An international team of researchers from Leeds, London and Berlin has discovered more about the function of muscle stem cells, thanks to next-generation DNA sequencing techniques. The work, which was co-led from the University of Leeds' School of Medicine and the Charité, Berlin, is published this week in the journal Nature Genetics. The researchers investigated several families whose children suffered from a progressive muscle disease. The children developed severe weakness of the body's muscles and the diaphragm - the main breathing muscle - making them dependent ...

VIDEO: Click on the video above to see how the dots create a sense of moving forward straight ahead, to the right, and to the left. Click here for more information. The human brain is bombarded with a cacophony of information from the eyes, ears, nose, mouth and skin. Now a team of scientists at the University of Rochester, Washington University in St. Louis, and Baylor College of Medicine has unraveled how the brain manages to process those complex, rapidly changing, and often ...

A new study led by University of British Columbia researchers reveals how the effect of climate change can further impact the economic viability of current fisheries practices. "Fisheries are already providing fewer fish and making less money than they could if we curbed overfishing," says Rashid Sumaila, principal investigator of the Fisheries Economics Research Unit at UBC and lead author of the study. "We could be earning interest, but instead we're fishing away the capital. Climate change is likely to cause more losses unless we choose to act." Partly supported ...

JUPITER, FL -- Inspired by natural products, scientists on the Florida campus of the Scripps Research Institute have created a new class of small molecules with the potential to serve as a rich foundation for drug discovery. Combining the power of synthetic chemistry with some advanced screening technologies, the new approach could eventually expand by millions the number of provocative synthetic compounds available to explore as potential drug candidates. This approach overcomes substantial molecular limitations associated with state-of-the-art approaches in small molecule ...

Attorney Daniel D. Horowitz III, a partner at Abraham, Watkins, Nichols, Sorrels, Agosto & Friend in Houston, Texas, recently spoke to students at the University of Texas (UT) on the dangers of hazing in the Greek community. As a member of the board of directors of UT's Silver Spurs Alumni Association, Mr. Horowitz returns every semester to UT to speak with the incoming and active members of the Silver Spurs. "The purpose of the meeting is to discuss hazing, alcohol consumption, individual responsibility and accountability, as well as becoming a leader of the ...

Super 8 Monroe North Carolina Hotel offers convenient lodging to alumni, parents and guests attending the annual Wingate University Choirs Christmas Concert: Behold the Star. The event will take place at 7:30pm on Tuesday, November 29, 2011 at the 554-seat Hannah Covington McGee Theater in The George A. Batte, Jr. Fine Arts Center. Admission is free. Conducted by Dr. Kenney Potter, director, Behold the Star will include four university choirs: University Singers, Chamber Choir, Women's Choir and Men's Choir. Their holiday concert will feature many seasonal favorites ...

Archaeologists typically record and analyse the traces of past human activities. The caves of Lascaux in southern France are celebrated as a place where early humans made their marks on cave walls. The cave is now protected, and an exact replica is what the public now encounter. But a new study by archaeologists has been examining marks made much more recently -- graffiti by the Sex Pistols now discovered on the walls of the flat the punk group rented in London in the mid-1970s. The authors of a paper in the latest issue of the journal Antiquity argue that both are pieces ...

SOUTH SAN FRANCISCO, CA -- A novel antibacterial protein targeted against E. coli O157:H7 may offer a way to prevent or treat serious food-borne bacterial infections, as demonstrated in a study published in the December issue of Antimicrobial Agents and Chemotherapy. Results in an animal model of E. coli infection showed that the orally administered protein, developed by AvidBiotics, Inc., could prevent or treat E. coli O157:H7-induced diarrhea and intestinal inflammation when administered either on a preventative basis or after the onset of diarrhea. Moreover, animals ...

