The NBA league is more equal than the ACB
2012-08-13
Competitiveness amongst NBA teams is more constant throughout seasons than during the ACB basketball league (Spain), which also falls after every Olympic Games. According to a study from the University of Las Palmas de Gran Canaria, the differences could be attributed to economic and organisational reasons: in the NBA there is just one division, there is a salary cap and the weakest teams have access to good players.
The National Basketball Association (NBA) of North America and the Association of Basketball Clubs (ACB) of Spain are the best and most competitive basketball ...
Ancient seal may add substance to the legend of Samson
2012-08-13
Tel Aviv University researchers recently uncovered a seal, measuring 15 millimetres (about a half-inch) in diameter, which depicts a human figure next to a lion at the archaeological site of Beth Shemesh, located between the Biblical cities of Zorah and Eshtaol, where Samson was born, flourished, and finally buried, according to the book of Judges. The scene engraved on the seal, the time period, and the location of the discovery all point to a probable reference to the story of Samson, the legendary heroic figure whose adventures famously included a victory in hand-to-paw ...
AERA et al. bring science to bear in major affirmative action case
2012-08-13
WASHINGTON, August 13, 2012─On August 13, AERA filed an amicus curiae brief in the U.S. Supreme Court case of Fisher v. University of Texas at Austin. The association is joined by seven other scientific societies in urging the Court to consider an overwhelming body of scientific evidence relevant to the case. "AERA has a fundamental interest in the accurate presentation of social science research on these important questions of law. Quite simply, we have a responsibility to enable the Court to make its determinations based on the best scientific evidence available," ...
Human embryos frozen for 18 years yield viable stem cells suitable for biomedical research
2012-08-13
New Rochelle, NY, August 13, 2012—Even after being frozen for 18 years, human embryos can be thawed, grown in the laboratory, and successfully induced to produce human embryonic stem (ES) cells, which represent a valuable resource for drug screening and medical research. Prolonged embryonic cryopreservation as an alternative source of ES cells is the focus of an article in BioResearch Open Access, a new bimonthly peer-reviewed open access journal from Mary Ann Liebert, Inc. The article is available free online at the BioResearch Open Access website.
Kamthorn Pruksananonda ...
Rejected drug may protect against toxic substance common to Alzheimer's and Parkinson's diseases
2012-08-13
The second of two studies on latrepirdine, recently published in Molecular Psychiatry, demonstrates new potential for the compound in the treatment of Alzheimer's disease, Parkinson's disease, sleep disorders, and other neurodegenerative conditions. An international team led by Mount Sinai School of Medicine scientists found that latrepiridine, known commercially as Dimebon, reduced the level of at least two neurodegeneration-related proteins in mice.
Latrepirdine was initially sold as an antihistamine in Russia, following its approval for use there in 1983. In the 1990s, ...
Diabetes drugs taken by over 15 million Americans raises risk of bladder cancer
2012-08-13
PHILADELPHIA -- A popular class of diabetes drugs increases patients' risk of bladder cancer, according to a new study published online this month in the Journal of the National Cancer Institute. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that patients taking thiazolidinedione (TZDs) drugs – which account for up to 20 percent of the drugs prescribed to diabetics in the United States -- are two to three times more likely to develop bladder cancer than those who took a sulfonylurea drug, another common class of medications for ...
Mount Sinai researchers identify new drug target for schizophrenia
2012-08-13
Researchers at Mount Sinai School of Medicine may have discovered why certain drugs to treat schizophrenia are ineffective in some patients. Published online in Nature Neuroscience, the research will pave the way for a new class of drugs to help treat this devastating mental illness, which impacts one percent of the world's population, 30 percent of whom do not respond to currently available treatments.
A team of researchers at Mount Sinai School of Medicine set out to discover what epigenetic factors, or external factors that influence gene expression, are involved in ...
Existing drugs offer new treatment options for high-risk childhood leukemia subtype
2012-08-13
Scientists have identified new genetic alterations underlying a high-risk subtype of the most common childhood cancer that could be effectively targeted with existing leukemia therapies.
The study focused on a subtype of acute lymphoblastic leukemia (ALL) known as Philadelphia chromosome-like ALL (Ph-like ALL). This subgroup accounts for as much as 15 percent of childhood ALL that is associated with a high risk of relapse and a poor outcome. The genetic changes driving the disease were previously unknown for about half of all patients with Ph-like ALL. The work identified ...
Are methane hydrates dissolving?
