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Scientists shed light on what causes brain cell death in Parkinson's patients

2011-01-08
SAN ANTONIO (Jan. 7, 2011) — Just 5 percent of Parkinson's disease cases can be explained by genetic mutation, while the rest have no known cause. But a new discovery by researchers at The University of Texas Health Science Center San Antonio may begin to explain why the vast majority of Parkinson's patients develop the progressive neurodegenerative disease. This week in the Journal of Neuroscience, the researchers demystified a process that leads to the death of brain cells – or neurons – in Parkinson's patients. When researchers blocked the process, the neurons survived. The ...

MicroRNA-TP53 circuit connected to chronic lymphocytic leukemia

2011-01-08
HOUSTON - The interplay between a major tumor-suppressing gene, a truncated chromosome and two sets of microRNAs provides a molecular basis for explaining the less aggressive form of chronic lymphocytic leukemia, an international team of researchers reports today in the Jan. 4 edition of the Journal of the American Medical Association. "Our findings could reveal new mechanisms of resistance to chemotherapy among leukemia patients as this feedback mechanism could help us differentiate between patients with poor or good prognosis," said co-senior author George Adrian Calin, ...

Study shows promise for new drug to treat Fragile X

2011-01-08
The first drug to treat the underlying disorder instead of the symptoms of Fragile X, the most common cause of inherited intellectual disability, shows some promise according to a new study published in the January 5 issue of Science Translational Medicine. Researchers from Rush University Medical Center helped design the study and are now participating in the larger follow-up clinical trial. The data from the early trial of 30 Fragile X patients, found the drug, called AFQ056, made by Novartis Pharmaceuticals, helped improve symptoms in some patients. Patients who had ...

Blame the 'chaperone'

2011-01-08
A Jackson Laboratory research team led by Professor Patsy Nishina, Ph.D., has identified a mutation in a gene that's essential for correct protein-processing in cells. Defects in protein folding are associated with a variety of abnormalities and diseases. Cells don't come prefabricated, with pieces plunked down and tacked together like modular homes offloaded from trucks. The structural proteins that give cells shape, tubulin and actin (think beams and girders), are themselves subject to essential processing before they become part of the assembly. Proteins must be folded ...

Link between signaling molecules could point way to therapies for epilepsy, stroke, other diseases

2011-01-08
SAN ANTONIO (Jan. 7, 2010) — In the Old West, camps sent smoke signals across distances to share key developments or strategy. Likewise, two important signaling molecules communicate across nerve cells to regulate electrical and chemical activity, neuroscientists from the UT Health Science Center San Antonio reported today. The findings in rodent models have implications for potential future treatment of epilepsy, stroke and other problems, the researchers said. "We now have novel targets for therapeutic intervention for a range of neurological and cardiovascular diseases, ...

Prof. Erantha De Mel Receives The US President's Service Award

2011-01-08
Sri-Lankan born Psychologist / Cognitive Neuroscientist Prof. Erantha De Mel received the President's Call to Service Award at a ceremony held in Washington DC recently. This distinguished service award by President Barack Obama was presented to him for his outstanding services to the American community in the fields of Psychology and Psychotherapy. This lifetime achievement award was established in 2003 after President George W. Bush created the President's Council on Service and Civic Participation. It is given annually to individuals who have dedicated over 4,000 ...

GridBuddy: an award-winning cloud application for the Force.com platform

2011-01-08
Salesforce.com announced that AppBuddy's new application GridBuddy was recognized as one of the top 4 installed applications in the 'Hack into Dreamforce' contest. Awards were given to applications with the highest number of customer AppExchange software installs between 9/20/10 and 11/30/10 leading up to the annual Dreamforce conference. GridBuddy is a 100% native Force.com application that allows users to edit multiple related Salesforce objects using an Excel-like view. GridBuddy has a clean, simple-to-use interface for users to view one parent object with multiple ...

Start Your New Year With A Kick, Women Self-Defense Lessons

2011-01-08
In recent years, programs geared to women only have began to take popularity. From fitness kickboxing classes, boot camps, and women fitness clubs -- women only programs have taken off like a grand slam in baseball. Starting on February 7th, 2011, local martial arts and fitness school owner and instructor, Javier Lozano, Jr. will be teaching a series of 8 Week Women Self-Defense Courses throughout the year. These 8 week courses are designed to teach women the basic fundamentals of empty-hand self-defense by using effective strikes, kicks, and blocks to fend ...

