Study: suppressing key protein may unlock immunotherapy for Glioblastoma
2025-03-17
MIAMI, FLORIDA (EMBARGOED UNTIL MARCH 17, 2025, AT NOON EDT) – Glioblastoma has remained one of the toughest cancers to treat, resisting even the latest advances in immunotherapy. But new research from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, suggests a way forward: suppressing a protein called ZNF638 triggers an antiviral immune response, making immune checkpoint inhibitors more effective. The discovery not only offers a potential new treatment strategy but also identifies ...
Early surgical intervention in children with sleep-disordered breathing reduces need for doctor visits, prescriptions
2025-03-17
In a randomized trial, Mass General Brigham researchers found the surgical removal of tonsils and adenoids was effective for children with snoring and mild sleep apnea
An estimated 6 to 17 percent of children have sleep-disordered breathing, ranging from snoring to sleep apnea, which can cause behavioral, neurocognitive, cardiovascular, and cardiometabolic issues. A new study from Mass General Brigham researchers reveals that adenotonsillectomy—the surgical removal of tonsils and adenoids—is an effective early intervention for these children. Their results are published in JAMA Pediatrics.
“To ...
Statin use and risk of hepatocellular carcinoma and liver fibrosis in chronic liver disease
2025-03-17
About The Study: This cohort study found that statin use was associated with a reduced risk of hepatocellular carcinoma and hepatic decompensation in patients with chronic liver disease. These findings provide support for the potential role of statins in prevention of hepatocellular carcinoma and liver disease progression.
Corresponding Authors: To contact the corresponding authors, email Jonggi Choi, MD, PhD, (j.choi@amc.seoul.kr) and Raymond T. Chung, MD, (chung.raymond@mgh.harvard.edu).
To ...
Gender-affirming hormone therapy and depressive symptoms among transgender adults
2025-03-17
About The Study: In this longitudinal observational cohort study, gender-affirming hormone therapy was associated with lower rates of moderate-to-severe depressive symptoms, highlighting the importance of gender-affirming primary care models for transgender, nonbinary, and gender diverse patients.
Corresponding Author: To contact the corresponding author, Sari L. Reisner, ScD, MA, email sreisner@umich.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2025.0955)
Editor’s ...
Surgery in kids with mild sleep-disordered breathing tied to fewer doctor visits, meds
2025-03-17
What: Surgical removal of enlarged tonsils and adenoids in children with mild sleep-disordered breathing (SDB) appears to significantly reduce the frequency of medical office visits and prescription medicine use in this group, according to a clinical study supported by the National Institutes of Health (NIH). The findings, published in JAMA Pediatrics, show that the surgery, called adenotonsillectomy, was tied to a 32% reduction in medical visits and a 48% reduction in prescription use among children with a mild form of the condition.
SDB refers to breathing disturbances during sleep ...
Magnetic microalgae on a mission to become robots
2025-03-17
Stuttgart – A team of researchers at the Max Planck Institute for Intelligent Systems (MPI-IS) in Stuttgart developed a biohybrid micro swimmer covered with magnetic material, whose swimming ability is largely unaffected by the coating. The team from the Physical Intelligence Department at MPI-IS published their work in the journal Matter, which covers a wide range of materials science research.
In nature, the ten-micron small, single-cell microalgae are fantastic swimmers, propelled by their two whip-like ...
Impact journals to participate at the AACR Annual Meeting 2025
2025-03-17
Impact Journals is proud to participate in the American Association for Cancer Research (AACR) Annual Meeting 2025, taking place April 25-30 in Chicago, Illinois.
BUFFALO, NY- March 17, 2025 – Impact Journals is pleased to announce its participation as an exhibitor at the upcoming American Association for Cancer Research (AACR) Annual Meeting 2025. The meeting is scheduled for April 25-30, 2025, at the McCormick Place Convention Center in Chicago, Illinois.
The 2025 AACR Annual Meeting theme, “Unifying Cancer Science and Medicine: A Continuum of Innovation ...
Webb telescope captures its first direct images of carbon dioxide outside solar system
2025-03-17
The James Webb Space Telescope has captured its first direct images of carbon dioxide in a planet outside the solar system in HR 8799, a multiplanet system 130 light-years away that has long been a key target for planet formation studies.
The observations provide strong evidence that the system’s four giant planets formed in much the same way as Jupiter and Saturn, by slowly building solid cores. They also confirm Webb can do more than infer atmospheric composition from starlight measurements—it can directly analyze the chemistry ...
