Fatty acid composition in blood reflects the quality of dietary carbohydrates in children

(Press-News.org) Recently published research in the University of Eastern Finland found that fatty acid composition in blood is not only a biomarker for the quality of dietary fat but also reflects the quality of dietary carbohydrates. For example the proportion of oleic acid was higher among children who consumed a lot of candy and little high-fibre grain products. Earlier studies on the topic have mainly concentrated on the association of the quality of dietary fat with fatty acid composition in blood. In the present study, the association of the quality of dietary carbohydrates with plasma fatty acid composition was investigated for the first time in children. A higher consumption of candy and a lower consumption of high-fibre grain products were associated with a higher proportion of oleic acid in blood. One explanation for this finding may be that children who consumed more candy and less high-fibre grain products also consumed more foods rich in saturated fat. Saturated fat, that is known to be harmful to health, has previously been shown to correlate positively with oleic acid intake in Western diet not favoring olive oil. A higher consumption of candy was associated with a higher estimated delta-9 desaturase that indicates the activity of delta-9-desaturase in liver. A higher intake of carbohydrates has previously been shown to be associated with a higher activity of delta-9-desaturase in adults but the studies on this topic are lacking in children. The delta-9-desaturase is an enzyme that catalyzes the reactions of producing monounsaturated fatty acids from saturated fatty acids. Thus, it prevents the accumulation of saturated fatty acids in the liver but at the same time it promotes the excretion of fatty acids to the blood stream. The increase in delta-9-desaturase activity may be related to an increased production of saturated fatty acids from sugar in the liver that is harmful for lipid metabolism. A higher consumption of vegetable oil-based margarine containing at least 60 percent fat was associated with higher proportions of polyunsaturated fatty acids, linoleic acid and alfa-linolenic fatty acid in blood that is in line with the results of the previous studies in adults and children. A higher consumption of vegetable oil-based margarine was also associated with lower proportions of saturated fatty acids and monounsaturated fatty acids known to be advantageous to health. The Physical Activity and Nutrition in Children Study investigates health of children in Kuopio The present study was conducted in the University of Eastern Finland and it was based on the Physical Activity and Nutrition in Children (PANIC) Study. The PANIC Study is an ongoing exercise and diet intervention study in a population sample of 512 children 6-8 years of age from the city of Kuopio. The consumption of foods was assessed by 4-day food records and the fatty acid composition in blood was assessed by gas chromatograph from a fasting blood sample.

The results of the present study were published in Lipids.

INFORMATION: For further information, please contact: M.Sc. Taisa Venäläinen, tel. 040 9635721, taisa.venalainen@uef.fi Professor Timo Lakka, tel. 040 7707329, timo.lakka@uef.fi

Taisa Venäläinen, Ursula Schwab, Jyrki Ågren, Vanessa de Mello, Virpi Lindi, Aino-Maija Eloranta, Sanna Kiiskinen, David Laaksonen,Timo A. Lakka. Cross-Sectional Associations of Food Consumption with Plasma Fatty Acid Composition and Estimated Desaturase Activities in Finnish Children. Lipids March 14. DOI 10.1007/s11745-014-3894-7.