Although Ibuprofen and oral morphine both provide effective pain relief for children with broken limbs, ibuprofen is the recommended choice because of adverse events associated with oral morphine, according to a randomized trial published in CMAJ (Canadian Medical Association Journal) Fractures make up between 10% and 25% of all children's injuries, and the most severe pain is felt during the first 48 hours after the injury. Because of concerns about the safety of codeine for children, there is limited choice for medications to relieve pain for these patients. "Evidence ...

A new Canadian guideline recommends that the prostate-specific antigen (PSA) test should not be used to screen for prostate cancer based on evidence that shows an increased risk of harm and uncertain benefits. The guideline is published in CMAJ (Canadian Medical Association Journal) "Some people believe men should be screened for prostate cancer with the PSA test but the evidence indicates otherwise," states Dr. Neil Bell, member of the Canadian Task Force on Preventive Health Care and chair of the prostate cancer guideline working group. "These recommendations balance ...

The team of researchers, led by Dr Rafael Carazo Salas from the Department of Genetics, combined high-resolution 3D confocal microscopy and computer-automated analysis of the images to survey the fission yeast genome with respect to three key cellular processes simultaneously: cell shape, microtubule organisation and cell cycle progression. Microtubules are small, tube-like structures which help cells divide and give them their structure. Of the 262 genes whose functions the team report in a study published today in the journal Developmental Cell, two-thirds are linked ...

ity of Industry, CA – October 28, 2014 – A new randomized controlled trial (RCT) of post-menopausal women demonstrates that a proprietary blend of collagen and calcium, KoACT®, was far superior to calcium and vitamin D in slowing down the leaching of calcium from bones and rebuilding new bone strength. An Abstract of the article appears on PubMed at: http://www.ncbi.nlm.nih.gov/pubmed/25314004, ahead of print in The Journal of Medicinal Food. The research was conducted by Bahram H. Arjmandi, PhD, RDN, who is currently Margaret A. Sitton Named Professor ...

WASHINGTON (Oct. 27, 2014) — Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. These flatworms, including tapeworms that cause hydatid diseases and neurocysticercosis, liver flukes, and blood flukes (schistosomes), infect more than 300 million people and cause approximately four million disability-adjusted life years lost due to chronic illness and death each year. Paul Brindley, Ph.D., professor of microbiology, immunology, and tropical medicine, and scientific director of the Research Center for Neglected ...

In the on-going effort to develop advanced biofuels as a clean, green and sustainable source of liquid transportation fuels, researchers at the U.S. Department of Energy (DOE)'s Joint BioEnergy Institute (JBEI) have identified microbial genes that can improve both the tolerance and the production of biogasoline in engineered strains of Escherichia coli. Aindrila Mukhopadhyay, a chemist who directs the host engineering program for JBEI's Fuels Synthesis Division, led a study in which transcriptomic data and a synthetic metabolic pathway were used to identify several genes ...

NASA's Terra satellite spotted a "zombie" tropical storm as Halloween week kicks off. Tropical Depression 9 made landfall in Mexico's Yucatan Peninsula late last week and lingered as a remnant low pressure area on Saturday and Sunday, Oct. 25 and 26. Satellite data revealed that those remnants had reformed quickly and jumped up to tropical storm status, where it became "zombie" storm named Tropical Storm Hanna off the coast of Nicaragua. NASA's Terra satellite spotted strong thunderstorms around the zombie storm's center as it passed overhead. At 9:30 a.m. EDT on Oct. ...

Using ultrasound technology to visualize the tongue's shape and movement can help children with difficulty pronouncing "r" sounds, according to a small study by NYU's Steinhardt School of Culture, Education, and Human Development and Montclair State University. The ultrasound intervention was effective when individuals were allowed to make different shapes with their tongue in order to produce the "r" sound, rather than being instructed to make a specific shape. The findings appear online in the Journal of Speech, Language, and Hearing Research. The "r" sound is one ...

