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Feinstein scientists identify abnormal disease pathway in dystonia

2011-04-13
MANHASSET, NY -- Scientists tried creating a laboratory model of idiopathic torsion dystonia, a neurological condition marked by uncontrolled movements, particularly twisting and abnormal postures. But the genetic defect that causes dystonia in humans didn't seem to work in the laboratory models that showed no symptoms whatsoever. Now, a team of scientists at The Feinstein Institute for Medical Research have figured out why and the finding could lead to ways to test novel treatments. Aziz M. Ulug, PhD, and his colleagues at the Feinstein's Center for Neurosciences wanted ...

Rainbow-trapping scientist now strives to slow light waves even further

Rainbow-trapping scientist now strives to slow light waves even further
2011-04-13
Buffalo, N.Y. – An electrical engineer at the University at Buffalo, who previously demonstrated experimentally the "rainbow trapping effect" -- a phenomenon that could boost optical data storage and communications -- is now working to capture all the colors of the rainbow. In a paper published March 29 in the Proceedings of the National Academy of Sciences, Qiaoqiang Gan (pronounced "Chow-Chung" and "Gone"), PhD, an assistant professor of electrical engineering at the University at Buffalo's School of Engineering and Applied Sciences, and his colleagues at Lehigh University, ...

Purpose Cash Advance Provides Loans of Up to $1,500 Online

2011-04-13
Payday loans ranging from $100 to $1,500 can now be borrowed online thanks to a cash advance system designed by online lending company, Purpose Cash Advance. The news provides relief to citizens looking for emergency financial assistance in Mississippi, Utah, South Dakota, Wisconsin, and Missouri. Interested borrowers can apply for payday loans online via the company's website. Purpose Cash Advance implemented the online cash advance process to provide citizens in the aforementioned states a quick, confidential and secure way to resolve difficult financial situations ...

Weight loss improves memory, according to Kent State researcher

Weight loss improves memory, according to Kent State researcher
2011-04-13
John Gunstad, an associate professor in Kent State University's Department of Psychology, and a team of researchers have discovered a link between weight loss and improved memory and concentration. The study shows that bariatric surgery patients exhibited improved memory function 12 weeks after their operations. The findings will be published in an upcoming issue of Surgery for Obesity and Related Diseases, the Official Journal of the American Society for Metabolic and Bariatric Surgery. The research report is also available online at www.soard.org/article/S1550-7289(10)00688-X/abstract. "The ...

Purpose Cash Advance Provides Online Payday Loans to Wisconsin Residents

2011-04-13
Purpose Cash Advance is pleased to announce that its online payday loans service is available to residents in the state of Wisconsin. Wisconsin joins Mississippi, Utah, South Dakota, and Missouri in the list of states where the company is committed to providing confidential, safe, and fast transactions. The company provides payday loans online that can be applied for via a simple application form requiring basic information. Once this information is verified, approval for the loan is granted in only a few seconds. The money is then deposited into the borrower's checking ...

Comprehensive UGA study reveals patterns in firefighter fatalities

Comprehensive UGA study reveals patterns in firefighter fatalities
2011-04-13
While the number of fires is on the decline, firefighter deaths are not —and a new University of Georgia study helps explain why. Researchers in the UGA College of Public Health found that cultural factors in the work environment that promote getting the job done as quickly as possible with whatever resources available lead to an increase in line-of-duty firefighter fatalities. "Firefighting is always going to be a hazardous activity, but there's a general consensus among firefighting organizations and among scientific organizations that it can be safer than it is," ...

Retired Expats' Worries about Weak Pound

2011-04-13
A survey by Lloyds TSB International has found that retired Britons stationed abroad are increasingly concerned about the falling value of the Sterling. - Concerns about reduced pensions income, new research finds - More than two thirds of expat pensioners now worried about currency fluctuations - Pensioners shifting bank accounts offshore as Sterling weakness continues Lloyds TSB International Banking has conducted a survey that shows a growing concern among expat pensioners about their money in the wake of the financial crisis. Over two thirds of respondents to ...

Report provides NASA with direction for next 10 years of space research

Report provides NASA with direction for next 10 years of space research
2011-04-13
COLUMBIA, Mo. ¬— During the past 60 years, humans have built rockets, walked on the moon and explored the outer reaches of space with probes and telescopes. During these trips in space, research has been conducted to learn more about life and space. Recently, a group of prominent researchers from across the country published a report through the National Academy of Sciences that is intended as a guide as NASA plans the next 10 years of research in space. Rob Duncan, the University of Missouri Vice Chancellor for Research, led the team that developed a blueprint for fundamental ...

