PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

National Mental Health Institute awards CAD 45 million to develop mental health treatments 

Sylvain Bouix, professor-researcher at École de technologie supérieure (ÉTS), in Montréal, to Lead a Research Team 

National Mental Health Institute awards CAD 45 million to develop mental health treatments 
2024-11-06
(Press-News.org) One out of 100 people will experience a psychotic episode in their lifetime, and these usually appear in late adolescence or early adulthood. A Canada-US team consisting of Sylvain Bouix, from École de technologie supérieure (ÉTS), Martha E. Shenton and Ofer Pasternak, from the Brigham and Women’s Hospital (Harvard University), and René Kahn, from Mount Sinai Hospital (New York) has just received US $33 million in funding—the equivalent of CAD 45 million—over five years from the National Institute of Mental Health to better understand the mechanisms of action of new drugs designed to treat psychosis.

With this funding, a research team led by Sylvain Bouix of ÉTS will set up a center to coordinate processing and analysis of data for the proof of principle clinical trial.

“Although promising therapeutic targets have been discovered for this high-risk population, their validation is difficult due to the lack of reliable biomarkers to predict disease progression. Moreover, the diversity of symptoms, such as anxiety or depression, further complicates matters. The development of new data analysis tools could help design clinical trials better adapted to patients’ actual needs.”

More specifically, Professor Bouix and his team will ensure the quality of the data collected, from behavioral and clinical measures to electroencephalography, magnetic resonance imaging and audiovisual recordings, to name but a few.

This is an essential step, as data quality is key to obtaining reliable and accurate results in clinical trials. Data quality also ensures the scientific robustness, personal safety and regulatory acceptance of the new therapies and medical interventions to be developed in the future.

About Sylvain Bouix

Professor in the Department of Software Engineering and Information Technology at ÉTS since 2022, Sylvain Bouix holds the Canada Research Chair in Neuroinformatics for Multimodal Data. Before joining ÉTS, he was a senior researcher at Harvard University’s Brigham and Women’s Hospital. He earned a master’s degree in computer science from the University of Kansas in 1998 and a PhD from McGill University in 2003. Professor Bouix’s expertise lies in healthcare technologies, focusing on medical imaging, neuroimaging, neuroinformatics, and anatomical and diffusion-weighed MRI.  Since 2020, Professor Bouix has been collaborating on a large-scale international study, involving over forty countries, of young adults at high risk of developing psychosis.

About ÉTS

École de technologie supérieure is one of ten constituents of the Université du Québec network (located in Montreal, Canada). It trains engineers and researchers who are recognized for their practical and innovative approach, the development of new technologies and their skill at transferring their knowledge to companies. Almost one-quarter of all engineers in Québec graduated from ÉTS, which boasts 11,000 students, including 2,650 at the graduate and post-graduate level. ÉTS specializes in applied training and research in engineering, and maintains a unique partnership with the business sector and with industry. For more information, please visit etsmtl.ca.

END


[Attachments] See images for this press release:
National Mental Health Institute awards CAD 45 million to develop mental health treatments 

ELSE PRESS RELEASES FROM THIS DATE:

Washington coast avian flu outbreak devastated Caspian terns, jumped to seals

Washington coast avian flu outbreak devastated Caspian terns, jumped to seals
2024-11-06
PULLMAN, Wash. – An epidemiological study found that 56% of a large breeding colony of Caspian terns died from a 2023 outbreak of highly pathogenic avian influenza at Rat Island in Washington state. Since then, no birds have successfully bred on the island, raising concerns that the outbreak may have had a significant impact on an already declining Pacific-coast population. As part of the study, a team including Washington Department of Fish and Wildlife (WDFW) as well as Washington State University researchers also documented that the avian flu virus H5N1was transmitted to harbor seals for the first time in the northeastern ...

Mice tails whip up new insights into balance and neurodegenerative disease research

Mice tails whip up new insights into balance and neurodegenerative disease research
2024-11-06
Why do mice have tails? The answer to this is not as simple as you might think. New research from the Okinawa Institute of Science and Technology (OIST) has shown that there’s more to the humble mouse tail than previously assumed. Using a novel experimental setup involving a tilting platform, high-speed videography and mathematical modelling, scientists have demonstrated how mice swing their tails like a whip to maintain balance – and these findings can help us better understand balance issues in humans, paving the way for spotting and treating neurodegenerative diseases like multiple ...

New study: Earthquake prediction techniques lend quick insight into strength, reliability of materials

New study: Earthquake prediction techniques lend quick insight into strength, reliability of materials
2024-11-06
CHAMPAIGN, Ill. — Materials scientists can now use insight from a very common mineral and well-established earthquake and avalanche statistics to quantify how hostile environmental interactions may impact the degradation and failure of materials used for advanced solar panels, geological carbon sequestration and infrastructure such as buildings, roads and bridges. The new study, led by the University of Illinois Urbana-Champaign in collaboration with Sandia National Laboratories and Bucknell University, shows that the amount ...

Vitamin D during pregnancy boosts children’s bone health even at age seven

2024-11-06
Vitamin D during pregnancy boosts children’s bone health even at age seven Children whose mothers took extra vitamin D during pregnancy continue to have stronger bones at age seven, according to new research led by the University of Southampton and University Hospital Southampton (UHS). Bone density scans revealed that children born to mothers who were given vitamin D supplements during pregnancy have greater bone mineral density in mid-childhood. Their bones contain more calcium and other minerals, making them stronger and less likely to break. Researchers say the findings, published in The American Journal of Clinical Nutrition,   reinforce the importance of ...

