Multimodality treatment for metastatic lung cancer with surgery may improve survival rates
2015-06-10
Chicago, June 10, 2015 - Patients diagnosed with an advanced form of metastatic non-small cell lung cancer (NSCLC) may benefit from surgical resection (removal of all or part of the lung) in combination with chemotherapy and radiation therapy, according to an article in the June 2015 issue of The Annals of Thoracic Surgery.
Key points
Patients diagnosed with stage IIIB NSCLC may benefit from multimodality treatment that combines surgical resection in combination with chemotherapy or radiation therapy.
Surgery should be added to the treatment regimen only for carefully ...
Researchers uncover how a faulty gene can trigger fatal heart condition
2015-06-10
Dangerous heart rhythms called arrhythmias, often caused by undiagnosed heart conditions, can cause sudden cardiac arrests that take the lives of seemingly healthy young men and women including sports people.
A healthy, functioning heart has a regular electrical impulse that causes the heart to beat and pump blood around the body. If this impulse is interrupted or becomes irregular, it causes an abnormal heartbeat, called an arrhythmia. Arrhythmias can be a long-term condition, treated with medication or surgery or they can occur unexpectedly, suddenly stopping the heart ...
Europe's most homophobic countries may be paving the way for a rise in HIV cases
2015-06-10
Europe's most homophobic countries may be paving the way for a rise in HIV cases among gay and bisexual men, according to new research published in the journal AIDS.
An international team of researchers from Europe and the US looked at HIV-related service use, need and behaviours among 175,000 gay or bisexual men living in 38 European countries with differing levels of national homophobia.
They found that men in homophobic countries had fewer sexual partners and were less likely to be diagnosed with HIV. However, they also found those men knew less about HIV, were less ...
Microbe-mediated adaptation to a novel diet
2015-06-10
This news release is available in German.
Insects are the most diverse animal group on earth. Many of them feed on plants, and they are constantly challenged by the diverse direct and indirect defenses of their food plants as well as an imbalanced nutrient composition. In response, the insects are continuously evolving different behavioral, morphological and biochemical adaptations to overcome the plant defenses. Additionally, some species rely on symbiotic microbes to deal with the plants' nutritional challenges. Scientists of the Max Planck Research Group ...
Intensive initial therapy with triple DMARDs improves functional ability in early RA
2015-06-10
Rome, Italy, 10 June 2015: The results of the tREACH trial presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) Press Conference showed that initial therapy with combination DMARDs significantly improves measures of disease activity and functional ability in patients with early rheumatoid arthritis (RA). These findings suggest that an initial treatment regimen of methotrexate, sulfasalazine and hydroxychloroquine could provide significant patient benefits over monotherapy (methotrexate alone).
"Many trials have shown that early and intensive ...
Ultrasound-defined tenosynovitis identified as strong predictor of early RA
2015-06-10
Rome, Italy, 10 June 2015: The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) Press Conference showed that ultrasound diagnosis of tenosynovitis (inflammation of the tendon sheath) was superior to clinical symptoms and signs in the prediction of early Rheumatoid Arthritis (RA). This is the first study to show that ultrasound-defined tenosynovitis is a strong predictor of early RA. By identifying the need for treatment before the onset of symptoms and signs, this procedure has the potential to improve clinical outcomes. ...
Early intensive intervention improves outcomes for children with autism spectrum disorder
2015-06-10
Washington D.C., June 10, 2015 - A recent study published in the July 2015 issue of the Journal of the American Academy of Child and Adolescent Psychiatry demonstrates that early intervention, beginning between 18 and 30 months of age improves outcomes for children with autism spectrum disorder (ASD) at age 6.
Early intensive behavioral intervention is recognized an as efficacious approach for improving outcomes for young children with ASD. However, most studies of comprehensive, intensive intervention only report immediate outcomes at the end of intervention and the ...
Patients with moderate RA as likely to need joint surgery as those with high disease
2015-06-10
Rome, Italy, 10 June 2015: The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) Press Conference showed that patients with Rheumatoid Arthritis (RA) taking conventional DMARD therapy who have moderate disease activity have a similar risk of joint failure that requires surgery as those with high disease activity.
In some countries, additional treatment with a biological DMARD is based on a disease activity cut-off that excludes RA patients with moderate disease activity. These findings suggest it is not just ...
