PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Ground-breaking accelerated discovery research unveils 21 novel materials for advanced organic solid-state laser technology: a global collaboration success story

Researchers from six teams in five labs from around the world used self-driving labs to reduce materials discovery time down from years to only a few months

2024-05-16
(Press-News.org) Organic solid-state lasers (OSLs) hold immense promise for a wide range of applications due to their flexibility, colour tunability, and efficiency. However, they are difficult to make, and with over 150,000 possible experiments required to conduct to find successful new materials, discovering them all would be the work of several lifetimes. In fact, in the previous few decades, only 10-20 new OSL materials have been tested. Researchers with the Acceleration Consortium based at the University of Toronto, took up this challenge and used self-driving lab (SDL) technology that, once set up, enabled them to synthesize and test over 1000 potential OSL materials and discover at least 21 top performing OSL gain candidates in a matter of months.

An SDL uses advanced technologies such as artificial intelligence and robotic synthesis to streamline the process of identifying novel materials – in this case, materials with exceptional lasing properties. Up until now, SDLs have usually been confined to one physical lab in one geographic location. This paper titled "Delocalized Asynchronous Closed-Loop Discovery of Organic Laser Emitters" published in the journal Science, showcases how the research team used the concept of distributed experimentation, where tasks are divided among different research sites, to achieve the joint goal faster. For this research, labs from Toronto and Vancouver in Canada, Glasgow in Scotland, Illinois in the USA, and Fukuoka in Japan were involved.

By using this method, each lab was able to contribute its unique expertise and resources- which ultimately played a key role in the success of this project. This decentralized workflow, managed by a cloud-based platform, not only enhanced efficiency but also allowed for the rapid replication of experimental findings, ultimately democratizing the discovery process, and accelerating the development of next-generation laser technology.

“What this paper shows is that a closed-loop approach can be delocalized, researchers can go all the way down from the molecular state down to devices and you can accelerate the discovery of materials that are very early in the process of commercialization,” said Dr. Alán Aspuru-Guzik, director of the Acceleration Consortium. “The team designed an experiment that went all the way down from molecule to device- with the final devices being made in Japan. They were scaled up in Vancouver and then transferred to Japan for characterization.”

The discovery of these novel materials represents a significant advancement in the field of molecular optoelectronics. It has paved the way for enhanced performance and functionality in OSL devices and set a precedent for future delocalized discovery campaigns in the field of materials science and self-driving labs.

 

About the Acceleration Consortium

The Acceleration Consortium is a network of government, academia, and industry working to accelerate the discovery of materials. Based at the University of Toronto, the AC accelerates materials discovery by developing robust and scalable self-driving labs (SDLs). SDLs combine AI, robotics, and high-throughput experimentation to develop new materials with a desired functionality. As recipients a $200 million Canada First Research Excellence Fund (CFREF) grant - the largest ever by a Canadian university - the AC is building capacity to accelerate the design and commercialization of materials for sustainability and health applications to help society solve some of its most significant challenges. Visit acceleration.utoronto.ca to learn more.

END


ELSE PRESS RELEASES FROM THIS DATE:

Otters, especially females, use tools to survive a changing world

Otters, especially females, use tools to survive a changing world
2024-05-16
Sea otters are one of the few animals that use tools to access their food, and a new study has found that individual sea otters that use tools — most of whom are female — are able to eat larger prey and reduce tooth damage when their preferred prey becomes depleted. The study researchers and their enlisted volunteer “otter spotters” followed 196 radio-tagged southern sea otters off the coast of California to better understand how the threatened species uses tools in a rapidly changing environment. The research team from The University ...

Military physicians give high-ranking military patients preferential treatment over lower-ranking patients

2024-05-16
Military physicians give patients whose military rank is higher better treatment than those who rank lower, according to a new study involving 1.5 million patient encounters. The findings provide evidence that the powerful enjoy better resources and support in a clinical context, often at the expense of the less powerful. “Our concern does not lie with the doctor-patient power imbalance itself, which is likely necessary for effective physician performance,” write the authors. “Rather, it lies with the inequitable variation in how that power is exercised, with the most vulnerable patients likely bearing the burden of this disparity, as ...

Tool use promotes foraging success and dental health in sea otters

2024-05-16
Using tools, like shells and rocks, to open their often thick-shelled mollusk prey increases foraging success in sea otters and protects their teeth from damage by allowing the animals to eat prey that would otherwise be difficult to obtain. The findings suggest that this behavior is a necessity for the survival of some otters in environments where competition is high and preferred prey is in short supply. Sea otters are well-known tool users. Aside from crushing prey with their teeth, sea otters have been observed using rocks, shells, human litter, and even the hulls of boats to bash open hard prey, including ...

Advances in priming B cell immunity against HIV pave the way to future HIV vaccines, shows quartet of new studies

2024-05-16
Scientists have made several advances in the design of a class of HIV vaccines that could offer broad protection against the virus, according to four new research papers published this week in Science, Science Translational Medicine, and Science Immunology. “The studies […] exemplify progress in the rational design of [germline-targeting] HIV-1 vaccines, and what is being learned will guide [germline-targeting] programs for inducing [broadly neutralizing antibodies] against other human pathogens,” Rogier Sanders and John Moore write in a related ...

Total energy cost of animal reproduction is higher than previously assumed

2024-05-16
The energy invested in animal reproduction is as much as 10 times greater than previously estimated when the metabolic load of bearing and caring for offspring is accounted for, according to a new study. The findings fundamentally challenge longstanding theories and biological models of animal growth and life histories. The act of reproduction is one of the largest energy investments an animal can make. This investment includes direct cost, the energy directly invested in the offspring themselves, and indirect costs, the energy expended to create, carry, and care for offspring before they are born. While the direct costs of reproduction are well understood, the indirect ...

