Researchers from Mount Sinai School of Medicine have for the first time used several imaging techniques to prove the efficacy of a promising new treatment for atherosclerosis—the build-up of plaque in artery walls that can lead to a heart attack. Using positron-emission tomography (PET)/computed tomography (CT) and magnetic resonance imaging (MRI), the research team showed that dalcetrapib, a novel treatment for atherosclerosis, prevented the progression of disease and reduced vascular inflammation over 24 months. The data are published in the September 12 issue of The ...

EVANSTON, Ill. --- A new Northwestern University study provides compelling evidence that human males are biologically wired to care for their offspring, conclusively showing for the first time that fatherhood lowers a man's testosterone levels. The effect is consistent with what is observed in many other species in which males help take care of dependent offspring. Testosterone boosts behaviors and other traits that help a male compete for a mate. After they succeed and become fathers, "mating-related" activities may conflict with the responsibilities of fatherhood, ...

CHICAGO – Among patients who have had an ischemic stroke, use of cholesterol-lowering statin medications is not associated with subsequent intracerebral hemorrhage (bleeding in the brain), according to a report published Online First by Archives of Neurology, one of the JAMA/Archives journals. According to background information in the article, after stroke or transient ischemic attack, patients are at increased risk for recurrent events. Results from the Stroke Prevention by Aggressive Lowering of Cholesterol Levels (SPARCL) trial and the Heart Protection Study (HPS) ...

CHICAGO – Intranasal insulin therapy appears to provide some benefit for cognitive function in patients with amnestic mild cognitive impairment and Alzheimer disease, according to a report published Online First today by Archives of Neurology, one of the JAMA/Archives journals. According to background information in the article, insulin plays a role in a number of functions of the central nervous system. "The importance of insulin in normal brain function is underscored by evidence that insulin dysregulation contributes to the pathophysiology of Alzheimer disease (AD), ...

CHICAGO – Many U.S. adults believe that only extremely effective drugs without serious adverse effects are approved, but providing explanations to patients highlighting uncertainties about drug benefits may affect their choices, according to a report in the September issue of Archives of Internal Medicine, one of the JAMA/Archives journals. The article is part of the journal's Less Is More series. Approval from the U.S. Food and Drug Administration (FDA) does not necessarily ensure that a drug has a large or important benefit, or that all serious adverse effects of the ...

CHICAGO – Long-term use of nonaspirin anti-inflammatory drugs (NSAIDs) is associated with an increased risk of renal cell cancer (RCC), according to a report in the September issue of Archives of Internal Medicine, one of the JAMA/Archives journals. According to background information in the article, in the United States, kidney cancer is the seventh leading type of cancer among men and the ninth leading type of cancer among women. The most common type of kidney cancer, renal cell cancer, accounts for 85 percent of all cases. Analgesics (pain-relieving medications) are ...

CHICAGO – An association has been found between infection associated with cardiovascular implantable electronic devices (CIEDs) and increases in mortality and hospital care costs, according to a report published Online First by Archives of Internal Medicine, one of the JAMA/Archives journals. The article is part of the journal's Health Care Reform series. Therapy with CIEDs, which include pacemakers, implantable cardioverter-defibrillators and cardiac resynchronization therapy/defibrillator devices, can reduce illness and death rates in appropriately selected patients, ...

Skin Solutions Medical Spa has been serving the Denver Metro area for the past 15 years and was recently nominated for Denver 7's A-List as Denver's best Medical Spa. The spa stands out in the community by providing the highest level of customer service while producing state-of-the-art cosmetic procedures and aesthetic treatments that are safe and effective. The announcement of Express Rejuvenation Day shows the spa's commitment to provide even more quality to their clients and community. Skin Solutions Medical Spa's new Express Rejuvenation Day was driven by the demand ...

