Olympia hypothesis: Tsunamis buried the cult site on the Peloponnese
2011-07-12
Olympia, site of the famous Temple of Zeus and original venue of the Olympic Games in ancient Greece, was presumably destroyed by repeated tsunamis that travelled considerable distances inland, and not by earthquake and river floods as has been assumed to date. Evidence in support of this new theory on the virtual disappearance of the ancient cult site on the Peloponnesian peninsula comes from Professor Dr Andreas Vött of the Institute of Geography of Johannes Gutenberg University Mainz, Germany. Vött investigated the site as part of a project in which he and his team are ...
Ant colonies: Behavioral variability wins
2011-07-12
They attack other colonies, plunder and rob, kill other colonies' inhabitants or keep them as slaves: Ants are usually regarded as prototypes of social beings that are prepared to sacrifice their lives for their community, but they can also display extremely aggressive behavior towards other nests. The evolution and behavior of ants, in particular the relationship between socially parasitic ants and their hosts, is the research topic of a work group headed by Professor Dr Susanne Foitzik at the Institute of Zoology at Johannes Gutenberg University Mainz, Germany. Evolutionary ...
Poor bone health may start early in people with multiple sclerosis
2011-07-12
ST. PAUL, Minn. – Osteoporosis and low bone density are common in people in the early stages of multiple sclerosis (MS), according to a new study published in the July 12, 2011, print issue of Neurology®, the medical journal of the American Academy of Neurology.
"We've known that people who have had MS for a long time are at a greater risk of low bone density and broken bones, but we didn't know whether this was happening soon after the onset of MS and if it was caused by factors such as their lack of exercise due to lack of mobility, or their medications or reduced ...
No difference in brand name and generic drugs regarding thyroid dysfunction
2011-07-12
There is no difference between brand-name and generic drug formulations of amiodarone — taken to control arrhythmia – in the incidence of thyroid dysfunction, according to a study in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/site/embargo/cmaj101800.pdf.
Amiodarone, prescribed to control irregular heartbeats, is known for causing hypo- and hyper-thyroidism. Amiodarone is available in Canada in brand-name formulations as well as less costly generic versions. Generic formulations may be substituted if considered bioequivalent ...
Alcohol consumption guidelines inadequate for cancer prevention
2011-07-12
Current alcohol consumption guidelines are inadequate for the prevention of cancer and new international guidelines are needed, states an analysis in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/site/embargo/cmaj110363.pdf.
Guidelines in some countries are not currently based on evidence for long-term harm. Most guidelines are based on studies that assessed the short-term effects of alcohol, such as social and psychological issues and hospital admissions, and were not designed to prevent chronic diseases. As well, in some countries, ...
July/August 2011 Annals of Family Medicine tip sheet
2011-07-12
Power and Potential of Mobile Sensing Devices to Improve Health Care
Researchers from Dartmouth offer a provocative glimpse into the possibilities of wireless mobile technology to measure elderly patients' physical activity and social interactions and improve detection of changes in their health. Sensors on a waist-mounted wireless mobile device worn by eight patients aged 65 and older continuously measured patients' time spent walking level, up or down an elevation, and stationary (sitting or standing), and time spent speaking with one or more other people. Researchers ...
Bladder cancer patients rarely receive recommended care
2011-07-12
A new study has found that almost all patients with high-grade noninvasive bladder cancer do not receive complete care as recommended by current guidelines. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study indicates that efforts are needed to identify and overcome barriers to providing optimal care to patients with bladder cancer.
High-grade noninvasive bladder cancer has up to a 70 percent chance of recurring after treatment and up to a 50 percent chance of progressing to a more invasive tumor. Effective treatment for ...
Genetic switch for limbs and digits found in ancient fish
2011-07-12
Genetic instructions for developing limbs and digits were present in primitive fish millions of years before their descendants first crawled on to land, researchers have discovered.
Genetic switches control the timing and location of gene activity. When a particular switch taken from fish DNA is placed into mouse embryos, the segment can activate genes in the developing limb region of embryos, University of Chicago researchers report in Proceedings of the National Academy of Sciences. The successful swap suggests that the recipe for limb development is conserved in species ...
A classic instinct -- salt appetite -- is linked to drug addiction
2011-07-12
Durham, N.C., U.S. and Melbourne, Australia -- A team of Duke University Medical Center and Australian scientists has found that addictive drugs may have hijacked the same nerve cells and connections in the brain that serve a powerful, ancient instinct: the appetite for salt.
