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A planetary boundary for geological resources: Limits of regional water availability

A planetary boundary for geological resources: Limits of regional water availability
2025-03-13
Geological resources such as critical metals and minerals, essential for the diffusion of technologies such as renewable energy and energy storage towards a decarbonized society, are indispensable for supporting modern life in the form of various products and services. Their demand is expected to increase in the coming years owing to global population as well as economic growth. Thus far, scientists and policymakers have primarily discussed geological resource availability from the viewpoint of reserves and resources in the ecosphere and technosphere. However, resources such as ...

Astronomy’s dirty window to space

Astronomy’s dirty window to space
2025-03-13
When we observe distant celestial objects, there is a possible catch: Is that star I am observing really as reddish as it appears? Or does the star merely look reddish, since its light has had to travel through a cloud of cosmic dust to reach our telescope? For accurate observations, astronomers need to know the amount of dust between them and their distant targets. Not only does dust make objects appear reddish (“reddening”), it also makes them appear fainter than they really are (“extinction”). It’s like we are looking out into space through a dirty ...

New study reveals young, active patients who have total knee replacements are unlikely to need revision surgery in their lifetime

2025-03-13
A 40-year study by Hospital for Special Surgery (HSS) researchers has found that active young adults who underwent total knee replacement were unlikely to require knee replacement revision in their lifetime, according to a new study shared today in a podium presentation at the American Academy of Orthopaedic Surgeons 2025 Annual Meeting.1 “As an increasing number of younger adults in their 40s and 50s consider total knee replacement, many wonder how long knee implants last before requiring a revision procedure,” ...

Thinking outside the box: Uncovering a novel approach to brainwave monitoring

2025-03-13
ROCHESTER, Minnesota — Mayo Clinic researchers have found a new way to more precisely detect and monitor brain cell activity during deep brain stimulation, a common treatment for movement disorders such as Parkinson's disease and tremor. This precision may help doctors adjust electrode placement and stimulation in real time, providing better, more personalized care for patients receiving the surgical procedure. The study is published in the Journal of Neurophysiology.  Deep brain stimulation (DBS) involves implanting electrodes in the brain that emit electrical pulses to alleviate symptoms. The electrodes remain inside the brain connected to a battery implanted near ...

Combination immunotherapy before surgery may increase survival in people with head and neck cancer

Combination immunotherapy before surgery may increase survival in people with head and neck cancer
2025-03-13
CHAPEL HILL, North Carolina—Researchers conducting a clinical trial of immunotherapy drugs for people with head and neck squamous cell carcinomas (HNSCCs) found that patients responded better to a combination of two immunotherapies than patients who received just one immunotherapy drug. The scientists also analyzed immune cells in each person’s tumor after one month of immunotherapy to see which type of immune cells were activated to fight their cancer, suggesting that some of the cells and targets they identified could help individualize treatment benefit. The findings appeared March 13, 2025 in Cancer Cell. HNSCCs occur in the oral cavity, pharynx, hypopharynx, larynx, nasal ...

MIT engineers turn skin cells directly into neurons for cell therapy

2025-03-13
CAMBRIDGE, MA -- Converting one type of cell to another — for example, a skin cell to a neuron — can be done through a process that requires the skin cell to be induced into a “pluripotent” stem cell, then differentiated into a neuron. Researchers at MIT have now devised a simplified process that bypasses the stem cell stage, converting a skin cell directly into a neuron. Working with mouse cells, the researchers developed a conversion method that is highly efficient and can produce more than 10 neurons from a single skin cell. If replicated in human ...

High sugar-sweetened beverage intake and oral cavity cancer in smoking and nonsmoking women

2025-03-13
About The Study: High sugar-sweetened beverage intake was associated with a significantly increased risk of oral cavity cancer in women, regardless of smoking or drinking habits, yet with low baseline risk in this study. Additional studies are needed in larger cohorts, including males, to validate the impact of these findings. Corresponding Author: To contact the corresponding author, Brittany Barber, MD, MSc, email bbarber1@uw.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaoto.2024.5252) Editor’s ...

Area socioeconomic status, vaccination access, and female HPV vaccination

2025-03-13
About The Study: In this cross-sectional study of area deprivation, vaccination access, and human papillomavirus (HPV) vaccination status in Osaka City, Japan, higher socioeconomic status and higher medical facility access were associated with higher cumulative HPV vaccination uptake. These findings suggest that further strategies, including a socioecologic approach, are needed to increase HPV vaccination and reduce disparities in uptake. Corresponding Author: To contact the corresponding ...

Checking PSA levels too soon after prostate cancer surgery can lead to overtreatment

2025-03-13
After surgical removal of the prostate to treat prostate cancer, clinicians monitor Prostate Specific Antigen (PSA) levels. Persistently elevated PSA levels indicate residual cancer and are linked to worse outcomes. But in a paper published in JAMA Oncology, Mass General Brigham researchers found that the current standard monitoring time of one-and-a-half to two months following surgery is too short to accurately identify recurrence and inform treatment decisions. Rather, PSA levels should be measured for at least three months to avoid overtreatment. “Checking ...

