Some heparin-allergic patients could have urgent heart surgery sooner with combination of appropriate blood screenings and therapeutic plasma exchange
2014-11-18
Hamilton, ON (Nov. 18, 2014) - McMaster University researchers have found new evidence that suggests patients with a history of adverse reaction to the blood thinner heparin may be ready for urgent heart surgery sooner with a combination of appropriate blood screenings and therapeutic plasma exchange.
The study was published online today in Blood, the journal of the American Society of Hematology. The lead author is Dr. Theodore Warkentin, a professor in the Department of Medicine's Division of Hematology and Thromboembolism and the Department of Pathology and Molecular ...
High-fructose diet in adolescence may exacerbate depressive-like behavior
2014-11-18
The consumption of a diet high in fructose throughout adolescence can worsen depressive- and anxiety-like behavior and alter how the brain responds to stress, according to new animal research scheduled for presentation at Neuroscience 2014, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.
"Our results offer new insights into the ways in which diet can alter brain health and may lead to important implications for adolescent nutrition and development," said lead author Constance Harrell of ...
Lumosity presents 99,022-participant study on learning rates at Neuroscience 2014
2014-11-18
Washington, D.C. - November 18, 2014 - Lumosity is presenting new research today at the 2014 Society for Neuroscience conference on how altering cognitive task parameters affects learning rates. The study, titled "Optimizing Cognitive Task Designs to Improve Learning Rates in a Large Online Population," analyzed game play performance from 99,022 participants, and found that participants operating closer to their performance threshold earlier in their experience with a cognitive task tend to have faster learning rates - especially at higher levels of difficulty.
"By looking ...
Pioneering anti-clotting medication halves stent blockage in heart attack patients
2014-11-18
Ticagrelor halves risks of stents blocking with blood clots
Study of 18,000 patients shows cost-effective drug could prevent premature deaths
Reduces the risk of patients needing repeat operations
Treating heart attack patients with ticagrelor reduces the risk of stents blocking with blood clots according to a ground breaking new study conducted by researchers from the University of Sheffield.
The new findings confirm that treating heart attack patients with the pioneering drug ticagrelor, instead of the previous standard treatment clopidogrel, could halve the risks ...
Salamanders are a more abundant food source in forest ecosystems than previously thought
2014-11-18
COLUMBIA, Mo. - In the 1970s, ecologists published results from one of the first whole-forest ecosystem studies ever conducted in Hubbard Brook, New Hampshire. In the paper, scientists reported that salamanders represent one of the largest sources of biomass, or food, of all vertebrates in the forest landscape. Now, using new sampling and statistical techniques not available during the past study, researchers at the University of Missouri have estimated that the population of salamanders in forested regions of the Missouri Ozarks are 2-4 times higher than originally thought, ...
New data suggest little benefit of adding heart valve repair to bypass surgery in patients with coronary heart disease
2014-11-18
NEW YORK (November 18, 2014) - The addition of mitral valve (MV) repair (a valve of the heart) to coronary artery bypass grafting (CABG), a type of open-heart surgery, did not result in significant benefit to the patient and was associated with increased risk of neurological events. Therefore, the routine addition of MV repair to CABG in patients with moderate IMR did not demonstrate a clinically meaningful advantage.
The Cardiothoracic Surgical Trials Network (CTSN) is reporting results for the first time from a clinical trial of patients who have a complication of ...
Pain from rejection and physical pain may not be so similar after all
2014-11-18
Over the last decade, neuroscientists have largely come to believe that physical pain and social pain are processed by the brain in the same way. But a new study led by the University of Colorado shows that the two kinds of pain actually use distinct neural circuits, a finding that could lead to more targeted treatments and a better understanding of how the two kinds of pain interact.
For the study, published in the journal Nature Communications, the researchers used a technique recently borrowed from the computer science field by neuroscientists--multivariate pattern ...
Field-emission plug-and-play solution for microwave electron guns
2014-11-18
WASHINGTON D.C., November 18, 2014 - On a quest to design an alternative to the two complex approaches currently used to produce electrons within microwave electron guns, a team of researchers from Euclid TechLabs and Argonne National Laboratory's Center for Nanoscale Materials have demonstrated a plug-and-play solution capable of operating in this high-electric-field environment with a high-quality electron beam.
Unfamiliar with microwave electron guns? Perhaps best known within the realm of X-ray sources, microwave electron guns provide a higher current and much higher ...
