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Prenatal exposure to THC, CBD affects offspring's responsiveness to fluoxetine

2021-07-01
(Press-News.org) BLOOMINGTON, Ind. -- Scientists at Indiana University have found that significant amounts of the two main components of cannabis, THC and CBD, enter the embryonic brain of mice in utero and impair the mice's ability as adults to respond to fluoxetine, a drug commonly used to treat anxiety and depression and known by the brand name Prozac.

The study suggests that when the developing brain is exposed to THC or CBD, normal interactions between endocannabinoid and serotonin signaling may be diminished as they become adults.

"Hemp-derived CBD is a legal substance in the U.S., and we are in a time of increasing state-level legalization of cannabis. Therefore, use of cannabis components have increased across most levels of society, including among pregnant women," said END


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[Press-News.org] Prenatal exposure to THC, CBD affects offspring's responsiveness to fluoxetine