CityUHK researchers develop an innovative bio-detection platform for cancer early screening and disease monitoring

CityUHK researchers develop an innovative bio-detection platform for cancer early screening and disease monitoring
2025-03-13
Cancer continues to be a leading cause of mortality worldwide, highlighting the urgent need to develop more advanced, efficient, and early detection methods. Addressing this critical need, City University of Hong Kong (CityUHK) is leading a groundbreaking research project aimed at developing an innovative technology platform for early detection of cancer and personalised treatment. The project aims specifically to enhance the detection of circulating tumor cells (CTCs), paving the way for significant advancements in cancer diagnosis and care. This is one of the first batch of projects that has secured funding by the RAISe+ Scheme. The RAISe+ Scheme (the Research, ...

English translation of harnessing data for improved productivity: managing the full life cycle of data licensed at the London Book Fair

English translation of harnessing data for improved productivity: managing the full life cycle of data licensed at the London Book Fair
2025-03-13
On March 11, 2025, at the China Collective Stand of the London Book Fair, Tsinghua University Press (TUP) and the University of Toronto Press (UTP) sign a licensing agreement for the English version of Harnessing Data for Improved Productivity: Managing the Full Life Cycle of Data. This collaboration is a big step forward in putting China’s data management innovations on the global map, showcasing the nation’s cutting-edge achievements through leading ...

COVID-19 discovery opens door to new treatments for chronic lung problems

COVID-19 discovery opens door to new treatments for chronic lung problems
2025-03-13
University of Virginia School of Medicine scientists have discovered how severe COVID-19 can destroy immune cells’ ability to repair the lungs, helping explain the lingering effects of long COVID. The findings suggest a new treatment approach for long COVID as well as other conditions, both short-term and chronic, caused by respiratory infections such as the flu. Led by UVA’s Jie Sun, PhD, the researchers found that severe viral infections including COVID-19 and the flu can gravely damage a key organelle inside immune cells called macrophages. Macrophages direct lung repair after tissue damage, but their ability to do so is crippled ...

Stanford Medicine research explores the promise and perils of AI in citizen science

Stanford Medicine research explores the promise and perils of AI in citizen science
2025-03-13
(Toronto, March 13, 2025) A new study published in JMIR Public Health and Surveillance by a team from Stanford Medicine investigates the potential of artificial intelligence (AI) to revolutionize citizen science and advance health equity. The study, titled “The Promise and Perils of Artificial Intelligence in Advancing Participatory Science and Health Equity in Public Health,” explores how AI technologies can empower communities to actively participate in scientific research and addresses critical ethical considerations. This research, published by JMIR Publications, examines the potential of AI to significantly enhance citizen science by enabling more inclusive ...

New approaches to tackle coupled urban risks: a people-centric and complex systems perspective

New approaches to tackle coupled urban risks: a people-centric and complex systems perspective
2025-03-13
As urbanization surges and climate change intensifies, cities worldwide are facing an increasing number of coupled risks. A recent paper published in Engineering offers fresh insights into understanding and managing these risks. The complexity of coupled risks in cities, which result from the compounded effects of interacting uncertainties across multiple interdependent objectives, is a major concern. A disruption in one urban subsystem can trigger a chain reaction, affecting other subsystems and leading to unforeseen consequences. For example, the extreme rainfall not only damaged infrastructure ...

OFC conference to showcase energy-efficient optical links that result in faster, low-power photonic chips

2025-03-13
Researchers have demonstrated an integrated optical link on a silicon wafer that exhibits high-speed data transmission with very low power consumption. The advance, which was possible because of new low-energy membrane photonic devices made from indium phosphide, could help improve the power efficiency of integrated photonic circuit boards and chip packages without compromising speed. Tatsurou Hiraki from NTT Corporation in Japan will present this research at OFC, the premier global event for optical communications and networking, which will take place 30 March – 03 April 2025 at the Moscone Center ...

Ultra-low dose CT aids pneumonia diagnosis in immunocompromised patients

Ultra-low dose CT aids pneumonia diagnosis in immunocompromised patients
2025-03-13
OAK BROOK, Ill. – Denoised ultra-low dose CT can effectively diagnose pneumonia in immunocompromised patients using only 2% of the radiation dose of standard CT, according to a study published today in Radiology: Cardiothoracic Imaging, a journal of the Radiological Society of North America (RSNA). “For patients with weakened immune systems, lung infections can be life threatening,” said lead study author Maximiliano Klug, M.D., a radiologist in the division of diagnostic imaging at the Sheba Medical Center in Ramat Gan, Israel. “CT scans are the gold standard for detecting pneumonia, but repeated ...

US bird populations continue alarming decline, new report finds

US bird populations continue alarming decline, new report finds
2025-03-13
ITHACA, NY.—The release of the 2025 U.S. State of the Birds report was announced today at the 90th annual North American Wildlife and Natural Resources Conference in Louisville, Kentucky. The report, produced by a coalition of leading science and conservation organizations, reveals continued widespread declines in American bird populations across all mainland and marine habitats, with 229 species requiring urgent conservation action. The report comes five years after the landmark 2019 study that documented the loss of 3 ...