Newly Announced Webinar Compares Agile Software Development from Nearshore and Farshore Viewpoints

2011-01-08
The benefits and risks of IT outsourcing to Latin America will be explored in-depth during a special one-hour webinar coming January 25th at 2 p.m. EST. "The Agile Alternative: What Does Mexico Have that India Doesn't?", hosted by the premiere IT offshoring blog - Nearshore Americas, examines the value proposition of relying on 'nearshore' partners to provide custom application development services. Register today by visiting: http://www.csvep.com/registration/view.php?id=123 Geared toward IT decision makers and managers responsible for software development, testing ...

FoodEnquirer.com - Celebrate The Oat Meal Month And Lower Your Cholesterol

2011-01-08
To start with, it is important that we clear things up. The oatmeal that will give you health benefits are those made from pure oak flakes. The instant oatmeals will do you more harm than good since they have much sugar in them; not to mention traces of preservatives. Having oatmeal for breakfast is a good way to pump you full of energy and start the day. Aside from giving you the boost you need, there are tons of benefits of eating oatmeal. This is why it became a favorite household food item. The first of the obvious benefits of eating oatmeal is it contains fiber, ...

Real World Leader's Institute Co-Founders Debora Mclaughlin And Donna Price, Launch Their Radio Show: Real World Leadership At Blogtalkradio.

2011-01-08
With today's economy and the unique needs of today's work force the face of leadership is changing. Authority driven leadership no longer works and current employee engagement statistics report that only 29% of today's workforce are engaged, reporting to work focused on meeting performance and business outcomes. Successful companies are focusing on educating leaders on employee engagement and current cutting edge leadership strategies to positively affect the bottom line. January 5th, 2011 Debora McLaughlin, CEO of Open Door Coaching and co-founder of The Real World ...

Wall Street Journal: Scoring Unlisted Jobs (80% of job openings are unlisted)

2011-01-08
Job boards are irresistible because they seemingly put everything within easy reach. Unfortunately, the majority of job hunters are competing for the same small pool of jobs and getting turned down. More than 80% of job openings are actually unlisted, says Steven Rothberg, founder of job website CollegeRecruiter.com in Minneapolis. This can be a good opportunity for outside candidates with research and networking skills since most companies will try to promote from within or rely on employee referrals. Look for signs: Keep up with what's going on in your industry. ...

Barnes & Noble is 'Hound Bound' with Brimstone and the Borderhounds

2011-01-08
Hound Comics is proud to formally announce that its flagship brand, "Brimstone and The Borderhounds" will officially be on the shelves of Barnes & Noble and Book World retail stores nationwide on Tuesday, January 11th! On this date, the brand new comic book will be available in bookstores as well as online worldwide via Amazon.com. Hot off the official launch signing held at Borders Books & Music (October 2010 - Westbury, NY) this past fall, the "Hounds" are excited their fans will have full access to their latest endeavor. "Brimstone and the Borderhounds" is a comic ...

K-12 Digital Menu Boards with Nutritional Labeling - Simple and Effective way to fight Obesity

2011-01-08
Epicure Digital, a leader in digital menu boards, presents the Epicure Digital Menu System with special emphasis on nutritional labeling at the California School Nutrition Association (CSNA) Annual Conference and Exhibition in Pasadena, California, January 14-15, 2011, Booth #415. Epicure Digital Systems is a digital menu board company uniquely integrating its expertise in software technology and food service operations and marketing to create digital signage products and services for the food service industry. Its core product is the Epicure Digital Menu System . Its ...

Brite Future Continues Expansion with New Branch in North Miami Beach

2011-01-08
Brite Future Plumbing, Inc., a leading provider of residential and commercial plumbing services in the South Florida area, recently established its newest branch in North Miami Beach, Florida. The new North Miami Beach Plumbers branch will act as a strategic center for sales and support services to the Dade County market. "The Brite Future North Miami Beach team consists of some of the most talented plumbing experts familiar with all areas of residential and commercial plumbing," said Cassandra Cordero, President of Brite Future Plumbing. "We are committed to meeting ...

New phase, new year of Yun Fitness Boot Camps begins January 4

2011-01-08
Boot camp founder and local fitness expert Jason Yun urges Columbus residents to join up, burn some serious fat, and make 2011 the year they truly lose the weight and keep it off. "Lots of people make New Year's resolutions to eat better and get in shape," says Yun. "Unfortunately, for many people, those goals are abandoned by the end of January. By joining a proven program that gets results fast, you'll stay motivated. You'll surprise yourself with how much you can accomplish and how much fun you'll have doing it." Yun Fitness Boot Camps are enjoyable and effective. ...

Michigan Coin Dealer Cash for Coins Launches New Website

2011-01-08
Michigan based Cash for Coins announces the launch of their new updated and interactive website http://www.SellMeCoins.com Their newly revised website offers updated information on historic and valuable coins, precious metals as well as current pricing and upcoming events or trainings. http://www.SellMeCoins.com is based in Michigan and facilitates out of state clients with their revolutionary CoinPak. Cash for Coins hired Michigan based Front Street PR to create their WordPress website and manage their social media and online marketing. The Cash for Coins new website ...