Their rodent research shows how certain genes are regulated in a part of the brain that controls the equilibrium of salt, water, energy, reproduction and other rhythms – the hypothalamus. The scientists found that the gene patterns activated by stimulating an instinctive behavior, salt appetite, ...
Landscape change leads to increased insecticide use in the Midwest
2011-07-12
MADISON - The continued growth of cropland and loss of natural habitat have increasingly simplified agricultural landscapes in the Midwest. A Great Lakes Bioenergy Research Center (GLBRC) study concluded that this simplification is associated with increased crop pest abundance and insecticide use, consequences that could be tempered by perennial bioenergy crops.
While the relationship between landscape simplification, crop pest pressure, and insecticide use has been suggested before, it has not been well supported by empirical evidence. This study, published online in ...
Regional system to cool cardiac arrest patients improves outcomes
2011-07-12
A broad, regional system to lower the temperature of resuscitated cardiac arrest patients at a centrally-located hospital improved outcomes, according to a study in Circulation: Journal of the American Heart Association.
Cooling treatment, or therapeutic hypothermia, is effective yet underused, researchers said.
A network of first responders, EMS departments and more than 30 independent hospitals within 200 miles of Minneapolis, Minn., and Abbott Northwestern Hospital collaborated to implement the protocol.
"We've shown that a fully integrated system of care, from ...
Obstructive sleep apnea linked to blood vessel abnormalities
2011-07-12
Obstructive sleep apnea may cause changes in blood vessel function that reduces blood supply to the heart in people who are otherwise healthy, according to new research reported in Hypertension: Journal of the American Heart Association.
However, treatment with 26 weeks of continuous positive airway pressure (CPAP) improved study participants' blood supply and function.
Obstructive sleep apnea, which causes periodic pauses in breathing during sleep, affects about 15 million adults in the United States, according to the American Heart Association. The sleep disorder ...
Nearly all patients with high-grade bladder cancer do not receive guideline-recommended care
2011-07-12
A study at UCLA's Jonsson Comprehensive Cancer Center found that nearly all patients with high-grade, non-invasive bladder cancer are not receiving the guideline-recommended care that would best protect them from recurrence, a finding that researchers characterized as alarming.
In fact, out of the 4,545 bladder cancer patients included in the study, only one received the comprehensive care recommended by the American Urology Association and the National Comprehensive Cancer Network.
Receiving the recommended comprehensive care for high-grade bladder cancer is critical ...
Do-it-yourself brain repair following stroke
2011-07-12
Stroke is a leading cause of long-term disability and death in the United States. A team of researchers — led by Gregory Bix, at Texas A&M College of Medicine, College Station — has identified a way to exploit one of the brain's self-repair mechanisms to protect nerve cells and enhance brain repair in rodent models of stroke. The authors suggest that this approach could provide a nontoxic treatment for stroke.
The most common form of stroke (ischemic stroke) occurs when a blood vessel that brings oxygen and nutrients to the brain becomes clogged, for example with a blood ...
PXR: A stepping stone from environmental chemical to cancer?
2011-07-12
Several chemicals that can accumulate to high levels in our body (for example BPA and some pesticides) have been recently linked to an increased risk of cancer and/or impaired responsiveness to anticancer drugs. A team of researchers, led by Sridhar Mani, at Albert Einstein College of Medicine, New York, has now identified a potential mechanistic link between environmental exposure to these foreign chemicals (xenogens) and cancer drug therapy response and survival.
PXR is one protein by which cells (including tumor cells) can sense xenogens. In their study, Mani and colleagues ...
JCI online early table of contents: July 11, 2011
2011-07-12
EDITOR'S PICK: Do-it-yourself brain repair following stroke
Stroke is a leading cause of long-term disability and death in the United States. A team of researchers — led by Gregory Bix, at Texas A&M College of Medicine, College Station — has identified a way to exploit one of the brain's self-repair mechanisms to protect nerve cells and enhance brain repair in rodent models of stroke. The authors suggest that this approach could provide a nontoxic treatment for stroke.
The most common form of stroke (ischemic stroke) occurs when a blood vessel that brings oxygen and ...
Vitamin D insufficiency prevalent among psoriatic arthritis suffers
2011-07-12
New research reports a high prevalence of vitamin D insufficiency and deficiency among patients with psoriatic arthritis. Seasonal variation in vitamin D levels was not observed in patients in southern or northern locations. The findings published today in Arthritis Care & Research, a journal of the American College of Rheumatology (ACR), also show no association between disease activity and vitamin D level.
