April 23, 2015, Vienna, Austria: A study revealed today at The International Liver Congress™ 2015 has demonstrated that alginate-enriched bread has the potential to inhibit fat digestion and circulatory lipids in patients with non-alcoholic fatty liver disease (NAFLD). Alginates are polysaccharides extracted from brown algae that are non-digestible in the upper gastrointestinal tract. Specific alginates are able to inhibit the activity of pancreatic lipase and thus reduce fat digestion and absorption. This study set out to determine if alginate-enriched bread inhibits ...

April 23, 2015, Vienna, Austria: Data revealed today at The International Liver CongressTM 2015 show that non-alcoholic fatty liver disease (NAFLD) plays a role in the early stages of coronary atherosclerosis and in its more severe form it can also promote the development of coronary artery calcification (CAC). Findings showed that the impact of NAFLD varies significantly depending on the severity of CAC at baseline. In those without CAC, NAFLD significantly affected the development of atherosclerosis; however, in patients with existing CAC at baseline NAFLD did not ...

Johns Hopkins Bloomberg School of Public Health researchers say that while a large majority of newborns are exposed in their earliest days to bisphenol A (BPA), a much-studied chemical used in plastics and in food and soda can linings, they can chemically alter and rid their bodies of it. The findings, published April 23 in The Journal of Pediatrics, challenge the current thinking on BPA toxicology. The U.S. Centers for Disease Control and Prevention has found that more than 92 percent of Americans ages six and older have BPA in their bodies, most likely through the consumption ...

Shortages of key antibiotics, including gold-standard therapies and drugs used to treat highly resistant infections, are on the rise, according to a new study of shortages from 2001 to 2013 published in Clinical Infectious Diseases and available online. The trends raise serious concerns about the effects on patient care, particularly for infections without effective alternative treatment options. "We found a tremendous number of drugs that are used to treat life threatening infections that just were not available," said study author Larissa May, MD, of George Washington ...

Rapid treatment with a new anti-inflammatory could have a major impact on recovery from spinal cord injury, University of Queensland researchers have found. UQ School of Biomedical Sciences' Dr Marc Ruitenberg and PhD student Ms Faith Brennan said they made the discovery during laboratory trials with an experimental drug. Ms Brennan said that excessive inflammation caused additional damage in spinal cord injuries and hindered recovery. "We found that a molecule called C5aR exacerbates inflammation and tissue damage after spinal cord injury," she said. "Our study ...

Tick-borne diseases are a major public health problem around the world. Ticks carry and transmit a variety of microbes that cause disease. These illnesses, which include Lyme disease, Rocky Mountain spotted fever, and Tularemia, can cause a variety of symptoms, often serious and sometimes deadly. Now, just in time for spring and the explosion of ticks in forests, lawns and trails, a new study by researchers from China and the University of Maryland School of Medicine (UM SOM) has uncovered a never-before-seen illness transmitted by ticks. It's possible that the disease ...

Researchers have pinpointed a primary cause of a rare skull disorder in infants, and the discovery could help wounded soldiers, car-wreck victims and other patients recover from disfiguring facial injuries. "This has a lot more implication than what we initially thought," said Yang Chai, a lead researcher on the study at the Herman Ostrow School of Dentistry of USC. "We can take advantage of these stem cells not only to repair a birth defect, but to provide facial regeneration for veterans or other people who have suffered traumatic injury." Chai predicted such treatment ...

SAN FRANCISCO--More than 143 million Americans living in the 48 contiguous states are exposed to potentially damaging ground shaking from earthquakes, with as many as 28 million people likely to experience strong shaking during their lifetime, according to research discussed at the annual meeting of Seismological Society of America. The report puts the average long-term value of building losses from earthquakes at $4.5 billion per year, with roughly 80 percent of losses attributed to California, Oregon and Washington. "This analysis of data from the new National Seismic ...

