Sharply focused on neurons, light controls a worm's behavior
CAMBRIDGE, Mass., Jan. 18, 2011 -- Physicists and bioengineers have developed an optical instrument allowing them to control the behavior of a worm just by shining a tightly focused beam of light at individual neurons inside the organism.
The pioneering optogenetic research, by a team at Harvard University, the University of Pennsylvania, and the University of Massachusetts Medical School, is described this week in the journal Nature Methods. Their device is known as the CoLBeRT (Controlling Locomotion and Behavior in Real Time) system for optical control of freely moving ...