New computational model could design medications like chemotherapy with fewer side effects
2014-11-18
Medications, such as chemotherapy, are often limited by their tendency to be detrimental to healthy cells as an unintended side effect. Now research in the November 18th issue of Cell Press's Biophysical Journal offers a new computational model that can help investigators design ways to direct drugs to their specific targets.
A major problem with many cancer drugs is the harmful effects they can have on normal cells. Similarly, treatments for a variety of other diseases can have side effects by acting on cells that are not meant to be targeted. Researchers have tried ...
Mother's soothing presence makes pain go away -- and changes gene activity in infant brain
2014-11-18
A mother's "TLC" not only can help soothe pain in infants, but it may also impact early brain development by altering gene activity in a part of the brain involved in emotions, according to new study from NYU Langone Medical Center.
By carefully analyzing what genes were active in infant rat brains when the mother was present or not present, the NYU researchers found that several hundred genes were more, or less, active in rat infants experiencing pain than in those that were not. With their mothers present, however, fewer than 100 genes were similarly expressed.
According ...
Computer model sets new precedent in drug discovery
2014-11-18
(BOSTON) - A major challenge faced by the pharmaceutical industry has been how to rationally design and select protein molecules to create effective biologic drug therapies while reducing unintended side effects - a challenge that has largely been addressed through costly guess-and-check experiments. Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University offer a new approach, in a study published today in Biophysical Journal.
"I believe that biology is the technology of this century," said the study's senior author and Wyss Institute ...
Using science to open way to 'blue economy'
2014-11-18
STANFORD, CA Today, scientists at the Natural Capital Project share new science and open source software that can calculate risk to coastal and marine ecosystems. These novel tools, described in the journal Environmental Research Letters, were used to design the first integrated coastal zone management plan for the Caribbean country of Belize.
Conducted with the Coastal Zone Management Authority and Institute in Belize and the World Wildlife Fund, the study offers a comprehensive explanation of the process used to calculate risk of habitat degradation in marine spatial ...
Two sensors in one
2014-11-18
CAMBRIDGE, MA -- MIT chemists have developed new nanoparticles that can simultaneously perform magnetic resonance imaging (MRI) and fluorescent imaging in living animals. Such particles could help scientists to track specific molecules produced in the body, monitor a tumor's environment, or determine whether drugs have successfully reached their targets.
In a paper appearing this week in Nature Communications, the researchers demonstrate the use of the particles, which carry distinct sensors for fluorescence and MRI, to track vitamin C in mice. Wherever there is a high ...
Virulent bacteria affecting oysters found to be a case of mistaken identity
2014-11-18
CORVALLIS, Ore. - The bacteria that helped cause the near-ruin of two large oyster hatcheries in the Pacific Northwest have been mistakenly identified for years, researchers say in a recent report.
In addition, the study shows that the bacteria now believed to have participated in that problem are even more widespread and deadly than the previous suspect.
Although the hatchery industry has largely recovered, primarily by better control of ocean water acidity that was also part of the problem, the bacterial pathogens remain a significant concern for wild oysters along ...
Scientists identify a rise in life-threatening heart infection
2014-11-18
Findings play important role in understanding impact of oral health on heart
35 extra cases of serious heart infection every month in the UK
Prescription of antibiotic prophylaxis has fallen by 89 per cent
Scientists at the University of Sheffield have identified a significant rise in the number of people diagnosed with a serious heart infection alongside a large fall in the prescribing of antibiotic prophylaxis to dental patients.
The pioneering study is the largest and most comprehensive to be conducted with regards to the National Institute for Health and Care ...
Big data study identifies new potential target coating for drug-eluting stents
2014-11-18
NEW YORK, NY - November 17, 2014 - A new study has identified an FDA approved cancer drug, crizotinib, as a possible new coating for drug-eluting stents. Researchers found that crizotinib in mice helped prevent the narrowing of blood vessels after stenting without affecting the blood vessel lining. Results of this study were published today in the Journal of Clinical Investigation.
To find a more effective drug to use on stents, researchers used a computational biology or "big data" approach to better understand the genetic pathways of re-narrowing that occurs in stented ...
Taking antibiotics during pregnancy increases risk for child becoming obese
2014-11-18
November 18, 2014 -- A study just released by Columbia University's Mailman School of Public Health found that children who were exposed to antibiotics in the second or third trimester of pregnancy had a higher risk of childhood obesity at age 7. The research also showed that for mothers who delivered their babies by a Caesarean section, whether elective or non-elective, there was a higher risk for obesity in their offspring. Study findings are published online in the International Journal of Obesity.