Hampton Inn Spartanburg Hotel - North I-85, offers close lodging to holiday shoppers attending the Gaffney Premium Outlets After-Thanksgiving Sale. Their biggest sale of the year, the event will take place, Friday, November 25 - Sunday, November 27, 2011 and will include: - Outstanding holiday savings - Extended holiday hours - Midnight Madness -- most stores open their doors at midnight right after Thanksgiving - Select stores opening at 10 and 11pm on Thanksgiving Day - Holiday Concert Series Presented by Coca-Cola on Sunday, November 27 Gaffney Premium Outlets ...

Hampton Inn Hotel Gaffney offers convenient lodging to visitors attending 2011 Christmas festivities at Limestone College in historic downtown Gaffney, South Carolina. An old fashioned Christmas celebration, the event will begin on Friday, December 2 at 5pm with Christmas on Limestone. This includes the lighting of the City Christmas Tree, candlelight tours, live music at the Michael Gaffney Log Home, caroling, sidewalk art, and youth and adult choir performances. Then, on Saturday, December 3 at 5pm guests can enjoy Christmas on Campus. Christmas on Campus is a 27th ...

Nobody likes a bully. Especially when that bully is the Internal Revenue Service! If you have unpaid taxes, the IRS has the power to not only levy your bank accounts but also to attach wage garnishments and levies against your employer and clients if you are self-employed. Talk about adding insult to injury! Carl (Escondido, California) was in this exact predicament when he finally made a desperate call to Blue Tax to ask for help. Carl had an IRS balance of roughly $30,000 for 2006 and 2008, not to mention three attached client invoice garnishments. Additionally, Carl's ...

eloquii by The Limited is a full-figured clothing line that celebrates a woman's sense of style, respects her curves and offers uncompromising fit, quality and comfort. eloquii unveiled their denim collection earlier this month, with the fundamental belief that every woman deserves great fashion. This line has been created to give plus size women the fashionable jeans with a perfected fit that they have been longing for. Each silhouette in the eloquii by The Limited denim collection has been designed from start to finish complementing a woman's body type, with careful ...

Cyber-Duck, an award-winning digital agency has been awarded the top honour in the Travel/Tourism category at the Interactive Media Awards for the design and build of The Far Horizons website, launched earlier in the year. Tours offered by the company give tourists the opportunity to enjoy quality wildlife and community tourism experiences in Rwanda, Uganda and Kenya, such as tracking Mountain Gorillas, rafting the River Nile or seeing Lions and Elephants in their natural habitat. The award was presented as 'Best in Class' and scored a highly impressive 481 points ...

ChristmasHoliday2011.com just made Christmas shopping easier for everyone this year with a new Facebook page for the Christmas Holiday 2011 season. The new Facebook page contains news articles, shopping tips, best gift ideas, Christmas recipes, hottest gifts and decorating ideas to help make this Christmas the best ever. ChristmasHoliday2011.com has so far received excellent reviews with most people enjoying the Christmas shopping stories on the page, such as the story about a Christmas fairy who was fired after cursing on the job. The woman claimed that she cursed out ...

Cruise.com, one of the Internet's largest cruise sellers, is offering its annual Black Friday Cruise Sale, featuring exceptional values on many of the major cruise lines to favorite destinations worldwide. The special sale is scheduled to begin at 8:00 AM on Friday, November 25th. Space for these deals is limited and will be offered on a first come first serve basis. To book these deals call 866-401-0895. Cruise.com's special Black Friday Cruise Sale features some of the best cruise deals to many exciting places such as the Caribbean, Europe, Alaska and South America ...

Two proteins conspire to promote a lethal neurological disease, according to a study published online this week in the Journal of Experimental Medicine (www.jem.org). Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating neurodegenerative disorder that results in progressive loss of motor function and ultimately death. More than 90% of ALS cases have no known genetic cause or family history. However, in some patients, spinal cord cells contain unusual accumulations of a protein called TDP-43. Jean-Pierre Julien and colleagues at ...