WEST LAFAYETTE, Ind. - A Purdue University study sheds light on how cell damage is reversed by the cancer drug decitabine and identifies a potential biomarker that could indicate a patient's stage of cancer and response to treatment. A team led by Joseph Irudayaraj, professor of agricultural and biological engineering, showed that decitabine combats some of the effects of cancer by taking the place of the nucleotide cytosine at specific locations on a replicating DNA strand. By mimicking cytosine, the drug helps "tame" cancerous cells by turning on tumor suppressor genes ...

The immune-boosting properties of breast milk have long been known. Now a team of scientists led by Johns Hopkins pediatric surgeon-in-chief David Hackam, M.D., Ph.D., says experiments in mice reveal how breast milk works to ward off the development of necrotizing enterocolitis (NEC), a devastating intestinal disorder that affects 12 percent of premature babies and claims the lives of one in four of those who have it. If affirmed in human studies, the experiments could pave the way to new preventive approaches to stave off NEC in premature babies and spark the development ...

Over the past few years, extracellular vesicles, or membrane sacs secreted from cells, have emerged as important mediators by which cells communicate with their surroundings to regulate a diverse range of biological processes. In addition, specialized roles for extracellular vesicles are beginning to be recognized in various diseases including cancer, infectious diseases and neurodegenerative disorders. Moreover, engineered extracellular vesicles are likely to have applications in drug delivery. The laboratory of Crislyn D'Souza-Schorey, Morris Pollard Professor and Chair ...

Beverages sweetened with low, medium and high amounts of high-fructose corn syrup significantly increase risk factors for cardiovascular disease, even when consumed for just two weeks by young, healthy men and women, reports a team of researchers at the University of California, Davis. The study is the first to demonstrate a direct, dose-dependent relationship between the amount of added sugar consumed in sweetened beverages and increases in specific risk factors for cardiovascular disease. The data reinforce evidence from an earlier epidemiological study showing that ...

COLUMBIA, Mo. -Due to the ever-increasing number of people using social media sites such as Facebook and Twitter, businesses and organizations, such as professional sports teams, are expanding their marketing and communication efforts to engage people with their brands through those sites. Now, Nicholas Watanabe, an assistant teaching professor at the University of Missouri, along with colleagues from MU and Louisiana State University, analyzed Major League Baseball (MLB) teams' use of Twitter to engage and increase fan interest. They found that the more individual teams ...

LEXINGTON, KY. (Apr. 22, 2015) -- It was once thought that effects of a mild head injury -- dizziness, headaches, memory problems -- were only temporary, and the brain would heal over time. However, while the long-term consequences of head trauma are not fully known, growing evidence suggests that even a mild head injury can increase the risk for later-in-life development of dementias such as Alzheimer's disease. Researchers at the University of Kentucky's Sanders-Brown Center on Aging have been attempting to understand the cascade of events following mild head injury ...

From AGU's blogs: Volcanic soundscapes reveal differences in undersea eruptions New research matching different types of underwater volcanic eruptions with their unique sound signatures could help scientists better detect and understand emissions occurring on the seafloor. From Eos.org: Is the Shale Boom Reversing Progress in Curbing Ozone Pollution? Concentrations of volatile organic compounds--precursors to ground-level ozone formation--are on the rise in areas over and downwind of a major shale oil and gas field in Texas. From AGU's journals: When the Sun ...

How aware are you of the birds that live in your neighborhood? Do you know how many different species there are? Do enjoy your local birds, or find them annoying? J. Amy Belaire of St. Edward's University, Lynne Westphal of the U.S. Forest Service, and Emily Minor and Christopher Whelan of the University of Illinois at Chicago visited urban neighborhoods in the Chicago area to answer these questions and learn more about how people see their backyard birds. Their results, published in a new paper in The Condor: Ornithological Applications, provide a fascinating look at the ...

Life as a wild baby bird can involve a lot of stress; competing with your siblings, dealing with extreme weather, and going hungry due to habitat loss are just a few examples. However, birds have an amazing capacity to overcome stresses experienced early in life and go on to reproductive success as adults, according to a new Perspective paper in The Auk: Ornithological Advances by Hugh Drummond and Sergio Ancona of the Universidad Nacional Autónoma de México. Some experiments with birds in captivity have found that increasing early-life stress through food deprivation, ...