A new set of harmonized guidelines for the management of risk factors for cardiovascular disease will make it much easier for physicians to care for their patients, according to the authors of the C-CHANGE guidelines published in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/site/embargo/cmaj101508.pdf. The Canadian Cardiovascular Harmonized National Guideline Endeavour (C-CHANGE) Initiative harmonized and integrated more than 400 separate recommendations from 8 sets of guidelines into one comprehensive but simplified resource. ...

Young children who watch fast-paced, fantastical television shows may become handicapped in their readiness for learning, according to a new University of Virginia study published in the October issue of the journal Pediatrics. U.Va. psychologists tested 4-year-old children immediately after they had watched nine minutes of the popular show "SpongeBob SquarePants" and found that their executive function – the ability to pay attention, solve problems and moderate behavior – had been severely compromised when compared to 4-year-olds who had either watched nine minutes of ...

Monmouth Junction, NJ (September 12, 2011): A new study finds that infections following cardiac device implantations or replacement result in extremely high costs, both financially and in terms of patient mortality, even months after affected patients return home. Infections associated with pacemakers and defibrillators led to 4.8 to 7.7-fold increases in admission mortality, 1.6 to 2.1-fold increases long term mortality, 2.5 to 4.0-fold increases in hospital length of stay, and 1.4 to 1.8-fold increases in cost compared to pacemaker and defibrillator implantations without ...

According to a study published this week in the September/October 2011 issue of the American Journal of Health Promotion (Vol. 26, No. 1, pp. 56-60), people with consistently high health care costs experienced a 28 percent cumulative decrease in physician fees after an average of five years practicing the stress-reducing Transcendental Meditation technique compared with their baseline. Both between and within group comparisons were statistically significant. This study has major policy implications. In most populations, a small fraction of people account for the majority ...

CAMBRIDGE, Mass. -- An airplane's digital flight-data recorder, or "black box," holds massive amounts of data, documenting the performance of engines, cockpit controls, hydraulic equipment and GPS systems, typically at regular one-second intervals throughout a flight. Inspectors use such data to reconstruct the final moments of an accident, looking for telltale defects that may explain a crash. More recently, analysts have probed black-box data in an effort to prevent such accidents from ever occurring. Using software tools that can rapidly search data, operators can ...

Among the many ways that participation in Alcoholics Anonymous (AA) helps its members stay sober, two appear to be most important – spending more time with individuals who support efforts towards sobriety and increased confidence in the ability to maintain abstinence in social situations. In a paper that will appear in the journal Addiction and has been released online, researchers report the first study to examine the relative importance to successful recovery of the behavior changes associated with participation in AA. "AA is the most commonly sought source of help ...

CHICAGO – Lifestyle modifications and pharmaceutical treatment of risk factors for cardiovascular disease are associated with improvement in sexual function among men with erectile dysfunction (ED), according to a meta-analysis posted Online First today in Archives of Internal Medicine, one of the JAMA/Archives journals. "Erectile dysfunction shares modifiable risks factors with atherosclerosis and coronary artery disease (CAD), including hypertension, diabetes, dyslipidemia, cigarette smoking, obesity, metabolic syndrome, and sedentary behavior," according to background ...

This press release is available in Spanish. A commercial enzyme could reduce overall costs linked with producing ethanol from grain, and also reduce associated emissions of greenhouse gases, according to a study by U.S. Department of Agriculture (USDA) scientists and colleagues. The researchers found that the enzyme helps extract water from an ethanol byproduct used to make dried distillers grains with solubles (DDGS), which can be used as feed supplements for cattle, swine and poultry. This could significantly reduce the amount of electricity, natural gas, energy and ...

CHICAGO – Repeated exposure of the eye to ophthalmic antibiotics appears to be associated with the emergence of resistant strains of microbes among patients undergoing intraocular injection therapy for neovascular retinal disease, according to a report in the September issue of Archives of Ophthalmology, one of the JAMA/Archives journals. According to background information in the article, more than 8 million people in the United States are affected by age-related macular degeneration, the leading cause of blindness among individuals older than 65 years in this country. ...