Breast cancer patients often wonder what their daughters might do to reduce their risk of also developing cancer. Are there dietary intakes or behaviors that can be modified by their daughters to lower their own chances of getting the disease? A new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society, sought information relevant to this question. Dr. Catherine Berkey, a biostatistician at Brigham & Women's Hospital and Harvard Medical School in Boston, led a team that investigated childhood and adolescent risk factors for benign ...

Adding to research linking alcohol to breast cancer risk, a new study from Washington University School of Medicine in St. Louis shows that adolescent girls with a family history of breast disease — either cancer or the benign lesions that can become cancer – have a higher risk of developing benign breast disease as young women than other girls. And unlike girls without a family history, this already-elevated risk rises with increasing alcohol consumption. "The most common question we hear from women with a family history of breast disease is how can we prevent breast ...

Childhood aggression is strongly linked to poorer health in adults and to higher use of health services, according to a new study in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/site/embargo/cmaj091830.pdf. Researchers from Université de Sherbrooke and Concordia University, Quebec, the University of California (Davis) and the University of Ottawa looked at data from the Concordia Longitudinal Risk Project to determine the impact of childhood aggression on health service usage in adulthood. The Concordia Longitudinal Risk Project ...

Canada should establish a vaccine seroepidemiology surveillance network to better understand the effectiveness of vaccination programs, according to an analysis in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/site/embargo/cmaj110506.pdf. Many countries, in Europe for example, have well-established national serosurveillance programs, despite differing vaccination practices. Canada, however, lacks a coordinated serosurveillance program despite the country's strong vaccination programs and support systems. A serosurveillance program ...

Natural health products and medicinal foods should be subject to the same regulations as pharmaceutical drugs to ensure safety and efficacy, states an editorial in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/site/embargo/cmaj111739.pdf. While pharmaceutical drugs are subject to rigorous evaluation and must provide significant evidence of their therapeutic effects and that the benefits outweigh risks, natural health products in Canada are not. Many contain active pharmacological substances that can have potent effects and interactions ...

Nearly a fifth of all Americans 12 years or older have hearing loss so severe that it may make communication difficult, according to a new study led by Johns Hopkins researchers and published in the Nov. 14 Archives of Internal Medicine. The findings, thought to be the first nationally representative estimate of hearing loss, suggest that many more people than previously thought are affected by this condition. Study leader Frank Lin, M.D., Ph.D., an assistant professor with dual appointments in both the Department of Otolaryngology-Head & Neck Surgery at the Johns Hopkins ...

Contact Michelle Geis 254-706-348-938 mgeis@burnesscommunications.com Burness Communications Additional contacts: Jonathon Rees 27-76-185-1827 Jonathon@proofcommunication.com Michael Victor 27-728-434-343 m.victor@cgiar.org Climate change in Africa's river basins could impede continent's farm transformation efforts Experts at global water forum warn climate shifts will increase water pressure on already-stressed Limpopo, Nile and Volta river basins, increase cross-border water conflicts Tshwane, South Africa -- Climate change could significantly ...

A novel study in twins found that exposure to trichloroethylene (TCE) -- a hazardous organic contaminant found in soil, groundwater, and air -- is significantly associated with increased risk of Parkinson's disease (PD). Possibility of developing this neurodegenerative disease is also linked to perchloroethylene (PERC) and carbon tetrachloride (CCI4) exposure according to the study appearing today in Annals of Neurology, a journal published by Wiley-Blackwell on behalf of the American Neurological Association and Child Neurology Society. The National Institute of Neurological ...

Glioblastoma multiforme (GBM) is the most common malignant brain cancer in humans. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant to current therapies. A team of researchers -- led by Bo Hu and Shi-Yuan Cheng, at the University of Pittsburgh Cancer Institute, Pittsburgh -- has now identified a molecular pathway that drives the aggressive cancerous nature of a substantial proportion of glioblastomas; specifically, those that overexpress the protein PDGFR-alpha. This pathway could represent a new therapeutic ...