A study from the Swedish medical university Karolinska Institutet has shown that the body's ability to break down medicines may be closely related to exposure to sunlight, and thus may vary with the seasons. The findings offer a completely new model to explain individual differences in the effects of drugs, and how the surroundings can influence the body's ability to deal with toxins. The study will be published in the scientific journal Drug Metabolism & Disposition and is based on nearly 70,000 analyses from patients who have undergone regular monitoring of the levels ...

Milan, Italy, 9 March 2011 – The Nobel prize-winning physicist Richard Feynman once wrote in his autobiographical book (What do you care what other people think?): "When I see equations, I see letters in colors - I don't know why […] And I wonder what the hell it must look like to the students." This neurological phenomenon is known to psychologists as synaesthesia and Feynman's experience of "seeing" the letters in colour was a specific form known today as "grapheme-colour" synaesthesia. What is perhaps most puzzling about this condition is that people actually claim to ...

MINNEAPOLS / ST. PAUL (March 9, 2011) – University of Minnesota researchers are using salmonella – the bacteria commonly transmitted through food that sickens thousands of U.S. residents each year – to do what was once unthinkable: help people. U of M Masonic Cancer Center researchers believe salmonella may be a valuable tool in the fight against cancer in organs surrounding the gut – such as the liver, spleen, and colon – since that's where salmonella naturally infects the body. Researchers want to "weaponize" salmonella, allowing the bacteria to then attack cancer ...

Cardiff University astronomers believe that a young star's long "napping" could trigger the formation of a second generation of smaller stars and planets orbiting around it. It has long been suspected that the build up of material onto young stars is not continuous but happens in episodic events, resulting in short outbursts of energy from these stars. However, this has been largely ignored in models of star formation. Now, by developing advanced computer models to simulate the behaviour of young stars, Cardiff University Astrophysicists Dr Dimitris Stamatellos and ...

The reduced risk of colorectal cancer associated with taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) may be confined to individuals already at risk because of elevations in a particular inflammatory factor in the blood. In a paper in the March issue of Gastroenterology, investigators from Massachusetts General Hospital (MGH) and Dana-Farber Cancer Institute report finding that higher baseline levels of a novel inflammatory marker indicated increased risk of developing colorectal tumors and also predicted who might benefit from taking aspirin or NSAIDs. ...

Milan, Italy, 9 March 2011 – Consider the simple situation in which you are walking around the kitchen and decide to pick up your own cup of tea, which is identical to others lying on the table. Your brain chooses the correct cup of tea by using different types of information that you have stored about the position of the cup in relation to the kitchen table. The information can be represented in qualitative terms (left, right, above, below) or quantitative terms (distances and angles). Previous studies have claimed that the brain's left hemisphere is critical for processing ...

Milan, Italy, 9 March 2011 – Human social interactions are shaped by our ability to recognise people. Faces and voices are known to be some of the key features that enable us to identify individual people, and they are rich in information such as gender, age, and body size, that lead to a unique identity for a person. A large body of neuropsychological and neuroimaging research has already determined the various brain regions responsible for face recognition and voice recognition separately, but exactly how our brain goes about combining the two different types of information ...

A history of alcohol abuse significantly impacts quality of life for patients after liver transplant, according to researchers at Henry Ford Hospital. "Transplant recipients with alcoholic cirrhosis experienced less improvement in physical quality of life and reported greater pain and physical limitations than non-alcoholics after transplant surgery," says Anne Eshelman, Ph.D., Henry Ford Behavioral Health Services, lead author of the study. "Understanding alcoholic and nonalcoholic patients' post-transplant change in quality of life may assist in treatment planning. ...

Increased imports often mean cheaper products for EU consumers and greater opportunities for producers in other countries to export their products, but also increased competition for EU producers. "I have compared various product groups and found that the effects of a reduction in tariffs would be different for fruit and vegetables and for cereals", says Cecilia Hammarlund, who is behind the report Handel med hinder – effekter av tullar på EU:s jordbruksimport (Trade with obstacles – effects of tariffs on EU agricultural imports). The study shows that an average reduction ...

As many as 100 million Americans may currently be misclassified as having abnormal blood pressure, according to Dr. Brent Taylor from the Veterans Affairs Health Care System in Minneapolis and the University of Minnesota and his colleagues. Their findings1 show that these people are not actually more likely to die prematurely than those with 'normal' blood pressure, i.e. below 120/80. Taylor and colleagues' article in the Journal of General Internal Medicine², published by Springer, also shows that in those under 50, diastolic blood pressure* is the more important predictor ...

Our brains process many more stimuli than we become aware of. Often images enter our brain without being noticed: visual information is being processed, but does not reach consciousness, that is, we do not have an impression of it. Then, what is the difference between conscious and unconscious perception, and can both forms of perception be changed through practice? These questions are important not only for basic research, but also for the treatment of patients with perceptual deficits due to brain lesions e.g. following a stroke. Scientists at the MPI for Brain Research ...

For people, being touched can initiate many different reactions from comfort to discomfort, from intimacy to aggression. But how might people react if they were touched by a robot? Would they recoil, or would they take it in stride? In an initial study, researchers at the Georgia Institute of Technology found people generally had a positive response toward being touched by a robotic nurse, but that their perception of the robot's intent made a significant difference. The research is being presented today at the Human-Robot Interaction conference in Lausanne, Switzerland. "What ...

Quebec City, March 9, 2011 – Another step has been taken in matter imaging. By using very short flashes of light produced by a technology developed at the national infrastructure Advanced Laser Light Source (ALLS) located at INRS University, researchers have obtained groundbreaking information on the electronic structure of atoms and molecules by observing for the first time ever electronic correlations using the method of high harmonic generation (HHG). Made by a team of researchers from the Energy, Materials, and Telecommunications Center of INRS and the National Research ...

