Some of the most aggressive forms of breast cancer are more vulnerable to chemotherapy when it is combined with a new class of anti-cancer agent, researchers from the Walter and Eliza Hall Institute have shown. ABT-737 is one of a new class of anti-cancer agents called BH3 mimetics that target and neutralise the so-called Bcl-2 proteins in cancer cells. Bcl-2 proteins act to 'protect' the cells after they have been damaged by chemotherapy drugs, and prevent the cancer cells from dying. Professors Geoff Lindeman and Jane Visvader, who led the research with colleagues ...

The cupcake industry is reaching all time heights, with gourmet delicacies and unique cupcake boxes. CupcakeBoxesWholesale.org offers information, tips, tricks and examples of wholesale cupcake boxes that are as creative as the cupcakes they hold. "It's important to have a familiar look with your product branding," said John Allen, owner of the site. "Wholesale cupcake boxes help achieve that sense of familiarity." The website provides information, tips and resources for cupcake boxes wholesale that offer branding opportunities, save money and ...

topseos.com, an independent authority on search vendors has named the Best eCommerce Solutions for the month of July 2011. All the eCommerce SEO agencies recognized next to thousands of other E-Commerce SEO Firms have gone through a comprehensive process evaluated by a qualified and experienced team of researchers. Each E-Commerce SEO company has been evaluated and ranked accordingly to the best eCommerce SEO in the internet marketing industry. "Each company is put through our rigorous evaluation process and the best are chosen to be featured on our rankings. All ...

Doctors should be allowed to object to any procedure that conflicts with their personal, moral, or religious beliefs, reveals a survey of medical students, published in the Journal of Medical Ethics. Nearly half of respondents believed in the right of doctors to conscientiously object and refuse to treat a patient who wanted an abortion, contraceptive services, or who was drunk or high on drugs, or who wanted an intimate examination and was of the opposite sex. This right was more frequently expressed among Muslim medical students, the survey findings showed. The ...

In its commitment to promote the highest standards in workplace safety, Saudi Readymix became the first ready-mixed concrete company in Saudi Arabia to certify all of its factory managers with Occupational Safety and Health Administration (OSHA) accreditation. All participating managers took part in an intensive training program, which was conducted over a period of two weeks. Once the training was concluded, the participants had to undertake and pass a comprehensive exam to become OSHA certified. All Saudi Readymix factory managers passed. The same OSHA training and ...

Expressing breast milk by hand in the first days after birth is better for boosting breastfeeding rates among poorly feeding newborns than the use of a breast pump, indicates a small study published online in the Archives of Disease in Childhood. Currently, either method may be recommended for newborns who latch or suck poorly to encourage them to breastfeed, say the authors. They base their findings on 68 mums whose newborns were latching on to the nipple or sucking poorly 12 to 36 hours after birth. The mums were randomly assigned to either 15 minutes of using a ...

When the language used by financial analysts and reporters becomes increasingly similar the stock market may be overheated, say scientists. After examining 18,000 online articles published by the Financial Times, The New York Times, and the BBC, computer scientists have discovered that the verbs and nouns used by financial commentators converge in a 'herd-like' fashion in the lead up to a stock market bubble. Immediately afterwards, the language disperses. The findings presented at the International Joint Conference on Artificial Intelligence, Barcelona, Spain, on Tuesday ...

Shawn "ETCETERA" McClain plays the lead role of young musician, Shane "Preme" Davis who has Type-1 Diabetes. Preme, who has been seeing a sexy new girl Sasha (Anita Clay) who could easily be his soul-mate and right now he feels like a million dollars. It's his best friend Mike (James Lentini) that's holding the music together for him while he takes care of his health problems: what more could a man wish for... Mike, an ambitious manager, and would-be rap artist, has love for Shane like a brother, and would give up everything for him, but later begins ...