2012-08-13
The average temperatures of the atmosphere are rising; the average temperatures of the oceans, too. Not only living organisms react sensititvely to these changes. The transitional zones between shallow shelf seas and the deep sea at continental slopes store a huge amount of methane hydrates in the sea bed. These specific, ice-like compounds only forms at low temperatures and under high pressure. When the water temperature directly above the sea bed rises, some of the methane hydrates could dissolve and release the previously bound methane. "This scenario incorporates two ...
Scientists use light to 'tag and track' genetic processes
2012-08-13
In a new study, UT Dallas researchers outline how they used fluorescent molecules to "tag" DNA and monitor a process called DNA looping, a natural biological mechanism involved in rearranging genetic material in some types of cells.
The UT Dallas "tag and track" method not only sheds light on how DNA loops form, but also might be adapted to screen drugs for effectiveness against certain viruses that shuffle genetic material, such as HIV.
Until now, scientists primarily had "snapshots" of the initial and final stages of DNA loop formation, with only limited information ...
Consumers perceive risk when 'price' means more than money
2012-08-13
When companies combine different pricing structures – such as asking for effort or information in combination with or instead of money – consumers perceive a greater risk in the decision to buy.
That's according to University of Cincinnati research to be presented at the Aug. 15-17 Behavioral Pricing Conference in Detroit, Mich., by doctoral marketing student John Dinsmore. His paper is titled "Mental Accounting, General Evaluability Theory and the Framing Losses Posed by Partitioned Monetary and Nonmonetary Prices."
According to Dinsmore, shoppers routinely arrive ...
Butter flavoring in microwave popcorn, thought safe for food industry workers, is respiratory hazard
2012-08-13
Philadelphia, PA, August 13, 2012 – The ingredient 2,3-pentanedione (PD), used to impart the flavor and aroma of butter in microwave popcorn, is a respiratory hazard that can also alter gene expression in the brain of rats. Manufacturers started using PD when another butter flavoring, diacetyl, was found to cause bronchiolitis obliterans, a life-threatening and nonreversible lung disease in workers who inhaled the substance. New research on PD with implications for "popcorn workers' lung" is published in The American Journal of Pathology and indicates that acute PD exposure ...
Optics and photonics research priorities, grand challenges presented in new report
2012-08-13
WASHINGTON — A new report from the National Research Council identifies research priorities and grand challenges to fill gaps in optics and photonics, a field that has the potential to advance the economy of the United States and provide visionary directions for future technology applications. The report recommends that the federal government develop a "National Photonics Initiative" to bring together academia, industry, and government to steer federal research and development funding and activities.
"Much is unknown when pursuing basic optical science and its transition ...
Researchers identify key culprit causing muscle atrophy
2012-08-13
Whether you're old, have been ill, or suffered an injury, you've watched gloomily as your muscles have atrophied. The deterioration of muscle—even slight or gradual—is about as common to the human condition as breathing.
Yet despite its everyday nature, scientists know little about what causes skeletal muscles to atrophy. They know proteins are responsible, but there are thousands of possible suspects, and parsing the key actors from the poseurs is tricky.
In a new paper, researchers from the University of Iowa report major progress. The team has identified a single ...
New key element discovered in pathogenesis of Burkitt lymphoma
2012-08-13
Burkitt lymphoma is a malignant, fast-growing tumor that originates from a subtype of white blood cells called B lymphocytes of the immune system and often affects internal organs and the central nervous system. Now Dr. Sandrine Sander and Professor Klaus Rajewsky of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch have identified a key element that transforms the immune cells into malignant lymphoma cells. They developed a mouse model that closely resembles Burkitt lymphoma in humans and that may help to test new treatment strategies (Cancer Cell)*.
Burkitt ...
Gene discovery could improve treatment for acute myeloid leukemia
2012-08-13
August 13, 2012 ─ (BRONX, NY) ─ Scientists at Albert Einstein College of Medicine of Yeshiva University have made a discovery involving mice and humans that could mean that people with acute myeloid leukemia (AML), a rare and usually fatal cancer, are a step closer to new treatment options. Their study results were published online today in Cancer Cell.
"We have discovered that a gene called HLX is expressed at abnormally high levels in leukemia stem cells in a mouse model of AML," said Ulrich Steidl, M.D., Ph.D., assistant professor of cell biology and of ...
