PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Inhaler misuse leads to mismanagement of COPD symptoms, increased exacerbations

Patients need additional education on proper inhaler use to improve outcomes

2024-08-20
(Press-News.org) MIAMI (August 20, 2024) – Inhaler misuse leading to inadequate medication delivery impacts a person’s ability to manage symptoms of chronic obstructive pulmonary disease (COPD), and additional education about proper inhaler use is needed to improve health outcomes, according to two new articles. The articles are published in the July 2024 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open-access journal.

COPD comprises several conditions, including chronic bronchitis and emphysema, and can be caused by irritants like smoke or pollution and genetics. The disease affects more than 30 million Americans, yet awareness of the disease’s symptoms, methods to reduce risk, and disease management remains poor. Symptoms, which include breathlessness, fatigue, and chronic cough, are primarily treated using inhaled medications.

In a new study, “Prevalence of Critical Errors and Insufficient Peak Inspiratory Flow in Patients Hospitalized With COPD in a Department of General Internal Medicine: A Cross-Sectional Study,” the authors examined how often inhalers were misused by patients hospitalized with COPD over the course of nine months at Fribourg Hospital in Switzerland.    

Inhaler misuse was categorized as either a critical error in inhalation technique or insufficient peak inspiratory flow. These errors result in a lesser dose of medication reaching the person’s lungs, which impacts the person’s ability to manage their symptoms and can lead to increased exacerbations.   

“Misuse of inhalers is common, and in our study, we found that approximately two-thirds of inhalers were misused,” said Gaël Grandmaison, M.D., an assistant physician in internal medicine at University and Hospital of Fribourg in Fribourg, Switzerland. “If an inhaler was misused, a physiotherapist conducted up to three teaching sessions with the patient. These sessions helped reduce the number of critical errors in inhaler use. However, despite this education, more than one in 10 inhalers continued to be used suboptimally, either due to an inability to generate sufficient inspiratory effort or because the inhaler was unsuitable for the patient’s characteristics. These results highlight the importance of regular therapeutic education, assessing the patient’s ability to generate a sufficient inspiratory effort, and selecting an inhaler suited to the patient’s characteristics.”

In a perspective article, “Real-World Use of Inhaled COPD Medications: the Good, the Bad, the Ugly,” the author discusses the decreased effectiveness of inhaled medications as the result of inhaler misuse (often due to intricacies and multiple steps required to use the inhaler) and the high cost of inhaler-based therapies. The author also highlights several advances in inhaler use, including the ability to combine therapies and to choose the right inhaler based on patient-centered decisions.

“Education is key to increasing the effectiveness of inhaled medications, and many clinicians – and often even the patients themselves – are unaware that patients are having difficulty getting enough medication into their lungs,” said Valerie G. Press, M.D., MPH, an associate professor of medicine at the University of Chicago. “Additional inhaler technique education is needed to ensure patients are using the device correctly, especially when multiple inhaled medications are prescribed. Additional education, supported by the necessary resources, would help ensure patients are receiving optimal treatment and avoiding adverse health outcomes.”

To access current and past issues of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, visit journal.copdfoundation.org.

###

About the COPD Foundation
The COPD Foundation is a nonprofit organization whose mission is to help millions of people live longer and healthier lives by advancing research, advocacy, and awareness to stop COPD, bronchiectasis, and NTM lung disease. The Foundation does this through scientific research, education, advocacy, and awareness to prevent disease, slow progression, and find a cure. For more information, visit copdfoundation.org, or follow us on Twitter and LinkedIn.

 

END



ELSE PRESS RELEASES FROM THIS DATE:

Growth from adversity: How older adults bounced back from the COVID-19 pandemic

Growth from adversity: How older adults bounced back from the COVID-19 pandemic
2024-08-20
During a pandemic, attention is usually focused on the immediate challenges, such as managing the disease, ensuring safety and coping with disruptions in daily routines. Adversity, while difficult, can sometimes lead to positive effects.   For older adults living in retirement communities, there has been limited research on how the COVID-19 pandemic and its regulatory measures affected them. Additionally, there is scant research on any potential positive effects for this population. Now, a new study of 98 older adults (median age 86 years) living in a continuing care retirement community in South Florida during COVID-19 reveals ...

The University of Texas at San Antonio tackles research security threats with $67 million NSF grant

The University of Texas at San Antonio tackles research security threats with $67 million NSF grant
2024-08-20
UTSA will partner with Texas A&M University to co-lead SECURE Southwest, one of five new regional centers being launched to strengthen U.S. research security. Under a five-year, $67 million award from the National Science Foundation (NSF), the Safeguarding the Entire Community of the U.S. Research Ecosystem (SECURE) Center aims to strengthen intellectual property and research security by educating members of the research community about security issues and engaging them in a process of collaborative problem-solving. The ...

Computer scientists discover vulnerabilities in a popular security protocol

Computer scientists discover vulnerabilities in a popular security protocol
2024-08-20
A widely used security protocol that dates back to the days of dial-up Internet has vulnerabilities that could expose large numbers of networked devices to an attack and allow an attacker to gain control of traffic on an organization's network. A research team led by University of California San Diego computer scientists investigated the Remote Authentication Dial-In User Service (RADIUS) protocol and found a vulnerability they call Blast-RADIUS that has been present for decades. RADIUS, designed in 1991, allows networked devices such as routers, switches or mobile roaming gear to use a remote server to validate login or other credentials.  This is a common set-up in enterprise and ...

The emergence of moral foundations in children’s speech

2024-08-20
A study of children’s conversations with their caretakers sheds light on the timeline of the emergence of moral foundation words in the first six years of life in English-speaking children. Moral Foundations theory posits that morality is largely intuitive and underlaid by modular foundations. The original set of five foundations proposed by researchers includes Care/Harm, Fairness/Cheating, Authority/Subversion, Loyalty/Betrayal, and Purity/Degradation. Aida Ramezani and colleagues systematically ...