Bruegger's Offers 2011 Tax Day Special

Brueggers Offers 2011 Tax Day Special
2011-04-13
This year, Bruegger's, a national bagel leader with more than 300 locations across the U.S., is offering IRS-weary guests its popular Big Bagel Bundles for just $10.40. Because of this year's tax day extension, Bruegger's will offer the deal from April 15 through April 18, 2011. Tax day may have lightened guests' wallets, but Bruegger's wants to help them enjoy America's Best Bagels at a special price. With 13 bagels and two tubs of Bruegger's cream cheese included, a Big Bagel Bundle for $10.40 is a big savings on a gift to share with friends and colleagues or a treat ...

Clinical study suggests estrogen levels and breast health can be altered

2011-04-12
WASHINGTON, D.C… April 11, 2011 … Researchers from Canada and the United States today told attendees of the Experimental Biology 2011 Scientific Meeting that they have uncovered a possible means of enabling women to favorably influence whether the estrogens in their bodies take a "beneficial path" or a "disease-potential" path. The researchers tested a nutritional combination of indole-3 carbinol, milk thistle extract, calcium-D-glucarate, Schizandra chinensis fruit extract, stinging nettle, lignans extracted from the Norway spruce, and vitamin D (a combination available ...

Cephalopods experience massive acoustic trauma from noise pollution in the oceans

2011-04-12
Noise pollution in the oceans has been shown to cause physical and behavioral changes in marine life, especially in dolphins and whales, which rely on sound for daily activities. However, low frequency sound produced by large scale, offshore activities is also suspected to have the capacity to cause harm to other marine life as well. Giant squid, for example, were found along the shores of Asturias, Spain in 2001 and 2003 following the use of airguns by offshore vessels and examinations eliminated all known causes of lesions in these species, suggesting that the squid deaths ...

Corticosteroid use during pregnancy not linked to facial clefts in infants

2011-04-12
The use of corticosteroids during pregnancy does not appear to be associated with an increased risk of orofacial clefts in infants, according to an article in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj101063.pdf. Many previous studies have shown associated risks with use of oral corticosteroids, although they were small studies. Corticosteroids are used for asthma, allergies, eczema and psoriasis, autoimmune diseases and cancer. Use of corticosteroids during pregnancy has been associated with orofacial clefts ...

Obesity may shut down circadian clock in the cardiovascular system

2011-04-12
WASHINGTON, DC – Obese individuals typically suffer more medical problems than their leaner counterparts. They are more likely to be diagnosed with insulin resistance, diabetes, increased stress hormones, hypothyroidism, and sleep apnea. Researchers at the Georgia Health Sciences University in Augusta have also found the potential for something else, using an animal model. They have found that a master clock gene – which regulates the cardiovascular system – does not fluctuate regularly as it does in non-obese animals. This means that a key gene clock of the cardiovascular ...

UCSF scientists discover link between inflammation and pancreatic cancer

2011-04-12
Solving part of a medical mystery, researchers at the University of California, San Francisco have established a link between molecules found in an inflamed pancreas and the early formation of pancreatic cancer – a discovery that may help scientists identify new ways to detect, monitor and treat this deadly disease. Scientists have known for many years that pancreatitis, a painfully inflamed pancreas, is a common risk factor for pancreatic cancer – along with things like smoking and diet. But nobody knew exactly why. Now the UCSF team, led by Matthias Hebrok, Ph.D., ...

Space jets in a bottle

2011-04-12
By creating space-like conditions in a slim 4m vessel, Italian researchers have helped confirm the behaviour of astrophysical jets – streams of charged particles shot out by supermassive black holes and young stars, which stretch several hundred thousand light years across space. The streams of initially charged particles – known as astrophysical jets - which can travel close to the speed of light have previously only been understood through computer simulations but are now being brought to life in lab-produced vacuums. Research published today, Tuesday, 12 April, in ...

Social wasps show how bigger brains provide complex cognition

Social wasps show how bigger brains provide complex cognition
2011-04-12
Across many groups of animals, species with bigger brains often have better cognitive abilities. But it's been unclear whether overall brain size or the size of specific brain areas is the key. New findings by neurobiologists at the University of Washington suggest that both patterns are important. The researchers found that bigger-bodied social wasps had larger brains and devoted up to three times more of their brain tissue to regions that coordinate social interactions, learning, memory and other complex behaviors. Within a species, queens had larger central processing ...

Haiti cholera epidemic could have been blunted with use of mobile stockpile of oral vaccine

2011-04-12
SEATTLE – Had a large stockpile of oral cholera vaccine been available and deployed to inoculate the majority of Haitians most at risk after the outbreak following last year's earthquake, the illness and death from the cholera epidemic could have been reduced by about half, according to new research. The findings, by Ira Longini, Ph.D., and colleagues in the Vaccine and Infectious Disease Division of Fred Hutchinson Cancer Research Center, are published in the April 11, 2011 early edition of the Proceedings of the National Academy of Sciences. Using computer models ...

