About The Study: This study found a disproportionate spike in firearm homicide among children and adults older than age 30 after the onset of the COVID-19 pandemic, indicating a change in the association between age and firearm victimization risk. This trend moved the peak victimization risk from age 21 to 19, and rates for children up to age 16 were markedly elevated. These age-specific patterns were most pronounced in later post-onset years.  Corresponding Author: To contact the corresponding author, Jonathan ...

About The Study: This study found that avoidable mortality (comprising both preventable deaths related to prevention and public health and treatable deaths related to timely and effective health care treatment) has worsened across all U.S. states, while other high-income countries show improvement. The results suggest poorer mortality is driven by broad factors across the entirety of the U.S. While other countries appear to make gains in health with increases in health care spending, such an association does not exist across U.S. states, raising questions regarding U.S. health spending efficiency.  Corresponding Author: To contact the corresponding author, Irene ...

About The Study: Exclusive or longer duration of breastfeeding was associated with reduced odds of developmental delays and language or social neurodevelopmental conditions in this cohort study. These findings may guide parents, caregivers, and public health initiatives in promoting early child development. Corresponding Author: To contact the corresponding author, Inbal Goldshtein, PhD, email inbal@kinstitute.org.il. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.1540) Editor’s Note: Please see the ...

Among the many marvels of life is the cell’s ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA – its genome – and segregate it equally into two new daughter cells. To prepare the 46 chromosomes of a human cell for transport to the daughter cells during cell division, each chromosome forms a compact X-shaped structure with two rod-like copies. How the cell achieves this feat remains largely unknown. Now, for the first time, EMBL scientists have directly observed this process in high resolution under the microscope ...

After every meal, the intestines perform an action called peristalsis — moving food through their hollow interiors with coordinated contractions and relaxations of the smooth muscle. For more than a century, scientists have known that nerve cells in the gut propel the colon to move, allowing the organ to perform its life-sustaining function. But exactly how these intestinal nerve cells do their job has remained elusive. Now a new NIH-funded study led by researchers at Harvard Medical School and the Icahn School of Medicine at Mount Sinai has identified ...

A moiré pattern appears when you stack and rotate two copies of an image with regularly repeating shapes, turning simple patterns of squares or triangles into a groovy wave pattern that moves across the combined image in an optical delight.  Similarly, stacking single layers of sub-nanometer-thick semiconductor materials known as transition metal dichalcogenides (TMDs) can generate a moiré potential, and novel electronic and optoelectronic properties may emerge between the layers.  A moiré potential is a “seascape” of potential energy with regularly repeating peaks and valleys. They were previously thought to be stationary. But a team of ...

AI tools are transforming how we observe the world around us — and even the stars beyond. Recently, an international team proved that deep learning techniques and large language models can help astronomers classify stars with high accuracy and efficiency. Their study, “Deep Learning and Methods Based on Large Language Models Applied to Stellar Light Curve Classification,” was published Feb. 26 in Intelligent Computing, a Science Partner Journal. The team introduced the StarWhisper LightCurve series, a trio of AI models, and evaluated their performance ...

Background and Aims General transcription factor IIIC subunit 2 (GTF3C2) is one of the polymerase III transcription-related factors. Previous studies have revealed that GTF3C2 is involved in regulating cell proliferation. However, the role of GTF3C2 in hepatocellular carcinoma (HCC) remains unclear. This study aimed to determine its expression, biological function, and mechanism in HCC. Methods The expression of GTF3C2 in HCC and non-tumor tissues, along with its clinical significance, was investigated using public databases and clinical samples. Reverse transcription-quantitative polymerase ...

A recent article in BioScience, the journal of the American Institute of Biological Sciences, challenges conventional conservation wisdom, suggesting that protected areas such national parks and designated wilderness areas must embrace natural landscape dynamics rather than trying to preserve static conditions and landscape features. Dr. Gavin M. Jones (USDA Forest Service) and colleagues contend that current conservation models often resist natural ecosystem processes such as wildfire, leading to a "backfire effect" that makes ecosystems more vulnerable ...

