Prescription drugs and their dosages may be standardized, but not every patient reacts to a medicine in the same way. The personal genetic characteristics of individuals and populations can explain why a specific prescription successfully treats one patient and not another, so medical researchers are adopting the new approach called "personalized medicine" and a Tel Aviv University lab is leading the way. Dr. Noam Shomron of Tel Aviv University's Sackler Faculty of Medicine is developing a new method for the advancement of personalized medicine, an expanding area of ...

Researchers at Queen's University have discovered how molecules in glass or plastic are able to move when exposed to light from a laser. The findings could one day be used to facilitate medicinal drug distribution by allowing doctors to control the time and rate at which drugs are delivered into the body. The drugs, in a solid plastic carrier, could be released through the body when exposed to light. Lead researcher Jean-Michel Nunzi, a professor in the departments of Chemistry and Physics, has determined that "molecular cooperation" is what allows the molecules to move ...

INDIANAPOLIS –A new study from the School of Science at Indiana University-Purdue University Indianapolis looks at how much African Americans and whites favor or prefer their own racial group over the other, how much they identify with their own racial group, and how positively they feel about themselves. The work, by Leslie Ashburn-Nardo, Ph.D., associate professor of psychology in the School of Science at IUPUI, looked at both consciously controllable sentiments and gut feelings about social stigma and found a significant difference in both groups between what people ...

Early detection is critical for improving cancer survival rates. Yet, one of the deadliest cancers in the United States, lung cancer, is notoriously difficult to detect in its early stages. Now, researchers have developed a method to detect lung cancer by merely shining diffuse light on cells swabbed from patients' cheeks. In a new clinical study, the analysis technique--called partial wave spectroscopic (PWS) microscopy--was able to differentiate individuals with lung cancer from those without, even if the non-cancerous patients had been lifetime smokers or suffered ...

Water ice on asteroids may be more common than expected, according to a new study that will be presented today at the world's largest gathering of planetary scientists. Two teams of researchers who made national headlines in April for showing the first evidence of water ice and organic molecules on an asteroid have now discovered that asteroid 65 Cybele contains the same material. "This discovery suggests that this region of our solar system contains more water ice than anticipated," said University of Central Florida Professor Humberto Campins. "And it supports the ...

PROVIDENCE, R.I. [Brown University] — Seemingly healthy adults, if they were abused or neglected during childhood, may suffer physiological consequences decades later. In research published online last week by the journal Neuropsychopharmacology, a team led by psychiatrists at Brown University and Butler Hospital found that healthy adults who reported being mistreated as kids appear to have an elevated inflammatory response to stress compared to adults who had happier childhoods. Lead author Linda Carpenter, associate professor of psychiatry and human behavior, said that ...

A group of agricultural scientists reported in today's issue of the journal Science that corn that has been genetically engineered to produce insect-killing proteins isolated from the soil bacterium Bacillus thuringiensis (Bt) provides significant economic benefits even to neighboring farmers who grow non-transgenic varieties of corn. "Modern agricultural science is playing a critical role in addressing many of the toughest issues facing American agriculture today, including pest management and productivity," said Agriculture Secretary Tom Vilsack. "This study provides ...

London, UK (October, 07, 2010) –Many scientists aspire to take control over the stem cell differentiation process, so that we can grow organs and implants perfectly matched to each patient in the future. Now research in the Journal of Tissue Engineering, published by SAGE-Hindawi, explains how engineering the topography on which stem cells grow, and the mechanical forces working on them, can be as powerful an agent for change as their chemical environment. Stem cells respond to the stiffness, chemistry and topography of the environments they find themselves in – and scientists ...

WASHINGTON, DC-In the weeks leading up to the 2010 midterm elections, five forecasters or teams of forecasters offer models and predictions for the House in the most recent issue (October 2010) of PS: Political Science and Politics, a journal of the American Political Science Association. The models offer a broad consensus that the Republicans will make substantial gains in the House, although there is not a consensus over how large those gains will be. A 30-seat spread between the low and high end of the seat change forecast range exists, with two forecasters giving an ...

A team of researchers from North Carolina State University and the U.K. has found that the low rate of energy conversion in all-polymer solar-cell technology is caused by the structure of the solar cells themselves. They hope that their findings will lead to the creation of more efficient solar cells. Polymeric solar cells are made of thin layers of interpenetrating structures from two different conducting plastics and are increasingly popular because they are both potentially cheaper to make than those currently in use and can be "painted" or printed onto a variety ...

STANFORD, Calif. — A genetic marker touted as a predictor of coronary artery disease is no such thing, according to a study led by researchers at the Stanford University School of Medicine. The massive international study, published online Oct. 7 in the Journal of the American College of Cardiology, assessed the predictive value of a leading genetic assay for risk of atherosclerosis. The study analyzed the data from more than 17,000 patients with cardiovascular disease and 40,000 others to assess whether carrying a particular variant of the KIF6 gene indicated a greater ...

Researchers at the Institute for Genomic Biology at the University of Illinois have developed a way to harness the prodigious quantities of both genomic and metabolic data being generated with high-throughput genomics and other techniques. They have developed an algorithm that automatically integrates both data sets. The model, called probabilistic regulation of metabolism (PROM), enables researchers to perturb a given regulatory gene or metabolic process and see how that affects the entire network. "PROM provides a platform for studying the behavior of networks in a ...

Does thinking about time or money make you happier? A new study published in Psychological Science, a journal of the Association for Psychological Science, finds that people who are made to think about time plan to spend more of their time with the people in their lives while people who think about money fill their schedules with work, work, and—you guessed it—more work. To find out how thinking about time or money makes people feel, Cassie Mogilner of the University of Pennsylvania designed an experiment, carried out online with adults from all over the United States, ...