Difficulty in conceiving a child is a major challenge for one in seven heterosexual couples in America, especially for those over the age of 35. Now a new discovery by researchers at Tel Aviv University and Chaim Sheba Medical Center at Tel Hashomer could boost the chances of conception in women undergoing in vitro fertilization (IVF) treatments. Their new research reveals a linkage between the genes of the innate immune system — immunity with which human beings are born, rather than immunity they acquire during their lives — and ovarian longevity. The study, ...

Rice University researchers have delivered a scientific one-two punch with a pair of papers that detail how synthetic collagen fibers self-assemble via their sticky ends. Collagen is the most common protein in mammals, a major component of bone and the fibrous tissues that support cells and hold organs together. Discovering its secrets may lead to better synthetic collagen for tissue engineering and cosmetic and reconstructive medicine. The Rice lab of Jeffrey Hartgerink has been studying synthetic collagen for a decade, teasing out the details of how it starts as three ...

The Asian tiger mosquito (Aedes albopictus), which is native to Southeast Asia, was spotted in Houston in 1985. By 1986 it had reached St. Louis and Jacksonville, Fla. Today it can be found in all of the southern states and as far north as Maine. An aggressive daytime biter, Ae. albopictus has an affinity for humans and is also a vector for human disease, said Kim Medley, PhD, interim director of the Tyson Research Center at Washington University in St. Louis. The mosquito arrived in the U.S. in a shipment of used tires from Japan. Ae. albopictus lays eggs that can ...

Adélie penguins are an indigenous species of the West Antarctic Peninsula (WAP), one of the most rapidly warming areas on Earth. Since 1950, the average annual temperature in the Antarctic Peninsula has increased 2 degrees Celsius on average, and 6 degrees Celsius during winter. As the WAP climate warms, it is changing from a dry, polar system to a warmer, sub-polar system with more rain. University of Delaware oceanographers recently reported a connection between local weather conditions and the weight of Adélie penguin chicks in an article in Marine Ecology ...

The price tag for informal caregiving of elderly people by friends and relatives in the United States comes to $522 billion a year, according to a new RAND Corporation study. Replacing that care with unskilled paid care at minimum wage would cost $221 billion, while replacing it with skilled nursing care would cost $642 billion annually. The study, published online by the journal Health Services Research, improves on earlier estimates about the value of informal caregiving by making use of the 2011 and 2012 American Time Use Survey, a new and unique database, to provide ...

A study from Massachusetts General Hospital (MGH) investigators has identified for the first time changes in the metabolic activity of a key brain region in patients successfully treated for depression with psychodynamic psychotherapy, suggesting a mechanism of action behind one of the most historically important and widely practiced forms of therapy. They also found evidence that pretreatment metabolism in a different brain structure might predict which patients are likely to respond to that form of therapy. Their report will appear in the journal Psychotherapy and Psychosomatics ...

Do blood vessels that feed tumors differ from other blood vessels? Fourteen years ago, experiments designed to answer that question led to the discovery of several genes that are more active in tumor-associated blood vessels than in normal blood vessels. New research now reveals the normal function of one of those genes and suggests it could be a good target for anticancer drug therapy. A summary of the research appears in the journal Developmental Cell on Oct. 27. The mystery of the gene, TEM5, began in 2000 with research conducted by Brad St. Croix, Ph.D., working ...

For decades, honeybees have been battling a deadly disease that kills off their babies (larvae) and leads to hive collapse. It's called American Foulbrood and its effects are so devastating and infectious, it often requires infected hives to be burned to the ground. Treating Foulbrood is complicated because the disease can evolve to resist antibiotics and other chemical treatments. Losing entire hives not only disrupts the honey industry, but reduces the number of bees for pollinating plants. Now researchers at BYU have produced a natural way to eliminate the scourge, ...

Parents can learn to use a scientifically validated autism therapy with their own children by taking a short series of group classes, a new study by researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford has found. The therapy helped children improve their language skills, an area of deficiency in autism, according to the study, which will be published Oct. 27 in the Journal of Child Psychology and Psychiatry. The study is the first randomized, controlled trial to test whether group classes are a good way to train parents ...

