Screening history, stage at diagnosis, and mortality in screen-detected breast cancer

JAMA Network Open

2025-04-15

(Press-News.org) About The Study: In this cohort study of older women with screen-detected estrogen receptor–positive or human epidermal growth factor receptor 2–negative breast cancer, prior screening mammography was associated with earlier stage at breast cancer diagnosis and lower breast cancer mortality. These findings support the potential for routine screening to improve breast cancer outcomes. As with all observational studies, this study is limited by the potential effects of other differences between the screening and nonscreening groups.

Corresponding Author: To contact the corresponding author, Michaela A. Dinan, PhD, email michaela.dinan@yale.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.5322)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.5322?guestAccessKey=c0957767-f5eb-4d6d-88a4-15c747418b57&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=041525

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

Pitt researchers release Phage images with unprecedented detail

2025-04-15

Researchers at Pitt have produced the most detailed image to date of a bacteriophage–phage for short–that has allowed them to see for the first time the structural makeup of the part of the phage that directly attaches to its target Mycobacterium cell. “Now you've got like a spec sheet for going in and designing phages so that they’ll bind to different kinds of cells,” said Graham Hatfull, the Eberly Family Professor of Biotechnology in the Kenneth P. Dietrich School of Arts and Sciences. That’s important because of what a phage, which is a kind of virus, does after it binds to a bacterial cell: it pierces a hole in the cell membrane and injects ...

Sound wave research for breast cancer receives $5.5 million

2025-04-15

University of Virginia researcher Natasha D. Sheybani, PhD, has received $5.5 million from the federal Department of Defense to support her cutting-edge efforts to use focused sound waves to improve our immune system’s ability to battle breast cancer. Sheybani, the research director of UVA’s Focused Ultrasound Cancer Immunotherapy Center, was the only scientist in the nation selected to receive a Breast Cancer Research Program Era of Hope Scholar Award in the latest funding round; she is UVA’s first recipient of the award. She will use the grant to advance her research into the potential of focused ultrasound to improve the safety, ...

Gene variant linked to benign prostate hyperplasia risk in Lebanese men

2025-04-15

“Our results indicate a strong association between certain genotypes of the SNP -765 G>C of the PTGS2 gene and BPH.” BUFFALO, NY – April 15, 2025 – A new research paper was published in Oncotarget, Volume 16, on April 4, 2025, titled “Association between two single nucleotide polymorphisms of the Prostaglandin-Endoperoxide Synthase 1 and 2 genes and cell proliferative prostatic diseases in Lebanon.” The team of researchers led by first author Brock J. Sheehan and corresponding author Ruhul H. Kuddus, from Utah Valley University, discovered that a specific genetic variation ...

Teoxane announces new study reinforcing the biocompatibility, safety and efficacy of RHA®4 in dynamic facial support

2025-04-15

Teoxane reinforces its commitment to scientific innovation with the publication of a new study in Plastic and Reconstructive Surgery – Global Open, providing robust preclinical and clinical evidence on the safety, biocompatibility, and performance of RHA®4* in midface augmentation. The study confirms that RHA®4[1], a resilient hyaluronic acid filler designed for dynamic facial areas[2],[3], integrates harmoniously within subcutaneous adipose tissue, preserving its natural biomechanics while delivering effective volume restoration. ...

Study identifies U.S. hotspots for drinking water quality violations and lack of access to safe, clean water

2025-04-15

Herndon, VA, March 25, 2025 -- About two million people in the United States lack access to running water or indoor plumbing in their homes. Another 30 million people live where drinking water systems violate safety rules. Water privatization -- the transfer of public water systems ownership and/or management to private companies -- has been proposed as a potential solution to provide more Americans with safe, clean drinking water. But opponents argue that private companies may prioritize profits over public needs. To investigate how ...

Busted! Researchers revolutionize fraud detection with machine learning

2025-04-15

Fraud is widespread in the United States and increasingly driven by technology. For example, 93% of credit card fraud now involves remote account access, not physical theft. In 2023, fraud losses surpassed $10 billion for the first time. The financial toll is staggering: credit card fraud costs $5 billion annually, affecting 60% of U.S. cardholders, while identity theft resulted in $16.4 billion in losses in 2021. Medicare fraud costs $60 billion each year, and government losses range from $233 billion to $521 billion annually, with improper payments totaling $2.7 trillion since 2003. Machine learning plays a critical ...

Earthworm-inspired multimodal pneumatic continuous soft robot enhanced by winding transmission

2025-04-15

A research paper by scientists at Tianjin University presented an earthworm-inspired multimodal pneumatic continuous soft robot enhanced by wire-winding transmission. The research paper, published on Mar. 19, 2025 in the journal Cyborg and Bionic Systems, proposes an earthworm-inspired multimodal pneumatic continuous soft robot to simultaneously achieve multimodal motion and good motion performance. Using the derived overlapped continuous control law (DOCCL) and wire-winding transmission, the robot can achieve a maximum planar crawling speed that surpasses that of other robots of the same type by an order of magnitude. With ...

Coastal heritage threatened by climate change

2025-04-15

Humans have always lived by coasts and waterways, and thus these locations are rich with archeological sites. Natural and cultural resource management are conducted separately, despite the fact that climate change, sea level rise, and extreme weather threaten them both. Jayur Mehta and colleagues argue a synergy of both approaches is required to protect coastal archaeological landscapes. The authors used LiDAR digital elevation models, site location data, and NOAA sea level rise models to define ...

A tale of two hummingbird bills 

2025-04-15

There are two species of streamertail hummingbirds on the island of Jamaica, West Indies—one with red-billed males (Trochilus polytmus) and the other with black-billed males (T. scitulus). This is a puzzling situation, as many evolutionary biologists have argued that avian speciation is unlikely to occur on small oceanic islands. Caroline Duffie Judy and colleagues investigated the hybrid zone that separates the two species, which is as narrow as 3.2 km. The authors analyzed 186 Trochilus specimens from 12 ...

Corn leads to improved performance in lithium-sulfur batteries

2025-04-15

PULLMAN, Wash. -- Researchers at Washington State University have demonstrated a way to use corn protein to improve the performance of lithium-sulfur batteries, a finding that holds promise for expanding the use of the high-energy, lighter-weight batteries in electric vehicles, renewable energy storage and other applications. Lithium-sulfur batteries are lighter for the same amount of energy and more environmentally friendly than commonly used lithium-ion batteries, but their commercial adoption has been limited by technological hurdles that shorten their lifespan. The WSU team’s research, published in the Journal of Power Sources, ...

Screening history, stage at diagnosis, and mortality in screen-detected breast cancer

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: