Incidence of diabetes among youth before and during the pandemic

JAMA Network Open

2023-09-21

(Press-News.org) About The Study: In this study that included data from Kaiser Permanente Southern California of individuals age 19 and younger, the incidence of type 1 diabetes slightly increased overall and type 2 diabetes significantly increased after the beginning of the COVID-19 pandemic, in particular among non-Hispanic Black and Hispanic youth. These findings suggest the need for further evaluation of physiologic and behavioral risk factors preceding new-onset diabetes during the pandemic.

Authors: Matthew T. Mefford, Ph.D., of Kaiser Permanente Southern California in Pasadena, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2023.34953)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.34953?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=092123

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

Disparities in emergency medicine residents’ performance assessments by race, ethnicity, and sex

2023-09-21

About The Study: This analysis of assessments of 2,708 emergency medicine residents found evidence of sex-specific ethnoracial disparities in ratings on the Milestones assessments. These disparities increased over time across multiple Milestones assessments and were most severe for female residents of ethnoracial groups that are underrepresented in medicine. Authors: Elle Lett, Ph.D., M.A., M.Biostat., of the University of Washington School of Public Health in Seattle, is the corresponding author. To ...

New origin story for key regulatory gene

2023-09-21

Polycomb repressive complex 2 (PRC2) was discovered decades ago in Drosophila, where it was found to be a key controller of developmental genes. Further analyses showed that PRC2 modifies chromatin and silences target gene expression. However, the ancestral function of PRC2 - as functioning primarily to control genes during development - was called into question when researchers discovered that PRC2 also plays a role in unicellular species, in which no development takes place. A first hint at PRC2’s original role came from studies in red algae, which found PRC2 left its methylation mark on transposons – jumping genes that ...

Ultrathin films achieve record hydrogen-nitrogen separation

2023-09-21

Metal-organic frameworks (MOFs) are a class of materials that contain nano-sized pores. These pores give MOFs record-breaking internal surface areas, which make them extremely versatile for a number of applications: separating petrochemicals and gases, mimicking DNA, producing hydrogen, and removing heavy metals, fluoride anions, and even gold from water are just a few examples. In the gas-separation domain, MOFs are particularly interesting for separating hydrogen from nitrogen, which is crucial for clean energy production, fuel cell efficiency, ammonia synthesis, and various ...

Getting ready for bed controlled by specific brain wiring in mice

2023-09-21

The team, led by Imperial College London researchers, uncovered the wiring in mouse brains that leads them to begin nesting in preparation for sleep. Published today in Nature Neuroscience, the study reveals that preparing properly for sleep is likely a hard-wired survival feature – one often neglected or overridden by humans. We all need to sleep, but since we are unconscious when we do so, it makes sense to fall asleep in a safe and warm place. For some animals this is especially important, as a burrow or nest provides a haven from ...

Mutation-specific peptide vaccine against midline gliomas used in patients for the first time

2023-09-21

Tumor vaccines can help the body fight cancer. These vaccines alert the patient's immune system to proteins that are carrying cancer-typical alterations. Physicians and cancer researchers from Heidelberg and Mannheim have now treated adult patients with advanced midline gliomas, difficult-to-treat brain tumors, with a peptide vaccine for the first time. The vaccine mimicked a mutational change in a histone protein typical of this type of cancer. The vaccine proved to be safe and induced the desired immune responses directed ...

This parasitic plant convinces hosts to grow into its own flesh—it’s also an extreme example of genome shrinkage

2023-09-21

If you happen to come across plants of the Balanophoraceae family in a corner of a forest, you might easily mistake them for fungi growing around tree roots. Their mushroom-like structures are actually inflorescences, composed of minute flowers. But unlike some other parasitic plants that extend an haustorium into host tissue to steal nutrients, Balanophora induces the vascular system of their host plant to grow into a tuber, forming a unique underground organ with mixed host-parasite tissue. This ...

Mutations in 11 genes associated with aggressive prostate cancer identified in new research

2023-09-21

An international research team led by scientists in the Center for Genetic Epidemiology at the Keck School of Medicine of USC and USC Norris Comprehensive Cancer Center has singled out mutations in 11 genes that are associated with aggressive forms of prostate cancer. These findings come from the largest-scale prostate cancer study ever exploring the exome — that is, the key sections of the genetic code that contain the instructions to make proteins. The scientists analyzed samples from about 17,500 prostate cancer ...

Dinosaur feathers reveal traces of ancient proteins

2023-09-21

Palaeontologists at University College Cork (UCC) in Ireland have discovered X-ray evidence of proteins in fossil feathers that sheds new light on feather evolution. Previous studies suggested that ancient feathers had a different composition to the feathers of birds today. The new research, however, reveals that the protein composition of modern-day feathers was also present in the feathers of dinosaurs and early birds, confirming that the chemistry of feathers originated much earlier than previously thought. The research, published today in Nature Ecology and Evolution, was led by palaeontologists ...

Researchers develop first method to study microRNA activity in single cells

2023-09-21

MicroRNAs are small molecules that regulate gene activity by binding to and destroying RNAs produced by the genes. More than 60% of all human genes are estimated to be regulated by microRNAs, therefore it is not surprising that these small molecules are involved in many biological processes including diseases such as cancer. To discover the function of a microRNA, it is necessary to find out exactly which RNAs are targeted by it. While such methods exist, they require a lot of material typically in order of millions of cells, to ...

Nanoparticles made from plant viruses could be farmers’ new ally in pest control

2023-09-21

A new form of agricultural pest control could one day take root—one that treats crop infestations deep under the ground in a targeted manner with less pesticide. Engineers at the University of California San Diego have developed nanoparticles, fashioned from plant viruses, that can deliver pesticide molecules to soil depths that were previously unreachable. This advance could potentially help farmers effectively combat parasitic nematodes that plague the root zones of crops, all while minimizing costs, pesticide use and environmental toxicity. Controlling infestations caused by root-damaging nematodes has long been a challenge in agriculture. One reason is that the types of pesticides ...

LAST 30 PRESS RELEASES:

Label distribution similarity-based noise correction for crowdsourcing

The Lancet: Without immediate action nearly 260 million people in the USA predicted to have overweight or obesity by 2050

Standardized autism screening during pediatric well visits identified more, younger children with high likelihood for autism diagnosis

Researchers shed light on skin tone bias in breast cancer imaging

Study finds humidity diminishes daytime cooling gains in urban green spaces

Tennessee RiverLine secures $500,000 Appalachian Regional Commission Grant for river experience planning and design standards

New study in Science finds that just four global policies could eliminate more than 90% of plastic waste and 30% of linked carbon emissions by 2050

Breakthrough in capturing 'hot' CO2 from industrial exhaust

New discovery enables gene therapy for muscular dystrophies, other disorders

[Press-News.org] Incidence of diabetes among youth before and during the pandemic
JAMA Network Open