Upside Software Inc. announced it has been recognized as a leader amongst Contract Lifecycle Management (CLM) software providers in the report "The Forrester Wave: Contract Life-Cycle Management, Q2 2011" Forrester Research, Inc., June 2011. Vendors were evaluated on 113 criteria that examined each step of the contract life cycle and measured how each vendor performed against key determining factors. The report states "Upside Software provides an all-around excellent solution. Upside Software had the highest overall score in the evaluation with deep functionality ...

Researchers from the Institute of Food Research and The Genome Analysis Centre have published the genome sequence of a gut bacterium, to help understand how these organisms evolved their symbiotic relationships with their hosts. The relationship between gut bacteria and the gastrointestinal tract is one of IFR's main research areas. Key to understanding the role of bacteria in establishing and maintaining gut health is knowledge of how the very close relationship between the bacteria and their hosts has evolved to be mutually beneficial to both. One bacterial species, ...

Bethesda, MD—Adult stem cells and progenitor cells may not come with a clean genetic slate after all. That's because a new report in the FASEB Journal (http://www.fasebj.org) shows that adult stem or progenitor cells have their own unique "epigenetic signatures," which change once a cell differentiates. This is important because epigenetic changes do not affect the actual make up in a cell's DNA, but rather, how that DNA functions. Epigenetic changes have been shown to play a role in a wide range of diseases, including obesity, and have been shown to be heritable from mother ...

For the third straight year, MARK SYSTEMS has been named as one of the most influential technology providers in the residential construction marketplace. Mark Systems was included as one of the Constructech 50, the third year in a row that the Constructech Magazine has selected the company. Companies are judged on a variety of criteria , including having a strong product/service aimed at the construction industry, ongoing customer satisfaction and growth, as well as outreach and educational efforts for the construction industry, among others. According to the editors ...

Bethesda, MD—If you think nicotine receptors are only important to smokers trying to kick the tobacco habit, think again. New research published in the FASEB Journal (http://www.fasebj.org) suggests that these receptors also play an important role in social interaction and the ability to choose between competing motivations. Specifically, scientists from France show that the nicotinic receptors in the prefrontal cortex are essential for social interaction in mice and that this area of the brain is necessary for adapted and balanced social interactions to occur. This new ...

High frequency non-ionizing radiation, emitted by mobile phones, is redundantly matter of discussions. The effects of high frequency electromagnetic fields (HEFs) derived from mobile phones have been discussed since the 1950's. Neuroscientists from Bochum were now able to elucidate this question. For the first time, they provide proof that extremely high-powered electromagnetic fields (EMFs) indeed influence learning processes on the synaptic level within the brain, independent from other factors like stress. "For this effect, very high values are necessary. These do not ...

Bethesda, MD—A sizzling genetic discovery by Chinese scientists may one day allow pig tissue to be transplanted successfully into humans. Their research presented in the Journal of Leukocyte Biology (http://www.jleukbio.org) represents a major step forward toward filling the shortage of vital organs for human transplantation. At the core of their work, they showed that altering or overexpressing the human programmed death ligand-1 (PD-L1) molecule in the endothelial cells of pig arteries reduces the conditions that lead to rejection. This strongly suggests that humans could ...

Ground-level ozone is an air pollutant that harms humans and plants. Both climate and weather play a major role in ozone damage to plants. Researchers at the University of Gothenburg, Sweden, have now shown that climate change has the potential to significantly increase the risk of ozone damage to plants in northern and central Europe by the end of this century. "The increased risk of ozone damage to vegetation is mainly due to rising ozone concentrations and higher temperatures in the future," says Jenny Klingberg at the University of Gothenburg's Department of Plant ...

harlequins enigma toss their wizard robes with the release of dance album Octagon Volume 2 -- Night Pulse and the silhouette of Dr. Voodoo - out on CDBaby now. The album has been worked on mainly in harlequins enigma's home studio, but they used a helping hand on a difficult track. Guest starring artists on Octagon Version 2 is: Jean Michel Jarre, DJ Tiesto, Emma Watson, Katie Leung, Sara Jensen, Stale Riisnes, Jan reidar riisnes, svein tore hindenes & elin berge. full track index will be put up on our homepage asap. The full distribution package means the album ...

