(Press-News.org) Virginia Tech researchers with the Fralin Biomedical Research Institute at VTC have demonstrated that children with a wide range of diagnoses that affect their motor function improve after receiving intensive pediatric neurorehabilitation called ACQUIRE Therapy.
The findings were published in June in Behavioral Sciences and will be included in an upcoming special issue of the journal devoted to “shifting the therapeutic paradigm for children with neuromotor disabilities to maximize development.”
“We present a great deal of clinical data, and also describe a framework for intensive therapy that we have developed over the last 20 years,” said Stephanie DeLuca, associate professor of the Fralin Biomedical Research Institute. “Our research highlights the need for standardized methodologies and training for therapists to maximize the effectiveness of intensive therapies.”
The study was authored by Mary Rebekah Trucks and Dory Wallace, both associate directors and therapists at the Fralin Biomedical Research Institute Neuromotor Research Clinic, and clinic co-directors DeLuca and Sharon Landesman Ramey.
The ACQUIRE Therapy was originally developed two decades ago by DeLuca and Landesman Ramey, along with Karen Echols a colleague at the University of Alabama at Birmingham as a form of Constraint-Induced Movement therapy (CIMT).
Since then DeLuca, Trucks, Wallace, and Landesman Ramey have worked together to further develop the ACQUIRE Framework and Therapy Model to become much broader than CIMT.
“The actual moment-by-moment teaching, and the importance of therapists having a dynamic awareness of the environment and knowing how to take advantage of it, are extremely important,” said Landesman Ramey, research professor and distinguished research scholar of the Fralin Biomedical Research Institute.
“The science behind the ACQUIRE form of high-intensity training often focuses on the high dosages – the number of hours in therapy every day for several weeks,” said Landesman Ramey, who also is a faculty member of the Department of Psychology of the Virginia Tech College of Science. “That is important, but there is much more to it than that.”
The new paper includes outcomes from ACQUIRE Therapy provided to children aged 7 months to 20 years with various motor impairments, including hemiparesis and quadriparesis, which describe different degrees of weakness or partial paralysis in the body.
The study findings reveal functional improvements across a wide range of diagnostic categories, including cerebral palsy, stroke, traumatic brain injury, arteriovenous malformation, hemispherectomy, and others.
Because clinical populations are highly diverse, therapy often requires tailored approaches to be effective.
“The ACQUIRE therapy framework and overall model of therapy provides therapists some decision-making guidelines that can be used across diagnoses and differing types of motor impairments” said DeLuca, who is also affiliated with the School of Neuroscience of the Virginia Tech College of Science. “It also provides a platform for providing therapists additional training for implementing these intensive therapeutic approaches effectively.”
Looking ahead, the study calls for further standardization of methodologies and decision-making processes in the delivery of intensive therapies to ensure consistent and effective outcomes.
By translating research findings into practice and investing in therapist training, the field of pediatric neurorehabilitation can continue to advance and provide high-quality intensive therapies to children with motor impairments due to brain injuries or disorders, the authors say.
END
ACQUIRE therapy framework shows results for intensive pediatric rehabilitation
Fralin Biomedical Research Institute study shows effective therapeutic interactions, improved outcomes for children with motor disabilities caused by brain injuries or disorders
2023-06-16
ELSE PRESS RELEASES FROM THIS DATE:
New research shows HIV can lie dormant in the brain
2023-06-16
As a part of its life cycle, the human immunodeficiency virus-1 (HIV) inserts a copy of its DNA into human immune cells. Some of these newly infected immune cells can then transition into a dormant, latent state for a long period of time, which is referred to as HIV latency.
Although current therapies, such current antiretroviral therapy (ART), can successfully block the virus from replicating further, it cannot eradicate latent HIV. If treatment is ever discontinued, the virus can rebound from latency and reignite the progression of HIV infection to AIDS.
Scientists from the HIV Cure Center at the UNC School of Medicine, University of California ...
For resistant breast cancers, two drugs may be better than one
2023-06-16
Cancer cells are even smarter than scientists previously believed, according to new CU Boulder research. When these cells are confronted with potent new drugs called CDK2 inhibitors, which are designed to prevent cancer from proliferating, they can trigger a workaround to survive the assault in as little as one to two hours.
But the study, published June 8 in the journal “Cell,” comes with a silver lining.
It reveals how cancer cells complete this adaption and shows that simultaneously administering a second, already widely ...
UMass Amherst biostatistician developing statistical tools to predict breast cancer survival and inform targeted therapies
2023-06-16
Breast cancer is a complex disease, and its progression is difficult, yet important, to predict.
While many elements may contribute to a breast cancer prognosis, University of Massachusetts Amherst biostatistician Chi Hyun Lee has zeroed in on one risk factor that has emerged for its potential to predict the disease’s progression.
Lee will use a two-year, $154,791 grant from the National Institutes of Health (NIH) in an effort to develop statistical tools that will better predict breast cancer survival rates and survival time after breast cancer recurrence.
While the project focuses on breast cancer research, the proposed statistical ...
Jefferson Lab outreach efforts earn national recognition
2023-06-16
NEWPORT NEWS, VA – When the global pandemic put the kibosh on in-person events, the U.S. Department of Energy’s Thomas Jefferson National Accelerator Facility sought alternatives for ensuring its world-class science and unique equipment remained accessible. These efforts culminated in the Fall for Science Virtual Field Trip Event, which rolled out a virtual tour experience, new website, and unique supporting materials. Now, the event has been recognized by the Public Relations Society of America with three Anvil Awards.
According ...