This release is available in Spanish. U.S. Department of Agriculture (USDA) scientists are working to give melon growers some relief from cucurbit yellow stunting disorder virus, or CYSDV. In 2006, Agricultural Research Service (ARS) plant pathologist Bill Wintermantel with the U.S. Agricultural Research Station in Salinas, Calif., and university colleagues identified the plant disease that growers in California's Imperial Valley and nearby Yuma, Ariz., noticed was spreading through their cucurbit fields. Cucurbit crops affected included cantaloupe and honeydew melons. ARS ...

This release is available in German. Proteins are the most important functional biomolecules in nature with numerous applications in life science research, biotechnology and medicine. So how can they be modified in the most effective way to attain certain desired properties? In the past, the modifications were usually carried out either chemically or via genetic engineering. The team of Professor Arne Skerra from the TUM Chair of Biological Chemistry has now developed a more elegant combined solution: By extending the otherwise universal genetic code, the scientists are ...

To the surprisingly inventive uses for banana peels — which include polishing silverware, leather shoes, and the leaves of house plants — scientists have added purification of drinking water contaminated with potentially toxic metals. Their report, which concludes that minced banana peel performs better than an array of other purification materials, appears in ACS's journal Industrial & Engineering Chemistry Research. Gustavo Castro and colleagues note that mining processes, runoff from farms, and industrial wastes can all put heavy metals, such as lead and copper, into ...

Scientists are reporting an "important step" toward development of a universal blood product that would eliminate the need to "type" blood to match donor and recipient before transfusions. A report on the "immunocamouflage" technique, which hides blood cells from antibodies that could trigger a potentially fatal immune reaction that occurs when blood types do not match, appears in the ACS journal, Biomacromolecules. Maryam Tabrizian and colleagues note that blood transfusions require a correct match between a donor and the recipient's blood. This can be a tricky proposition ...

In its 27th survey of American spending priorities since 1973 conducted as part of its General Social Survey (GSS), NORC at the University of Chicago Wednesday released a report on its most recent findings. By a notable margin, education and health care were the top two spending priorities of Americans. And Americans are consistent in that: those two categories have finished in the top two in each of the ten surveys since 1990. The spending priorities report is derived from recently released data of the 2010 General Social Survey which NORC has conducted for forty years. ...

Scientists have developed a programmable "molecular robot" — a sub-microscopic molecular machine made of synthetic DNA that moves between track locations separated by 6nm. The robot, a short strand of DNA, follows instructions programmed into a set of fuel molecules determining its destination, for example, to turn left or right at a junction in the track. The report, which represents a step toward futuristic nanomachines and nanofactories, appears in ACS's Nano Letters. Andrew Turberfield and colleagues point out that other scientists have developed similar DNA-based ...

Mom's comforting tuck-them-in-words — "Sleep tight, don't let the bedbugs bite"— is becoming an impossible dream for millions of people as the world experiences a resurgence of an ancient scourge that is fostering human misery, financial burdens and the risk of exposure to potentially toxic materials. That's the message from the cover story of the current edition of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine. In the article, C&EN News Editor William G. Schulz points out that bedbugs represent a growing epidemic that is difficult to control. The bugs ...

Scientists are untangling how the tiniest pollution particles – which we take in with every breath we breathe – affect our health, making people more vulnerable to cardiovascular and respiratory problems. While scientists know that air pollution can aggravate heart problems, showing exactly how it does so has been challenging. In a study published recently in the journal Environmental Health Perspectives, scientists showed that in people with diabetes, breathing ultrafine particles can activate platelets, cells in the blood that normally reduce bleeding from a wound, ...

WEST LAFAYETTE, Ind. - Hybrid plants with multiple genome copies show evidence of preferential treatment of the genes from one ancient parent over the genes of the other parent, even to the point where some of the unfavored genes eventually are deleted. Brian Dilkes, an assistant professor of genetics at Purdue University, worked with a team of scientists at the University of California Davis and University of Southern California to study the genome of Arabidopsis suecica, a hybrid species with four chromosome sets formed tens of thousands of years ago from a cross between ...

So-called model organisms have long been at the core of biomedical research, allowing scientists to study the ins and outs of human disorders in non-human subjects. In the ideal, such models accurately recapitulate a human disorder so that, for example, the Parkinson's disease observed in a rat model would be virtually indistinguishable from that in a human patient. The reality, of course, is that rats aren't human, and few models actually faithfully reflect the phenotype of the disease in question. Thus, in the strictest sense of the word, many "models" aren't truly ...

FINDINGS: Whitehead Institute scientists have created a method that uses the enzyme sortase A to site-specifically modify proteins. Using this technique, researchers were able to increase potency, slow the metabolism, and improve thermal stability of several proteins, including interferon alpha 2 (IFN-alpha 2) and granulocyte colony-stimulating factor 3 (GCSF-3). IFN-alpha 2 is used to treat a variety of diseases, including leukemia, melanoma, and chronic hepatitis C, while GCSF-3 (known as filgrastim and marketed as Neupogen®) is administered to patients with neutropenia. RELEVANCE: ...

Although thousands of people commit suicide worldwide each year, researchers and doctors do not have any method for evaluating a person's likelihood of thinking about or trying to commit suicide. An international group of scientists, in which the Hospital del Mar Research Institute (IMIM) has participated, has devised the first risk index in order to prevent suicides. "It is of key importance to identify suicidal thoughts among people at increased risk. The most important contribution that our study has made is an international risk index to estimate the likelihood of ...