DURHAM, N.C. - Most of the revenues extracted from use of the world's oceans is concentrated among 100 transnational corporations, which have been identified for the first time by researchers at Duke University and the Stockholm Resilience Centre at Stockholm University. Dubbed the "Ocean 100," these "ocean economy" companies collectively generated $1.1 trillion in revenues in 2018, according to research published Wednesday in the journal Science Advances. If the group were a country, it would have the world's 16th-largest economy, roughly equivalent to the gross domestic product (GDP) of Mexico. "Now that we know who some of the biggest beneficiaries from the ocean economy are, this can help improve transparency relating to sustainability and ocean ...

Schools of fish exhibit complex, synchronized behaviors that help them find food, migrate and evade predators. No one fish or team of fish coordinates these movements nor do fish communicate with each other about what to do next. Rather, these collective behaviors emerge from so-called implicit coordination -- individual fish making decisions based on what they see their neighbors doing. This type of decentralized, autonomous self-organization and coordination has long fascinated scientists, especially in the field of robotics. Now, a team of researchers at the Harvard John A. Paulson School of Engineering and ...

Philadelphia, January 13, 2021--Researchers at Children's Hospital of Philadelphia and the School of Engineering and Applied Science at the University of Pennsylvania have identified ionizable lipid nanoparticles that could be used to deliver mRNA as part of fetal therapy. The proof-of-concept study, published today in Science Advances, engineered and screened a number of lipid nanoparticle formulations for targeting mouse fetal organs and has laid the groundwork for testing potential therapies to treat genetic diseases before birth. "This is an important first step in identifying nonviral mediated approaches for delivering cutting-edge therapies before birth," said co-senior author William H. Peranteau, MD, an attending surgeon in the Division of ...

PHILADELPHIA -- (Jan. 13, 2021) -- Scientists at The Wistar Institute discovered that Early Growth Response 1 (EGR1), a protein that turns on and off specific genes during blood cell development, inhibits expression of pro-inflammatory genes in macrophages. As part of their function to protect the body against pathogens, macrophages play a major role in initiation, maintenance, and resolution of inflammation. The discovery expands the understanding of how macrophages are set off and deactivated in the inflammatory process, which is critical in many normal and pathological conditions. These findings were published online in the journal Science Advances. "By deepening the understanding of the role of EGR1, we ...

COLUMBUS, Ohio - While we wait for our turn to get vaccinated against SARS-CoV-2, we could - and probably should - use the time to make sure we bring our healthiest emotional and physical selves to the treatment, a new review of previous research suggests. Ohio State University researchers reviewed 49 vaccine studies in humans dating back 30 years that document how stress, depression and poor health behaviors can negatively affect the body's immune response to vaccination, and how improving health factors can enhance that response. The impaired immune responses tended to fall into three categories - interference with the ...

Skoltech researchers have found a way to use chemical sensors and computer vision to determine when grilled chicken is cooked just right. These tools can help restaurants monitor and automate cooking processes in their kitchens, and perhaps one day even end up in your 'smart' oven. The paper detailing this research results, supported by a Russian Science Foundation grant, was published in the journal Food Chemistry. How do you tell that chicken breast on your grill is ready for your plate? You probably look at it closely and smell it to make sure it is done the way you like it. However, if you are a restaurant chef or head cook at a huge industrial ...

Scientists tame photon-magnon interaction. Working with theorists in the University of Chicago's Pritzker School of Molecular Engineering, researchers in the U.S. Department of Energy's (DOE) Argonne National Laboratory have achieved a scientific control that is a first of its kind. They demonstrated a novel approach that allows real-time control of the interactions between microwave photons and magnons, potentially leading to advances in electronic devices and quantum signal processing. Microwave photons are elementary particles forming the electromagnetic waves that we use for wireless communications. On the other hand, magnons are the elementary particles forming what scientists call "spin waves" -- wave-like disturbances in ...

In a study in mice and human cells, Johns Hopkins Medicine researchers say that they have developed a tiny, yet effective method for preventing premature birth. The vaginally-delivered treatment contains nanosized (billionth of a meter) particles of drugs that easily penetrate the vaginal wall to reach the uterine muscles and prevent them from contracting. If proven effective in humans, the treatment could be one of the only clinical options available to prevent preterm labor. The FDA has recommended removing Makena (17-hydroxyprogesterone caproate), the only approved medicine for this purpose, from the market. The study was published Jan. 13 in Science Translational Medicine. There ...

