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Novel truncated RNAs from jumping DNA encode reverse transcriptases in aging human brain

2025-06-04
Alzheimer’s disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older. The disease has proven difficult to develop new treatments for, and available treatment options are limited. With cases in the U.S. projected to more than double by 2050, more therapies are needed to improve patients’ quality of life and reduce the burden on the health care system and family caregivers.   Scientists at Sanford Burnham Prebys and elsewhere have recently reported real-world links in medical records associating common HIV drugs with a reduced incidence of Alzheimer’s disease. The ...

Most-viewed TikTok videos on inflammatory bowel disease show low quality

2025-06-04
June 4, 2025 — The most popular TikTok videos related to inflammatory bowel disease (IBD) have millions of views – but very low scores for quality of medical information, reports a study in the May/June issue of Gastroenterology Nursing, Official Journal of the Society of Gastroenterology Nurses and Associates. The journal is published in the Lippincott portfolio by Wolters Kluwer. "Social media platforms such as TikTok have the potential to reach a wide audience of people living with IBD, particularly young adults," comments lead author Samantha Winders, ...

Study shows making hydrogen with soda cans and seawater is scalable and sustainable

2025-06-04
Hydrogen has the potential to be a climate-friendly fuel since it doesn’t release carbon dioxide when used as an energy source. Currently, however, most methods for producing hydrogen involve fossil fuels, making hydrogen less of a “green” fuel over its entire life cycle.  A new process developed by MIT engineers could significantly shrink the carbon footprint associated with making hydrogen.  Last year, the team reported that they could produce hydrogen gas by combining seawater, recycled soda cans, and caffeine. The question then was whether the benchtop process could be applied at an industrial scale, and at ...

Could dietary changes -- even after obesity -- help prevent pancreatic cancer?

2025-06-04
Pancreatic cancer is one of the deadliest forms of cancer, killing 87% of patients within five years. Previous studies have shown that obesity can increase pancreatic cancer risk by around 50%. In a new study from the University of California, Davis, researchers showed evidence that switching from a high-fat diet to a low-fat diet slowed pancreatic precancer development in mice, even after weight gain and precancerous changes began. The research was published in the Journal of Nutrition. “This study shows that managing excess body weight is very important,” said corresponding author Gerardo Mackenzie, professor and chair of the UC Davis Department ...

From rubble to rockets: Turning scrap metal into essential equipment

2025-06-04
Worcester Polytechnic Institute (WPI) has been awarded $6.3 million for a groundbreaking initiative that could transform additive manufacturing by enabling the rapid production of high-quality components from scrap metal. This innovative approach to additive manufacturing, funded by the Defense Advanced Research Projects Agency (DARPA), aims to ensure that essential components can be produced even in the most resource-limited environments, including where access to traditional supply chains is limited, such as battlefields or remote search-and-rescue locations. The ...

Museum specimens offer new lens on pollution history

2025-06-04
A new study highlights a surprising lens for tracking pollution trends over centuries: preserved plants and animals housed at natural history museums around the world. According to Shane DuBay, a researcher at The University of Texas at Arlington, these specimens contain valuable environmental data that can help scientists reconstruct pollution trends spanning more than 200 years. “We often lack the historical pollution data needed to understand the links between environmental contamination and long-term health effects, such as cancer, asthma, cognitive disorders and premature ...

Studying the 12C+12C fusion reaction at astrophysical energies using HOPG target

2025-06-04
A research team from the Institute of Modern Physics and Sichuan University has performed a direct measurement of the 12C+12C fusion reaction at a center-of-mass energy of 2.22 MeV using the LEAF accelerator facility. The experiment employed a highly intense 12C2+ beam, a highly oriented pyrolytic graphite (HOPG) target known for its low background, and a ΔE–E telescope combining a Time Projection Chamber and silicon detectors. This setup enabled detection of extremely rare fusion events, with a thick-target yield on the order of 10−17 ...

Bacteria hitch a ride on yeast puddles to zoom around

2025-06-04
In the world of microorganisms, microbes compete for turf, spew chemicals at foes, and sometimes exploit the microscopic terrain to gain an edge. In a study published June 4 in the Cell Press journal Biophysical Journal, researchers found that bacteria can speed up by using the fluid pockets shaped by neighboring yeast cells. These microscopic moisture trails allow bacteria to swim farther and spread faster—revealing a new way for microbes to travel through soil, plants, and the human body.  “When studying microbial interactions, research often focuses on the chemical nature of these interactions,” says lead author Divakar Badal of Cornell University. ...

New non-invasive method discovered to enhance brain waste clearance

2025-06-04
Scientists at the Institute for Basic Science (IBS) have uncovered a non-invasive method to boost the brain’s natural waste drainage system—a discovery that could open new avenues for tackling age-related neurological disorders. In a study published in Nature, researchers from the IBS Center for Vascular Research, led by Director KOH Gou Young, along with senior researchers JIN Hokyung, YOON Jin-Hui, and principal researcher HONG Seon Pyo, demonstrated that precisely stimulating the lymphatics under skin on the neck and face can significantly enhance the flow of cerebrospinal ...