While LASIK has been available since the early 1990s, many people still have questions about the procedure. According to Dr. Joel Hunter, founder of Hunter Vision, Central Florida's exclusive 3D LASIK provider, following are the five most-asked questions. 1. Is it permanent? "Yes! It's safe, and the changes that the laser makes to the cornea are permanent," Dr. Hunter says. "It's true that as the eye ages, the natural lens inside the eye stiffens, causing a loss of near vision. However, with the advent of 'blended vision,' I am able to treat the eyes in ...

Which is better, a quick vertical jab on the buttock or the delicately soft entry of a blood sample? Waiting to find out "for what", some are already wondering "how" to use those tiny "molecular syringes" which are carbon nanotubes. With a diameter of less than one millionth of a millimetre (nanometre) and a maximum length of just a few millimetres, the first use that springs to mind when we think of this ethereal tubes - the smallest ever made by man - is as potential needles for injecting drugs or genes into sick cells. And if a syringe it is, we had better start thinking ...

The Eucalantica genus belongs to the relatively primitive micro-moth group, Yponomeutidae. Six new species have been described by Mr. Jae-Cheon Sohn from the University of Maryland, College Park, USA and Mr. Kenji Nishida from Universidad de Costa Rica, San José, Costa Rica and published in the open access taxonomy journal Zookeys. "Yponomeutid moths are important group in tracing the evolution of plant association in Lepidoptera. In spite of this importance, the family has been neglected by systematists and its biodiversity and phylogeny remain poorly understood" comments ...

From eye-catching billboards that proclaim, "I can be good without God," to a critically acclaimed movie at the Sundance Film Festival, atheists are going public with their beliefs like never before. This has some Christians hot under the collar, but the leader of one of America's leading evangelistic ministries is urging believers to keep their cool. Public opinion polling shows that the number of Americans who are unaffiliated with any religion is growing rapidly. Alpha USA president Gerard Long, called one of the "stars of the church-saving circuit" ...

Small-scale fisheries could pose a more serious threat to marine life than previously thought. Research led by the University of Exeter, published today (19 July) in the British Ecological Society's Journal of Applied Ecology, shows that tens of thousands of turtles from across the Pacific are being captured through the activities of small-scale fisheries. Focusing on fisheries in Peru, the study suggests that thousands of sea turtles originating from nesting beaches as far away as Australia, Costa Rica, Mexico and the Galapagos, are likely to be captured each year as ...

From July 18th, the first 6000 customers will be able to get instant 10% off at 4Media Software when they pay using PayPal. There are Over 200 video, audio, DVD, PDF, iPhone, iPod and iPad software for customers to choose from. http://www.mp4converter.net/discount-promotion-paypal.html 4Media announced this promotional event taking place from July 18th to September 17th, among the first 6000 customers to purchase from 4Media, will receive an instant 10% off discount on their orders when they choose to pay with PayPal. What's more, if they are among the top 50 to ...

New Zealand artist Davina Stephens will showcase some of her most recent works at an exhibition in Bali next month.   Entitled From Bali With Love, the installation at the Ganesha Gallery is set to feature pieces produced using a wide array of media, materials and techniques in an attempt by Stephens to leave the meaning of her art open to interpretation.   Although the true message behind each work is shrouded, they are designed to highlight the joy and relevance of the moment.   Described by the organisers as "intricate storyboards", the pieces tell a ...

The amount of money that hospitals spend on environmental services, such as cleaning and maintenance service is not as important in influencing patient satisfaction scores as the way the money is spent, according to Penn State researchers. "By focusing on improving the efficiency of operations, hospitals can contribute to hospital performance while also getting the most out of the financial investments they make toward support services," said Deirdre McCaughey, assistant professor of health policy and administration, who led the research team. The team, which also ...

Violin virtuoso Nigel Kennedy will make his contribution to this year's BBC Proms on Saturday August 6th.   The classical musician is due to appear at the Royal Albert Hall, where he will perform solo violin works by JS Bach.   With tickets priced from GBP4.50 to GBP19.50, the concert could be the perfect opportunity for London visitors to experience the magic of the Proms.   Running from Friday July 15th to Saturday September 10th, the event is often described as the world's greatest festival of classical music.   The Proms is now in its 117th year and continues ...

