Too much TV, video and computer can make teens fatter
2010-09-20
Too much television, video games and Internet can increase body fat in teens. A five-year study from the University of Montreal and the Sainte-Justine Hospital Research Center, published in the American Journal of Epidemiology, has found teenagers have four different patterns of screen use: increasers, decreasers, consistently high and consistently low users.
Even teens from the consistently low group exceeded two hours per day of screen time on average, yet organizations such as the American Academy of Pediatrics and the Canadian Paediatric Society recommend limiting ...
Elderly might not benefit from TB vaccines in development
2010-09-20
COLUMBUS, Ohio – Elderly people might not benefit from some of the tuberculosis vaccines currently in development, recent research suggests.
Some vaccines under study are designed to activate a specific molecule that is an early participant in the immune response against TB in young people. But a recent Ohio State University study suggests that in older people, this molecule remains relatively inactive, even in the face of TB infection.
The animal research suggests that the presence of this molecule, called a toll-like receptor, is not required in an old mouse to generate ...
Nano antenna concentrates light
2010-09-20
HOUSTON – (Sept. 20, 2010) – Everybody who's ever used a TV, radio or cell phone knows what an antenna does: It captures the aerial signals that make those devices practical. A lab at Rice University has built an antenna that captures light in the same way, at a small scale that has big potential.
Condensed matter physicist Doug Natelson and graduate student Dan Ward have found a way to make an optical antenna from two gold tips separated by a nanoscale gap that gathers light from a laser. The tips "grab the light and concentrate it down into a tiny space," Natelson said, ...
Nanocatalyst is a gas
2010-09-20
HOUSTON – (Sept. 20, 2010) – A nanoparticle-based catalyst developed at Rice University may give that tiger in your tank a little more roar.
A new paper in the Journal of the American Chemical Society details a process by Rice Professor Michael Wong and his colleagues that should help oil refineries make the process of manufacturing gasoline more efficient and better for the environment.
In addition, Wong said, it could produce higher-octane gasoline and save money for an industry in which a penny here and a penny there add millions to the bottom line.
Wong's team ...
Pollution takes its toll on the heart
2010-09-20
MANHASSET, NY – The fine particles of pollution that hang in the air can increase the risk for sudden cardiac arrest, according to a new study conducted by a team from Long Island Jewish (LIJ) Medical Center and The Feinstein Institute for Medical Research.
Robert A. Silverman, MD, and his colleagues have been interested in the effects of ambient fine particulate matter on a number of medical conditions, including cardiovascular disease and asthma. The US Environmental Protection Agency (EPA) keeps tabs on air pollution through dozens of strategically placed pollution ...
Psychological pain of Holocaust still haunts survivors
2010-09-20
WASHINGTON – Holocaust survivors show remarkable resilience in their day-to-day lives, but they still manifest the pain of their traumatic past in the form of various psychiatric symptoms, according to an analysis of 44 years of global psychological research.
Jewish Holocaust survivors living in Israel also have higher psychological well-being than those who live in other countries, which suggests living in that country could serve as a protective factor, according to researchers in Israel and the Netherlands. Their findings are reported in Psychological Bulletin, which ...
How safe is your swipe?
2010-09-20
Used in a variety of products from credit cards to satellite televisions, secure chips are designed to keep encoded data safe. But hackers continue to develop methods to crack the chips' security codes and access the information within.
Thinking like hackers, Prof. Avishai Wool and his Ph.D. student Yossi Oren of Tel Aviv University's School of Electrical Engineering have developed an innovative way of extracting information from chip technology. By combining modern cryptology methods with constraint programming -- an area of computer science designed to solve a series ...
Climate change: Can geoengineering satisfy everyone?
2010-09-20
Reflecting sunlight from the Earth by geoengineering would undoubtedly cool the climate, but would different countries agree on how much to reflect? Research by climate scientists at the University of Bristol shows that the impact of geoengineering would be felt in very different ways across the world.
Previous studies of geoengineering approaches, aimed at averting dangerous climate change, have shown that although the average global temperature could be restored to 'normal' levels, some regions would remain too warm, whereas others would 'overshoot' and cool to much. ...
Pitt/Iowa team finds cellular structural molecule can be toxic: Makes pneumonia worse
2010-09-20
PITTSBURGH, Sept. 20 – A structural molecule and the cellular pump that regulates its levels influence the severity of pneumonia and could provide new ways of treating the lung infection, which is a leading cause of hospitalization and death, according to scientists at the University of Pittsburgh and the University of Iowa. Their findings are available online in Nature Medicine.