A summer like no other: inside 2023’s record-smashing North Atlantic marine heatwave

2025-06-04
In a UNSW-led Nature study published today, researchers say that an off-the-scale marine heatwave in the North Atlantic Ocean in 2023 was caused by record-breaking weak winds combined with increased solar radiation – all on the back of ongoing climate change. From Greenland to the Sahara and across to the Americas, the waters of the North Atlantic Ocean warmed at an unprecedented speed in the summer of 2023. “The intensity of the warming in that single summer was equivalent to about two decades worth of warming for the North Atlantic,” says lead author Professor Matthew England from UNSW Sydney. “While ...

Many possible futures: How dopamine in the brain might inform AI that adapts quickly to change

2025-06-04
What if your brain had a built-in map – not of places, but of possible futures? Researchers at the Champalimaud Foundation (CF) blend neuroscience and artificial intelligence (AI) to reveal that populations of dopamine neurons in the brain don’t just track whether rewards are coming – they encode maps of when those rewards might arrive and how big they might be. These maps adapt to context and may help explain how we weigh risks, and why some of us act on impulse while others hold back. Strikingly, this biological ...

Research shows rivers release ancient carbon dioxide into the atmosphere, uncovering a greater role for plants and soil in the carbon cycle

2025-06-04
A new study has revealed for the first time that ancient carbon, stored in landscapes for thousands of years or more, can find its way back to the atmosphere as CO₂ released from the surfaces of rivers. The findings, led by scientists at the University of Bristol and the cover story of the journal Nature, mean plants and shallow soil layers are likely removing around one gigatonne more CO₂ each year from the atmosphere to counteract this, emphasising their pivotal and greater part in combating climate change. Lead author Dr Josh ...

Hypertension, diabetes, and high cholesterol awareness among US adults

2025-06-04
About The Study: The proportion of U.S. adults who were unaware of having hypertension increased significantly over the study period (2013 to 2023), particularly in young adults and women, while diabetes and high cholesterol level unawareness remained stable. By the 2021 to 2023 cycle, approximately 1 in 6 adults with hypertension and 3 in 10 with diabetes were unaware of their condition. Corresponding Author: To contact the corresponding author, Rishi K. Wadhera, MD, MPP, MPhil, email rwadhera@bidmc.harvard.edu. To access the embargoed study: Visit our For The Media website at ...

Longitudinal outcomes of the COVID-19 pandemic on youth physical fitness

2025-06-04
About The Study: In this cohort study of schools, a COVID-19–related decline in youth physical fitness was observed. Compared with pre-pandemic and post-pandemic periods, cardiorespiratory fitness and musculoskeletal fitness healthy fitness zone achievement were significantly lower during the pandemic, but the reduction did not appear to be associated with extended remote or hybrid environments. Corresponding Author: To contact the corresponding author, Andjelka Pavlovic, PhD, email andjelka.pavlovic@ttuhsc.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.13721) Editor’s ...

Study shows loss of Y in blood cells hinders immune response to cancer

2025-06-04
A study initiated by a University of Arizona Comprehensive Cancer Center physician-scientist defined for the first time how loss of the Y chromosome in male immune cells negatively affects immune system function, which may explain why loss of Y is associated with lower cancer survival rates. The paper “Concurrent loss of the Y chromosome in cancer and T cells impacts outcome,” was published today in Nature. In males, each cell in the body usually contains one X and one Y chromosome. “Loss of Y” is a common, nonhereditary ...

Loss of Y chromosome leads to poor cancer outcomes

2025-06-04
When cancer cells in male patients and immune cells in their tumors both lose the Y chromosome, those patients tend to experience poorer outcomes than patients without Y chromosome loss, according to new findings from Cedars-Sinai investigators. Their work, published in the scientific journal Nature, could lead to ways to make some cancer treatments more effective. The Y chromosome is one of two chromosomes that determine biological sex in mammals. Females have two X chromosomes, males have one X and one Y chromosome, and it ...

The atmosphere’s growing thirst is making droughts worse, even where it rains

2025-06-04
(Santa Barbara, Calif.) — Hot air holds more moisture. That’s why you can blow your hair dry even after a steamy shower. It’s also what dumps rain in the tropics and sucks water from desert soils. A new study, published in Nature, shows that the atmosphere’s growing thirst for water is making droughts more severe, even in places where rainfall has stayed the same. The paper details how this “thirst” has made droughts 40% more severe across the globe over the course of the past 40 years. “Drought is based on the difference between water supply (from precipitation) and atmospheric water demand. ...

