Screening history, stage at diagnosis, and mortality in screen-detected breast cancer

JAMA Network Open

2025-04-15

(Press-News.org) About The Study: In this cohort study of older women with screen-detected estrogen receptor–positive or human epidermal growth factor receptor 2–negative breast cancer, prior screening mammography was associated with earlier stage at breast cancer diagnosis and lower breast cancer mortality. These findings support the potential for routine screening to improve breast cancer outcomes. As with all observational studies, this study is limited by the potential effects of other differences between the screening and nonscreening groups.

Corresponding Author: To contact the corresponding author, Michaela A. Dinan, PhD, email michaela.dinan@yale.edu.

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(doi:10.1001/jamanetworkopen.2025.5322)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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