Despite decades of research, there has been little new information on what biological mechanisms make bacterial pneumonia get worse, said senior author Rama K. Mallampalli, M.D., a professor ...
Benefits of increased health care transparency hinge on reliable and valid information, says ACP
2010-09-20
(Washington) In a policy paper released today the American College of Physicians reaffirmed its support for increased health care transparency. Healthcare Transparency—Focus on Price and Clinical Performance Information, the first paper in a series of policy papers about transparency, is an introduction and overview of the issues and challenges faced with increased health care transparency.
"We believe that increasing transparency in the health care system can be beneficial to both patients and physicians," said J. Fred Raslton, Jr., MD, FACP, president of ACP. "However, ...
Compound boosts marijuana-like chemical in the body to relieve pain at injury site
2010-09-20
Irvine, Calif., Sept. 20, 2010 — American and Italian researchers have found that a novel drug allows anandamide – a marijuana-like chemical in the body – to effectively control pain at the site of an injury.
Led by Daniele Piomelli, the Louise Turner Arnold Chair in Neurosciences and director of the Center for Drug Discovery at UC Irvine, the study suggests that such compounds could form the basis of pain medications that don't produce sedation, addiction or other central nervous system side effects common with existing painkillers, such as opiates.
"These findings ...
Scientists show Six3 gene essential for retinal development
2010-09-20
New research led by St. Jude Children's Research Hospital investigators adds to evidence that the Six3 gene functions like a doorman in the developing brain and visual system, safeguarding the future retina by keeping the region where the eye is forming free of a signaling protein capable of disrupting the process.
The findings underscore the pivotal role Six3 plays in the developing nervous system as a key regulator of the Wnt family of signaling proteins and expands on earlier work from the laboratory of Guillermo Oliver, Ph.D., member of the St. Jude Department of ...
Millions with voice problems don't know treatment available
2010-09-20
DURHAM, N.C.—Two-thirds of Americans with voice problems don't seek medical care either because they don't know treatment is available or because they think the problem will just go away, according to a new study conducted at the Duke Voice Care Center.
That's concerning, says Seth Cohen, MD, an otolaryngologist at Duke. "Voice disorders aren't benign nuisances that just go away. They are symptoms of a range of medical conditions from allergies to cancer. When caught early, the right treatment can make a big difference. Left untreated, they can become chronic problems ...
New pathway regulates immune balance and offers promising drug development target
2010-09-20
St. Jude Children's Research Hospital scientists have identified a new pathway that helps control the immune balance through reciprocal regulation of specialized T lymphocytes, which play very different inflammatory roles.
Investigators also determined that two drugs working in different ways to dampen the inflammatory response in patients with multiple sclerosis or following organ transplantation target this new mechanism. Further research into the pathway might lead to new medications to block other autoimmune disorders or to new anti-rejection drugs, researchers said. ...
USC lab releases smartphone app that measures particulate air pollution
2010-09-20
University of Southern California computer scientists have found a way to combine smartphone resources with a novel application that allows the phones' users to help monitor air quality.
The application, provisionally titled "Visibility," is available for download at http://robotics.usc.edu/~mobilesensing/Projects/AirVisibilityMonitoring
The researchers, from the USC Viterbi School of Engineering, hope that as many users as possible download and try it in order to improve the software. Currently, the download works for smartphones running the Android system and soon ...
Mayo-led researchers discover genetic variants modifying breast cancer risk
2010-09-20
ROCHESTER, Minn. -- Individuals with disrupting mutations in the BRCA1 gene are known to be at substantially increased risk of breast cancer throughout their lives. Now, discoveries from an international research team led by Mayo Clinic researchers show that some of those persons may possess additional genetic variants that modify their risk. These new findings enhancing individualized medicine appear in the current Nature Genetics.
"These findings should be useful in helping determine individual risk for breast cancer in BRCA1 carriers," says Fergus Couch, Ph.D., Mayo ...
4 possible risk factors for ovarian cancer found
2010-09-20
ROCHESTER, Minn. -- A consortium of cancer researchers has identified four chromosome locations with genetic changes that are likely to alter a woman's risk of developing ovarian cancer. The findings appear in Nature Genetics in an article authored by a Mayo Clinic researcher.