Although previous studies have shown that antibiotics administered early ...
High earthquake danger in Tianjin, China
2014-11-18
Boulder, Colo., USA - With a population of 11 million and located about 100 km from Beijing (22 million people) and Tangshan (7 million people), Tianjin lies on top of the Tangshan-Hejian-Cixian fault that has been the site of 15 devastating earthquakes in the past 1,000 years. An example of the disastrous events is the 1976 magnitude 7.6 Tangshan Earthquake, which killed a quarter million people.
To assess future seismic hazards along the fault, scientists from the University of California at Los Angeles (UCLA) and the Chinese Earthquake Administration (CEA) have reconstructed, ...
Were Neanderthals a sub-species of modern humans? New research says no
2014-11-18
In an extensive, multi-institution study led by SUNY Downstate Medical Center, researchers have identified new evidence supporting the growing belief that Neanderthals were a distinct species separate from modern humans (Homo sapiens), and not a subspecies of modern humans.
The study looked at the entire nasal complex of Neanderthals and involved researchers with diverse academic backgrounds. Supported by funding from the National Science Foundation and the National Institutes of Health, the research also indicates that the Neanderthal nasal complex was not adaptively ...
New model clarifies photoexcited thin-film lattice dynamics
2014-11-18
WASHINGTON D.C., November 18, 2014 -- A research team from Germany developed an analytical model to describe the structural dynamics of photoexcited thin films and verified it by ultrafast X-ray diffraction.
Lattice dynamics, atomic movements in a crystal structure, can influence the physical and chemical properties of a material. The phenomenon can be directly studied using ultrafast X-ray diffraction, in which femtosecond X-ray pulses take snapshots of the atomic positions in a crystal by interacting with the structure at the core electronic level.
However, no comprehensive ...
New treatment for Marfan syndrome shows promise
2014-11-18
An investigational treatment for Marfan syndrome is as effective as the standard therapy at slowing enlargement of the aorta, the large artery of the heart that delivers blood to the body, new research shows. The findings indicate a second treatment option for Marfan patients, who are at high risk of sudden death from tears in the aorta.
The results are being presented Nov. 18 at the American Heart Association's annual meeting in Chicago and will appear online the same day in the New England Journal of Medicine.
"For years, standard medical therapy for Marfan syndrome ...
A bird's-eye view of the protein universe
2014-11-18
Each cell contains thousands of proteins, each one of which bears a unique signature. All proteins, distinct in shape and function, are built from the same amino acid strings. Many proteins are vital, as evidenced by the plethora of diseases linked to their absence or malfunction. But how exactly did proteins first come to be? Do they all share a single common ancestor? Or did proteins evolve from many different origins?
Forming a global picture of the protein universe is crucial to addressing these and other important questions, but it's nearly impossible to do. Such ...
Shift in gut bacteria observed in fiber supplement study may offer good news for weight loss
2014-11-18
URBANA, Ill. - Most Americans don't get the daily recommended amount of fiber in their diet, though research has shown that dietary fiber can cause a shift in the gut toward beneficial bacteria, reducing the risk of colon cancer, type 2 diabetes, and other diseases. A new study from the University of Illinois shows that two specific functional fibers may also have the potential to assist in weight loss when made part of a long-term, daily diet.
Kelly Swanson, a U of I professor of nutrition, and his team had previously been able to see a "snapshot" of what bacteria were ...
NASA sees Tropical Cyclone Adjali develop a tail
2014-11-18
When NASA's Terra satellite passed over the Southern Indian Ocean, the MODIS instrument aboard captured a picture of Tropical Cyclone Adjali that showed it developed a "tail," which is actually band of thunderstorms extending south of the center.
The Moderate Resolution Imaging Spectroradiometer, or MODIS instrument that flies aboard NASA's Terra satellite took a visible picture of Tropical Storm Adjali on Nov. 18 at 05:35 UTC (12:35 a.m. EST). The MODIS image showed a concentration of strong storms around the center of Adjali's circulation and a band of thunderstorms ...
Musicians show advantages in long-term memory, UT Arlington research says
2014-11-18
A peek inside the brains of professional musicians has given University of Texas at Arlington psychology researchers what may be the first links between music expertise and advantages in long-term memory.
Heekyeong Park, assistant professor of psychology, and graduate student James Schaeffer used electroencephalography (EEG) technology to measure electrical activity of neurons in the brains of 14 musicians and 15 non-musicians and noted processing differences in the frontal and parietal lobe responses. The team will present initial results of their new research Tuesday ...
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