Berkeley – Engineers at the University of California, Berkeley, have shown that it is possible to reduce the minimum voltage necessary to store charge in a capacitor, an achievement that could reduce the power draw and heat generation of today's electronics. "Just like a Formula One car, the faster you run your computer, the hotter it gets. So the key to having a fast microprocessor is to make its building block, the transistor, more energy efficient," said Asif Khan, UC Berkeley graduate student in electrical engineering and computer sciences. "Unfortunately, a transistor's ...

Quebec City, September 12, 2011—A study presented today by Université Laval researchers at the 4th World Congress on Sleep Medicine currently underway in Quebec City revealed that the risk of insomnia is 67% higher in people from families in which at least one member is an insomniac. The research team, directed by Dr. Charles M. Morin of Université Laval's School of Psychology, came to these conclusions following a study involving 3,485 people. The participants were asked to answer a telephone survey on their sleep quality and that of their immediate families. On three ...

Heart attack patients with psoriasis are 26 per cent more likely to die from cardiovascular disease, or suffer from recurrent heart attacks or strokes, and are 18 per cent more likely to die from all causes than those without the inflammatory skin disease. That's the key finding of a Danish study published in the September issue of the Journal of Internal Medicine. Researchers studied nearly 50,000 patients who had experienced their first heart attack between 2002 and 2006, following the 462 patients with psoriasis for an average of 19.5 months and the 48,935 controls ...

Bochum's physicists led by Prof. Dr. Hartmut Zabel have demonstrated the spin pumping effect in magnetic layers for the first time experimentally. The behaviour of the spin pumping had previously only been predicted theoretically. The research team at the RUB has now succeeded in measuring the effect using ultrafast X-ray scattering with picosecond resolution. Through their rotation of the magnetic moments, the so-called magnetic precession, single electrons can mutually influence each other's rotation (spin) through a non-magnetic intermediate layer. This is a crucial ...

Jerusalem, Sept. 11, 2011 -- Researchers at the Hebrew University of Jerusalem have identified the key signal that prompts production of insulin-producing beta cells in the pancreas -- a breakthrough discovery that may ultimately help researchers find ways to restore or increase beta cell function in people with type 1 diabetes. The work on the multi-year project was led by Prof. Yuval Dor of the Institute for Medical Research Israel-Canada of the Hebrew University, researchers from the Hadassah University Medical Center and researchers from the diabetes section of the ...

Choosing the sex of our offspring may seem totally beyond our control, but some animals have a remarkable capacity to manipulate this. The female eclectus parrot, for example, has been known to produce 20 sons in a row before switching to producing only daughters. Now, a team of evolutionary biologists has found that tight control over offspring sex ratios can have disastrous consequences for sexual selection. Led by Dr Tim Fawcett, a research fellow at the University of Bristol, the team used mathematical models and computer simulations to investigate how sex-ratio ...

A common chemotherapy drug has been successfully delivered to cancer cells inside tiny microparticles using a method inspired by our knowledge of how the human immune system works. The drug, delivered in this way, reduced ovarian cancer tumours in an animal model by 65 times more than using the standard method. This approach is now being developed for clinical use. The research was funded by, among others, the Biotechnology and Biological Sciences Research Council (BBSRC) Follow-on Fund - funding for 'proof of concept' at the very early stage of turning research outputs ...

This press release is available in French. Toxin proteins are genetically engineered into our food because they kill insects by perforating body cell walls, and Professor Rikard Blunck of the University of Montreal's Group for the study of membrane proteins (GÉPROM) has detected the molecular mechanism involved. In recognition of his breakthrough, he received the Traditional Paul F. Cranefield Award of the Society of General Physiologists yesterday evening. "This study is about gaining a better understanding of the basic functioning of the toxin proteins in order to judge ...