Researchers say that while more needs to be learned about the function of the specific chromosomal regions involved in susceptibility, the discoveries move them a major step closer to individualized risk assessments for ovarian cancer. In the future, women at greatest risk due to these and other ...
Technology in the extreme
2010-09-20
Radio transmitters that can withstand temperatures of up to 900 oC could soon be dropped into the depths of the earth to provide early warning of a volcanic eruption.
The state-of-the-art technology being pioneered by experts at Newcastle University uses Silicon Carbide electronics that can withstand temperatures equal to the inside of a jet engine.
Measuring subtle changes in the levels of key volcanic gases such as carbon dioxide and sulphur dioxide, the wireless sensor would feed back real-time data to the surface, providing vital information about volcanic activity ...
2 studies find new genetic links to ovarian cancer risk
2010-09-20
DURHAM, N.C. – An international consortium of scientists has discovered new genetic variants in five regions of the genome that affect the risk of ovarian cancer in the general population, according to two separate studies published today (Sunday), online in Nature Genetics.
The consortium, including scientists from the U.S., Europe, Canada and Australia, based the new work on their earlier research comparing 10,283 women with ovarian cancer to 13,185 women without the disease. That effort had found a stretch of DNA on chromosome 9 containing single DNA letter variations ...
Possible alternate therapy for adults with poorly controlled asthma
2010-09-20
A drug commonly used for the treatment of chronic obstructive pulmonary disease (COPD) successfully treats adults whose asthma is not well-controlled on low doses of inhaled corticosteroids, reported researchers supported by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health.
"This study's results show that tiotropium bromide might provide an alternative to other asthma treatments, expanding options available to patients for controlling their asthma," said NHLBI Acting Director Susan B. Shurin, M.D. "The goal in managing ...
Biologists discover biochemical link between biological clock and diabetes
2010-09-20
Biologists have found that a key protein that regulates the biological clocks of mammals also regulates glucose production in the liver and that altering the levels of this protein can improve the health of diabetic mice.
Their discovery, detailed in this week's advanced online publication of the journal Nature Medicine, provides an entirely new biochemical approach for scientists to develop treatments for obesity and type 2 diabetes. It also raises the interesting possibility that some of the rise in diabetes in the U.S. and other major industrialized countries could ...
Rutgers researchers discover how HIV resists AZT
2010-09-20
NEW BRUNSWICK, N.J. – Rutgers researchers have discovered how HIV-1, the virus that causes AIDS, resists AZT, a drug widely used to treat AIDS.
The scientists, who report their findings in Nature Structural & Molecular Biology, believe their discovery helps researchers understand how important anti-AIDS treatments can fail and could help AIDS researchers develop more effective treatment for the disease.
"What we've found is the detailed way in which the mutations act to promote the resistance," said author Eddy Arnold, Board of Governors Professor of Chemistry and ...
Childhood viral infection may be a cause of obesity
2010-09-20
The emerging idea that obesity may have an infectious origin gets new support in a cross-sectional study by University of California, San Diego School of Medicine researchers who found that children exposed to a particular strain of adenovirus were significantly more likely to be obese.
The study will be published in the September 20 online edition of the journal Pediatrics. September is National Childhood Obesity Awareness Month.
Jeffrey B. Schwimmer, MD, associate professor of clinical pediatrics at UC San Diego, and colleagues examined 124 children, ages 8 to 18, ...
Manganese in drinking water: Study suggests adverse effects on children's intellectual abilities
2010-09-20
A team of researchers led by Maryse Bouchard, adjunct professor at the Center for Interdisciplinary Research in Biology, Health, Environment and Society (CINBIOSE) of the Université du Québec à Montréal and a researcher at Sainte-Justine University Hospital, and Donna Mergler, professor emerita in the Department of Biological Sciences and a member of CINBIOSE, recently completed a study showing that children exposed to high concentrations of manganese in drinking water performed worse on tests of intellectual functioning than children with lower exposures. Their results ...
Higher incidence of seizures seen in children with H1N1 virus compared to seasonal flu
2010-09-20
A recent study by researchers at the University of Utah determined that the 2009 pandemic influenza A (H1N1) caused a higher rate of neurological complications in children than the seasonal flu. The most common complications observed were seizures and encephalopathy. Full details of the study, the most extensive evaluation of neurological complications following H1N1 flu in children, are published in the September issue of Annals of Neurology, a journal of the American Neurological Association.
The H1N1 virus (swine flu) was identified in Mexico and the U.S. in April ...
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