WASHINGTON – A depression prevention program that has helped white youth wasn’t effective for Black youth, raising concerns about the need for more research to help racially diverse groups, according to new research published by the American Psychological Association.  “I was very surprised that we couldn’t help Black youth as much as white youth, and we don’t know why there was such a profound difference in the outcomes.” said lead researcher Patrick Pössel, Dr. rer. soc., a professor of counseling psychology ...

People convicted of federal white-collar crimes come from different social and demographic backgrounds compared to those convicted of other offenses. Typically older and from the middle class, white-collar offenders face unique challenges during reentry into society. Yet, research on how social class influences their reintegration remains scarce. A study by Florida Atlantic University, in collaboration with the University of Cincinnati, explores these challenges, focusing on how stigma, social background and emotional factors impact white-collar offenders as they transition into society ...

CAMBRIDGE, MA -- MIT engineers have devised a new way to deliver certain drugs in higher doses with less pain, by injecting them as a suspension of tiny crystals. Once under the skin, the crystals assemble into a drug “depot” that could last for months or years, eliminating the need for frequent drug injections. This approach could prove useful for delivering long-lasting contraceptives or other drugs that need to be given for extended periods of time. Because the drugs are dispersed in a suspension before injection, they can be administered through a narrow needle that is easier for patients to tolerate. “We showed that we can have very controlled, sustained delivery, ...

Life takes shape with the motion of a single cell. In response to signals from certain proteins and enzymes, a cell can start to move and shake, leading to contractions that cause it to squeeze, pinch, and eventually divide. As daughter cells follow suit down the generational line, they grow, differentiate, and ultimately arrange themselves into a fully formed organism.  Now MIT scientists have used light to control how a single cell jiggles and moves during its earliest stage of development. The team studied the motion of egg cells produced by starfish — an organism that scientists have long used as a classic model for ...

Frederic L.W.V.J. Schaper, MD, PhD, director of Epilepsy Network Mapping at the Center for Brain Circuit Therapeutics at Brigham and Women’s Hospital and an instructor of neurology at Harvard Medical School, is the senior author of a paper published in Nature Communications, “A generalized epilepsy network derived from brain abnormalities and deep brain stimulation.” How would you summarize your study for a lay audience? Generalized epilepsy has traditionally been considered a seizure of the ‘whole brain.’ However, new research has challenged this longstanding idea, since carefully targeting specific brain areas through deep brain stimulation ...

IMDEA Networks has begun its participation in DISCO6G, an innovative project that will transform next-generation mobile networks, in collaboration with UC3M, UAM, and UPM and funded by the Madrid Regional Government. Its focus on Integrated Sensing and Communication (ISAC) enables network infrastructures not only to transmit information but also to function as distributed real-time sensors. "DISCO6G represents a paradigm shift, as it turns the network into a system capable of detecting its environment while ...

SAN DIEGO, March 24, 2025 — When wildfires threaten people’s communities, human health is impacted far beyond the inferno. Residual smoke distributes on the breeze, infiltrating homes, schools and offices. To help people protect themselves and their families, researchers have developed a low-cost, durable, do-it-yourself (DIY) air cleaner that works as well as more expensive HEPA filters to clear indoor air of pollutants such as smoke and possibly limit the impact of airborne disease spread. Richard Corsi, dean of the University of California, Davis (UC Davis) College of Engineering, will present results from his ...

A technique to improve the precision of prostate cancer surgery means that almost twice as many men preserve their erectile function compared to those undergoing standard surgery, according to results from a clinical trial led by researchers from UCL and UCLH. The results of the NeuroSAFE PROOF trial, presented at the 2025 European Association of Urology (EAU) Congress in Madrid and published in The Lancet Oncology, raise the prospect of major quality of life improvements for men undergoing surgery for prostate cancer, which can often result in erectile ...

