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Perfecting collagen production in osteogenesis imperfecta

By studying the controversial idea that hematopoietic stem cells could give rise to osteoblasts, researchers at MUSC Health aim to address the root cause of brittle bone disease

Perfecting collagen production in osteogenesis imperfecta
2021-07-22
(Press-News.org) Most people can expect to break close to two bones in their lifetime, but those with osteogenesis imperfecta -- also known as brittle bone disease -- can break hundreds of bones before they even hit puberty. And while healthy bones can break from a hard fall or a bad car wreck, there may not be an apparent reason at all with brittle bone disease.

Classified as a rare disease, osteogenesis imperfecta, or OI, affects 6-7 people out of every 100,000 live births and can range in severity depending on the specific mutation. And while there are currently few treatment options and no cure, Meenal Mehrotra, M.D., Ph.D., and her lab recently published END

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Perfecting collagen production in osteogenesis imperfecta

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[Press-News.org] Perfecting collagen production in osteogenesis imperfecta
By studying the controversial idea that hematopoietic stem cells could give rise to osteoblasts, researchers at MUSC Health aim to address the root cause of brittle bone disease