Uncovering a cellular process that leads to inflammation
2023-06-16
Cedars-Sinai investigators have identified several steps in a cellular process responsible for triggering one of the body’s important inflammatory responses. Their findings, published in the peer-reviewed journal Science Immunology, open up possibilities for modulating the type of inflammation associated with several infections and inflammatory diseases.
Specifically, the investigators have improved understanding of the steps that lead to the production of IL-1 beta, a potent inflammatory protein signal released during many inflammatory responses.
“We now have a clearer understanding of the stepwise process that leads to the production of IL-1 beta,” said Andrea ...
New imaging technique is no last resort
2023-06-16
There are various ways to image biological samples on a microscopic level, and each has its own pros and cons. For the first time, a team of researchers, including those from the University of Tokyo, has combined aspects from two of the leading imaging techniques to craft a new method of imaging and analyzing biological samples. Its concept, known as RESORT, paves the way to observe living systems in unprecedented detail.
For as long as humanity has been able to manipulate glass, we have used optical devices to peer at the microscopic world in ever increasing ...
Abnormalities in neurodevelopment could lay the foundations for Alzheimer’s disease
2023-06-16
In the cerebral cortex, neurogenesis – the formation of neural cells from stem cells – begins in the fetus from 5 weeks gestation and is almost complete by 28 weeks. It is a complex process with finely tuned mechanisms. “In humans, neurogenesis lasts particularly long compared with other species, explains Khadijeh Shabani, a post-doctoral researcher at Paris Brain Institute. Neural stem cells remain in a progenitor state for an extended period. Only later do they differentiate into glial cells, astrocytes, or oligodendrocytes that will form the architecture of the brain and spinal cord.”
Until ...
Disorient the malaria parasite to prevent it from causing harm
2023-06-16
With almost 250 million cases a year, 621,000 of them fatal, malaria remains a major public health problem, particularly in sub-Saharan Africa. Malaria is a parasitic disease transmitted by mosquitoes and caused by a microbe of the genus Plasmodium. On its journey from mosquito to human, Plasmodium must adapt to the specificities of the many organs and cells it parasitizes. Microbes do not have sensory organs; instead, they have sensors made of proteins to detect molecules specific to the environments they colonize. While most living organisms share the same types of sensors, Plasmodium is an exception. Biologists at the University of Geneva (UNIGE) have identified a new type ...
Growing number of hypothyroidism patients receiving treatment other than levothyroxine
2023-06-16
The use of thyroid hormones other than the commonly prescribed hormone medicine levothyroxine to treat hypothyroidism, or underactive thyroid, is increasing, according to a study being presented Friday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.
“This is significant because the long-term health outcomes of these treatments are not as well known as levothyroxine,” said researcher Matthew Ettleson, M.D., of the University of Chicago in Chicago, Ill.
The thyroid makes the hormones triiodothyronine ...
Prevalence of metabolic associated fatty liver disease is increasing
2023-06-16
CHICAGO—The percent of metabolic associated fatty liver disease (MAFLD), the leading global cause of liver disease, is increasing in U.S. adults, according to a study presented Friday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.
Mexican Americans consistently had the highest percentage of MAFLD, especially in 2018, although the prevalence of increase was higher among Whites, the study found.
MAFLD, previously known as non-alcoholic fatty liver disease (NAFLD), is fast becoming the most common indication ...
LAST 30 PRESS RELEASES:
Slow editing of protein blueprints leads to cell death
Industrial air pollution triggers ice formation in clouds, reducing cloud cover and boosting snowfall
Emerging alternatives to reduce animal testing show promise
Presenting Evo – a model for decoding and designing genetic sequences
Global plastic waste set to double by 2050, but new study offers blueprint for significant reductions
Industrial snow: Factories trigger local snowfall by freezing clouds
Backyard birds learn from their new neighbors when moving house
New study in Science finds that just four global policies could eliminate more than 90% of plastic waste and 30% of linked carbon emissions by 2050
Breakthrough in capturing 'hot' CO2 from industrial exhaust
New discovery enables gene therapy for muscular dystrophies, other disorders
Anti-anxiety and hallucination-like effects of psychedelics mediated by distinct neural circuits
How do microbiomes influence the study of life?
Plant roots change their growth pattern during ‘puberty’
Study outlines key role of national and EU policy to control emissions from German hydrogen economy
Beloved Disney classics convey an idealized image of fatherhood
Sensitive ceramics for soft robotics
Trends in hospitalizations and liver transplants associated with alcohol-induced liver disease
Spinal cord stimulation vs medical management for chronic back and leg pain
Engineered receptors help the immune system home in on cancer
How conflicting memories of sex and starvation compete to drive behavior
Scientists discover ‘entirely unanticipated’ role of protein netrin1 in spinal cord development
Novel SOURCE study examining development of early COPD in ages 30 to 55
NRL completes development of robotics capable of servicing satellites, enabling resilience for the U.S. space infrastructure
Clinical trial shows positive results for potential treatment to combat a challenging rare disease
New research shows relationship between heart shape and risk of cardiovascular disease
Increase in crisis coverage, but not the number of crisis news events
New study provides first evidence of African children with severe malaria experiencing partial resistance to world’s most powerful malaria drug
Texting abbreviations makes senders seem insincere, study finds
Living microbes discovered in Earth’s driest desert
Artemisinin partial resistance in Ugandan children with complicated malaria
[Press-News.org] ACQUIRE therapy framework shows results for intensive pediatric rehabilitationFralin Biomedical Research Institute study shows effective therapeutic interactions, improved outcomes for children with motor disabilities caused by brain injuries or disorders