Scientists ignore cultural barriers to find the cause of a rare disease

2011-04-12
CAMBRIDGE, Mass (April 11, 2011)—In a research collaboration blind to affairs of politics, ethnicity, and religion, an international team led by Israeli scientists has identified the genetic cause of a neurological disorder afflicting members of a Palestinian family. By combining the latest genome sequencing technology with a sophisticated "guilt-by-association" technique known as disease-network analysis, the team from Whitehead Institute, Cold Spring Harbor Laboratory, and Hadassah Medical Center in Jerusalem has found a heretofore unknown genetic mutation responsible ...

Nasal spray vaccines more effective against flu

2011-04-12
Nasal vaccines that effectively protect against flu, pneumonia and even bioterrorism agents such as Yersinia pestis that causes the plague, could soon be a possibility, according to research presented at the Society for General Microbiology's Spring Conference in Harrogate. Professor Dennis Metzger describes how including a natural immune chemical with standard vaccines can boost their protective effect when delivered through the nose. The respiratory tract is a major entry site for various viral and bacterial pathogens. However there are few approved vaccines that can ...

Is the wrist bone connected to heart risk?

2011-04-12
Measuring the wrist bone may be a new way to identify which overweight children and adolescents face an increased risk of developing cardiovascular disease, according to research in Circulation: Journal of the American Heart Association. "This is the first evidence that wrist circumference is highly correlated to evidence of insulin resistance," said Raffaella Buzzetti, M.D., senior study author and professor in the Department of Clinical Sciences at "Sapienza" University of Rome, Italy. "Wrist circumference is easily measured and if our work is confirmed by future studies, ...

Diesel-engine exhaust filter reduces harmful particles by 98 percent

2011-04-12
A commercially available particle trap can filter microscopic pollutants in diesel-engine exhaust and prevent about 98 percent of them from reaching the air, according to research reported in Circulation: Journal of the American Heart Association. Inhaling exhaust particles increases the risk of dying from heart and lung diseases. Air pollution, including diesel exhaust as a major contributor, causes 800,000 premature deaths annually in the world, according to the World Health Organization. "This study focused on cardiovascular effects in men exposed in the laboratory ...

Bacteria in wasp antennae produce antibiotic cocktails

Bacteria in wasp antennae produce antibiotic cocktails
2011-04-12
Bacteria that grow in the antennae of wasps help ward off fungal threats by secreting a 'cocktail' of antibiotics explains a scientist at the Society for General Microbiology's Spring Conference in Harrogate. Dr Martin Kaltenpoth describes how this is the first known example of non-human animals using a combination prophylaxis strategy similar to the one used in human medicine. This discovery could help us find novel antimicrobials for human use and lead to more effective strategies for using them. Female beewolf digger wasps cultivate symbiotic Streptomyces bacteria ...

Combating plant diseases is key for sustainable crops

Combating plant diseases is key for sustainable crops
2011-04-12
Climate change is likely to make plants more vulnerable to infectious disease, which will threaten crop yield and impact on the price and availability of food. Dr Adrian Newton, presenting his work at the Society for General Microbiology's Spring Conference in Harrogate, explains how exploiting diversity in crops is the best option to improve food security in a changing climate. Pest and disease management has helped double food production in the last 40 years, but 10-16% of the global harvest is still lost to plant diseases each year costing an estimated US$220 billion. ...

Vitamin D may help reduce heart risk in African-Americans

2011-04-12
WASHINGTON – In recent years supplementation with Vitamin D has been shown to reduce the risk of cardiovascular disease (CVD) in people who are deficient in the vitamin. Now new research from the Georgia Prevention Institute at Georgia Health Sciences University in Augusta indicates that supplementation with the "sunshine vitamin" may be particularly beneficial for overweight African-American adults, a population at increased risk for both CVD and Vitamin D deficiency. According to Ryan A. Harris, PhD, assistant professor, the Georgia team's research suggests that Vitamin ...

Women's voices remain steady throughout the month

2011-04-12
WASHINGTON – In recent years several studies have suggested that women's voices change at different times over the menstrual cycle, with the tone rising as ovulation approaches. Now a study conducted by researchers at the West Texas A&M University in which women's voices were subjected to computerized acoustical analysis contradicts those findings. After assessing 175 samples provided by 35 study participants at various points throughout the menstrual cycles, the researchers say that changes in hormonal status have no significant impact on eight distinct voice parameters. Neal ...
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