Researchers at the Sahlgrenska Academy, University of Gothenburg, have identified a series of novel proteins in human cerebrospinal fluid. The proteins, which carry specific sugar molecules, are found in greater concentrations in patients with dementia caused by Alzheimer's disease than in patients with dementia caused by other diseases. This gives hope for new forms of treatment in the future. Göran Larson is a professor at the Sahlgrenska Academy and one of the authors of the article published in the revered journal Proceedings of the National Academy of Sciences USA ...

Milan, Italy, 30 June 2011 – Differences in male and female behaviour are often subject to study. Women are known to be more verbally fluent, have better manual dexterity and are better at noticing things (like a new haircut). Men on the other hand often take less time parking their cars and have less trouble than women in navigating in a new city. The latter capacities, in which men tend to excel, are known as visuo-spatial abilities. A new study has demonstrated that men have a similar advantage in their hearing. The findings are published in the June 2011 issue of Elsevier's ...

Four patients now have new lungs thanks to a purpose-built machine used for the first time worldwide by Sahlgrenska University Hospital. Acquired for research at the Sahlgrenska Academy, University of Gothenburg, Sweden, the new machine will contribute to more lung transplants in the long term. Built by a company in Lund, the machine is used to assess and treat the function of donors' lungs before transplantation. While the lungs of many donors are of good quality, some can swell on account of the fluid that gathers in them, rendering them unsuitable for transplantation. ...

CAMBRIDGE, Mass. -- Suppose someone showed you a novel gadget and told you, "Here's how it works," while demonstrating a single function, such as pushing a button. What would you do when they handed it to you? You'd probably push the button. But what if the gadget had other functions? Would it occur to you to search for them, if your teacher hadn't alluded to their existence? Maybe, maybe not. It turns out that there is a "double-edged sword" to pedagogy: Explicit instruction makes children less likely to engage in spontaneous exploration and discovery. A study by MIT ...

Many animals have eyes that are incredibly complex – others manage without. Researchers at the University of Gothenburg have shown that sea urchins see with their entire body despite having no eyes at all. The study has been published in the scientific journal Proceedings of the National Academy of Sciences (PNAS). Most animals react to light and have developed a very sophisticated way of seeing complex images so that they can function in their surroundings. Good examples include insects' compound eyes and the human eye. Charles Darwin and other evolutionary biologists ...

City Bingo is always in the spirit of things and as such, the free bingo site has launched some bonuses for Father's Day. With Bingo Avenue running this weekend as well, this weekend could prove to be quite lucrative for discerning online bingo players. By using the exclusive promotional code, members can get themselves an 80% re-deposit bonus on Sunday. Weekends are rarely dull at City Bingo with the now famous Bingo Avenue Tournament and the special City Bingo guarantee jackpots games taking place. Saturday is all about the Big Wheel free bingo bonanza and Sunday's ...

The threat Asian carp pose to the Great Lakes community may be politically controversial, but pales in comparison to the costs and danger of continuing to wring hands over established facts. It's time, a Michigan State University fisheries expert says, to let science drive policy and put knowledge into action. "You know it's big when academics and the management community say we don't need five more years of study," said Bill Taylor, University Distinguished professor in global fisheries sustainability at Michigan State University and a member of MSU's Center for Systems ...

Bingo Liner, one of the top bingo sites in the UK are not only offering excellent bingo games, like Mega-bingo, 90 ball bingo and Sailboat Special, but they also offer an excellent variety of slots and other games on their website. With new bingo sites appearing all over the web each week, players are looking to find not only the best offers out there, but also to find established places that they can keep revisiting. While the bingo revolution is definitely here both offline and online, with no deposit bingo games becoming a great attraction for many on the Internet ...