Researchers discover new pathway to cancer cell suicide

Researchers discover new pathway to cancer cell suicide
2024-05-16
Researchers discover new pathway to cancer cell suicide Chemotherapy kills cancer cells. But the way these cells die appears to be different than previously understood. Researchers from the Netherlands Cancer Institute, led by Thijn Brummelkamp, have uncovered a completely new way in which cancer cells die: due to the Schlafen11 gene. "This is a very unexpected finding. Cancer patients have been treated with chemotherapy for almost a century, but this route to cell death has never been observed before. Where and when this occurs in patients will need to be further investigated. This discovery could ultimately have implications for the treatment of cancer patients." They publish their ...

Researchers wrestle with accuracy of AI technology used to create new drug candidates

Researchers wrestle with accuracy of AI technology used to create new drug candidates
2024-05-16
CHAPEL HILL, N.C. – Artificial intelligence (AI) has numerous applications in healthcare, from analyzing medical imaging to optimizing the execution of clinical trials, and even facilitating drug discovery. AlphaFold2, an artificial intelligence system that predicts protein structures, has made it possible for scientists to identify and conjure an almost infinite number of drug candidates for the treatment of neuropsychiatric disorders. However recent studies have sown doubt about the accuracy of AlphaFold2 in modeling ligand binding sites, the areas on proteins where drugs attach and begin signaling ...

Breaking bonds to form bonds: Rethinking the Chemistry of Cations

Breaking bonds to form bonds: Rethinking the Chemistry of Cations
2024-05-16
A team of chemists from the University of Vienna, led by Nuno Maulide, has achieved a significant breakthrough in the field of chemical synthesis, developing a novel method for manipulating carbon-hydrogen bonds. This groundbreaking discovery provides new insights into the molecular interactions of positively charged carbon atoms. By selectively targeting a specific C–H bond, they open doors to synthetic pathways that were previously closed – with potential applications in medicine. The study was recently published in the prestigious journal Science. Living ...

New gene delivery vehicle shows promise for human brain gene therapy

2024-05-16
In an important step toward more effective gene therapies for brain diseases, researchers from the Broad Institute of MIT and Harvard have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein. Because the vehicle binds to a well-studied protein in the blood-brain barrier, the scientists say it has a good chance at working in patients. Gene therapy could potentially treat a range of severe genetic brain disorders, which currently ...

Finding quantum order in chaos

2024-05-16
If you zoom in on a chemical reaction to the quantum level, you’ll notice that particles behave like waves that can ripple and collide. Scientists have long sought to understand quantum coherence, the ability of particles to maintain phase relationships and exist in multiple states simultaneously; this is akin to all parts of a wave being synchronized. It has been an open question whether quantum coherence can persist through a chemical reaction where bonds dynamically break and form. Now, for the first time, a team of Harvard scientists has demonstrated the survival of quantum coherence in a chemical reaction involving ultracold molecules. These findings highlight the potential of ...

LAST 30 PRESS RELEASES:

Students with multiple marginalized identities face barriers to sports participation

Purdue deep-learning innovation secures semiconductors against counterfeit chips

Will digital health meet precision medicine? A new systematic review says it is about time

Improving eye tracking to assess brain disorders

Hebrew University’s professor Haitham Amal is among a large $17 million grant consortium for pioneering autism research

Scientists mix sky’s splendid hues to reset circadian clocks

Society for Neuroscience 2024 Outstanding Career and Research Achievements

Society for Neuroscience 2024 Early Career Scientists’ Achievements and Research Awards

Society for Neuroscience 2024 Education and Outreach Awards

Society for Neuroscience 2024 Promotion of Women in Neuroscience Awards

Baek conducting air quality monitoring & simulation analysis

Albanese receives funding for scholarship grant program

Generative AI model study shows no racial or sex differences in opioid recommendations for treating pain

New study links neighborhood food access to child obesity risk

Efficacy and safety of erenumab for nonopioid medication overuse headache in chronic migraine

Air pollution and Parkinson disease in a population-based study

Neighborhood food access in early life and trajectories of child BMI and obesity

Real-time exposure to negative news media and suicidal ideation intensity among LGBTQ+ young adults

Study finds food insecurity increases hospital stays and odds of readmission 

Food insecurity in early life, pregnancy may be linked to higher chance of obesity in children, NIH-funded study finds

NIH study links neighborhood environment to prostate cancer risk in men with West African genetic ancestry

New study reveals changes in the brain throughout pregnancy

15-minute city: Why time shouldn’t be the only factor in future city planning

Applied Microbiology International teams up with SelectScience

Montefiore Einstein Comprehensive Cancer Center establishes new immunotherapy institute

New research solves Crystal Palace mystery

Shedding light on superconducting disorder

Setting the stage for the “Frankfurt Alliance”

Alliance presents final results from phase III CABINET pivotal trial evaluating cabozantinib in advanced neuroendocrine tumors at ESMO 2024 and published in New England Journal of Medicine

X.J. Meng receives prestigious MERIT Award to study hepatitis E virus

[Press-News.org] Ground-breaking accelerated discovery research unveils 21 novel materials for advanced organic solid-state laser technology: a global collaboration success story
Researchers from six teams in five labs from around the world used self-driving labs to reduce materials discovery time down from years to only a few months