Correcting misperceptions of opposing party won’t reduce polarization

2024-08-20
Political animus between Republicans and Democrats in the United States is alarmingly high, raising fears of undemocratic or even violent actions. An often-touted intervention to prevent political polarization is to identify and correct misperceptions about people’s partisan opponents. Sean Westwood and colleagues sought to empirically test the effectiveness of this strategy. The authors surveyed 9,810 American partisans online from fall 2022 to fall 2023, finding that their opinions of whether ...

Scientists discover new code governing gene activity

2024-08-20
A newly discovered code within DNA – coined “spatial grammar” – holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding, identified by researchers at Washington State University and the University of California, San Diego and published in Nature, revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists’ understanding of gene regulation and how genetic variations may influence gene expression in development or disease. Transcription factors, the proteins that control which genes in one’s genome are turned on or off, ...

The invasion of Ukraine and European attitudes

2024-08-20
An ongoing survey captures how the Russian invasion of Ukraine affected attitudes in European countries not directly involved in the conflict. Margaryta Klymak and Tim Vlandas examine how the Russian invasion of Ukraine affected economic and political attitudes in eight European countries. The authors took advantage of the timing of the European Social Survey (ESS), which happened to be administered both just before and just after the Russian invasion of Ukraine in February 2022 in eight countries: Switzerland, Greece, Italy, Montenegro, Macedonia, Netherlands, Norway, and Portugal. Overall, the invasion increased support ...

A new reaction to enhance aromatic ketone use in chemical synthesis

A new reaction to enhance aromatic ketone use in chemical synthesis
2024-08-20
Aromatic ketones have long been valuable intermediates in chemical synthesis, particularly in cross-coupling reactions where different chemical entities are combined to form new compounds. For instance, a process called deacylative cross-coupling removes the acyl group from the aromatic ketone, allowing it to bond with other chemicals and produce a wide variety of useful compounds. These reactions are crucial for producing a wide array of aromatic compounds used in various industries like agrochemicals. However, the utility of aromatic ketones has been limited due to the difficulty in breaking their strong carbon-carbon bonds. These robust bonds are challenging to cleave, ...

Investigating the interplay of folding and aggregation in supramolecular polymer systems

Investigating the interplay of folding and aggregation in supramolecular polymer systems
2024-08-20
In polymers, the competition between the folding and aggregation of chains, both at an individual level and between chains, can determine the mechanical, thermal, and conductive properties of such materials. Understanding the interplay of folding and aggregation presents a significant opportunity for the development and discovery of polymeric materials with tailored properties and functionalities. This also holds true for non-covalent counterparts of conventional covalent polymers, i.e., supramolecular polymers (SPs). SPs are expected to have practical applications as novel stimuli-responsive ...

Adaptive 3D printing system to pick and place bugs and other organisms

Adaptive 3D printing system to pick and place bugs and other organisms
2024-08-20
MINNEAPOLIS / ST. PAUL (08/20/2024) — A first-of-its-kind adaptive 3D printing system developed by University of Minnesota Twin Cities researchers can identify the positions of randomly distributed organisms and safely move them to specific locations for assembly. This autonomous technology will save researchers time and money in bioimaging, cybernetics, cryopreservation, and devices that integrate living organisms. The research is published in Advanced Science, a peer-reviewed scientific journal. The researchers ...

LAST 30 PRESS RELEASES:

How molecules can ‘remember’ and contribute to memory and learning

New research links global climate patterns to wildfires in Los Angeles

The RESIL-Card project is piloting its resilience assessment tool across Europe.

Researchers identify molecular brake that regulates synaptic maturation

Study links residual inflammation in psoriasis patients to obesity and fatty liver disease

Vaping increases dependency more than nicotine gum

New scientific articles highlight potential link between microplastics in ultra-processed foods and brain health

New study reveals how 5'LysTTT tRNA fragments protect neurons during botulinum toxin exposure

Prader-Willi syndrome reveals unique link between genetics and psychiatric disorders

Dynamic memory engrams reveal how the brain forms, stores, and updates memories

Researchers decode neural pathways of cognitive flexibility across species

Research team traces evolutionary history of bacterial circadian clock on ancient Earth

Majority of youth overdose deaths from 2018 to 2022 were driven by fentanyl alone

Reducing wait times for hip and knee replacement surgeries

Clinician entrepreneurs can benefit Canada’s health and economy

Scientists discover NELL2’s dual role: boosting bone formation while curbing fat accumulation

Bees facing new threats, putting our survival and theirs at risk

Deep learning can predict lung cancer risk from single LDCT scan

Genomic data shows widespread mpox transmission in West Africa prior to 2022 global outbreak

Research spotlight: Gender differences in primary care physician earnings and outcomes

Eating craved foods with meals lessens cravings, boosts weight loss

Limited evidence suggests calorie restriction may slightly reduce depressive symptoms in people with elevated cardiometabolic risk

U of A researchers developing world's first petahertz-speed phototransistor in ambient conditions

NRL hosts Innovation Day for Industry

Here comes the boom! Studying the effects of rocket launch sonic booms on neighboring communities #ASA188

Researchers capture brain activity with imager that is smaller than an eyelash

A head and a hundred tails: how a branching worm manages reproductive complexity

Investment risk for energy infrastructure construction is highest for nuclear power plants, lowest for solar

Personality traits influence the development of insomnia

Controlling these 8 risk factors may eliminate early death risk for those with high blood pressure

[Press-News.org] Inhaler misuse leads to mismanagement of COPD symptoms, increased exacerbations
Patients need additional education on proper inhaler use to improve outcomes