A group of scientists led by the American Museum of Natural History and Bat Conservation International have discovered a new species of a striking orange and black bat in a mountain range in West Africa. The species, which the researchers expect is likely critically endangered, underscores the importance of sub-Saharan "sky islands" to bat diversity. The species is described today in the journal American Museum Novitates. "In an age of extinction, a discovery like this offers a glimmer of hope," said Winifred Frick, chief scientist at Bat Conservation International and ...

With the impact of climate change increasing by the day, scientists are studying the ways in which human behavior contributes to the damage. A recent study at Walla Walla University, by a collaboration of researchers from Walla Walla University and La Sierra University, examined the effects of acidic water on octopuses, potentially bringing new insight into both how our activities impact the world around us, and the way that world is adapting in response. The study, "Impact of Short- and Long-Term Exposure to Elevated Seawater PCO2 on Metabolic Rate ...

The human organism requires a variety of small molecules, such as sugars or fats, in order to function properly. The composition of these so-called metabolites and their interaction - the metabolism - varies from person to person and is dependent not only on external influences, such as nutrition, but also to a significant extent on natural variations in our genetic make-up. In an international study, scientists from the Berlin Institute of Health (BIH) and Charité - Universitätsmedizin Berlin joined forces with colleagues from the United Kingdom, Australia and the United States and discovered hundreds ...

A new study from UBC researchers suggests a strong correlation between following the MIND and Mediterranean diets and later onset of Parkinson's disease (PD). While researchers have long known of neuroprotective effects of the MIND diet for diseases like Alzheimer's and dementia, this study is the first to suggest a link between this diet and brain health for Parkinson's disease (PD). The MIND diet combines aspects of two very popular diets, the Mediterranean diet and the Dietary Approaches to Stop Hypertension (DASH) diet. "The study shows individuals with Parkinson's disease have a significantly later age of onset if their eating pattern closely aligns with the Mediterranean-type diet. The difference shown in the study was up to 17 years later in women and eight years later ...

There are things in life that can be predicted reasonably well. The tides rise and fall. The moon waxes and wanes. A billiard ball bounces around a table according to orderly geometry. And then there are things that defy easy prediction: The hurricane that changes direction without warning. The splashing of water in a fountain. The graceful disorder of branches growing from a tree. These phenomena and others like them can be described as chaotic systems, and are notable for exhibiting behavior that is predictable at first, but grows increasingly random with time. Because of the large role that chaotic systems play in the world around us, scientists and mathematicians have long sought to better understand them. Now, Caltech's Lihong Wang, the Bren Professor in the Andrew and ...

CORVALLIS, Ore. -- A recent study from Oregon State University found that after Oregon expanded Medicaid in 2014, more women were able to receive insurance coverage for abortion services, rather than paying out of pocket. In analyzing Medicaid claims data and other medical records, researchers found that the Medicaid-financed share of total abortions increased each of the first three years following the state's Medicaid expansion. The incidence of Medicaid-financed abortions increased 18% in 2014, then 7% each in 2015 and 2016. The total number of abortions in the state did not rise; rather, the expansion shifted who paid for them. "According to the literature, there was a 1% decline in the abortion rate in Oregon between 2014 and 2017. During the pre-expansion ...

As marijuana outlets open after the drug is legalized, the density of those recreational retailers is associated with more use and a greater intensity of use among young adults, according to a new RAND Corporation study. The study is among the first to examine associations between the density of marijuana outlets and marijuana use over time, and is the first to include unlicensed dispensaries in such an analysis. Studying young adults in Los Angeles County the year before and the year after marijuana was available for recreational purchase in ...

TROY, N.Y. -- Blood sample analysis showed that, two to five years after they gave birth, mothers of children with autism spectrum disorder (ASD) had several significantly different metabolite levels compared to mothers of typically developing children. That's according to new research recently published in BMC Pediatrics by a multidisciplinary team from Rensselaer Polytechnic Institute, Arizona State University, and the Mayo Clinic. Researchers analyzed blood samples from 30 mothers whose young children had been diagnosed with ASD and 29 mothers of typically developing children. At the time that the samples were taken, the women's children were between 2 and 5 years old. The team found differences in several metabolite levels between the two groups of mothers. ...