PROVIDENCE, R.I. [Brown University] — As the United States seeks to lessen its reliance on foreign oil, biodiesel is expected to play a role. According to the National Renewable Energy Laboratory, a branch of the Department of Energy, biodiesel "represents a significant energy resource and could someday supply 3 percent to 5 percent of the distillate fuel market." One major obstacle to achieving that goal is figuring how to efficiently convert the abundant stocks of waste vegetable oil (oil used after cooking French fries, for example) into biodiesel fuel. Current techniques ...

The way melanoma cells use the immune system to spread and develop into lung tumors may lead to a therapy to decrease development of these tumors, according to Penn State researchers. "Melanoma is the most aggressive and metastatic form of skin cancer," said Gavin Robertson, professor of pharmacology, pathology, dermatology and surgery in the Penn State College of Medicine. "Therefore, identifying proteins and molecular mechanisms that regulate metastasis is important for developing drugs to treat this disease." Metastasis is a complex process in which cancer cells ...

CAMBRIDGE, Mass. -- By creating a better way to see molecules at work in living brain cells, researchers affiliated with MIT's Picower Institute for Learning and Memory and the MIT Department of Chemistry are helping elucidate molecular mechanisms of synapse formation. These studies could also help further understanding of how synapses go awry in developmental diseases such as autism and Fragile X syndrome. The study will appear in the Oct. 7 issue of Cell. Using the new technique, which is more accurate and sensitive than existing methods, the researchers found that ...

WASHINGTON—October 7, 2010—The U.S. invested $139 billion last year in health research from all public and private sources, according to Research!America's latest annual estimate. That amount represents only 5.6% of the $2.47 trillion overall U.S. health spending in 2009—or 5.6¢ of every health dollar—which varies no more than 0.2% from 2005 levels. The estimate is available here: http://www.researchamerica.org/uploads/healthdollar09.pdf. The 2009 investment grew by only 0.1% over 2008. This small increase can be attributed largely to the federal stimulus funding ...

NASA satellites have collected data as the Atlantic Ocean's Tropical Depression 17 has undergone two changes in less than 24 hours. Since Oct. 6, the depression has strengthened and has tropical storm-force winds and has morphed from a sub-tropical storm into a tropical storm. After a United States Air Force Reserve reconnaissance flight subtropical depression seventeen was upgraded by the National Hurricane Center (NHC) to subtropical storm Otto on Oct. 6 at 5 p.m. EDT (2100 UTC). On Oct. 6 and 7, NASA's TRMM and Aqua satellites were flying overhead measuring very cold, ...

Saturn's icy moon Enceladus should not be one of the most promising places in our solar system to look for extraterrestrial life. Instead, it should have frozen solid billions of years ago. Located in the frigid outer solar system, it's too far from the sun to have oceans of liquid water -- a necessary ingredient for known forms of life -- on its surface. Some worlds, like Mars or Jupiter's moon Europa, give hints that they might harbor liquid water beneath their surfaces. Mars is about 4,200 miles across and Europa almost 2,000 miles across. However, with a diameter ...

PHILADELPHIA - Heart muscle cells do not normally replicate in adult tissue, but multiply with abandoned during development. This is why the loss of heart muscle after a heart attack is so dire—you can't grow enough new heart muscle to make up for the loss. A team of researchers at the University of Pennsylvania School of Medicine describe the interconnections between three-molecules that control fetal, heart-muscle-cell proliferation in a mouse model that will help cardiologists better understand the natural repair process after heart attacks and help scientists learn ...

CHAMPAIGN, Ill. — University of Illinois chemistry professor Alexander Scheeline wants to see high school students using their cell phones in class. Not for texting or surfing the Web, but as an analytical chemistry instrument. Scheeline developed a method using a few basic, inexpensive supplies and a digital camera to build a spectrometer, an important basic chemistry instrument. Spectrophotometry is one of the most widely used means for identifying and quantifying materials in both physical and biological sciences. "If we want to measure the amount of protein in ...

An approach pioneered by researchers at North Carolina State University gives scientists new insight into the way silicon bonds with other materials at the atomic level. This technique could lead to improved understanding of and control over bond formation at the atomic level, and opportunities for the creation of new devices and more efficient microchips. Manufacturers build silicon-based devices from layers of different materials. Bonds – the chemical interaction between adjacent atoms – are what give materials their distinctive characteristics. "Essentially, a bond ...

New Haven, Conn.—A team of Yale University scientists has engineered the cell wall of the Staphylococcus aureus bacteria, tricking it into incorporating foreign small molecules and embedding them within the cell wall. The finding, described online in the journal ACS Chemical Biology this week, represents the first time scientists have engineered the cell wall of a pathogenic "Gram-positive" bacteria—organisms responsible not only for Staph infections but also pneumonia, strep throat and many others. The discovery could pave the way for new methods of combating the bacteria ...

WEST LAFAYETTE, Ind. - A study by researchers at Purdue University suggests that some high school football players suffer undiagnosed changes in brain function and continue playing even though they are impaired. "Our key finding is a previously undiscovered category of cognitive impairment," said Thomas Talavage, an expert in functional neuroimaging who is an associate professor of biomedical engineering and electrical and computer engineering and co-director of the Purdue MRI Facility. The findings represent a dilemma because they suggest athletes may suffer a form ...

(Garrison, NY) The researcher whose revelations about unethical U.S. studies on syphilis in Guatemala in the 1940's led to apologies from the Obama administration last week has written a commentary for Bioethics Forum, the Hastings Center's online publication. She calls for the need to learn from history to better protect human subjects in the developing world. Susan M. Reverby, a professor at Wellesley College, describes how she unearthed documents about the study by accident while doing research for a book on the Tuskegee syphilis study. The documents, hidden in the ...