Ultrasound screening for abdominal aortic aneurysms: Advantages for men, but not for women
2015-06-10
Men benefit from one-time screening for abdominal aortic aneurysms via ultrasound. Studies provide proof that their risk of dying is reduced, the abdominal aorta ruptures less often, and emergency surgery can be avoided more often. Far fewer data are available for women and they show no relevant differences between the groups investigated. This is the result of the final report published on 28 May 2015 by the German Institute for Quality and Efficiency in Health Care (IQWiG).
Rupture is often fatal, even if emergency surgery is performed
An abdominal aortic aneurysm ...
Light pollution threatens the Balearic shearwater
2015-06-10
Petrel fledglings leave the nest after dark, but these marine birds' maiden flights towards the sea are hampered by city lights. Many collide or fall to the ground where they are in danger of being run over and vulnerable to predators. Now, a study has evaluated the impact of light pollution on three species of petrels on the Balearic Islands, including the Balearic shearwater, the most threatened sea bird in Europe, and concludes that between 30 and 47% of colonies are exposed to high levels of light pollution.
This is not a new phenomenon. The dangers that fledglings ...
Fast and accurate synchronization in the 'blink' of an eye
2015-06-10
"Let's synchronize our watches." It's the classic line before a group goes out on a mission. We are all familiar with the concept of synchronized clocks - less known, but equally important, is that wireless devices need to be synchronized too.
However, instead of requiring a precision of minutes, wireless devices have to make their clocks match within very small fractions of a second. This so-called "clock synchronization" is needed for a large range of purposes - from increasing cellphone coverage, to increasing data speed rates, to enabling precision localization in ...
Epic fails in 2015 elections: Does polling jeopardize fairness?
2015-06-10
Britain, Queensland, Israel, Poland - 2015 has been a year of electoral polling failure and it could have major implications on election outcomes, say QUT economics researchers.
The recent definitive Conservative win in the recent British elections, when polling had produced the near universal prediction of a 'hung parliament', mirrors Labor's surprise win in Queensland where the election outcome was unrelated to the poll prediction, says Professor Lionel Page from QUT's Queensland Behavioural Economics Group (QuBE).
"The magnitude of the failure to predict these elections' ...
First-ever observation of the native capside of a retrovirus
2015-06-10
This news release is available in Spanish. Bovine leukemia virus (BLV) is an infectious disease that affects the immune system of cattle, causing immunodeficiency and in some cases triggering the development of leukemia or solid tumors in the form of lymphomas. This illness causes significant losses in productivity and even premature death of animals mostly in dairy farms. It also raises sanitary barriers for commerce of livestock and derived goods. As such, it has become a very prevalent veterinary issue, notably in Uruguay, which needs urgent solving. BLV is a virus ...
Coral colonies more genetically diverse than assumed
2015-06-10
Coral colonies are more genetically diverse than it has been assumed to date. This is the conclusion drawn by biologists at Ruhr-Universität Bochum, who have conducted comprehensive studies into the genetic variability in individual colonies of different reef-forming coral species. "However, this doesn't mean we should expect that this variability can compensate for corals dying worldwide due to climate change," says Maximilian Schweinsberg from the Department of Animal Ecology, Evolution and Biodiversity, headed by Prof Dr Ralph Tollrian. In collaboration with colleagues, ...
PCOS sufferers appear to benefit from lifestyle modification combined with metformin
2015-06-10
A systematic review publishing today in the journal Human Reproduction Update has found that women who suffer from polycystic ovary syndrome (PCOS) could manage some of the symptoms by combining a change in lifestyle with taking the drug metformin.
PCOS is associated with a range of features including irregular cycles, infertility, obesity, diabetes, and depression. Researchers at Monash University in Australia compared the effects of change in lifestyle alone or with placebo, to lifestyle plus metformin. They found that lifestyle changes combined with taking metformin ...
New treatment hope for amyotrophic lateral sclerosis
2015-06-10
A previously unknown link between the immune system and the death of motor neurons in Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, has been discovered by scientists at the CHUM Research Centre and the University of Montreal. The finding paves the way to a whole new approach for finding a drug that can cure or at least slow the progression of such neurodegenerative diseases as ALS, Alzheimer's, Parkinson's and Huntington's diseases.
The study, published today in Nature Communications, shows that the immune system in the animal model C. elegans, ...
New study explores whether newborns delivered by c-section face higher risk of chronic health problems later in life
2015-06-10
New York, June 10 -- A new paper in the British Medical Journal by Jan Blustein, M.D., Ph.D., of New York University's Wagner School and a professor of Medicine and Population Health at NYU School of Medicine and Jianmeng Liu, M.D., Ph.D., of Peking University examines the evidence as to whether newborns delivered by Cesarean section are more likely to develop chronic diseases later in life. While the jury is still out and research is ongoing, recent studies underscore the need for health care providers to discuss with expectant parents the risk of babies born through cesarean ...