CAMBRIDGE, Mass. -- For 50 years, the transistors on computer chips have been getting smaller, and for 50 years, manufacturers have used the same technique — photolithography — to make their chips. But the very wavelength of visible light limits the size of the transistors that photolithography can produce. If chipmakers are to keep shrinking chip features, they'll probably need to turn to other manufacturing methods. Researchers have long used a technique called electron-beam (or e-beam) lithography to make prototype chips, but standard e-beam lithography is much slower ...

McCusker & Company, a leading nationwide developer of warranty protection solutions for the commercial and consumer electronics industry, is proud to announce the addition of Neal Rutherford to the management team as the new Director of Business Development. Rutherford brings to his role more than 20 years of diverse sales and marketing experience. "Neal Rutherford is an outstanding addition to our rapidly expanding company," said McCusker & Company President Will L. McCusker. "He adds additional depth of extended warranty sales and relationship ...

EAST LANSING, Mich. — Evolutionary adaptation is often compared to climbing a hill, and organisms making the right combination of multiple mutations – both good and bad – can become the king of the mountain. A new study published in the Proceedings of the Royal Society B by BEACON researchers at Michigan State University suggests that the combined effect of multiple mutations working together can speed up this process. Through computer simulations, researchers at BEACON, a National Science Foundation-funded Science and Technology Center at MSU, were able to watch evolution ...

A study by Columbia Business School Professor Sheena Iyengar, S. T. Lee Professor of Business, Management, and Emir Kamenica, Associate Professor of Economics, University of Chicago Booth School of Business, found the more fund options an employee has to choose from when presented with 401k options deters he or she from enrolling in the plan. The professors conducted three experiments in order to determine how increasing the size of a choice set will impact the option the consumer will chose, evolving from earlier studies that have focused on whether increasing the number ...

ESA's Integral gamma-ray observatory has provided results that will dramatically affect the search for physics beyond Einstein. It has shown that any underlying quantum 'graininess' of space must be at much smaller scales than previously predicted. Einstein's General Theory of Relativity describes the properties of gravity and assumes that space is a smooth, continuous fabric. Yet quantum theory suggests that space should be grainy at the smallest scales, like sand on a beach. One of the great concerns of modern physics is to marry these two concepts into a single theory ...

29.06.2011 | Potsdam: The "Potsdam Gravity potato", as this representation of terrestrial gravity has become known, can for the first time display gravity variations that change with time. The seasonal fluctuations of the water balance of continents or melting or growing ice masses, i.e. climate-related variables, are now included in the modeling of the gravity field. "EIGEN-6C" is the name of this latest global gravity field model of the GFZ German Research Centre for Geosciences. It was recently calculated in Potsdam in cooperation with the Groupe de Recherche de Géodésie ...

(Boston) - Researchers from Boston University School of Medicine (BUSM) using a traditional Korean medicine, SO-CHEONG-RYONG-TANG (SCRT) that has long been used for the treatment of allergic diseases in Asia, found that SCRT treatment alleviates asthma-like pulmonary inflammation via suppression of specific chemokines or proteins. These findings appear online in the Annals of Allergy, Asthma & Immunology. Asthma is a unique form of chronic respiratory disease characterized by reversible airway obstruction and pulmonary inflammation. It represents one of the most common ...

London, the capital city of the UK, boasts of a wide range of hotels to its credit. There is a wide range of hotels near London that ranges from cheap to luxury. The hotels make the city a highly desired place among the tourists as well as business travellers. Among the various hotels located near the city the one that acts as an ideal destination for guests is the Lancaster gate accommodations. It is one of the premier hotels in the city that can be easily accessed from different parts of the city. There are a number of tourists attractions located close to the hotel. ...