The Offspring will bring their vintage punk rock sound to the Zenith de Paris later this summer. Fans of the California-based four-piece have a chance to see them perform in the French capital on Wednesday August 31st and Thursday September 1st. Known for hits such as Self Esteem and Pretty Fly (For a White Guy), the band have recently been holed up in the studio working on their forthcoming new album. Due out in late 2011 or early 2012, the record will be their ninth studio LP and their first since 2008's Rise and Fall, Rage and Grace. In April this year, ...

AUGUSTA, Ga. – A thalidomide analog is shaping up as a safe, worthy opponent of sickle cell disease, Georgia Health Sciences University researchers report. Much like hydroxyurea, the only Food and Drug Administration-approved therapy for sickle cell, pomalidomide increases production of fetal hemoglobin which, unlike its adult counterpart, cannot take on the destructive sickle shape. In stark contrast, pomalidomide also preserves bone marrow function actually increasing proliferation of the cells that make oxygen-carrying red blood cells, GHSU researchers report in ...

Country music legend Dolly Parton is due to perform live at Liverpool's Echo Arena on Wednesday August 31st.   The chart-topping American singer will appear on Merseyside as part of her 39-date Better Day world tour, which gets underway in her home state of Tennessee this month.   Known for classic hits such as Jolene and 9 to 5, Parton is the most successful female country artist of all time.   She released her debut album in 1967 and has since enjoyed 25 number one singles on the Billboard country chart, as well as picking up seven Grammy Awards.   Parton is also ...

The Frankenheim Kino offers people visiting Dusseldorf the chance to watch films in a picturesque open-air setting on the banks of the Rhine.   It promises a unique movie-going experience, with guests invited to enjoy a spectacular view of the city's Altstadt skyline before they settle into their seats.   From Thursday July 21st to Sunday August 21st, the outdoor cinema on the Rheinterrasse will be showing a diverse programme of movies designed to cater to all tastes.   This summer's line-up includes The King's Speech, True Grit, Black Swan, The Hangover 2, Kung Fu ...

WASHINGTON -- People with personality traits of high neuroticism and low conscientiousness are likely to go through cycles of gaining and losing weight throughout their lives, according to an examination of 50 years of data in a study published by the American Psychological Association. Impulsivity was the strongest predictor of who would be overweight, the researchers found. Study participants who scored in the top 10 percent on impulsivity weighed an average of 22 lbs. more than those in the bottom 10 percent, according to the study. "Individuals with this constellation ...

People spending time in Tenby this summer may like to visit nearby Picton Castle for some family activities on Wednesday August 3rd.   The historical attraction is due to host a Family Fun Day with a Cowboys and Indians theme, providing youngsters with the chance to get dressed up and win special prizes.   Children can either turn up as their favourite character or design their costume once they arrive at the castle, where face-painting and balloon modelling will also be on offer.   A fancy dress parade will take place at approximately 15:30 BST and the day promises ...

VIDEO: This video shows time-lapse images of the “electric face” -- dynamic patterns of membrane voltage visible on the surface of the developing frog embryo. Click here for more information. MEDFORD/SOMERVILLE, Mass.--For the first time, Tufts University biologists have reported that bioelectrical signals are necessary for normal head and facial formation in an organism and have captured that process in a time-lapse video that reveals never-before-seen patterns of visible bioelectrical ...

Legendary rock vocalist Robert Plant is set to perform live in Berlin as part of his European tour this summer.   The former Led Zeppelin frontman will play the German capital's Zitadelle Spandau venue on Wednesday August 3rd, giving fans a chance to hear tracks from his latest album Band of Joy.   Known for possessing one of the most powerful voices in music, Plant has carved out a successful solo career since the death of drummer John Bonham brought the Led Zeppelin era to a close in 1980.   His recordings have embraced a diverse selection of influences, ranging ...