Colorectal cancer leaves lasting toll on women’s sexual health

2025-06-04
A new University of British Columbia-led study is shedding light on a long-overlooked consequence of colorectal cancer: the lasting toll it can take on women’s sexual health, even years after treatment ends. Researchers analyzed health data from more than 25,000 women in B.C. diagnosed with colorectal cancer between 1985 and 2017, comparing their experiences to those of cancer-free women. Cancer treatments such as surgery, chemotherapy and radiation were linked to a range of long-term sexual health issues, including a 67 per cent higher risk of dyspareunia—pain during sex—a ...

New technology developed at the Lewis Katz School of Medicine at Temple University promises faster, earlier diagnosis of deadly form of heart failure

2025-06-04
(Philadelphia, PA) – A novel screening approach developed by physicians at the Lewis Katz School of Medicine at Temple University shows significant promise for improving the detection of pulmonary arterial hypertension (PAH)—a life-threatening form of heart failure related to high blood pressure in the lung circulation that is often overlooked due to vague symptoms such as fatigue and shortness of breath. The new research, published online April 5 in the American Heart Journal, shows that the virtual echocardiography screening ...

PolyU scholar honored with the Hong Kong Engineering Science and Technology Award for contributions to Web3 and digital economy

2025-06-04
Scholars from the Hong Kong Polytechnic University (PolyU) are committed to pioneering research excellence and providing innovative solutions to the ever-changing needs of society and technology. Prof. AU Man Ho Allen, Professor and Associate Head (Research and Development) of the Department of Computing at PolyU, has been recognised with the prestigious Hong Kong Engineering Science and Technology (HKEST) Award 2024-25 for his outstanding contributions to the Web3 ecosystem and the digital economy. Prof. AU has made significant contributions to information security, applied cryptography, and blockchain technology, pioneering ...

Nationwide study finds that leaks in natural gas pipelines contribute to hazardous particulate air pollution

2025-06-04
Embargoed for Release Until June 4, 2025    NATIONWIDE STUDY FINDS THAT LEAKS IN NATURAL GAS PIPELINES CONTRIBUTE TO HAZARDOUS PARTICULATE AIR POLLUTION New research finds that methane leaks in energy-intensive states like Texas lower the air quality for people in neighboring states Herndon, VA, June 4, 2025 -- In March 2022, 14 residents of a four-story apartment building in Silver Spring, Maryland, were hospitalized when a gas leak from a cut pipeline caused a major explosion. Every year in the United States, there are hundreds of natural gas (or methane) pipeline leaks -- caused by corrosion, equipment malfunctions, and construction ...

‘Eye’ on health: AI detects dizziness and balance disorders remotely

2025-06-04
Artificial intelligence is playing an increasingly vital role in modern medicine, particularly in interpreting medical images to help clinicians assess disease severity, guide treatment decisions and monitor disease progression. Despite these advancements, most current AI models are based on static datasets, limiting their adaptability and real-time diagnostic potential. To address this gap, researchers from Florida Atlantic University and collaborators, have developed a novel proof-of-concept deep ...

EyeCare4Kids™ names Maggie Cline as new CEO

2025-06-04
Midvale, UT (June 4, 2025) – EyeCare4Kids™, a non-profit organization that provides professional eye care services to low-income, visually impaired children and underserved families across the southwest United States and Africa, today announced the promotion of Maggie Cline, MPH, to Chief Executive Officer (CEO). Ms. Cline joined EyeCare4Kids in 2022 and served as Executive Director Utah, where she oversaw the delivery of more than 50,000 vision services annually at school clinics, community centers, and other underserved areas across the state. Ms. Cline succeeds board-certified optician Joseph Carbone, who founded the organization in 2001 and will transition to a role focused on ...

Moderate exercise slows brain aging: U-shaped association revealed by accelerometry

2025-06-04
A new study leveraging accelerometer and brain MRI data reveals that moderate levels of physical activity may help slow brain aging. Led by Associate Professor Chenjie Xu from the School of Public Health at Hangzhou Normal University, in collaboration with institutions including Tianjin University of Traditional Chinese Medicine and Tianjin Medical University, the study is published in Health Data Science. Analyzing 16,972 participants from the UK Biobank, researchers applied a LightGBM machine learning algorithm to over 1,400 image-derived phenotypes to predict each individual’s "brain age." The findings indicate a U-shaped association between physical activity (PA) ...

Bat viruses similar to MERS have potential to jump to humans

2025-06-04
PULLMAN, Wash.--A group of bat viruses closely related to the deadly Middle East respiratory syndrome coronavirus (MERS-CoV) could be one small mutation away from being capable of spilling over into human populations and potentially causing the next pandemic. A recent study published in the journal Nature Communications examined an understudied group of coronaviruses known as merbecoviruses — the same viral subgenus that includes MERS-CoV — to better understand how they infect host cells. The research ...
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