lessen pain after surgery and improve care for small animals, particularly dogs. He is working with the clinical patients who come to the College of Veterinary Medicine's Veterinary Health Center. Because humans and dogs experience ...

WACO, Texas (Sept. 25, 2012) — Moving through the traditional stages of grief can be as unpredictable as playing a pinball machine, with triggers of sorrow acting like pinball rudders to send a mourner into a rebound rather than an exit, according to a case study by a Baylor University researcher and a San Antonio psychologist. For some, grieving is complete after the loss is accepted. But for others, such events as the anniversary of a death or a scene that jogs the memory can send them slamming into grief again, according to a case study by Margaret Baier, Ph.D., an ...

Are the longevity and vitality of traditional Chinese medicine (TCM) due to its holistic approach? Indeed, Chinese medicine is not simply about treating illness, but rather about taking care of the whole person—body, mind, and spirit. According to an analysis¹ of TCM's origins and development by Lin Shi from Beijing Normal University and Chenguang Zhang from Southwest Minzu University in China, traditional Chinese medicine is profoundly influenced by Chinese philosophy and religion. To date, modern science has been unable to explain the mechanisms behind TCM's effects. ...

Los Angeles (September 25, 2012)- With ties to diabetes, hypertension, and high cholesterol, childhood obesity in wealthy countries is certainly of growing concern to researchers. A new study explores the ties between childhood weight problems, socioeconomic status, and nationality and finds that race, ethnicity, and immigrant status are risk factors for weight problems among children in the US and England. This new study was published in the September issue of The ANNALS of the American Academy of Political and Social Science (a SAGE journal) titled "Migrant Youths and ...

How can laptop users be kinder to the environment by using less power? University of Cincinnati computer science doctoral student Dippy Aggarwal will be among the leaders in their fields who are sharing emerging research and career interests at the Grace Hopper Celebration of Women in Computing Conference, Oct. 3-6, in Baltimore. She'll present early results of her research in a poster presentation, "Leveraging Power Analytics and Linked Data for Enterprise Computing," on Wednesday, Oct. 3. Aggarwal's presentation evolved from a summer 2011 internship at the Digital ...

WASHINGTON—Research comparing brain development in humans and our closest nonhuman primate relatives, chimpanzees, reveals how quickly myelin in the cerebral cortex grows, shedding light on the evolution of human cognitive development and the vulnerability of humans to psychiatric disorders, a GW professor finds. Myelin is the fatty insulation surrounding axon connections of the brain. Recent research by Chet Sherwood, associate professor of anthropology in Columbian College of Arts and Sciences, along with Daniel Miller, a former GW graduate student, and other colleagues, ...

CHICAGO—In today's fast-paced society, consumers often reach for nutrition bars when looking for a healthy on-the-go snack. A new study in the September issue of the Journal of Food Science published by the Institute of Food Technologists (IFT) found that partially replacing canola oil with fish oil in nutrition bars can provide the health benefits of omega-3 fatty acids without affecting the taste. Producers have been hesitant to incorporate fish oil into foods because it tends to give off a fishy taste or smell, therefore requiring additional processing steps to eliminate ...

CHICAGO—A new study in the Journal of Food Science, published by the Institute of Food Technologists (IFT), shows that grape skin and seeds generated from winemaking—known as wine pomace—are a good source of antioxidant dietary fiber and can be used to fortify various food products such as yogurts and salad dressings with enhanced nutritional value and extended shelf-life. The researchers from Oregon State University analyzed pomace from Pinot Noir and Merlot wines to determine the most economically feasible ways to convert the rich source of antioxidants in pomace into ...

Although they're a common nuisance in the home, fruit flies have made great contributions to research in genetics and developmental biology. Now a Tel Aviv University researcher is again turning to this everyday pest to answer crucial questions about how neurons function at a cellular level — which may uncover the secrets of neurological disorders such as Alzheimer's disease. Approximately 75 percent of the genes that are related to diseases in humans are also to be found in the fly, says Ya'ara Saad, a PhD candidate in the lab of Prof. Amir Ayali at TAU's Department ...

Researchers in Georgia Tech's Center for Behavior Imaging have developed two new technological tools that automatically measure relevant behaviors of children, and promise to have significant impact on the understanding of behavioral disorders such as autism. One of the tools—a system that uses special gaze-tracking glasses and facial-analysis software to identify when a child makes eye contact with the glasses-wearer—was created by combining two existing technologies to develop a novel capability of automatic detection of eye contact. The other is a wearable system that ...

