Paris is set to host the highly anticipated 25th International Conference of the Redox Medicine Society, where global leaders and experts from the field will converge to unveil groundbreaking advancements and shed light on the future of Redox Medicine. Taking place from June 21 to June 23, the conference will feature over 61 dynamic communications, including major presentations, short talks, and poster sessions, showcasing the latest research and discoveries in the field of redox reactions, oxidative stress, and their profound impact on health and disease.
What we mean by Redox Medicine?
Redox medicine is a wide impact in field that explores how the balance of oxidation and reduction—collectively known as "redox" reactions—impacts health and disease. It's closely linked to the study of antioxidants, oxidative stress, and the role of free radicals impact.
Redox reactions are essential for various biochemical processes, such as proliferation and energy production in cells, immune responses, and detoxification processes. When the balance of the redox status is disturbed, it can lead to harmful conditions known as oxidative stress, which is implicated in numerous diseases, including neurodegenerative diseases, cardiovascular disease, cancer, diabetes, immune related pathologies and even the process of aging.
Redox medicine, therefore, aims to use strategies to prevent, diagnose, and treat by targeting redox processes.
Different axis of Redox Medicine
The current promising data based on new targets, drugs and drug repurposing are mainly the result of academic efforts. With the availability of optimized compounds and coordinated efforts between academic and industrial scientists, clear validation and translation into proof-of-concept studies seems achievable in the near future, potentially leading to a new era of redox medicine in the following main axis:
Precision Medicine: By understanding how redox reactions affect individual patients, treatments could be tailored more specifically to each person's unique biochemical makeup, which is the goal of precision medicine.
Preventive Medicine: Biomarkers that signal redox imbalances could be used to catch diseases earlier, before symptoms develop, making prevention a more attainable goal.
Treatment of Chronic Diseases: Many chronic diseases, such as auto-immune diseases that impact 10% of the industrialized population have been linked to oxidative stress. Redox medicine could lead to more effective treatments or even cures for these widespread conditions.
Healthy Aging: Oxidative stress is implicated in the aging processes. Redox medicine can help to promote healthier aging, reducing age-related diseases. Redox medicine might also contribute to our understanding of the aging process and potentially to interventions aimed at promoting healthy aging and longevity.
Integration with Digital Health and Artificial intelligence: Redox balance and oxidative stress markers need to be monitored continuously through wearable devices, providing real-time feedback to individuals and healthcare providers.
All of these axis will be discussed during Redox Medicine 2023.
Speakers and topics for the Redox Medicine conference in 2023
Keynote Speaker:
Guido Kroemer, Université de Paris Cité, Hôpital Européen George Pompidou, France Topic: "Hallmarks of Aging & Redox Medicine: An Expanding Universe"
Concluding Remarks:
Chandan K. Sen, Editor in Chief of ARS, Indiana University, USA Topic: "Redox Medicine 2023: What's Next?"
Workshop:
Ginette Deby-Dupont, Liège University, Belgium Topic: "From Antioxidants to Redox Medicine: How to Evaluate Oxidative Stress and Protect Redox Homeostasis?"
Speakers and Topics:
Martin Feelisch, University of Southampton, United Kingdom Topic: "Redox Medicine in the Anthropocene – How do we make it work?"
Marcus Conrad, Helmholtz Zentrum München, Germany Topic: "Ferroptosis: A Decade Before and After the Coining"
Raphael Rodriguez, Institut Curie, France Topic: "Ferroptosis 2023: New Insights & Discoveries"
Carole Nicco, President of Redox Medicine Society, Institut Cochin - INSERM U1016, Université de Paris, France Topic: "Arsenic-Copper: A Double-Edged Sword for a Unique Double Benefit against Immunological Disorders"
Charareh Pourzand, University of Bath, United Kingdom Topic: "The Determination of Intracellular Labile Ironome for Diagnosis and Prognosis of Iron-Related Disorders: the Example of Friedreich's Ataxia"
Benoit D'Autréaux, Paris-Saclay University, France Topic: "Friedreich's ataxia: the pathological iron-redox axis revisited"
Amalia M. Dolga, University of Groningen, The Netherlands Topic: "Redox Medicine, Mitochondria & Aging: The Underestimated Link"
Nikolas Gunkel, Deutsches Krebsforschungszentrum, Germany Topic: "Antioxidant Capacity Biomarkers, a Path Forward to Develop ROS-Inducing Drugs for Cancer Therapy"
Francesco Bellanti, University of Foggia, Italy Topic: "Redox Homeostasis and Sarcopenia: Targeting Mitochondria"
Wee Han Ang, National University of Singapore, Singapore Topic: "Antibacterial Strategies Based on Reactive Oxygen Species"
Laurent Chatre, Normandie University, UNICAEN Cyceron, Centre national de la recherche scientifique (CNRS), France Topic: "Chronobiology: The Reactive Species Interactome-Mitochondria Axis, the Hands of the Circadian Clock?"
Chang Chen, Institute of Biophysics, Chinese Academy of Sciences Topic: "Precision Redox: The Key for Antioxidant Pharmacology"
Jérôme Santolini, Laboratoire Stress Oxydant et Détoxication, France Topic: "A Redox Theory of Biological Regulation"
Morgane Locker, Université Paris-Saclay, France. Topic :“Awakening Adult Retinal Stem Cells: A New Function of NOX Signaling in the Xenopus Retina”
Melanie Merkel, Philipps-Universität Marburg, Germany. Topic: Mitochondrial Involvement in Different Model Systems of Ferroptosis”
Dong-Yun Shi, Fudan University, China. Topic: “Redox Balance as a Biomarker: Towards Personalized Interventions for Health:
Moran Benhar, Technion University, Israel. Topic: “Effects of Reactive Sulfur Species in Macrophage Activation and Regulation of Apoptosis/Necrosis Pathways in Cancer Cells”
Robert A Heaton, University of Liverpool, United Kingdom. Topic: “Redox Medicine & Signaling: Molecular Mechanisms Underlying Age-Related Muscle Decline”
Mauricio S. Baptista, Universidade de São Paulo, Brazil. Topic: “The Skin Redoxome: Perspectives in Photodamage and Sun Care”
Access the full conference agenda.
Supporter and Contributing Partner of Redox Medicine 2023
Agilent (supporter), that will be showcasing their innovations, devices, and strategies to evaluate redox.
Antioxidants & Redox Signaling Journal (contributing partner), in which all the conference proceedings will be published (indexed in Medline and of impact factor 7.468).
More about Redox Medicine Society (RSM or formerly ISANH):
ISANH was established 25 years ago to discuss research on free radicals and their implications in various human pathologies. During the Paris Redox 2022 Conference, the Scientific Committee discussed how to transform ISANH, how to face new challenges and how to redesign the strategies as it is now time to update its aims and targets.
Today, the Redox Medicine field's importance is further increasing with new knowledge in redox biochemistry, translational strategies could lead to new innovative diagnostic and preventive tools as well as therapeutic approaches in life sciences and medicine. Our efforts aim to facilitate the translation of basic knowledge of redox biology into molecular medicine and to discover innovative new approaches to prevention, diagnosis and treatment.
END