Psoriasis is a common chronic skin disorder, likely caused by an autoimmune response, and is characterized by red scaly patches on the surface of the skin. When ...
SUMO defeats protein aggregates that typify Parkinson’s disease
2011-07-12
A small protein called SUMO might prevent the protein aggregations that typify Parkinson's disease (PD), according to a new study in the July 11, 2011, issue of The Journal of Cell Biology (www.jcb.org).
Insoluble protein clusters are the hallmarks of several neurodegenerative diseases. In PD, neurons harbor insoluble clumps of the protein alpha-synuclein. What triggers these protein pileups remains obscure. A possible clue for PD came when researchers overexpressed alpha-synuclein in human kidney cells and found that the protein was modified by the addition of the small, ...
Climbing the social ladder seems to lessen high blood pressure risk
2011-07-12
Social mobility - upwards - seems to curb the risk of developing high blood pressure among those born on the lower rungs of the ladder, suggests research published online in the Journal of Epidemiology and Community Health.
Being born into poor or disadvantaged backgrounds has been linked with an increased risk of high blood pressure, which is a known contributory factor to an increased risk of heart disease and stroke.
The authors wanted to see if that risk was affected by climbing up the social ladder across generations.
They used data from the Swedish Twin Registry ...
Contact allergies may trigger immune system defences to ward off cancer
2011-07-12
Contact allergies (reactions caused by direct contact with substances like common metals and chemicals) may help prime the immune system to ward off certain types of cancer, suggests research published today in the online only title BMJ Open.
Previous research has indicated that people with type 1 allergies, which include pollen and house dust mites, may be more or less likely to develop cancer. But it is not known if those with contact allergies to common metals such as nickel, and chemicals, might also be afforded protection against the disease.
The authors base ...
Dana-Farber study finds new points of attack on breast cancers not fueled by estrogen
2011-07-12
BOSTON ––– Although it sounds like a case of gender confusion on a molecular scale, the male hormone androgen spurs the growth of some breast tumors in women. In a new study, scientists at Dana-Farber Cancer Institute provide the first details of the cancer cell machinery that carries out the hormone's relentless growth orders.
The study, published the journal Cancer Cell on July 12, provides scientists with several inviting targets – cell proteins that snap into action in response to androgen – for future therapies. Drugs that block those proteins could slow or stifle ...
New study shows artery-opening procedure still widely used in spite of changed guidelines
2011-07-12
Despite changes in standard treatment practice guidelines issued by the American College of Cardiology, American Heart Association and the European Society of Cardiology several years ago, there has been no meaningful change in the nation's practice of opening completely blocked coronary arteries with balloons and stents in the days after a heart attack, according to a new study published in the July 11, 2011, issue of Archives of Internal Medicine. The new study concludes that cardiologists in the United States are still performing this procedure late after a heart attack. ...
Obese patients less likely to develop and die from respiratory distress syndromes after surgery
2011-07-12
Researchers have discovered that obese adults undergoing surgery are less frequently developing respiratory insufficiency (RI) and adult respiratory distress syndrome (ARDS), and that when they do, they are less likely to have fatal outcomes. The researchers say they have several theories of how obesity protects patients from mortality associated with RI/ARDS, and pinpointing the protective mechanism could help them develop interventions to help non-obese patients avoid adverse outcomes. The finding comes from a study published online ahead of print in the Journal of Intensive ...
Higher-protein diets can improve appetite control and satiety
2011-07-12
Park Ridge, Ill. (July 11, 2011) – A new study demonstrates that higher-protein meals improve perceived appetite and satiety in overweight and obese men during weight loss.(1) According to the research, published in Obesity, higher-protein intake led to greater satiety throughout the day as well as reductions in both late-night and morning appetite compared to a normal protein diet.
"Research has shown that higher-protein diets, those containing 18 to 35 percent of daily calorie intake from dietary protein, are associated with reductions in hunger and increased fullness ...
BGI contributes whole genome sequencing and bioinformatics expertise to potato genome research
2011-07-12
July 11, 2011, Shenzhen, China – BGI (previously known as the Beijing Genomics Institute), the largest genomic organization in the world, announced today that it was among the research organizations comprising the Potato Genome Sequencing Consortium (PGSC) that completed the genome sequence and analysis of the tuber crop potato, published as an Advance Online Publication in Nature.
This study marks an important milestone in Potato (Solanum tuberosum L.) genome research, revealing new insights into the evolutionary history of the potato genome, causes of inbreeding depression, ...
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