RSV hospitalization risk among older adults linked to age and certain risk conditions

RSV hospitalization risk among older adults linked to age and certain risk conditions
2025-03-13
Among older adults in Spain, hospitalisation rates from respiratory syncytial virus (RSV) infection increases progressively with age and is more likely among people with other health issues and who live in nursing homes, according to a study published in Eurosurveillance. The hospitalisation rate varied considerably with age and the presence of risk conditions, with important implications for possible targeted interventions.  This population-based cohort study analysed patient data for adults over the age of 60 years in seasons 2016/17 to 2019/20 obtained through electronic medical records ...

Co-authored USF study identifies ‘surprising’ cause of sargassum blooms in Caribbean

Co-authored USF study identifies ‘surprising’ cause of sargassum blooms in Caribbean
2025-03-13
TAMPA, Fla. (March 13, 2025) – The Great Atlantic Sargassum Belt has puzzled researchers since 2011. A recent study published in Nature Communications may have identified what drove a tipping point that established the phenomenon in the tropical Atlantic Ocean. Using computer modeling, a team of international researchers demonstrated that sargassum blooms were brought to the tropics by strong ocean currents and wind and thrived in ideal growing conditions. Specifically, two consecutive years of a strong negative North Atlantic Oscillation (NAO), a shift in atmospheric pressure over the Atlantic that changes circulation and wind patterns, pushed sargassum into the tropics starting ...

Statins, aspirin may impact muscle health in smokers

2025-03-13
Miami (March 13, 2025) – For current and former smokers, statins may reduce the amount of chest muscle loss, while aspirin may contribute to increased chest muscle loss, according to a new study. The study is published in the January 2025 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open-access journal. Many people who are current or former smokers are prescribed statins to manage high cholesterol and aspirin to manage heart disease. Research has shown that current or former smokers experience increased skeletal muscle loss, especially in people ...

Retiring abroad puts older adults at risk for loneliness, study finds

2025-03-13
Many people dream of retiring to a warmer, less expensive country. But retirees who move abroad may be at greater risk of loneliness than those who stay in their home country, according to research published by the American Psychological Association.  “International retirement migration is increasingly popular in Europe and around the world. On social media you see all the people in Europe sunbathing in Spain, American retirees are moving to Mexico and Japanese retirees to Malaysia,” said study lead author Esma Betül Savaş, MSc, of the Netherlands Interdisciplinary Demographics Institute. “Although these retirement migrants generally ...

Insilico Medicine secures $110 million Series E financing to advance AI and robotics- driven drug discovery innovation

2025-03-13
Cambridge, MA, Mar 13 — Insilico Medicine(“Insilico”), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, announced today that it has successfully secured a $110 million Series E financing led by a private equity fund of Value Partners Group (HKG:0806), one of Asia’s largest independent asset management firms, with strong participation from industry- and technology-focused new investors, as well as continued support from global existing backers.  The funds raised in this round will be directed to advance Insilico's innovative drug pipeline ...

Researchers at Case Western Reserve University identify RNA molecule as possible driver of gastric cancer

Researchers at Case Western Reserve University identify RNA molecule as possible driver of gastric cancer
2025-03-13
CLEVELAND—Researchers at Case Western Reserve University have discovered molecules that present the potential to drive the development of gastric cancer—among the world’s deadliest forms of the disease. Gastric, or stomach cancer, remains one of the leading causes of cancer-related deaths, according to the American Cancer Society, because it’s difficult to diagnose at an early stage and treatments often fail once the disease has spread. But a team of researchers led by Kishore Guda, associate professor at the Digestive ...

ENDO 2025 opens media registration

2025-03-13
WASHINGTON—Members of the media can now register to cover hormone health and science advances at ENDO 2025, the Endocrine Society’s annual meeting. The meeting will take place July 12-15, in San Francisco, Calif. ENDO 2025 offers journalists the opportunity to discuss groundbreaking research with world-renowned experts in diverse fields, including obesity, diabetes, reproductive health, endocrine-disrupting chemicals, bone health and thyroid cancer. The meeting is the premier global conference in endocrinology research and clinical care. The event is expected to draw thousands of people from all over the world. This year’s program will feature ...

Study: ‘Sustainable intensification’ on the farm reduces soil nitrate losses, maintains crop yields

Study: ‘Sustainable intensification’ on the farm reduces soil nitrate losses, maintains crop yields
2025-03-13
CHAMPAIGN, Ill. — A nine-year study comparing a typical two-year corn and soybean rotation with a more intensive three-year rotation involving corn, cereal rye, soybean and winter wheat, found that the three-year system can dramatically reduce nitrogen — an important crop nutrient — in farm runoff without compromising yield. The new findings are detailed in the journal Frontiers in Environmental Science. “Subterranean drainage pipes called tiles transport nitrogen, in the form of nitrate, from fields to streams, impairing downstream surface waters,” the scientists wrote. ...
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