Research led by the University of Wyoming shows that physical weathering is far more important than previously recognized in the breakdown of rock in mountain landscapes. Because it is difficult to measure, physical weathering has commonly been assumed to be negligible in previous studies. Cliff Riebe, a professor in UW's Department of Geology and Geophysics, headed a research group that discovered that climate and erosion rates strongly regulate the relative importance of subsurface physical and chemical weathering of saprolite, the zone of weathered rock that retains the relative positions of mineral grains of the parent bedrock and lies between ...

A compound developed at Oregon Health & Science University appears to protect nerve fibers and the fatty sheath, called myelin, that covers nerve cells in the brain and spinal cord. The discovery, published in the Journal of Neuroimmunology, could be important in treating or preventing the progression of multiple sclerosis and other central nervous system disorders. The new research in a mouse model advances earlier work to develop the compound - known as sobetirome - that has already showed promise in stimulating the repair of myelin. "Sobetirome and related drugs are effective at stimulating myelin repair after damage has occurred. Our new findings now suggest that these drugs could also prove ...

Earth gets blasted by mild short gamma-ray bursts (GRBs) most days. But sometimes a giant flare like GRB 200415A arrives at our galaxy, sweeping along energy that dwarfs our sun. In fact, the most powerful explosions in the universe are gamma-ray bursts. Now scientists have shown that GRB 200415A came from another possible source for short GRBs. It erupted from a very rare, powerful neutron star called a magnetar. Previous detected GRB's came from relatively far away from our home galaxy the Milky Way. But this one was from much closer to home, in cosmic terms. GRB explosions can disrupt mobile phone reception on earth, but they can also be messengers from ...

(Boston)--What percent of patients with Alzheimer's Disease (AD) currently have severe dementia? Do more people have mild disease? Or are the majority suffering with moderate dementia? A new study using data from the Framingham Heart Study (FHS) sheds light on these trends. Boston University School of Medicine researchers have found that slightly more than half (50.4 percent) of cases are mild, just under one-third (30.3 percent) of cases are moderate and 19.3 percent are severe cases. Among all participants with mild cognitive impairment (MCI) and AD, the pooled percentage was 45.2 percent for the combined group of mild AD dementia and MCI that later ...

In 2007, an increase in world food prices led to a global rush for land in the form of land grabs or large-scale land acquisitions. Over the last two decades, such acquisitions have resulted in millions of hectares of land changing hands in developing nations. Although such changeover can increase the cultivation of crops needed to feed the world's growing population and spark new agricultural practices and technologies, it can also lead to environmental degradation, increased carbon emissions and threats to the livelihoods of smallholder farmers. The socioeconomic ...

Financial responsibility means managing money in a relatively sensible way by minimizing superfluous or unnecessary spending. But according to new research from the University of Notre Dame, people think they are more financially responsible than they actually are. Even when people consistently spend their money superfluously, they still believe that they manage their money in a responsible fashion, according to " END ...

New Rochelle, NY, January 13, 2021--Aggressive video games are not a risk factor for mental health problems, according to a new study of more than 3,000 youth. This study is part of a special issue on the effects of violent video games published in the peer-reviewed journal Cyberpsychology, Behavior, and Social Networking. Click here to read the issue now. Christopher Ferguson, PhD, Stetson University, and C.K. John Wang, PhD, Nanyang Technological University, examined whether early exposure to aggressive games was predictive of anxiety depression, somatic symptoms, or ...

Apart from black holes, magnetars may be the most extreme stars in the universe. With a diameter less than the length of Manhattan, they pack more mass than that of our sun, wield the largest magnetic field of any known object -- more than 10 trillion times stronger than a refrigerator magnet -- and spin on their axes every few seconds. A type of neutron star -- the remnant of a supernova explosion -- magnetars are so highly magnetized that even modest disturbances in the magnetic field can cause bursts of X-rays that last sporadically for weeks or months. These exotic, compact stars are also thought to be the source of some types of short gamma ray bursts (GRBs): bright flashes of highly energetic radiation that have ...

Primary amoebic meningoencephalitis (PAM), a deadly disease caused by the "brain-eating amoeba" Naegleria fowleri, is becoming more common in some areas of the world, and it has no effective treatment. Now, researchers reporting in ACS Chemical Neuroscience have found that a compound isolated from the leaves of a traditional medicinal plant, Inula viscosa or "false yellowhead," kills the amoebae by causing them to commit cell suicide in lab studies, which could lead to new treatments. PAM, characterized by headache, fever, vomiting, hallucinations and seizures, is almost always fatal within a couple of weeks of developing symptoms. Although the disease, which is usually contracted ...