NIH-sponsored trial of Lassa vaccine opens
2025-03-17
A National Institutes of Health (NIH)-sponsored clinical trial of a candidate vaccine to prevent Lassa fever has begun enrolling participants at the University of Maryland School of Medicine, Baltimore. Lassa fever is a viral hemorrhagic disease that can be fatal and that causes permanent hearing loss in up to one-third of those who contract it. Lassa virus is spread by rodents, known as multimammate rats, that are native to many countries in West Africa. The virus can also be spread from person to person. Currently, there are no specific drug treatments or vaccines for Lassa fever. NIH’s National Institute of Allergy and ...
Pro-life people partly motivated to prevent casual sex, study finds
2025-03-17
(Note: The following press release was prepared by Brunel University of London.)
Abortion is murder – the emotive rallying cry popular with pro-life campaigners keen to convert others to their cause. But what if opposition to abortion isn’t all about sanctity-of-life concerns, and instead at least partly about discouraging casual sex?
That’s what psychology researchers found in experiments designed to test what really drives anti-abortion attitudes in the USA. The study, published today in ...
Top locations for ocean energy production worldwide revealed
2025-03-17
As global electricity demand grows, traditional energy sources are under strain. Oceans, which cover more than 70% of Earth’s surface, offer vast potential for clean energy from renewable resources such as ocean currents and waves.
However, marine renewable energy development is still in its early stages compared to wind and solar power. One challenge is identifying the most feasible and economically viable locations for ocean current energy projects. While many studies have focused on regional ocean current energy resource assessment, a global evaluation based on actual data has been lacking – until now.
Using more ...
New AI model analyzes full night of sleep with high accuracy in largest study of its kind
2025-03-17
New York, NY [March 17, 2025]—Researchers at the Icahn School of Medicine have developed a powerful AI tool, built on the same transformer architecture used by large language models like ChatGPT, to process an entire night’s sleep. To date, it is one of the largest studies, analyzing 1,011,192 hours of sleep. Details on their findings were reported in the March 13 online issue of the journal Sleep [https://doi.org/10.1093/sleep/zsaf061].
The model, called patch foundational transformer for sleep (PFTSleep), ...
Combination of cosmic processes shapes the size and location of sub-Neptunes
2025-03-17
UNIVERSITY PARK, Pa. — A combination of cosmic processes shapes the formation of one of the most common types of planets outside of our solar system, according to a new study led by researchers at Penn State. The research team used data from NASA’s Transiting Exoplanet Survey Satellite (TESS) to study young sub-Neptunes — planets bigger than Earth but smaller than Neptune — that orbit close to their stars. The work provides insights into how these planets might migrate inward or lose their atmosphere during their early stages.
A paper describing the ...
New study shows regular exercise pre-hospitalization is linked to better outcomes in heart failure
2025-03-17
Heart failure is a major health concern, especially for ageing populations—it significantly increases mortality rates, and severely impacts quality of life for those affected. Exercise therapy has been shown to be particularly effective for patients with heart failure. Previous research, however, has mainly examined the benefits of exercise after a diagnosis of heart failure. There is a considerable gap when it comes to our understanding of the role that exercise plays before a patient with heart failure is hospitalized.
Now, in a recent study published in the European Journal of Preventive Cardiology on 19 February 2025, researchers from Japan have explored the link between ...
New discovery in plant–pest warfare could lead to sustainable farming solutions
2025-03-17
As global food demand continues to increase, effective pest control remains one of agriculture’s most pressing challenges. Worldwide, farmers apply nearly 4 million tons of chemical pesticides annually to protect their crops, representing a $60 billion industry. While these compounds have significantly boosted agricultural productivity, their widespread use has raised concerns regarding environmental impact, health risks, and the long-term sustainability of modern farming.
The two-spotted spider mite, Tetranychus urticae, exemplifies the limitations of conventional pesticide-based pest management in agriculture and horticulture. ...
Make Indian sign language an official language and open more schools for deaf and hard-of-hearing students, Cambridge study advises Indian government
2025-03-17
University of Cambridge media release
Make Indian Sign Language an official language and open more schools for deaf and hard-of-hearing students, Cambridge study advises Indian Government
UNDER STRICT EMBARGO UNTIL 15:30 INDIA STANDARD TIME / 10:00 UK TIME / 06:00 US ET ON MONDAY 17TH MARCH 2025
Around one in five (over 19%) of India’s deaf and hard-of-hearing children were out-of-school in 2014, according to a survey conducted for the Indian Government.* A new study calls on the Government to address this ongoing educational crisis by recognising ...
Deep dive into space turns up new Spitzer bubbles
2025-03-17
To learn more about the deepest reaches of our own galaxy and the mysteries of star formation, Japanese researchers have created a deep learning model. The Osaka Metropolitan University-led team used artificial intelligence to pore through the vast amounts of data being acquired from space telescopes, finding bubble-like structures that had not been included in existing astronomical databases.