TEMPE, Ariz. - As the search continues for Earth-size planets orbiting at just the right distance from their star, a region termed the habitable zone, the number of potentially life-supporting planets grows. In two decades we have progressed from having no extrasolar planets to having too many to search. Narrowing the list of hopefuls requires looking at extrasolar planets in a new way. Applying a nuanced approach that couples astronomy and geophysics, Arizona State University researchers report that from that long list we can cross off cosmic neighbor Tau Ceti. The ...

Scientists have found something they can't quite explain in one of the most barren environments on Earth: a bacterium whose DNA sequence contains elements usually only found in a much higher organism. Trichodesmium is a type of bacteria known as an oligotroph, meaning that it can survive in incredibly nutrient-poor regions of the ocean. In fact, it thrives there -- to the point that great blooms of the microorganism can be seen both with the naked eye and from satellites in space, earning it the name "sea sawdust" from ancient mariners. This is because Trichodesmium ...

A new type of graphene aerogel will make for better energy storage, sensors, nanoelectronics, catalysis and separations. Lawrence Livermore National Laboratory researchers have made graphene aerogel microlattices with an engineered architecture via a 3D printing technique known as direct ink writing. The research appears in the April 22 edition of the journal, Nature Communications. The 3D printed graphene aerogels have high surface area, excellent electrical conductivity, are lightweight, have mechanical stiffness and exhibit supercompressibility (up to 90 percent ...

Montréal, April 22, 2015 - Researchers at the IRCM led by Artur Kania, PhD, uncovered the critical role in pain processing of a gene associated with a rare disease. Their breakthrough, published in The Journal of Neuroscience, paves the way for a better understanding of chronic pain conditions. Dr. Kania's team studies the way neural circuits transform harmful stimuli (such as cold, heat, and pinch) into the perception of pain. More precisely, they examined the gene Lmx1b and its involvement in pain processing. Mutations in this gene also cause a rare human disease ...

PHILADELPHIA - In the first major study to examine the use of a computer-assisted, photo-driven differential diagnosis generator for skin conditions, researchers at the Perelman School of Medicine at the University of Pennsylvania found physicians routinely used the tool, without an increase in calling for inpatient dermatology consultations. The software diagnostic tool, VisualDx, aids in diagnosing dermatologic conditions by allowing physicians to enter information such as the type and location of a rash, and associated symptoms such as pain or itching, and then generating ...

SAN FRANCISCO--It may seem unlikely that a large earthquake would take place hundreds of kilometers away from a tectonic plate boundary, in areas with low levels of strain on the crust from tectonic motion. But major earthquakes such as the Mw 7.9 2008 Chengdu quake in China and New Zealand's 2011 Mw 6.3 quake have shown that large earthquakes do occur and can cause significant infrastructure damage and loss of life. So what should seismologists look for if they want to identify where an earthquake might happen despite the absence of historical seismic activity? Roger ...

COLUMBUS, Ohio - Researchers have uncovered the first evidence of a genetic link between prodigy and autism. The scientists found that child prodigies in their sample share some of the same genetic variations with people who have autism. These shared genetic markers occur on chromosome 1, according to the researchers from The Ohio State University and Nationwide Children's Hospital in Columbus. The findings confirm a hypothesis made by Joanne Ruthsatz, co-author of the study and assistant professor of psychology at Ohio State's Mansfield campus. In a previous study, ...

WASHINGTON - Vehicle cost, current battery technology, and inadequate consumer knowledge are some of the barriers preventing widespread adoption of plug-in electric vehicles, says a new congressionally mandated report from the National Research Council. Developing less expensive, better performing batteries is essential to reducing overall vehicle cost, and a market strategy is needed to create awareness and overcome customer uncertainty. The report recommends a range of incentives that the federal government can offer to address these and other barriers. The report ...