You don't always need GPS, a map or a compass to find the right way. What demands a tremendous amount of computational power from today's navigation computers can also be achieved by taking advantage of the laws of physical chemistry and practicing so-called "chemical computing". The trick works as follows: A gel mixed with acid is applied at the exit of a labyrinth – i.e. the destination – filled with alkaline liquid. Within a shorttime, the acid spreads through the alkaline maze, although the majority of it remains together with the gel at the exit. When an ...

WASHINGTON, Oct. 27, 2014 — It's a spooky question, but it doesn't have to be: What happens when you die? Even after you depart, there's a lot of chemistry that still goes on inside you. Reactions teamed up with mortician Caitlin Doughty, author of the new book "Smoke Gets in your Eyes, and Other Lessons from the Crematory" to demystify death and talk about exactly what happens to the body postmortem. Check out the new episode here: http://youtu.be/BpuTLnSr_20. Subscribe to the series at Reactions YouTube, and follow us on Twitter @ACSreactions to be the first to ...

When Hurricane Sandy struck the east coast in late October 2012, the "superstorm" disrupted traffic in New York City for more than five days, but the evacuation proceeded relatively efficiently with only minor delays, according to transportation researchers at the University of Illinois. The largest Atlantic hurricane on record, Hurricane Sandy offered a chance for researchers at the University of Illinois at Urbana-Champaign to try out a new computational method they developed that promises to help municipalities quantify the resilience of their transportation systems ...

WASHINGTON, DC—The American Academy of Pediatrics (AAP), American Academy of Family Physicians (AAFP), American College of Physicians (ACP) and American Osteopathic Association (AOA) convene today in Washington, DC to urge Congress to extend current-law payment parity for primary care and immunization services under Medicaid for at least two years. Absent congressional action, federal support for this policy runs out at the end of the year. Collectively representing nearly 423,000 physicians, the four groups are meeting with dozens of congressional offices on Capitol ...

New Rochelle, NY, October 27, 2014—More than half of women with children less than a year old are working, and work travel can make breastfeeding a challenge. A study of 100 U.S. airports found that few provided a suitably equipped, private lactation room, even though most described themselves as being breastfeeding friendly, as reported in Breastfeeding Medicine, the official journal of the Academy of Breastfeeding Medicine published by Mary Ann Liebert, Inc., publishers. The article is available free on the Breastfeeding Medicine website at http://online.liebertpub.com/doi/full/10.1089/bfm.2014.0112 ...

This news release is available in French. A key to aortic valve disease prevention: Lowering cholesterol early Montreal, Sunday 26, 2014 – An international research team led by the Research Institute of the McGill University Health Centre (RI-MUHC) and Lund University has provided new evidence that aortic valve disease may be preventable. Their findings show that so-called "bad" cholesterol or low-density lipoprotein-cholesterol (LDL-C) is a cause of aortic valve disease – a serious heart condition that affects around five million people in North America ...

New York | Heidelberg, 27 October 2014 Thermodiffusion, also called the Soret effect, is a mechanism by which an imposed temperature difference establishes a concentration difference within a mixture. Two studies1,2 by Belgian scientists from the Free University of Brussels, recently published in EPJE, provide a better understanding of such effects. They build on recent experimental results from the IVIDIL (Influence Vibration on Diffusion in Liquids) research project performed on the International Space Station under microgravity to avoid motion in the liquids. In the ...

Case Western Reserve University mental health researcher Joseph Galanek spent a cumulative nine months in an Oregon maximum-security prison to learn first-hand how the prison manages inmates with mental illness. What he found, through 430 hours of prison observations and interviews, is that inmates were treated humanely and security was better managed when cell block officers were trained to identify symptoms of mental illness and how to respond to them. In the 150-year-old prison, he discovered officers used their authority with flexibility and discretion within ...