Companies are making cybersecurity a greater priority
2015-06-10
Companies are spending increasing amounts on cybersecurity tools, but aren't convinced their data is truly secure and many chief information security officers believe that attackers are gaining on their defenses, according to a new RAND Corporation study.
Charting the future of cybersecurity is difficult because so much is shrouded in secrecy, no one is entirely certain of all the methods malicious hackers use to infiltrate systems and businesses do not want to disclose their safety measures, according to the report.
While worldwide spending on cybersecurity is close ...
More women turning to CAM for menopause without medical guidance
2015-06-10
CLEVELAND, June 10 -- The use of complementary and alternative medicine (CAM) is increasing for the treatment of menopausal symptoms but often without the guidance of a clinician. That's according to a new study reported online today in Menopause, the journal of the North American Menopause Society (NAMS). As a result, the authors suggest that healthcare providers -- in particular family medicine practitioners -- need to be more aware of the various CAM therapies and take a more active role in guiding patients through their options to more safely and effectively coordinate ...
Stillbirth and neonatal death rate report identifies areas for improvement in NHS services
2015-06-10
Almost one in every 150 babies born in the UK is stillborn or dies soon after birth. A research team led from the University of Leicester has identified large differences across the UK in the numbers and rates of babies who die, even after taking account of known factors that influence the rate of death such as poverty, mother's age and ethnicity.
A new report by MBRRACE-UK*, a team of academics, clinicians and charity representatives (commissioned by the Healthcare Quality Improvement Partnership** as part of the Maternal, Newborn and Infant Clinical Outcome Review Programme), ...
Cuckoos mimic 'harmless' species as a disguise to infiltrate host nests
2015-06-10
Brood parasites are reproductive cheats that evolve ways of duping other birds into raising their young. Examples such as mimicry of host eggs, chicks and fledglings by brood parasitic eggs, chicks and fledglings are amongst the most iconic examples of animal deception in nature.
New research shows that adult brood parasitic female cuckoo finches have evolved plumage colours and patterns to mimic a harmless and abundant species, such as southern red bishops, to deceive possible host birds and reduce the risk of being attacked when approaching host nests to lay their eggs. ...
First live birth after transplantation of ovarian tissue frozen during childhood
2015-06-10
A young woman has become the first in the world to give birth to a healthy child after doctors restored her fertility by transplanting ovarian tissue that had been removed and frozen while she was a child.
A report of the case is published today in Human Reproduction [1], one of the world's leading reproductive medicine journals. While there have been reports of successful pregnancies after ovarian transplantation using tissue that had been removed from patients when they were adults, there have been none using tissue taken from girls before puberty and the ability of ...
Scientists downsize the giant 'Dreadnoughtus' dinosaur
2015-06-10
Scientists at the University of Liverpool have shown that the most complete giant sauropod dinosaur, Dreadnoughtus, discovered by palaeontologists in South America in 2014, was not as large as previously thought.
Found in Patagonia, the huge fossil had almost all of the major bones intact, allowing scientists to confidently estimate its overall size - measuring in at 26 metres long.
Preserved in rock, it is thought that the animal was close to maturity but not fully grown when it died, and may have grown to be even larger. The long-necked, plant-eating dinosaur was ...
Pigeon 'chain of command' aids navigation
2015-06-10
Having a hierarchical social structure with just a few well-connected leaders enables pigeon flocks to navigate more accurately on the wing, new research shows.
Hierarchical organisation also enables flocks to cope better with navigation errors made by individual birds.
Researchers from Oxford University and the Zoological Society of London created 'virtual flocks' of homing pigeons to test how different social networks affect the navigation performance of these groups. The team's simulations looked at everything from no networks (all connections between individuals ...
The Lancet Oncology: 2 large trials provide further evidence that 1 dose of HPV vaccine could prevent the majority of cervical cancers
2015-06-10
A single dose of the bivalent human papillomavirus (HPV) vaccine (Cervarix®, GlaxoSmithKline group of companies) may offer a similar level of protection against HPV-16/18 infections, which cause about 70% of cervical cancers, as the current two- and three-dose schedules, according to new research combining data from two large phase 3 trials published in The Lancet Oncology.
"Our findings question the number of HPV vaccine doses truly needed to protect the majority of women against cervical cancer, and suggest that a one-dose schedule should be further evaluated. ...
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