Chromosomal translocations point the way toward personalized cancer care
2012-08-13
A broken chromosome is like an unmoored beansprout circling in search of attachment. If a cell tries to replicate itself with broken chromosomes, the cell will be killed and so it would very much like to find its lost end. Often, it finds a workable substitute: another nearby chromosome. When a broken chromosome attaches to another, or when chromosomes use a similar process to exchange genetic material, you've got a translocation – genes end up fused to other genes, encoding a new protein they shouldn't. A recent University of Colorado Cancer Center review in the journal ...
Why are people overconfident so often?
2012-08-13
UNIVERSITY OF CALIFORNIA, BERKELEY'S HAAS SCHOOL OF BUSINESS – Researchers have long known that people are very frequently overconfident – that they tend to believe they are more physically talented, socially adept, and skilled at their job than they actually are. For example, 94% of college professors think they do above average work (which is nearly impossible, statistically speaking). But this overconfidence can also have detrimental effects on their performance and decision-making. So why, in light of these negative consequences, is overconfidence still so pervasive?
The ...
Protective bacteria in the infant gut have resourceful way of helping babies break down breast milk
2012-08-13
A research team at the University of California, Davis, has found that important and resourceful bacteria in the baby microbiome can ferret out nourishment from a previously unknown source, possibly helping at-risk infants break down components of breast milk.
Breast milk is amazingly intricate, providing all of the nutrients necessary to sustain and strengthen infants in the first months of life. Moreover, this natural source of nutrition provides protection from infections, allergies and many other illnesses.
Breast milk also promotes the growth of protective bacteria ...
Wind farms: A danger to ultra-light aircraft?
2012-08-13
For a motorized hangglider or a one-seater weighing 300 kilograms: the business of flying by ultra-light aircraft is booming. That is also why numerous airfields are applying for the license to host these lightweight gliders. Most of these airfields are located on flat land, which is also the preferred terrain for wind power plant. However, these facilities could turn out to be a risk factor for aviators, especially when it comes to takeoff and landing: On the one hand, the power plants "pilfer" the winds from the planes, because wind speeds aft of such facilities are considerably ...
New oncogene identified for breast cancer
2012-08-13
A team of researchers at Case Western Reserve University School of Medicine, led by Dr. Mark W. Jackson, have developed a novel method to identify genes that, when overexpressed, make normal cells behave like cancer cells. Using this method, the Jackson laboratory has identified a new oncogene, which is a gene that contributes to the development of cancer, named FAM83B.
"We made our discovery in a model of breast cancer," said Mark W. Jackson, Ph.D., Assistant Professor, Department of Pathology, Case Western Reserve University School of Medicine, Case Comprehensive Cancer ...
Poor oral health can mean missed school, lower grades
2012-08-13
Poor oral health, dental disease, and tooth pain can put kids at a serious disadvantage in school, according to a new Ostrow School of Dentistry of USC study.
"The Impact of Oral Health on the Academic Performance of Disadvantaged Children," appearing in the September 2012 issue of the American Journal of Public Health, examined nearly 1500 socioeconomically disadvantaged elementary and high school children in the Los Angeles Unified School District, matching their oral health status to their academic achievement and attendance records.
Ostrow researchers had previously ...
For young adults, appearance matters more than health, MU research suggests
2012-08-13
VIDEO:
MU researchers studied how college-age women view their bodies and how they feel about media messages aimed at women. Based on focus group research findings, the MU team developed an...
Click here for more information.
COLUMBIA, Mo. –When it comes to college-age individuals taking care of their bodies, appearance is more important than health, research conducted at the University of Missouri suggests. María Len-Ríos, an associate professor of strategic communication, ...
10 new diabetes gene links offer picture of biology underlying disease
2012-08-13
Ten more DNA regions linked to type 2 diabetes have been discovered by an international team of researchers, bringing the total to over 60.
The study provides a fuller picture of the genetics and biological processes underlying type 2 diabetes, with some clear patterns emerging.
The international team, led by researchers from the University of Oxford, the Broad Institute of Harvard and MIT, and the University of Michigan, Ann Arbor, used a new DNA chip to probe deeper into the genetic variations that commonly occur in our DNA and which may have some connection to type ...
Yale team discovers how stress and depression can shrink the brain
2012-08-13
Major depression or chronic stress can cause the loss of brain volume, a condition that contributes to both emotional and cognitive impairment. Now a team of researchers led by Yale scientists has discovered one reason why this occurs — a single genetic switch that triggers loss of brain connections in humans and depression in animal models.
The findings, reported in the Aug. 12 issue of the journal Nature Medicine, show that the genetic switch known as a transcription factor represses the expression of several genes that are necessary for the formation of synaptic connections ...
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