Use of “genetic scissors” carries risks

2024-11-06
The CRISPR molecular scissors have the potential to revolutionize the treatment of genetic diseases. This is because they can be used to correct specific defective sections of the genome. Unfortunately, however, there is a catch: under certain conditions, the repair can lead to new genetic defects – as in the case of chronic granulomatous disease. This was reported by a team of basic researchers and physicians from the clinical research program ImmuGene at the University of Zurich (UZH). Chronic granulomatous disease is ...

Does work-related stress compromise cardiovascular health?

2024-11-06
In a large multi-ethnic group of adults in the United States without cardiovascular disease, those with work-related stress were more likely to have unfavorable measures of cardiovascular health. The findings are published in the Journal of the American Heart Association. For the analysis, investigators assessed data collected between 2000 and 2002 for 3,579 community-based men and women aged 45–84 years enrolled in the Multi-Ethnic Study of Atherosclerosis. Cardiovascular health was determined based on seven metrics—smoking, physical activity, body mass index, diet, total cholesterol, blood pressure, and blood glucose—with each metric contributing zero points, ...

New research may lead to potatoes that are less reliant on nitrogen fertilizers

2024-11-06
Because nitrogen fertilizers contribute to global greenhouse gas emissions, scientists are looking for ways to modify agricultural plants so that they rely on less nitrogen. In research published in New Phytologist, investigators have found that blocking a particular protein may achieve this goal in potatoes. The protein, called Solanum tuberosum CYCLING DOF FACTOR 1 (StCDF1), binds to DNA and plays a key role in regulating tuberization in potatoes. In this latest research, investigators found that StCDF1 ...

Do commercial ties influence ESG ratings?

2024-11-06
An analysis published in the Journal of Accounting Research uncovers evidence that conflicts of interest arising from commercial ties lead to bias in environmental, social, and governance (ESG) ratings. Investigators focused on Moody’s and S&P’s acquisitions of ESG rating agencies Vigeo Eiris and RobecoSAM. Their analysis revealed that after these ESG rating agencies were acquired by Moody’s and S&P, they issued higher ratings to existing paying clients of Moody’s and S&P. Specifically, ...

Study assesses "gendered space" in financial institutions in Pakistan

2024-11-06
In Islamic cultures, purdah, which literally means “curtain,” is a practice that involves the seclusion of women from public observation and the enforcement of high standards of female modesty. Research published in the Journal of Management Studies examines the significance of purdah (spatial modesty) in gender relations in financial institutions in Pakistan. The research was based on the lived experiences of women and men working in two banks based in Pakistan. One of the study’s co-authors, Shafaq Chaudhry, PhD, of the University of Central Lancashire, in the UK, sought internships for six weeks ...

Chinese herbal medicine’s potential in preventing dementia

Chinese herbal medicine’s potential in preventing dementia
2024-11-06
Attempts to discover a breakthrough dementia drug might be drawing attention these days, but traditional medicinal products can offer hints for preventive medicine. A research group led by Specially Appointed Professor Takami Tomiyama of Osaka Metropolitan University’s Graduate School of Medicine has found that administering the dried seeds of a type of jujube called Ziziphus jujuba Miller var. spinosa, used as a medicinal herb in traditional Chinese medicine, holds promise in restoring cognitive and motor function in model mice. By administering hot water extracts of Zizyphi spinosi semen to model mice with ...

LAST 30 PRESS RELEASES:

Lurie Children’s campaign urges parents to follow up right away if newborn screening results are abnormal

Does drinking alcohol really take away the blues? It's not what you think

Speed of risk perception is connected to how information is arranged

High-risk pregnancy specialists analyze AI system to detect heart defects on fetal ultrasound exams

‘Altar tent’ discovery puts Islamic art at the heart of medieval Christianity

Policy briefs present approach for understanding prison violence

Early adult mortality is higher than expected in US post-COVID

Recycling lithium-ion batteries cuts emissions and strengthens supply chain

Study offers new hope for relieving chronic pain in dialysis patients

How does the atmosphere affect ocean weather?

Robots get smarter to work in sewers

Speech Accessibility Project data leads to recognition improvements on Microsoft Azure

Tigers in the neighborhood: How India makes room for both tigers and people

Grove School’s Arthur Paul Pedersen publishes critical essay on scientific measurement literacy

Moffitt study finds key biomarker to predict KRASG12C inhibitor effectiveness in lung cancer

Improving blood transfusion monitoring in critical care patients: Insights from diffuse optics

Powerful legal and financial services enable kleptocracy, research shows

Carbon capture from constructed wetlands declines as they age

UCLA-led study establishes link between early side effects from prostate cancer radiation and long-term side effects

Life cycles of some insects adapt well to a changing climate. Others, not so much.

With generative AI, MIT chemists quickly calculate 3D genomic structures

The gut-brain connection in Alzheimer’s unveiled with X-rays

NIH-funded clinical trial will evaluate new dengue therapeutic

Sound is a primary issue in the lives of skateboarders, study shows

Watch what you eat: NFL game advertisements promote foods high in fat, sodium

Red Dress Collection Concert hosted by Sharon Stone kicks off American Heart Month

One of the largest studies on preterm birth finds a maternal biomarker test significantly reduces neonatal morbidities and improves neonatal outcomes

One of the largest studies of its kind finds early intervention with iron delivered intravenously during pregnancy is a safe and effective treatment for anemia

New Case Western Reserve University study identifies key protein’s role in psoriasis

First-ever ethics checklist for portable MRI brain researchers

[Press-News.org] National Mental Health Institute awards CAD 45 million to develop mental health treatments 
Sylvain Bouix, professor-researcher at École de technologie supérieure (ÉTS), in Montréal, to Lead a Research Team