The Milky Way galaxy we live in, like other galaxies in the universe, has bubble-like structures formed mainly during the birth and activity of high-mass stars. These so-called Spitzer bubbles hold important clues to understanding the process of star formation and galaxy evolution.
Graduate School of ...
Attention can be used to drive cooperation – new study
2025-03-17
Our ability to cooperate with others may be influenced by how our attention is captured and directed, as much as by how altruistic we are feeling.
According to a new study by researchers at the University of Birmingham jointly with the University of Zurich, choices made for individual reward or cooperatively for a joint reward can be influenced by presenting information to participants in configurations that naturally draw their attention. The results are published today in Communications Psychology.
Cooperation – defined as the ability of individuals to incur a personal cost for the benefit ...
A post-treatment blood test could inform future cancer therapy decisions
2025-03-17
In the continuing evolution of personalized medicine, a new Yale study has found evidence to support the value of a tool that measures the presence of cancer-derived molecules in the blood of patients with lung cancer years after their treatment.
This tool is a type of molecular residual disease (MRD)detector, which is used after patients have completed their primary treatment in order to monitor their cancer status. Researchers say it could inform clinical intervention, including whether to restart or intensify treatment.
“MRD detection is the future — allowing ...
Bridging Nature and Nurture: Study reveals brain's flexible foundation from birth
2025-03-17
Riddle me this: how can it be that reading these words activates nearly identical word-sensitive patches of the brain’s visual system in you and nearly every other reader of this story? And that a different set of face-sensitive visual regions—again in almost identical positions in each reader’s brain—would activate to process the faces of the researchers, should you meet them?
For years, researchers have debated how our brains consistently develop areas specialized for recognizing faces, objects, words, and places, despite individuals having vastly different life experiences.
Two competing theories have dominated this discussion. One ...
Newborns with heart defects may face a higher risk of developing childhood cancer
2025-03-17
Research Highlights:
Newborns with congenital heart defects may have a higher risk of developing childhood cancer compared to children born without a heart abnormality.
Congenital heart defects in newborns may also signal an elevated cancer risk for their mothers.
Researchers suggest a multidisciplinary team of health care professionals to care for newborns with congenital heart defects and their moms.
Embargoed until 4 a.m. CT/5 a.m. ET Monday, March 17, 2025
DALLAS, March 17, 2025 — Being born with a heart defect may ...
Continued medication important for heart failure patients
2025-03-17
Patients who have been treated for heart failure and experience an improvement of their pump function, are still at higher risk of heart-related death or hospitalisation if they stop taking heart failure medications. This is according to a new study from Karolinska Institutet published in the top-ranked journal Circulation.
“Our finding raises awareness about the importance of implementing and not withdrawing medical treatments in daily clinical practice even if patients with heart failure experience an improvement in symptoms and pump function,” says the study’s last author Gianluigi Savarese, docent and senior ...
Tools to succeed: Learning support for new nurses
2025-03-17
First-year nurses often have difficulties while bridging the gap between educational theory and required workplace practice. In the fast-paced medical field, sufficient guidance is hard to come by, so new nurses must actively learn on their feet through modeling senior nurses’ actions and techniques. There are several studies on learning from role models, but no specific tools that focus on new nurses’ learning progress through this practice.
A new tool, called the Modeling Scale for Novice Nurses, has been developed by Dr. Yayoi Nagano and Professor Yasuko Hosoda at Osaka Metropolitan University’s Graduate School of Nursing. They conducted a questionnaire on ...
A breakthrough in green hydrogen peroxide production: KIST develops carbon catalyst utilizing airborne oxygen
2025-03-17
Hydrogen peroxide is one of the world's top 100 industrial chemicals with a wide range of applications in the chemical, medical, and semiconductor industries. Currently, hydrogen peroxide is mainly produced through the anthraquinone process, but this process has several problems, including high energy consumption, the use of expensive palladium catalysts, and environmental pollution due to by-products. In recent years, an environmentally friendly method of producing hydrogen peroxide by electrochemical reduction of oxygen using inexpensive carbon catalysts has gained attention. However, this method has been limited by the high cost of injecting high-purity oxygen gas and ...
Travellers: beware of Oropouche virus. Is it the next Zika?
2025-03-17
Heading south for the winter? Oropouche virus, a new infectious disease, has been reported in travellers from Canada and the United States who visited Bolivia, Brazil, Peru, and Cuba. An article published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.241440 provides an overview of this emerging virus.
Similar to viruses like dengue and Zika, Oropouche virus symptoms include fever, chills, headache, and muscle aches. The incubation period is 3–10 days, and symptoms last 2–7 days and may recur weeks later in some ...
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