New data published by ECDC and the World Health Organization (WHO) Regional Office for Europe [1] show that with almost 39 000 reported tuberculosis cases in 2023, the 29 European Union and European Economic Area (EU/ EEA) countries continue to see increases in TB notifications. Given that young children have an increased risk of developing tuberculosis disease during the first year after infection, childhood TB serves as a marker for ongoing transmission within a community.  The new data for 2023 indicate that children and adolescents under the age of 15 accounted for ...

A new study has shown that almost all people claiming Universal Credit aren’t able to eat properly, with many never eating fruit or vegetables, and a significant proportion regularly not eating for whole days at a time, leading to deficiencies in vital nutrients. The Benefits and Nutrition Study (BEANS) was led by the University of Nottingham’s Division of Food, Nutrition and Dietetics to examine food insecurity among people who claim Universal Credit. Their findings, published in the European Journal of Nutrition, show that 85% of those in receipt of Universal Credit are food ...

A comprehensive study from Karolinska Institutet shows that people with fatty liver disease have almost twice the mortality rate of the general population. They have an increased risk of dying from both liver diseases and common diseases such as cancer and cardiovascular disease, according to the study published in The Journal of Hepatology. It is estimated that one in five people in Sweden has fatty liver disease known as MASLD (metabolic dysfunction-associated steatotic liver disease), and globally it may be as many as one in four. The disease is caused by overweight or obesity and is characterised by an excessive ...

Excess weight in mid-life is a known risk factor for kidney cancer, but new research indicates that weight patterns throughout life may also affect an individual’s likelihood of developing this malignancy. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. To assess weight patterns and their associations with kidney cancer and its different subtypes, investigators analyzed information on 204,364 individuals from the NIH-AARP Diet and Health Study, including body mass index (BMI) data when participants entered the study (an average age of 61.6 years), and prior BMI recordings at 18, 35, and 50 ...

Almost half of people who died with inflammatory bowel disease (IBD) died prematurely, according to a study published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.241117 that used machine learning models to predict death. Canada has some of the highest rates of IBD worldwide, which includes Crohn disease and ulcerative colitis. People with IBD have shorter life expectancy than people without such diseases, and they can develop other chronic health conditions related to their IBD. The study found that people with IBD are at risk for premature death (defined ...

Existing tax policies during the energy transition from fossil fuels to renewable sources will lead to major energy injustices and skewed priorities, new research published in Climate Policy shows. The peer-reviewed study found that electricity serving primary needs, such as heating or lighting, ultimately costs three times more than electricity for tertiary needs such as long-distance mobility – mostly due to taxation policies. Further highlighting the ongoing social inequalities of fuel and related policies, the findings also demonstrate within the European Union (EU), the wealthiest 1% of all its population is responsible for 66% of the distance ...

A simple urine test could accurately show the recurrence of kidney cancer at an early stage, potentially sparing patients invasive scans and enabling faster access to treatment, new research has shown. The findings are presented today [Monday 24 March 2025] at the European Association of Urology (EAU) Congress in Madrid and have been accepted for publication in European Urology Oncology. The test analyses the distinctive profiles of certain types of sugar molecules, called glycosaminoglycans which are found in urine. These profiles are known as the GAGome. The international AURORAX-0087A (AUR87A) study is assessing whether a GAGome test can accurately detect ...

London, UK: The largest analysis to examine the best way to lower levels of ‘bad’ cholesterol in patients with blocked arteries shows that they should immediately be given a combination of a statin and another drug called ezetimibe, rather than statins alone. This could prevent thousands of deaths a year from heart attacks, strokes and other cardiovascular diseases. The meta-analysis of 108,353 patients in 14 studies who were at very high risk of suffering heart attack or stroke, or who had already suffered one of these cardiovascular events is published in the journal Mayo Clinic Proceedings ...