Prenatal lead exposure, genetic factors, and cognitive developmental delay

JAMA Network Open

2023-10-23

(Press-News.org) About The Study: In this study of 2,361 mother-child pairs followed up prenatally to child age of approximately two years, prenatal lead exposure was associated with an increased risk of cognitive developmental delay (CDD) in children, especially in those with a high genetic risk. These findings suggest that prenatal lead exposure and genetic background may jointly contribute to an increased risk of CDD for children and indicate the possibility for an integrated strategy to assess CDD risk and improve children’s cognitive ability.

Authors: Yuanyuan Li, Ph.D., of the Huazhong University of Science and Technology in Wuhan, Hubei, China, is the corresponding author.

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(doi:10.1001/jamanetworkopen.2023.39108)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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Prenatal lead exposure, genetic factors, and cognitive developmental delay

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