Washington, DC—U.S. health care spending grew at a faster pace than expected in 2011, according to a new report from the Health Care Cost Institute (HCCI). The Health Care Cost and Utilization Report: 2011 provides the first broad look at 2011 health care spending among those with employer-sponsored insurance (ESI). HCCI found that average dollars spent on health care services for that population climbed 4.6 percent in 2011, reaching $4,547 per person. This was well above the 3.8 percent growth rate observed in 2010 and beyond expected growth for 2011. Consumers ...

ITHACA, N.Y. — For more than 50 years, language scientists have assumed that sentence structure is fundamentally hierarchical, made up of small parts in turn made of smaller parts, like Russian nesting dolls. But a new Cornell University study suggests language use is simpler than they had thought. Co-author Morten Christiansen, Cornell professor of psychology and co-director of the Cornell Cognitive Science Program, and his colleagues say that language is actually based on simpler sequential structures, like clusters of beads on a string. "What we're suggesting is ...

RICHMOND, Va. (Sept. 25, 2012) – People who smoke both cigarettes and waterpipes – dual users – lack sufficient knowledge about the risks of tobacco smoking and are at considerable risk for dependence and tobacco-related diseases, such as cancer, heart disease and stroke later in life, according to findings of a new study by Virginia Commonwealth University. The study, the first of its kind to assess trends in cigarette and waterpipe tobacco smoke based on long-term data, reveals few users perceive dangers of waterpipe tobacco. A common misconception about waterpipe ...

New York, NY (September 25, 2012) — Researchers in the Taub Institute at Columbia University Medical Center (CUMC) have identified a mechanism that appears to underlie the common sporadic (non-familial) form of Parkinson's disease, the progressive movement disorder. The discovery highlights potential new therapeutic targets for Parkinson's and could lead to a blood test for the disease. The study, based mainly on analysis of human brain tissue, was published today in the online edition of Nature Communications'. Studies of rare, familial (heritable) forms of Parkinson's ...

A strong democracy depends on smart voters who choose their leaders based on their knowledge of important political issues. One of the ways that Americans learn about politics is by following the news. Now, researchers from the University of Missouri School of Journalism have found that simply following the news is not enough. A panel survey involving more than 1,200 teenagers from 12 to 17 years of age found that adolescents learn more about politics when they think and talk about what they read or watch on the news. Edson Tandoc, a doctoral student at MU, found that ...

September 25, 2012 A new video protocol in Journal of Visualized Experiments (JoVE) details an assay to identify brain tumor initiating stem cells from primary brain tumors. Through flow cytometry, scientists separate stem cells from the rest of the tumor, allowing quick and efficient analysis of target cells. This approach has been effectively used to identify similar stem cells in leukemia patients. "Overall, these tumors are extremely rare, with only around one in 100,000 people being diagnosed with a primary brain cancer," Dr. Sheila Singh, co-author and neurosurgeon ...

This press release is available in German. To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimetre in size, long sections of the DNA must be strongly compacted. Epigenetic marks maintain these sections, known as heterochromatin. Scientists of the Max Planck Institute of Immunobiology and Epigenetics in Freiburg have now discovered two further mechanisms necessary for the formation of heterochromatin. The research group, led by Thomas Jenuwein, describes two novel enzymes, Prdm3 and Prdm16, which attach a methyl group to ...

The financial effects of alcoholism on the family members of addicts can be massive, but little is known about whether treatment for alcoholism reduces that financial burden. A study of 48 German families published online today in the journal Addiction reveals that after twelve months of treatment, family costs directly related to a family member's alcoholism decreased from an average of €676.44 (£529.91, US$832.26) per month to an average of €145.40 (£113.90, $178.89) per month. Put another way, average costs attributable to alcoholism decreased from 20.2% to 4.3% of ...

PHILADELPHIA — A new research model has estimated that the difference in prostate cancer mortality among men with low-risk disease who choose active surveillance versus those who choose immediate treatment with radical prostatectomy is likely to be very modest, possibly as little as two to three months. The model, developed by biostatistician Ruth Etzioni, Ph.D., and colleagues of the Public Health Sciences Division at Fred Hutchinson Cancer Research Center in Seattle, Wash., is among the first to use specific data from published studies to project the likelihood of ...