Abducted from society and denied freedom for over 20 years, Buffalonian making big waves for domestic violence awareness

2011-01-08
Imagine being a marionette. Your owner controls your every move and puts you away at the end of the night, when they are done with you. That was Suzanne Perry's actual life, for over 20 years; as she was controlled, belittled and beaten by her husband. After a final break and a vow to her children to never return to father, she now speaks before colleges, organizations to share her story and explain her mission to help others where she was failed. Recently recognized, published or posted with the National Coalition against Domestic Violence, the New York State and Erie ...

Blenz Coffee opens in Kamloops Starting the New Year with their eighth location in the Okanagan

2011-01-08
This franchise location will be operated by Branka Gajic and her son Nik, both who have completed their Blenz Coffee franchise training in Vancouver and Kelowna. "My family and I are delighted to have our Blenz Coffee business located in Kamloops," says Branka. "It is a community that we are proud to be part of. We love the coffee business, and we look forward to being part of the Kamloops business community." "We are very pleased that Branka Gajic has joined the Blenz family as the franchise partner and operator of the new Blenz Coffee store in Kamloops," commented ...

The Corporate Educator Releases New "Rev It Up Reading" Software

2011-01-08
The Corporate Educator LLC announced the re-launch of their popular online speed reading course for college students and business professionals called "Rev It Up Reading: Getting Up To Speed With What You Read" The newly designed program offers users an improved appearance, upgraded on-screen features and easier navigation over the previous version. The new course is now replacing the previous version available for registration at http://www.RevItUpReading.com . Rev It Up Reading is the brainchild of Abby Marks Beale, founder of The Corporate Educator. Her dream is that ...

Core Systems Summit Announces Agenda Details

2011-01-08
The CDM Media team announced today agenda details for the Core Systems Summit to be held April 14 -15, 2011 in Chicago, Illinois, with strategic content partner, Novarica, a research and advisory firm that provides information, insights, and perspective on markets, operations, and technology to financial services and insurance executives. The Core Systems Summit, to be held with strategic content partner, Novarica, is a two-day event for insurance technology executives from the Property & Casualty and Life & Annuity sectors. The event is an opportunity for attendees ...

Sims Recycling Solutions Precious Metal Division Receives OHSAS 18001 Certification

2011-01-08
Sims Recycling Solutions, North America's largest electronic scrap processor is pleased to announce that their precious metal recycling facility in Franklin Park, IL has become the eighth Sims Recycling Solutions facility in North America to achieve OHSAS 18001 certification. OHSAS 18001 is an international occupational health and safety management system standard to enable an organization to control its health and safety risks and improve its performance. OHSAS 18001 certification is the result of an audited-verification of the organization's management system to achieve ...

Top Quality SEO Services Through Efficient Landing Page Optimization Tactics

2011-01-08
Keyword Search Pros is no stranger to the field of internet marketing. The company offers competitive, tried and tested strategies for sure-fire success in the promotion of any product or service for businesses seeking for growth and expansion. One highly effective internet marketing strategy for any business is through creating a great landing page design. A landing page is a page where a visitor arrives at after clicking a provided link which may be on any site online. It could be from a pay per click advertisement or from a keyword search. As a direct marketing strategy, ...

The Auto Moto Introduces a New Three Wheel Scooter for the US Market

2011-01-08
The Auto Moto.com Corporation announced today the release of their highly anticipated roofless three wheel tilting scooter dubbed the "The Auto Moto Sport". The new design incorporates the same tilting capabilities as its predecessor and provides a fun and exhilarating ride. Since 2008, TheAutoMoto.com Corporation has been distributing the classic roofed version of their vehicle to dealers in US with much success. This new model is geared towards a younger generation of riders looking for a more sporty and maneuverable ride. The new Auto Moto Sport comes standard with many ...

Part 2 of "Shamans and Dreams" on January 11 "Why Shamanism Now?" Radio Show with Christina Pratt

2011-01-08
Streaming live on the Co-Creator Radio Network (www.co-creatornetwork.com) on Tuesday, January11, at 11 a.m. Pacific time/2 p.m. Eastern time, on her show "Why Shamanism Now?: A Practical Path to Authenticity," shaman and founder of the Last Mask Center for Shamanic Healing Christina Pratt tells listeners that Spirits produce dreams, but not necessarily all dreams. This is important because it means that there are potentially multiple spirits producing dreams, not just a single human soul. According to Pratt, spirits producing dreams can be: personal souls; helping spirits; ...
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